Works by Lemech, Charlotte

Results: 26

Safety, Pharmacokinetics and Preliminary Efficacy of IL4-Rα Monoclonal Antibody AK120 in Both Healthy and Atopic Dermatitis Subjects: A Phase I, Randomized, Two-Part, Double-Blind, Placebo-Controlled, Dose-Escalation, First-In-Human Clinical Study.
Published in:
Dermatology & Therapy, 2023, v. 13, n. 10, p. 2357, doi. 10.1007/s13555-023-01010-1
By:
- Wynne, Christopher John;
- Cole, Alexandra;
- Lemech, Charlotte;
- Wang, Guoqin;
- Zhang, Yu;
- Chen, Benchao;
- Wang, Max;
- Li, Baiyong;
- Xia, Michelle;
- Sinclair, Rodney
Publication type:
Article
The potential for BRAF V600 inhibitors in advanced cutaneous melanoma: rationale and latest evidence.
Published in:
Therapeutic Advances in Medical Oncology, 2012, v. 4, n. 2, p. 61, doi. 10.1177/1758834011432949
By:
- Lemech, Charlotte;
- Infante, Jeffrey;
- Arkenau, Hendrik-Tobias
Publication type:
Article
A first-in-human phase 1 study of nofazinlimab, an anti-PD-1 antibody, in advanced solid tumors and in combination with regorafenib in metastatic colorectal cancer.
Published in:
British Journal of Cancer, 2023, v. 129, n. 10, p. 1608, doi. 10.1038/s41416-023-02431-7
By:
- Day, Daphne;
- Park, John J.;
- Coward, Jermaine;
- Markman, Ben;
- Lemech, Charlotte;
- Kuo, James C.;
- Prawira, Amy;
- Brown, Michael P.;
- Bishnoi, Sarwan;
- Kotasek, Dusan;
- Strother, R. Matthew;
- Cosman, Rasha;
- Su, Rila;
- Ma, Yiding;
- Yue, Zenglian;
- Hu, Hui-han;
- Wu, Rachel;
- Li, Peiqi;
- Tse, Archie N.
Publication type:
Article
Mammographic Breast Density and Urbanization: Interactions with BMI, Environmental, Lifestyle, and Other Patient Factors.
Published in:
Diagnostics (2075-4418), 2020, v. 10, n. 6, p. 418, doi. 10.3390/diagnostics10060418
By:
- Perry, Nick;
- Moss, Sue;
- Dixon, Steve;
- Milner, Sue;
- Mokbel, Kefah;
- Lemech, Charlotte;
- Arkenau, Hendrik-Tobias;
- Duffy, Stephen;
- Pinker, Katja
Publication type:
Article
Novel Treatments for Metastatic Cutaneous Melanoma and the Management of Emergent Toxicities.
Published in:
Clinical Medicine Insights: Oncology, 2012, n. 6, p. 53, doi. 10.4137/CMO.S5855
By:
- Lemech, Charlotte;
- Arkenau, Hendrik-Tobias
Publication type:
Article
Novel Treatments for Metastatic Cutaneous Melanoma and the Management of Emergent Toxicities.
Published in:
Clinical Medicine Insights: Oncology, 2012, n. 6, p. 53, doi. 10.4137/CMO.S5855
By:
- Lemech, Charlotte;
- Arkenau, Hendrik-Tobias
Publication type:
Article
Research biopsies in the context of early phase oncology studies: clinical and ethical considerations.
Published in:
Oncology Reviews, 2013, v. 7, n. 1, p. 34, doi. 10.4081/oncol.2013.e5
By:
- Saggese, Matilde;
- Dua, Divyanshu;
- Simmons, Emily;
- Lemech, Charlotte;
- Arkenau, Hendrik-Tobias
Publication type:
Article
Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer.
Published in:
Oncology, 2016, v. 91, n. 1, p. 48, doi. 10.1159/000445999
By:
- Lemech, Charlotte R.;
- Ensell, Leah;
- Paterson, Jennifer C.;
- Eminowicz, Gemma;
- Lowe, Helen;
- arora, Rupali;
- arkenau, Hendrik-Tobias;
- Widschwendter, Martin;
- MacDonald, Nicola;
- Olaitan, adeola;
- Mould, Tim;
- Meyer, Tim;
- Hartley, John;
- Mitra, anita;
- Ledermann, Jonathan a.;
- McCormack, Mary;
- Kristeleit, Rebecca S.
Publication type:
Article
Patients' Perceptions of Research Biopsies in Phase I Oncology Trials.
Published in:
Oncology, 2015, v. 88, n. 2, p. 95, doi. 10.1159/000368161
By:
- Lemech, Charlotte;
- Dua, Divyanshu;
- Newmark, Joshua;
- Saggese, Matilde;
- Simmons, Emily;
- Spiliopoulou, Paulina;
- Arkenau, Hendrik-Tobias
Publication type:
Article
New South Wales Early Phase Clinical trials Alliance (NECTA): A Model to Improve Efficacy and Access of Early Phase Clinical Trials for Patients and Sponsors.
Published in:
Journal of Immunotherapy & Precision Oncology, 2024, v. 7, n. 3, p. 226, doi. 10.36401/JIPO-24-X2
By:
- Jia Liu;
- Farrow, Max;
- Lemech, Charlotte;
- Mun Hui;
- Underhill, Craig;
- Pal, Abhijit;
- Park, John;
- Nagrial, Adnan;
- Da Silva, Ines;
- Lynam, James;
- Tjokrowidjaja, Angelina;
- Brungs, Daniel;
- Horvath, Lisa;
- Joshua, Anthony
Publication type:
Article
Evaluation of CYP3A-Mediated Drug-Drug Interactions With Romidepsin in Patients With Advanced Cancer.
Published in:
Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1378, doi. 10.1002/jcph.560
By:
- Laille, Eric;
- Patel, Manish;
- Jones, Suzanne F.;
- Burris, Howard A.;
- Infante, Jeffrey;
- Lemech, Charlotte;
- Liu, Liangang;
- Arkenau, Hendrik‐Tobias
Publication type:
Article
A phase Ia study of a novel anti-HER2 antibody–drug conjugate GQ1001 in patients with previously treated HER2 positive advanced solid tumors.
Published in:
Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-024-05985-z
By:
- Zhou, Chenfei;
- Wang, Bin;
- Teng, Christina;
- Yang, Hui;
- Piha-Paul, Sarina A.;
- Richardson, Gary;
- Malalasekera, Ashanya;
- Sun, Yajun;
- Wang, Wei;
- Liu, Jieqiong;
- Shi, Yan;
- Zhan, Xianbao;
- Lemech, Charlotte
Publication type:
Article
Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development.
Published in:
2013
By:
- Jones, Allison;
- Teschendorff, Andrew E;
- Li, Quanxi;
- Hayward, Jane D;
- Kannan, Athilakshmi;
- Mould, Tim;
- West, James;
- Zikan, Michal;
- Cibula, David;
- Fiegl, Heidi;
- Lee, Shih-Han;
- Wik, Elisabeth;
- Hadwin, Richard;
- Arora, Rupali;
- Lemech, Charlotte;
- Turunen, Henna;
- Pakarinen, Päivi;
- Jacobs, Ian J;
- Salvesen, Helga B;
- Bagchi, Milan K
Publication type:
journal article
Role of DNA Methylation and Epigenetic Silencing of <i>HAND2</i> in Endometrial Cancer Development.
Published in:
PLoS Medicine, 2013, v. 10, n. 11, p. 1, doi. 10.1371/journal.pmed.1001551
By:
- Jones, Allison;
- Teschendorff, Andrew E.;
- Li, Quanxi;
- Hayward, Jane D.;
- Kannan, Athilakshmi;
- Mould, Tim;
- West, James;
- Zikan, Michal;
- Cibula, David;
- Fiegl, Heidi;
- Lee, Shih-Han;
- Wik, Elisabeth;
- Hadwin, Richard;
- Arora, Rupali;
- Lemech, Charlotte;
- Turunen, Henna;
- Pakarinen, Päivi;
- Jacobs, Ian J.;
- Salvesen, Helga B.;
- Bagchi, Milan K.
Publication type:
Article
Human papillomavirus (HPV) genotypes in an Australian sample of anal cancers.
Published in:
International Journal of Cancer, 2014, v. 135, n. 4, p. 996, doi. 10.1002/ijc.28730
By:
- Hillman, Richard J.;
- Garland, Suzanne M.;
- Gunathilake, Manoji P.W.;
- Stevens, Matthew;
- Kumaradevan, Nirmala;
- Lemech, Charlotte;
- Ward, Robyn L.;
- Meagher, Alan;
- McHugh, Leo;
- Jin, Fengyi;
- Carroll, Susan;
- Goldstein, David;
- Grulich, Andrew E.;
- Tabrizi, Sepehr N.
Publication type:
Article
Treatment of breast cancer 2 (BRCA2)-mutant follicular dendritic cell sarcoma with a poly ADP-ribose polymerase (PARP) inhibitor: a case report.
Published in:
2016
By:
- Lemech, Charlotte R.;
- Williams, Rachel;
- Thompson, Stephen R.;
- McCaughan, Brian;
- Chin, Melvin
Publication type:
Case Study
Correction to: CXCR2 antagonist navarixin in combination with pembrolizumab in select advanced solid tumors: a phase 2 randomized trial.
Published in:
2024
By:
- Armstrong, Andrew J.;
- Geva, Ravit;
- Chung, Hyun Cheol;
- Lemech, Charlotte;
- Miller Jr, Wilson H.;
- Hansen, Aaron R.;
- Lee, Jong-Seok;
- Tsai, Frank;
- Solomon, Benjamin J.;
- Kim, Tae Min;
- Rolfo, Christian;
- Giranda, Vincent;
- Ren, Yixin;
- Liu, Fang;
- Kandala, Bhargava;
- Freshwater, Tomoko;
- Wang, Judy S.
Publication type:
Correction Notice
CXCR2 antagonist navarixin in combination with pembrolizumab in select advanced solid tumors: a phase 2 randomized trial.
Published in:
Investigational New Drugs, 2024, v. 42, n. 1, p. 145, doi. 10.1007/s10637-023-01410-2
By:
- Armstrong, Andrew J.;
- Geva, Ravit;
- Chung, Hyun Cheol;
- Lemech, Charlotte;
- Miller Jr., Wilson H.;
- Hansen, Aaron R.;
- Lee, Jong-Seok;
- Tsai, Frank;
- Solomon, Benjamin J.;
- Kim, Tae Min;
- Rolfo, Christian;
- Giranda, Vincent;
- Ren, Yixin;
- Liu, Fang;
- Kandala, Bhargava;
- Freshwater, Tomoko;
- Wang, Judy S.
Publication type:
Article
A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors.
Published in:
Investigational New Drugs, 2020, v. 38, n. 6, p. 1815, doi. 10.1007/s10637-020-00960-z
By:
- Lemech, Charlotte;
- Woodward, Natasha;
- Chan, Nancy;
- Mortimer, Joanne;
- Naumovski, Louie;
- Nuthalapati, Silpa;
- Tong, Bo;
- Jiang, Fang;
- Ansell, Peter;
- Ratajczak, Christine K.;
- Sachdev, Jasgit
Publication type:
Article
Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors.
Published in:
2016
By:
- Bendell, Johanna;
- Patel, Manish;
- Yoshida, Kenichiro;
- Seraj, Jabed;
- Weaver, Racquel;
- Lemech, Charlotte;
- Todaro, Thomas;
- Pant, Shubham;
- Arkenau, Hendrik-Tobias;
- Bendell, Johanna C;
- Patel, Manish R;
- Todaro, Thomas G
Publication type:
journal article
Evaluation of intranasal TLR2/6 agonist INNA-051: safety, tolerability and proof of pharmacology.
Published in:
ERJ Open Research, 2024, v. 10, n. 6, p. 1, doi. 10.1183/23120541.00199-2024
By:
- Mercuri, Francesca A.;
- White, Scott;
- McQuilten, Hayley A.;
- Lemech, Charlotte;
- Mynhardt, Stephan;
- Hari, Rana;
- Ping Zhang;
- Kruger, Nicole;
- McLachlan, Grant;
- Miller, Bruce E.;
- West, Nicholas P.;
- Tal-Singer, Ruth;
- Demaison, Christophe
Publication type:
Article
Biomarkers in Advanced Colorectal Cancer: Challenges in Translating Clinical Research into Practice.
Published in:
Cancers, 2011, v. 3, n. 2, p. 1844, doi. 10.3390/cancers3021844
By:
- Lemech, Charlotte;
- Arkenau, Hendrik-Tobias
Publication type:
Article
Approach to the Patient: New Era Emerges for Craniopharyngioma Management.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 11, p. 2986, doi. 10.1210/clinem/dgae503
By:
- Hayes, Annabelle G;
- Jonker, Benjamin;
- Teng, Christina;
- Lemech, Charlotte;
- Killen, Andrew J;
- Sim, Hao-Wen;
- McCormack, Ann I
Publication type:
Article
Erratum to: Development and Evaluation of a New Technological Way of Engaging Patients and Enhancing Understanding of Drug Tolerability in Early Clinical Development: PROACT.
Published in:
2016
By:
- Hughes, Andrew;
- Landers, Donal;
- Arkenau, Hendrik-Tobias;
- Shah, Saj;
- Stephens, Richard;
- Mahal, Amrik;
- Simmons, Matthew;
- Lemech, Charlotte;
- Royle, Jennifer
Publication type:
Erratum
Development and Evaluation of a New Technological Way of Engaging Patients and Enhancing Understanding of Drug Tolerability in Early Clinical Development: PROACT.
Published in:
2016
By:
- Hughes, Andrew;
- Landers, Donal;
- Arkenau, Hendrik-Tobias;
- Shah, Saj;
- Stephens, Richard;
- Mahal, Amrik;
- Simmons, Matthew;
- Lemech, Charlotte;
- Royle, Jennifer
Publication type:
journal article
Combination Molecularly Targeted Drug Therapy in Metastatic Melanoma: Progress to Date.
Published in:
2013
By:
- Lemech, Charlotte;
- Infante, Jeffrey;
- Arkenau, Hendrik-Tobias
Publication type:
Journal Article