Works by Lerchen, Hans‐Georg
Results: 17
Neutrophil elastase as a versatile cleavage enzyme for activation of αvβ3 integrin-targeted small molecule drug conjugates with different payload classes in the tumor microenvironment.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1358393
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- Article
Inside Cover: Antibody–Drug Conjugates with Pyrrole‐Based KSP Inhibitors as the Payload Class (Angew. Chem. Int. Ed. 46/2018).
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- Angewandte Chemie International Edition, 2018, v. 57, n. 46, p. 14950, doi. 10.1002/anie.201810987
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- Article
Antibody–Drug Conjugates with Pyrrole‐Based KSP Inhibitors as the Payload Class.
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- Angewandte Chemie International Edition, 2018, v. 57, n. 46, p. 15243, doi. 10.1002/anie.201807619
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- Article
Neladenoson Bialanate Hydrochloride: A Prodrug of a Partial Adenosine A<sub>1</sub> Receptor Agonist for the Chronic Treatment of Heart Diseases.
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- ChemMedChem, 2017, v. 12, n. 10, p. 728, doi. 10.1002/cmdc.201700151
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- Article
Synthesis of Muropeptide Conjugates of 2,3-Dideoxy-β- D- manno-2-octulosonic Acid.
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- Angewandte Chemie International Edition, 1991, v. 30, n. 12, p. 1682, doi. 10.1002/anie.199116821
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- Article
Synthesis of the all- L-Configurated Cyclohexadepsipeptide cyclo-[ L-Val- L-Lac]<sub>3</sub> by the Peoc/Acid Chloride Method.
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- Angewandte Chemie International Edition, 1984, v. 23, n. 10, p. 808, doi. 10.1002/anie.198408081
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- Article
Synthesis of Cholecystokinin-Related Peptides and Their Biological Properties.
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- Biological Chemistry, 1989, v. 370, n. 1, p. 317, doi. 10.1515/bchm3.1989.370.1.317
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- Article
Antibody–Prodrug Conjugates with KSP Inhibitors and Legumain‐Mediated Metabolite Formation.
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- Chemistry - A European Journal, 2019, v. 25, n. 35, p. 8175, doi. 10.1002/chem.201901770
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- Article
Front Cover: Antibody–Prodrug Conjugates with KSP Inhibitors and Legumain‐Mediated Metabolite Formation (Chem. Eur. J. 35/2019).
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- Chemistry - A European Journal, 2019, v. 25, n. 35, p. 8171, doi. 10.1002/chem.201901769
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- Article
Antibody–Prodrug Conjugates with KSP Inhibitors and Legumain‐Mediated Metabolite Formation.
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- Chemistry - A European Journal, 2019, v. 25, n. 35, p. 8208, doi. 10.1002/chem.201900441
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- Article
Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin‐Targeted Conjugate.
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- Chemistry - A European Journal, 2019, v. 25, n. 7, p. 1696, doi. 10.1002/chem.201805447
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- Article
Discovery of VIP236, an αvβ3-Targeted Small-Molecule–Drug Conjugate with Neutrophil Elastase-Mediated Activation of 7-Ethyl Camptothecin Payload for Treatment of Solid Tumors.
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- Cancers, 2023, v. 15, n. 17, p. 4381, doi. 10.3390/cancers15174381
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- Article
A Small Molecule–Drug Conjugate (SMDC) Consisting of a Modified Camptothecin Payload Linked to an α V ß 3 Binder for the Treatment of Multiple Cancer Types.
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- Cancers, 2022, v. 14, n. 2, p. 391, doi. 10.3390/cancers14020391
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- Article
IL3RA-Targeting Antibody–Drug Conjugate BAY-943 with a Kinesin Spindle Protein Inhibitor Payload Shows Efficacy in Preclinical Models of Hematologic Malignancies.
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- Cancers, 2020, v. 12, n. 11, p. 3464, doi. 10.3390/cancers12113464
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- Article
Innentitelbild: Antikörper‐Wirkstoff‐Konjugate mit Pyrrol‐basierten KSP‐Inhibitoren als Payload‐Klasse (Angew. Chem. 46/2018).
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- Angewandte Chemie, 2018, v. 130, n. 46, p. 15166, doi. 10.1002/ange.201810987
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- Article
Antikörper‐Wirkstoff‐Konjugate mit Pyrrol‐basierten KSP‐Inhibitoren als Payload‐Klasse.
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- Angewandte Chemie, 2018, v. 130, n. 46, p. 15463, doi. 10.1002/ange.201807619
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- Article
Lectin-Mediated Drug Targeting: Discrimination of Carbohydrate-Mediated Cellular Uptake between Tumor and Liver Cells with Neoglycoconjugates Carrying Fucose Epitopes Regioselectively Modified in the 3-Position.
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- Angewandte Chemie International Edition, 1999, v. 38, n. 24, p. 3680, doi. 10.1002/(SICI)1521-3773(19991216)38:24<3680::AID-ANIE3680>3.0.CO;2-9
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- Article