Works by Lerche, Stefanie

Results: 31

Differences in age-related distribution of CSF alpha-synuclein seeding and Alzheimer profiles between PD with and without GBA1 variants.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-00978-1

By:

Lerche, Stefanie;
Wurster, Isabel;
Roeben, Benjamin;
Zimmermann, Milan;
Rossi, Marcello;
Mammana, Angela;
Baiardi, Simone;
Hauser, Ann‑Kathrin;
Deuschle, Christian;
Schulte, Claudia;
Parchi, Piero;
Brockmann, Kathrin

Publication type:

Article

Prodromal Markers in Parkinson's Disease: Limitations in Longitudinal Studies and Lessons Learned.

Published in:

Frontiers in Aging Neuroscience, 2016, p. 1, doi. 10.3389/fnagi.2016.00147

By:

Heinzel, Sebastian;
Roeben, Benjamin;
Ben-Shlomo, Yoav;
Lerche, Stefanie;
Alves, Guido;
Barone, Paolo;
Behnke, Stefanie;
Berendse, Henk W.;
Bloem, Bastiaan R.;
Burn, David;
Dodel, Richard;
Grosset, Donald G.;
Hu, Michele;
Kasten, Meike;
Krüger, Rejko;
Moccia, Marcello;
Mollenhauer, Brit;
Oertel, Wolfgang;
Suenkel, Ulrike;
Walter, Uwe

Publication type:

Article

Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies.

Published in:

Frontiers in Aging Neuroscience, 2016, p. 1, doi. 10.3389/fnagi.2016.00121

By:

Lerche, Stefanie;
Heinzel, Sebastian;
Alves, Guido W.;
Barone, Paolo;
Behnke, Stefanie;
Ben-Shlomo, Yoav;
Berendse, Henk;
Bloem, Bastiaan R.;
Burn, David;
Dodel, Richard;
Grosset, Donald G.;
Hipp, Geraldine;
Hu, Michele T.;
Kasten, Meike;
Krüger, Rejko;
Liepelt-Scarfone, Inga;
Maetzler, Walter;
Moccia, Marcello;
Mollenhauer, Brit;
Oertel, Wolfgang

Publication type:

Article

Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.

Published in:

EMBO Journal, 2008, v. 27, n. 2, p. 350, doi. 10.1038/sj.emboj.7601952

By:

Witt, Christian C.;
Witt, Stephanie H.;
Lerche, Stefanie;
Labeit, Dietmar;
Back, Walter;
Labeit, Siegfried

Publication type:

Article

Impact of APOE Genotype on Cognition in Idiopathic and Genetic Forms of Parkinson's Disease.

Published in:

Movement Disorders, 2023, v. 38, n. 5, p. 907, doi. 10.1002/mds.29399

By:

Koros, Christos;
Brockmann, Kathrin;
Simitsi, Athina‐Maria;
Bougea, Anastasia;
Liu, Hui;
Hauser, Ann‐Kathrin;
Schulte, Claudia;
Lerche, Stefanie;
Pachi, Ioanna;
Papagiannakis, Nikolaos;
Antonelou, Roubina;
Zahou, Athina;
Wurster, Isabel;
Efthymiopoulou, Efthymia;
Beratis, Ion;
Maniati, Matina;
Moraitou, Marina;
Michelakakis, Helen;
Paraskevas, Georgios;
Papageorgiou, Sokratis G.

Publication type:

Article

CSF Protein Level of Neurotransmitter Secretion, Synaptic Plasticity, and Autophagy in PD and DLB.

Published in:

Movement Disorders, 2021, v. 36, n. 11, p. 2595, doi. 10.1002/mds.28704

By:

Lerche, Stefanie;
Sjödin, Simon;
Brinkmalm, Ann;
Blennow, Kaj;
Wurster, Isabel;
Roeben, Benjamin;
Zimmermann, Milan;
Hauser, Ann‐Kathrin;
Liepelt‐Scarfone, Inga;
Waniek, Katharina;
Lachmann, Ingolf;
Gasser, Thomas;
Zetterberg, Henrik;
Brockmann, Kathrin

Publication type:

Article

The Mutation Matters: CSF Profiles of GCase, Sphingolipids, α‐Synuclein in PD<sub>GBA</sub>.

Published in:

Movement Disorders, 2021, v. 36, n. 5, p. 1216, doi. 10.1002/mds.28472

By:

Lerche, Stefanie;
Schulte, Claudia;
Wurster, Isabel;
Machetanz, Gerrit;
Roeben, Benjamin;
Zimmermann, Milan;
Deuschle, Christian;
Hauser, Ann‐Kathrin;
Böhringer, Judith;
Krägeloh‐Mann, Ingeborg;
Waniek, Katharina;
Lachmann, Ingolf;
Petterson, Xuan‐Mai T.;
Chiang, Ruby;
Park, Hyejung;
Wang, Bing;
Liepelt‐Scarfone, Inga;
Maetzler, Walter;
Galasko, Douglas;
Scherzer, Clemens R.

Publication type:

Article

CSF NFL in a Longitudinally Assessed PD Cohort: Age Effects and Cognitive Trajectories.

Published in:

2020

By:

Lerche, Stefanie;
Wurster, Isabel;
Röben, Benjamin;
Zimmermann, Milan;
Machetanz, Gerrit;
Wiethoff, Sarah;
Dehnert, Monique;
Rietschel, Lea;
Riebenbauer, Benjamin;
Deuschle, Christian;
Stransky, Elke;
Lieplt‐Scarfone, Inga;
Gasser, Thomas;
Brockmann, Kathrin;
Lieplt-Scarfone, Inga

Publication type:

journal article

Parkinson's Disease: Glucocerebrosidase 1 Mutation Severity Is Associated with CSF Alpha-Synuclein Profiles.

Published in:

2020

By:

Lerche, Stefanie;
Wurster, Isabel;
Roeben, Benjamin;
Zimmermann, Milan;
Riebenbauer, Benjamin;
Deuschle, Christian;
Hauser, Ann‐Kathrin;
Schulte, Claudia;
Berg, Daniela;
Maetzler, Walter;
Waniek, Katharina;
Lachmann, Ingolf;
Liepelt‐Scarfone, Inga;
Gasser, Thomas;
Brockmann, Kathrin;
Hauser, Ann-Kathrin;
Liepelt-Scarfone, Inga

Publication type:

journal article

Dementia with lewy bodies: GBA1 mutations are associated with cerebrospinal fluid alpha-synuclein profile.

Published in:

2019

By:

Lerche, Stefanie;
Machetanz, Gerrit;
Wurster, Isabel;
Roeben, Benjamin;
Zimmermann, Milan;
Pilotto, Andrea;
Preische, Oliver;
Stransky, Elke;
Deuschle, Christian;
Hauser, Ann‐Kathrin;
Schulte, Claudia;
Lachmann, Ingolf;
Waniek, Katharina;
Gasser, Thomas;
Berg, Daniela;
Maetzler, Walter;
Brockmann, Kathrin;
Hauser, Ann-Kathrin

Publication type:

journal article

Polygenic load: Earlier disease onset but similar longitudinal progression in Parkinson's disease.

Published in:

2018

By:

Lerche, Stefanie;
Liepelt‐Scarfone, Inga;
Wurster, Isabel;
Schulte, Claudia;
Schäffer, Eva;
Röben, Benjamin;
Machetanz, Gerrit;
Zimmermann, Milan;
Akbas, Selda;
Hauser, Ann‐Kathrin;
Gasser, Thomas;
Maetzler, Walter;
Berg, Daniela;
Brockmann, Kathrin;
Liepelt-Scarfone, Inga;
Hauser, Ann-Kathrin

Publication type:

journal article

Cognitive impairment in Glucocerebrosidase (GBA)‐associated PD: Not primarily associated with cerebrospinal fluid Abeta and Tau profiles.

Published in:

Movement Disorders, 2017, v. 32, n. 12, p. 1780, doi. 10.1002/mds.27199

By:

Lerche, Stefanie;
Schulte, Claudia;
Srulijes, Karin;
Pilotto, Andrea;
Rattay, Tim W.;
Hauser, Ann‐Kathrin;
Stransky, Elke;
Deuschle, Christian;
Csoti, Ilona;
Lachmann, Ingolf;
Zetterberg, Henrik;
Liepelt‐Scarfone, Inga;
Gasser, Thomas;
Maetzler, Walter;
Berg, Daniela;
Brockmann, Kathrin

Publication type:

Article

Application of the movement disorder society prodromal Parkinson's disease research criteria in 2 independent prospective cohorts.

Published in:

2017

By:

Pilotto, Andrea;
Heinzel, Sebastian;
Suenkel, Ulrike;
Lerche, Stefanie;
Brockmann, Kathrin;
Roeben, Benjamin;
Schaeffer, Eva;
Wurster, Isabel;
Yilmaz, Rezzak;
Liepelt‐Scarfone, Inga;
Thaler, Anna‐Katharina;
Metzger, Florian G.;
Eschweiler, Gerhard W.;
Postuma, Ron B.;
Maetzler, Walter;
Berg, Daniela

Publication type:

journal article

GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson’s Disease and Lewy Body Dementia.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0149349

By:

Maetzler, Walter;
Deleersnijder, Willy;
Hanssens, Valérie;
Bernard, Alice;
Brockmann, Kathrin;
Marquetand, Justus;
Wurster, Isabel;
Rattay, Tim W.;
Roncoroni, Lorenzo;
Schaeffer, Eva;
Lerche, Stefanie;
Apel, Anja;
Deuschle, Christian;
Berg, Daniela

Publication type:

Article

Clinical characteristics related to worsening of motor function assessed by the Unified Parkinson's Disease Rating Scale in the elderly population.

Published in:

Journal of Neurology, 2015, v. 262, n. 2, p. 451, doi. 10.1007/s00415-014-7584-4

By:

Liepelt-Scarfone, Inga;
Lerche, Stefanie;
Behnke, Stefanie;
Godau, Jana;
Gaenslen, Alexandra;
Pausch, Christoph;
Fassbender, Klaus;
Brockmann, Kathrin;
Srulijes, Karin;
Huber, Heiko;
Wurster, Isabel;
Berg, Daniela

Publication type:

Article

Risk factors and prodromal markers and the development of Parkinson's disease.

Published in:

Journal of Neurology, 2014, v. 261, n. 1, p. 180, doi. 10.1007/s00415-013-7171-0

By:

Lerche, Stefanie;
Seppi, Klaus;
Behnke, Stefanie;
Liepelt-Scarfone, Inga;
Godau, Jana;
Mahlknecht, Philipp;
Gaenslen, Alexandra;
Brockmann, Kathrin;
Srulijes, Karin;
Huber, Heiko;
Wurster, Isabel;
Stockner, Heike;
Kiechl, Stefan;
Willeit, Johann;
Gasperi, Arno;
Fassbender, Klaus;
Poewe, Werner;
Berg, Daniela

Publication type:

Article

Enlarged hyperechogenic substantia nigra as a risk marker for Parkinson's disease.

Published in:

Movement Disorders, 2013, v. 28, n. 2, p. 216, doi. 10.1002/mds.25192

By:

Berg, Daniela;
Behnke, Stefanie;
Seppi, Klaus;
Godau, Jana;
Lerche, Stefanie;
Mahlknecht, Philipp;
Liepelt‐Scarfone, Inga;
Pausch, Christoph;
Schneider, Niko;
Gaenslen, Alexandra;
Brockmann, Kathrin;
Srulijes, Karin;
Huber, Heiko;
Wurster, Isabel;
Stockner, Heike;
Kiechl, Stefan;
Willeit, Johann;
Gasperi, Arno;
Fassbender, Klaus;
Gasser, Thomas

Publication type:

Article

Association between CSF alpha-synuclein seeding activity and genetic status in Parkinson's disease and dementia with Lewy bodies.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01276-6

By:

Brockmann, Kathrin;
Quadalti, Corinne;
Lerche, Stefanie;
Rossi, Marcello;
Wurster, Isabel;
Baiardi, Simone;
Roeben, Benjamin;
Mammana, Angela;
Zimmermann, Milan;
Hauser, Ann-Kathrin;
Deuschle, Christian;
Schulte, Claudia;
Waniek, Katharina;
Lachmann, Ingolf;
Sjödin, Simon;
Brinkmalm, Ann;
Blennow, Kaj;
Zetterberg, Henrik;
Gasser, Thomas;
Parchi, Piero

Publication type:

Article

CSF and Serum Levels of Inflammatory Markers in PD: Sparse Correlation, Sex Differences and Association With Neurodegenerative Biomarkers.

Published in:

Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.834580

By:

Lerche, Stefanie;
Zimmermann, Milan;
Wurster, Isabel;
Roeben, Benjamin;
Fries, Franca Laura;
Deuschle, Christian;
Waniek, Katharina;
Lachmann, Ingolf;
Gasser, Thomas;
Jakobi, Meike;
Joos, Thomas O.;
Schneiderhan-Marra, Nicole;
Brockmann, Kathrin

Publication type:

Article

Serum and Cerebrospinal Fluid Uric Acid Levels in Lewy Body Disorders: Associations with Disease Occurrence and Amyloid-β Pathway.

Published in:

Journal of Alzheimer's Disease, 2011, v. 27, n. 1, p. 119, doi. 10.3233/JAD-2011-110587

By:

Maetzler, Walter;
Stapf, Anne Kathrin;
Schulte, Claudia;
Hauser, Ann-Kathrin;
Lerche, Stefanie;
Wurster, Isabel;
Schleicher, Erwin;
Melms, Arthur;
Berg, Daniela

Publication type:

Article

Serum and cerebrospinal fluid uric acid levels in lewy body disorders: associations with disease occurrence and amyloid-β pathway.

Published in:

2011

By:

Maetzler W;
Stapf AK;
Schulte C;
Hauser AK;
Lerche S;
Wurster I;
Schleicher E;
Melms A;
Berg D;
Maetzler, Walter;
Stapf, Anne Kathrin;
Schulte, Claudia;
Hauser, Ann-Kathrin;
Lerche, Stefanie;
Wurster, Isabel;
Schleicher, Erwin;
Melms, Arthur;
Berg, Daniela

Publication type:

journal article

Machine learning-based personalized composite score dissects risk and protective factors for cognitive and motor function in older participants.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1447944

By:

Schalkamp, Ann-Kathrin;
Lerche, Stefanie;
Wurster, Isabel;
Roeben, Benjamin;
Zimmermann, Milan;
Fries, Franca;
von Thaler, Anna-Katharina;
Eschweiler, Gerhard;
Maetzler, Walter;
Berg, Daniela;
Sinz, Fabian H.;
Brockmann, Kathrin

Publication type:

Article

Mild Parkinsonian Signs in the Elderly – Is There an Association with PD? Crossectional Findings in 992 Individuals.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092878

By:

Lerche, Stefanie;
Hobert, Markus;
Brockmann, Kathrin;
Wurster, Isabel;
Gaenslen, Alexandra;
Hasmann, Sandra;
Eschweiler, Gerhard W.;
Maetzler, Walter;
Berg, Daniela

Publication type:

Article

CSF α-synuclein seed amplification kinetic profiles are associated with cognitive decline in Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-023-00627-5

By:

Brockmann, Kathrin;
Lerche, Stefanie;
Baiardi, Simone;
Rossi, Marcello;
Wurster, Isabel;
Quadalti, Corinne;
Roeben, Benjamin;
Mammana, Angela;
Zimmermann, Milan;
Hauser, Ann‑Kathrin;
Deuschle, Christian;
Schulte, Claudia;
Liepelt-Scarfone, Inga;
Gasser, Thomas;
Parchi, Piero

Publication type:

Article

Inflammatory CSF profiles and longitudinal development of cognitive decline in sporadic and GBA-associated PD.

Published in:

NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00476-2

By:

Lerche, Stefanie;
Zimmermann, Milan;
Roeben, Benjamin;
Wurster, Isabel;
Fries, Franca Laura;
Deuschle, Christian;
Waniek, Katharina;
Lachmann, Ingolf;
Jakobi, Meike;
Joos, Thomas O.;
Knorpp, Thomas;
Schneiderhan-Marra, Nicole;
Brockmann, Kathrin

Publication type:

Article

Association of elevated cerebrospinal fluid levels of the longevity protein α‐Klotho with a delayed onset of cognitive impairment in Parkinson's disease patients.

Published in:

European Journal of Neurology, 2024, v. 31, n. 10, p. 1, doi. 10.1111/ene.16388

By:

Zimmermann, Milan;
Fandrich, Madeleine;
Jakobi, Meike;
Röben, Benjamin;
Wurster, Isabel;
Lerche, Stefanie;
Schulte, Claudia;
Zimmermann, Shahrzad;
Deuschle, Christian;
Schneiderhan‐Marra, Nicole;
Gasser, Thomas;
Brockmann, Kathrin

Publication type:

Article

The longevity gene Klotho and its cerebrospinal fluid protein profiles as a modifier for Parkinson´s disease.

Published in:

European Journal of Neurology, 2021, v. 28, n. 5, p. 1557, doi. 10.1111/ene.14733

By:

Zimmermann, Milan;
Köhler, Leonie;
Kovarova, Marketa;
Lerche, Stefanie;
Schulte, Claudia;
Wurster, Isabel;
Machetanz, Gerrit;
Deuschle, Christian;
Hauser, Ann‐Kathrin;
Gasser, Thomas;
Berg, Daniela;
Schleicher, Erwin;
Maetzler, Walter;
Brockmann, Kathrin

Publication type:

Article

CSF d18:1 sphingolipid species in Parkinson disease and dementia with Lewy bodies with and without GBA1 variants.

Published in:

NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00820-0

By:

Lerche, Stefanie;
Wurster, Isabel;
Valente, Enza Maria;
Avenali, Micol;
Samaniego, Daniela;
Martínez-Vicente, Marta;
Hernández-Vara, Jorge;
Laguna, Ariadna;
Sturchio, Andrea;
Svenningsson, Per;
France, Nicholas P.;
Barlow, Carrolee;
Sankaranarayanan, Sethu;
Brockmann, Kathrin

Publication type:

Article

Longitudinal cognitive decline characterizes the profile of non-PD-manifest GBA1 mutation carriers.

Published in:

NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00706-1

By:

Roeben, Benjamin;
Liepelt-Scarfone, Inga;
Lerche, Stefanie;
Zimmermann, Milan;
Wurster, Isabel;
Sünkel, Ulrike;
Schulte, Claudia;
Deuschle, Christian;
Eschweiler, Gerhard W.;
Maetzler, Walter;
Gasser, Thomas;
Berg, Daniela;
Brockmann, Kathrin

Publication type:

Article

Methods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease - Report of the JPND Working Group BioLoC-PD.

Published in:

Neuroepidemiology, 2015, v. 45, n. 4, p. 282, doi. 10.1159/000439221

By:

Lerche, Stefanie;
Liepelt-Scarfone, Inga;
alves, Guido;
Barone, Paolo;
Behnke, Stefanie;
Ben-Shlomo, Yoav;
Berendse, Henk;
Burn, David;
Dodel, Richard;
Grosset, Donald;
Heinzel, Sebastian;
Hu, Michele;
Kasten, Meike;
Krüger, Rejko;
Maetzler, Walter;
Moccia, Marcello;
Mollenhauer, Brit;
Oertel, Wolfgang;
Roeben, Benjamin;
Sünkel, Ulrike

Publication type:

Article

Prospective longitudinal course of cognition in older subjects with mild parkinsonian signs.

Published in:

Alzheimer's Research & Therapy, 2016, v. 8, p. 1, doi. 10.1186/s13195-016-0209-7

By:

Lerche, Stefanie;
Brockmann, Kathrin;
Wurster, Isabel;
Sünkel, Ulrike;
Hobert, Markus A.;
von Thaler, Anna-Katharina;
Schulte, Claudia;
Maetzler, Walter;
Berg, Daniela;
Pilotto, Andrea;
Stoops, Erik;
Vanderstichele, Hugo;
Herbst, Victor;
Brix, Britta;
Eschweiler, Gerhard W.;
Metzger, Florian G.

Publication type:

Article