Works by Leong, Chee-Onn

Results: 37

A hierarchical cluster analysis for clinical profiling of tofacitinib treatment response in patients with rheumatoid arthritis.
Published in:
Clinical Rheumatology, 2024, v. 43, n. 8, p. 2489, doi. 10.1007/s10067-024-07035-x
By:
- Janahiraman, Sivakami;
- Shahril, Nor Shuhaila;
- Jayaraj, Vivek Jason;
- Ch'ng, Suyin;
- Eow, Liu Hong;
- Mageswaren, Eashwary;
- Lim, Ai Lee;
- Chong, Hwee Cheng;
- Ong, Ping Seung;
- Ismail, Asmahan Mohamed;
- Rahim, Siti Mariam Ab;
- Ng, Chun Ruh;
- Suahilai, Dayang Masyrinartie;
- Ramlan, Azwarina Hanim;
- Too, Chun Lai;
- Leong, Chee Onn
Publication type:
Article
Association of BRCA1- and BRCA2-deficiency with mutation burden, expression of PD-L1/PD-1, immune infiltrates, and T cell-inflamed signature in breast cancer.
Published in:
PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0215381
By:
- Wen, Wei Xiong;
- Leong, Chee-Onn
Publication type:
Article
A genotype imputation reference panel specific for native Southeast Asian populations.
Published in:
NPJ Genomic Medicine, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41525-024-00435-7
By:
- Cengnata, Alvin;
- Deng, Lian;
- Yap, Wai-Sum;
- Lim, Lay-Hong Renee;
- Leong, Chee-Onn;
- Xu, Shuhua;
- Hoh, Boon-Peng
Publication type:
Article
The Role of Ras-Associated Protein 1 (Rap1) in Cancer: Bad Actor or Good Player?
Published in:
Biomedicines, 2020, v. 8, n. 9, p. 334, doi. 10.3390/biomedicines8090334
By:
- Looi, Chin-King;
- Hii, Ling-Wei;
- Ngai, Siew Ching;
- Leong, Chee-Onn;
- Mai, Chun-Wai
Publication type:
Article
Sphingosine Kinase 1 Regulates the Survival of Breast Cancer Stem Cells and Non-stem Breast Cancer Cells by Suppression of STAT1.
Published in:
Cells (2073-4409), 2020, v. 9, n. 4, p. 886, doi. 10.3390/cells9040886
By:
- Hii, Ling-Wei;
- Chung, Felicia Fei-Lei;
- Mai, Chun Wai;
- Yee, Zong Yang;
- Chan, Hong Hao;
- Raja, Vijay Joseph;
- Dephoure, Noah Elias;
- Pyne, Nigel J.;
- Pyne, Susan;
- Leong, Chee-Onn
Publication type:
Article
Genetic Biomarkers as Predictors of Response to Tocilizumab in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.
Published in:
Genes, 2022, v. 13, n. 7, p. 1284, doi. 10.3390/genes13071284
By:
- Janahiraman, Sivakami;
- Too, Chun Lai;
- Lee, Kai Wei;
- Shahril, Nor Shuhaila;
- Leong, Chee Onn
Publication type:
Article
Roles of receptor‐interacting protein kinase 1 in SH‐SY5Y cells with beta amyloid‐induced neurotoxicity.
Published in:
Journal of Cellular & Molecular Medicine, 2022, v. 26, n. 5, p. 1434, doi. 10.1111/jcmm.17095
By:
- Chan, Hong‐Hao;
- Leong, Chee‐Onn;
- Lim, Chooi‐Ling;
- Koh, Rhun‐Yian
Publication type:
Article
Inhibition of Janus Kinase 1 synergizes docetaxel sensitivity in prostate cancer cells.
Published in:
Journal of Cellular & Molecular Medicine, 2021, v. 25, n. 17, p. 8187, doi. 10.1111/jcmm.16684
By:
- Nalairndran, Geetha;
- Chung, Ivy;
- Abdul Razack, Azad Hassan;
- Chung, Felicia Fei‐Lei;
- Hii, Ling‐Wei;
- Lim, Wei‐Meng;
- Looi, Chin King;
- Mai, Chun‐Wai;
- Leong, Chee‐Onn
Publication type:
Article
Phosphoinositide‐dependent Kinase‐1 (PDPK1) regulates serum/glucocorticoid‐regulated Kinase 3 (SGK3) for prostate cancer cell survival.
Published in:
Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 20, p. 12188, doi. 10.1111/jcmm.15876
By:
- Nalairndran, Geetha;
- Hassan Abdul Razack, Azad;
- Mai, Chun‐Wai;
- Fei‐Lei Chung, Felicia;
- Chan, Kok‐Keong;
- Hii, Ling‐Wei;
- Lim, Wei‐Meng;
- Chung, Ivy;
- Leong, Chee‐Onn
Publication type:
Article
N, N'‐Disubstituted Benzimidazolium Salts: Synthesis, Characterization, Micromolar Detection of Fe(III) ions in Aqueous system, Biological Evaluation and Molecular Docking Studies.
Published in:
ChemistrySelect, 2022, v. 7, n. 48, p. 1, doi. 10.1002/slct.202203239
By:
- Sharma, Himshikha;
- Chaudhary, Shweta;
- Nirwan, Sonam;
- Kakkar, Rita;
- Liew, HuiShan;
- Low, May‐Lee;
- Mai, Chun‐Wai;
- Hii, Ling‐Wei;
- Leong, Chee‐Onn;
- Daisy Milton, Marilyn
Publication type:
Article
Advances in Nanomaterials Used in Co-Delivery of siRNA and Small Molecule Drugs for Cancer Treatment.
Published in:
Nanomaterials (2079-4991), 2021, v. 11, n. 10, p. 2467, doi. 10.3390/nano11102467
By:
- Chung, Shei Li;
- Yee, Maxine Swee-Li;
- Hii, Ling-Wei;
- Lim, Wei-Meng;
- Ho, Mui Yen;
- Khiew, Poi Sim;
- Leong, Chee-Onn
Publication type:
Article
Impact of Microplastics and Nanoplastics on Human Health.
Published in:
Nanomaterials (2079-4991), 2021, v. 11, n. 2, p. 496, doi. 10.3390/nano11020496
By:
- Yee, Maxine Swee-Li;
- Hii, Ling-Wei;
- Looi, Chin King;
- Lim, Wei-Meng;
- Wong, Shew-Fung;
- Kok, Yih-Yih;
- Tan, Boon-Keat;
- Wong, Chiew-Yen;
- Leong, Chee-Onn;
- Liao, Vivian Hsiu-Chuan
Publication type:
Article
The synergism of Clinacanthus nutans Lindau extracts with gemcitabine: downregulation of anti-apoptotic markers in squamous pancreatic ductal adenocarcinoma.
Published in:
BMC Complementary & Alternative Medicine, 2019, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12906-019-2663-9
By:
- Hii, Ling-Wei;
- Lim, Swee-Hua Erin;
- Leong, Chee-Onn;
- Chin, Swee-Yee;
- Tan, Ngai-Paing;
- Lai, Kok-Song;
- Mai, Chun-Wai
Publication type:
Article
Author Correction: Mitochondrial DNA alterations may influence the cisplatin responsiveness of oral squamous cell carcinoma.
Published in:
2021
By:
- Aminuddin, Amnani;
- Ng, Pei Yuen;
- Leong, Chee-Onn;
- Chua, Eng Wee
Publication type:
Correction Notice
Contrasting sirtuin and poly( ADP-ribose)polymerase activities of selected 2,4,6-trisubstituted benzimidazoles.
Published in:
Chemical Biology & Drug Design, 2018, v. 91, n. 1, p. 213, doi. 10.1111/cbdd.13072
By:
- Yeong, Keng Yoon;
- Tan, Soo Choon;
- Mai, Chun‐Wai;
- Leong, Chee‐Onn;
- Chung, Felicia Fei‐Lei;
- Lee, Yean Kee;
- Chee, Chin Fei;
- Abdul Rahman, Noorsaadah
Publication type:
Article
Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1).
Published in:
Scientific Reports, 2017, p. 42504, doi. 10.1038/srep42504
By:
- Chung, Felicia Fei-Lei;
- Tan, Perry Faith Tze Ming;
- Raja, Vijay Joseph;
- Tan, Boon-Shing;
- Lim, Kuan-Hon;
- Kam, Toh-Seok;
- Hii, Ling-Wei;
- Tan, Si Hoey;
- See, Sze-Jia;
- Tan, Yuen-Fen;
- Wong, Li-Zhe;
- Yam, Wai Keat;
- Mai, Chun Wai;
- Bradshaw, Tracey D.;
- Leong, Chee-Onn
Publication type:
Article
Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1153-8
By:
- Looi, Chin-King;
- Chung, Felicia Fei-Lei;
- Leong, Chee-Onn;
- Wong, Shew-Fung;
- Rosli, Rozita;
- Mai, Chun-Wai
Publication type:
Article
Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway.
Published in:
PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170551
By:
- Soo, Hsien-Chuen;
- Chung, Felicia Fei-Lei;
- Lim, Kuan-Hon;
- Yap, Veronica Alicia;
- Bradshaw, Tracey D.;
- Hii, Ling-Wei;
- Tan, Si-Hoey;
- See, Sze-Jia;
- Tan, Yuen-Fen;
- Leong, Chee-Onn;
- Mai, Chun-Wai
Publication type:
Article
Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1108, doi. 10.3390/ijms23031108
By:
- Pua, Lesley Jia Wei;
- Mai, Chun-Wai;
- Chung, Felicia Fei-Lei;
- Khoo, Alan Soo-Beng;
- Leong, Chee-Onn;
- Lim, Wei-Meng;
- Hii, Ling-Wei
Publication type:
Article
Toxicity of single-walled carbon nanotubes.
Published in:
Archives of Toxicology, 2016, v. 90, n. 1, p. 103, doi. 10.1007/s00204-014-1376-6
By:
- Ong, Li-Chu;
- Chung, Felicia;
- Tan, Yuen-Fen;
- Leong, Chee-Onn
Publication type:
Article
An evaluation of tocotrienol ethosomes for transdermal delivery using Strat-M<sup>®</sup> membrane and excised human skin.
Published in:
Pharmaceutical Development & Technology, 2021, v. 26, n. 2, p. 243, doi. 10.1080/10837450.2020.1860087
By:
- Nair, Rajesh Sreedharan;
- Billa, Nashiru;
- Leong, Chee-Onn;
- Morris, Andrew P.
Publication type:
Article
Novel antitumour indole alkaloid, Jerantinine A, evokes potent G2/M cell cycle arrest targeting microtubules.
Published in:
Investigational New Drugs, 2014, v. 32, n. 5, p. 838, doi. 10.1007/s10637-014-0126-1
By:
- Raja, Vijay;
- Lim, Kuan-Hon;
- Leong, Chee-Onn;
- Kam, Toh-Seok;
- Bradshaw, Tracey
Publication type:
Article
Nasopharyngeal Carcinoma and Its Microenvironment: Past, Current, and Future Perspectives.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.840467
By:
- Su, Zhi Yi;
- Siak, Pui Yan;
- Leong, Chee-Onn;
- Cheah, Shiau-Chuen
Publication type:
Article
Histone Deacetylase Inhibitors Restore Cancer Cell Sensitivity towards T Lymphocytes Mediated Cytotoxicity in Pancreatic Cancer.
Published in:
Cancers, 2022, v. 14, n. 15, p. 3709, doi. 10.3390/cancers14153709
By:
- Looi, Chin-King;
- Gan, Li-Lian;
- Sim, Wynne;
- Hii, Ling-Wei;
- Chung, Felicia Fei-Lei;
- Leong, Chee-Onn;
- Lim, Wei-Meng;
- Mai, Chun-Wai
Publication type:
Article
Current Status and Future Perspectives about Molecular Biomarkers of Nasopharyngeal Carcinoma.
Published in:
Cancers, 2021, v. 13, n. 14, p. 3490, doi. 10.3390/cancers13143490
By:
- Siak, Pui Yan;
- Khoo, Alan Soo-Beng;
- Leong, Chee Onn;
- Hoh, Boon-Peng;
- Cheah, Shiau-Chuen
Publication type:
Article
Roles of Inflammasomes in Epstein–Barr Virus-Associated Nasopharyngeal Cancer.
Published in:
Cancers, 2021, v. 13, n. 8, p. 1786, doi. 10.3390/cancers13081786
By:
- Looi, Chin King;
- Hii, Ling-Wei;
- Chung, Felicia Fei-Lei;
- Mai, Chun-Wai;
- Lim, Wei-Meng;
- Leong, Chee-Onn;
- Mosialos, George
Publication type:
Article
Molecular Mechanisms and Potential Therapeutic Reversal of Pancreatic Cancer-Induced Immune Evasion.
Published in:
Cancers, 2020, v. 12, n. 7, p. 1872, doi. 10.3390/cancers12071872
By:
- Gan, Li-Lian;
- Hii, Ling-Wei;
- Wong, Shew-Fung;
- Leong, Chee-Onn;
- Mai, Chun-Wai
Publication type:
Article
Targeting the crosstalk of epigenetic modifications and immune evasion in nasopharyngeal cancer.
Published in:
Cell Biology & Toxicology, 2023, v. 39, n. 6, p. 2501, doi. 10.1007/s10565-023-09830-9
By:
- Looi, Chin-King;
- Foong, Lian-Chee;
- Chung, Felicia Fei-Lei;
- Khoo, Alan Soo-Beng;
- Loo, Ee-Mun;
- Leong, Chee-Onn;
- Mai, Chun-Wai
Publication type:
Article
Identification of inhibitors synergizing gemcitabine sensitivity in the squamous subtype of pancreatic ductal adenocarcinoma (PDAC).
Published in:
Apoptosis, 2018, v. 23, n. 5/6, p. 343, doi. 10.1007/s10495-018-1459-6
By:
- Er, Jia Lin;
- Goh, Pei Ni;
- Lee, Chen Yuan;
- Tan, Ying Jie;
- Hii, Ling-Wei;
- Mai, Chun Wai;
- Chung, Felicia Fei-Lei;
- Leong, Chee-Onn
Publication type:
Article
Metformin synergizes 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) combination therapy through impairing intracellular ATP production and DNA repair in breast cancer stem cells.
Published in:
Apoptosis, 2015, v. 20, n. 10, p. 1373, doi. 10.1007/s10495-015-1158-5
By:
- Soo, Jaslyn;
- Ng, Char-Hong;
- Tan, Si;
- Malik, Rozita;
- Teh, Yew-Ching;
- Tan, Boon-Shing;
- Ho, Gwo-Fuang;
- See, Mee-Hoong;
- Taib, Nur;
- Yip, Cheng-Har;
- Chung, Felicia;
- Hii, Ling-Wei;
- Teo, Soo-Hwang;
- Leong, Chee-Onn
Publication type:
Article
Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers.
Published in:
Apoptosis, 2013, v. 18, n. 12, p. 1447, doi. 10.1007/s10495-013-0886-7
By:
- Tiong, Kai Hung;
- Mah, Li Yen;
- Leong, Chee-Onn
Publication type:
Article
Mitochondrial DNA alterations may influence the cisplatin responsiveness of oral squamous cell carcinoma.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64664-3
By:
- Aminuddin, Amnani;
- Ng, Pei Yuen;
- Leong, Chee-Onn;
- Chua, Eng Wee
Publication type:
Article
Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells.
Published in:
Cutaneous & Ocular Toxicology, 2018, v. 37, n. 1, p. 52, doi. 10.1080/15569527.2017.1335748
By:
- Chong, You Sheng;
- Mai, Chun Wai;
- Leong, Chee Onn;
- Wong, Lai Chun
Publication type:
Article
Histone deacetylase (HDAC) inhibitors and doxorubicin combinations target both breast cancer stem cells and non-stem breast cancer cells simultaneously.
Published in:
Breast Cancer Research & Treatment, 2020, v. 179, n. 3, p. 615, doi. 10.1007/s10549-019-05504-5
By:
- Hii, Ling-Wei;
- Chung, Felicia Fei-Lei;
- Soo, Jaslyn Sian-Siu;
- Tan, Boon Shing;
- Mai, Chun-Wai;
- Leong, Chee-Onn
Publication type:
Article
Rapamycin synergizes cisplatin sensitivity in basal-like breast cancer cells through up-regulation of p73.
Published in:
Breast Cancer Research & Treatment, 2011, v. 128, n. 2, p. 301, doi. 10.1007/s10549-010-1055-0
By:
- Wong, Su;
- Tiong, Kai;
- Kong, Weng;
- Yue, Yuen;
- Chua, Choon;
- Lim, Jae;
- Lee, Chai;
- Quah, Sean;
- Fow, Cindy;
- Chung, Cyril;
- So, Irene;
- Tan, Boon;
- Choo, Heng;
- Rosli, Rozita;
- Cheong, Soon-Keng;
- Leong, Chee-Onn
Publication type:
Article
Potential role of heteroplasmic mitochondrial DNA mutations in modulating the subtype-specific adaptation of oral squamous cell carcinoma to cisplatin therapy.
Published in:
Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01445-8
By:
- Aminuddin, Amnani;
- Ng, Pei Yuen;
- Leong, Chee Onn;
- Makpol, Suzana;
- Chua, Eng Wee
Publication type:
Article
An Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles for Transdermal Delivery.
Published in:
AAPS PharmSciTech, 2019, v. 20, n. 2, p. 1, doi. 10.1208/s12249-018-1279-6
By:
- Nair, Rajesh Sreedharan;
- Morris, Andrew;
- Billa, Nashiru;
- Leong, Chee-Onn
Publication type:
Article