Works matching AU Lenka, Besse

Results: 26

Correction: Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma.

Published in:

2025

By:

Bandini, Cecilia;
Mereu, Elisabetta;
Paradzik, Tina;
Labrador, Maria;
Maccagno, Monica;
Cumerlato, Michela;
Oreglia, Federico;
Prever, Lorenzo;
Manicardi, Veronica;
Taiana, Elisa;
Ronchetti, Domenica;
D'Agostino, Mattia;
Gay, Francesca;
Larocca, Alessandra;
Besse, Lenka;
Merlo, Giorgio Roberto;
Hirsch, Emilio;
Ciarrocchi, Alessia;
Inghirami, Giorgio;
Neri, Antonino

Publication type:

Correction Notice

Improving the efficacy of proteasome inhibitors in the treatment of renal cell carcinoma by combination with the human immunodeficiency virus (HIV)‐protease inhibitors lopinavir or nelfinavir.

Published in:

BJU International, 2018, v. 121, n. 4, p. 600, doi. 10.1111/bju.14083

By:

Abt, Dominik;
Besse, Andrej;
Sedlarikova, Lenka;
Kraus, Marianne;
Bader, Juergen;
Silzle, Tobias;
Vodinska, Martina;
Slaby, Ondrej;
Schmid, Hans‐Peter;
Engeler, Daniel Stephan;
Driessen, Christoph;
Besse, Lenka

Publication type:

Article

P-158: Carfilzomib-induced acute cardiotoxicity is mediated through angiotensin and caused by cardiomyocyte energy depletion.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S122, doi. 10.1016/S2152-2650(21)02285-0

By:

Mendez, Max;
Andrej, Besse;
Florea, Bogdan;
Christian, Zuppinger;
Overkleeft, Hermen;
Lenka, Besse;
Driessen, Christoph

Publication type:

Article

P-091: Genome-wide CRISPR/Cas9 screening identifies proteasome-related specific vulnerabilities as potential treatment options of proteasome inhibitor-resistant multiple myeloma.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S88, doi. 10.1016/S2152-2650(21)02225-4

By:

Andrej, Besse;
Lenka, Besse;
Büchler, Lorina;
Stolze, Sara;
Sobh, Amin;
Kraus, Marianne;
Nakagami, Hirofumi;
Driessen, Christoph

Publication type:

Article

Nelfinavir interacts with mitochondrial VDACs and disrupts oxidative phosphorylation in proteasome inhibitor resistant myeloma.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e125, doi. 10.1016/j.clml.2019.09.207

By:

Besse, Andrej;
Besse, Lenka;
Stolze, Sara Christina;
Zaal, Esther;
Berkers, Celia;
Everts, Bart;
Phuyal, Santosh;
Kraus, Marianne;
Sobh, Amin;
Silzle, Tobias;
Vulpe, Christopher;
Farhan, Hesso;
Overkleeft, Herman S.;
Driessen, Christoph

Publication type:

Article

Proteasome inhibition by Carfilzomib, but not by Bortezomib, induces a specific, proteasome subunit-dependent impairment in cardiac contractility.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e119, doi. 10.1016/j.clml.2019.09.197

By:

Mendez, Max;
Besse, Andrej;
Besse, Lenka;
Florea, Bogdan;
Christian, Zuppinger;
Overkleeft, Herman S.;
Driessen, Christoph

Publication type:

Article

EDO-S101, an Alkylating-HDAC-Inhibitor, is Synergistic With Proteasome Inhibition Against Multiple Myeloma Through Activation of Multiple Pathways.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2017, v. 17, p. e31, doi. 10.1016/j.clml.2017.03.053

By:

Besse, Lenka;
Kraus, Marianne;
Besse, Andrej;
Bader, Juergen;
Mehrling, Thomas;
Driessen, Christoph

Publication type:

Article

Expression of MDR1 Mediates Carfilzomib Resistance in MM and PCL Patients and May be Overcome by HIV Protease Inhibitors Nelfinavir and Lopinavir.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2017, v. 17, p. e32, doi. 10.1016/j.clml.2017.03.054

By:

Besse, Andrej;
Besse, Lenka;
Stolze, Sara C.;
Rasche, Leo;
Weinhold, Niels;
Morgan, Gareth;
Kraus, Marianne;
Bader, Juergen;
Overkleeft, Herman S.;
Driessen, Christoph

Publication type:

Article

The novel β2-selective proteasome inhibitor LU-102 decreases phosphorylation of I kappa B and induces highly synergistic cytotoxicity in combination with ibrutinib in multiple myeloma cells.

Published in:

2015

By:

Kraus, Johannes;
Kraus, Marianne;
Liu, Nora;
Besse, Lenka;
Bader, Jürgen;
Geurink, Paul P;
de Bruin, Gerjan;
Kisselev, Alexei F;
Overkleeft, Herman;
Driessen, Christoph

Publication type:

journal article

The novel β2-selective proteasome inhibitor LU-102 decreases phosphorylation of I kappa B and induces highly synergistic cytotoxicity in combination with ibrutinib in multiple myeloma cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 76, n. 2, p. 383, doi. 10.1007/s00280-015-2801-0

By:

Kraus, Johannes;
Kraus, Marianne;
Liu, Nora;
Besse, Lenka;
Bader, Jürgen;
Geurink, Paul;
Bruin, Gerjan;
Kisselev, Alexei;
Overkleeft, Herman;
Driessen, Christoph

Publication type:

Article

Selected Genetic Polymorphisms Associated with Hypoxia and Multidrug Resistance in Monoclonal Gammopathies Patients.

Published in:

Journal of the Czech & Slovak Societies for Oncology / Klinická Onkologie, 2018, v. 31, n. 3, p. 213, doi. 10.14735/amko2018213

By:

Martina, Almasi;
Lenka, Besse;
Lucie, Brozova;
Jiri, Jarkovsky;
Renata, Bezdekova;
Ludek, Pour;
Jiri, Minarik;
Petr, Kessler;
Petr, Pavlicek;
Lubica, Roziakova;
Miroslav, Penka;
Roman, Hájek;
Anna, Vasku;
Sabina, Sevcikova

Publication type:

Article

Extramedullary relapse of multiple myeloma defined as the highest risk group based on deregulated gene expression data.

Published in:

Biomedical Papers of the Medical Faculty of Palacky University in Olomouc, 2015, v. 159, n. 2, p. 288, doi. 10.5507/bp.2015.014

By:

Sevcikova, Sabina;
Paszekova, Helena;
Besse, Lenka;
Sedlarikova, Lenka;
Kubaczkova, Veronika;
Almasi, Martina;
Pour, Ludek;
Hajek, Roman

Publication type:

Article

The potential of CRISPR/Cas9 genome editing for the study and treatment of intervertebral disc pathologies.

Published in:

JOR Spine, 2018, v. 1, n. 1, p. 1, doi. 10.1002/jsp2.1003

By:

Krupkova, Olga;
Cambria, Elena;
Besse, Lenka;
Besse, Andrej;
Bowles, Robert;
Wuertz-Kozak, Karin

Publication type:

Article

Dynamics of tumor‐specific cfDNA in response to therapy in multiple myeloma patients.

Published in:

European Journal of Haematology, 2020, v. 104, n. 3, p. 190, doi. 10.1111/ejh.13358

By:

Vrabel, David;
Sedlarikova, Lenka;
Besse, Lenka;
Rihova, Lucie;
Bezdekova, Renata;
Almasi, Martina;
Kubaczkova, Veronika;
Brožová, Lucie;
Jarkovsky, Jiri;
Plonkova, Hana;
Jelinek, Tomas;
Sandecka, Viera;
Stork, Martin;
Pour, Ludek;
Sevcikova, Sabina;
Hajek, Roman

Publication type:

Article

Cell-free DNA - Minimally invasive marker of hematological malignancies.

Published in:

European Journal of Haematology, 2017, v. 99, n. 4, p. 291, doi. 10.1111/ejh.12925

By:

Kubaczkova, Veronika;
Vrabel, David;
Sedlarikova, Lenka;
Besse, Lenka;
Sevcikova, Sabina

Publication type:

Article

Cytogenetics in multiple myeloma patients progressing into extramedullary disease.

Published in:

European Journal of Haematology, 2016, v. 97, n. 1, p. 93, doi. 10.1111/ejh.12688

By:

Besse, Lenka;
Sedlarikova, Lenka;
Greslikova, Henrieta;
Kupska, Renata;
Almasi, Martina;
Penka, Miroslav;
Jelinek, Tomas;
Pour, Ludek;
Adam, Zdenek;
Kuglik, Petr;
Krejci, Marta;
Hajek, Roman;
Sevcikova, Sabina

Publication type:

Article

Circulating Serum MicroRNA-130a as a Novel Putative Marker of Extramedullary Myeloma.

Published in:

PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0137294

By:

Besse, Lenka;
Sedlarikova, Lenka;
Kryukov, Fedor;
Nekvindova, Jana;
Radova, Lenka;
Slaby, Ondrej;
Kuglik, Petr;
Almasi, Martina;
Penka, Miroslav;
Krejci, Marta;
Adam, Zdenek;
Pour, Ludek;
Sevcikova, Sabina;
Hajek, Roman

Publication type:

Article

Immunoproteasome Activity in Chronic Lymphocytic Leukemia as a Target of the Immunoproteasome-Selective Inhibitors.

Published in:

Cells (2073-4409), 2022, v. 11, n. 5, p. 838, doi. 10.3390/cells11050838

By:

Besse, Andrej;
Kraus, Marianne;
Mendez-Lopez, Max;
Maurits, Elmer;
Overkleeft, Herman S.;
Driessen, Christoph;
Besse, Lenka

Publication type:

Article

High Immunoproteasome Activity and sXBP1 in Pediatric Precursor B-ALL Predicts Sensitivity towards Proteasome Inhibitors.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 2853, doi. 10.3390/cells10112853

By:

Besse, Lenka;
Besse, Andrej;
Kraus, Marianne;
Maurits, Elmer;
Overkleeft, Herman S.;
Bornhauser, Beat;
Bourquin, Jean-Pierre;
Driessen, Christoph

Publication type:

Article

HIV Protease Inhibitors for the Treatment of Multiple Myeloma.

Published in:

Clinical Advances in Hematology & Oncology, 2019, v. 17, n. 11, p. 615

By:

Mendez-Lopez, Max;
Sutter, Tabea;
Driessen, Christoph;
Besse, Lenka

Publication type:

Article

HIV-protease inhibitors potentiate the activity of carfilzomib in triple-negative breast cancer.

Published in:

British Journal of Cancer, 2024, v. 131, n. 5, p. 918, doi. 10.1038/s41416-024-02774-9

By:

Besse, Andrej;
Sedlarikova, Lenka;
Buechler, Lorina;
Kraus, Marianne;
Yang, Chieh-Hsiang;
Strakova, Nicol;
Soucek, Karel;
Navratil, Jiri;
Svoboda, Marek;
Welm, Alana L.;
Joerger, Markus;
Driessen, Christoph;
Besse, Lenka

Publication type:

Article

The cytotoxic activity of carfilzomib together with nelfinavir is superior to the bortezomib/nelfinavir combination in non-small cell lung carcinoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-31400-6

By:

Besse, Lenka;
Kraus, Marianne;
Besse, Andrej;
Driessen, Christoph;
Tarantino, Ignazio

Publication type:

Article

Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma.

Published in:

Experimental Hematology & Oncology, 2023, v. 12, n. 1, p. 1, doi. 10.1186/s40164-023-00434-x

By:

Bandini, Cecilia;
Mereu, Elisabetta;
Paradzik, Tina;
Labrador, Maria;
Maccagno, Monica;
Cumerlato, Michela;
Oreglia, Federico;
Prever, Lorenzo;
Manicardi, Veronica;
Taiana, Elisa;
Ronchetti, Domenica;
D'Agostino, Mattia;
Gay, Francesca;
Larocca, Alessandra;
Besse, Lenka;
Merlo, Giorgio Roberto;
Hirsch, Emilio;
Ciarrocchi, Alessia;
Inghirami, Giorgio;
Neri, Antonino

Publication type:

Article

Contribution of the Tumor Microenvironment to Metabolic Changes Triggering Resistance of Multiple Myeloma to Proteasome Inhibitors.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.899272

By:

Schwestermann, Jonas;
Besse, Andrej;
Driessen, Christoph;
Besse, Lenka

Publication type:

Article

MicroRNAs in urine are not biomarkers of multiple myeloma.

Published in:

Journal of Negative Results in Biomedicine, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12952-015-0035-7

By:

Sedlaříková, Lenka;
Bešše, Lenka;
Novosadová, Soňa;
Kubaczková, Veronika;
Radová, Lenka;
Staník, Michal;
Krejčí, Marta;
Hájek, Roman;
Ševčíková, Sabina

Publication type:

Article

Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia.

Published in:

American Journal of Hematology, 2015, v. 90, n. 3, p. E51, doi. 10.1002/ajh.23910

By:

Kubiczkova Besse, Lenka;
Sedlarikova, Lenka;
Kryukov, Fedor;
Nekvindova, Jana;
Radova, Lenka;
Almasi, Martina;
Pelcova, Jana;
Minarik, Jiri;
Pika, Tomas;
Pikalova, Zuzana;
Scudla, Vlastimil;
Krejci, Marta;
Adam, Zdenek;
Pour, Ludek;
Hajek, Roman;
Sevcikova, Sabina

Publication type:

Article