Works by Leitner, Judith

Results: 41

FcγR requirements and costimulatory capacity of Urelumab, Utomilumab, and Varlilumab.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1208631

By:

Leitner, Judith;
Egerer, Ricarda;
Waidhofer-Söllner, Petra;
Grabmeier-Pfistershammer, Katharina;
Steinberger, Peter

Publication type:

Article

Cullin-5 deficiency promotes chimeric antigen receptor T cell effector functions potentially via the modulation of JAK/STAT signaling pathway.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54794-x

By:

Adachi, Yoshitaka;
Terakura, Seitaro;
Osaki, Masahide;
Okuno, Yusuke;
Sato, Yoshitaka;
Sagou, Ken;
Takeuchi, Yuki;
Yokota, Hirofumi;
Imai, Kanae;
Steinberger, Peter;
Leitner, Judith;
Hanajiri, Ryo;
Murata, Makoto;
Kiyoi, Hitoshi

Publication type:

Article

LAG‐3—An incompletely understood target in cancer therapy.

Published in:

FASEB Journal, 2024, v. 38, n. 22, p. 1, doi. 10.1096/fj.202401639R

By:

Leitner, Judith;
Aigner‐Radakovics, Katharina;
Steinberger, Peter

Publication type:

Article

A high-throughput two-cell assay for interrogating inhibitory signaling pathways in T cells.

Published in:

Life Science Alliance, 2024, v. 7, n. 3, p. 1, doi. 10.26508/lsa.202302359

By:

Sharma, Sumana;
Whitehead, Toby;
Kotowski, Mateusz;
Zhi Qing Ng, Emily;
Clarke, Joseph;
Leitner, Judith;
Yi-Ling Chen;
Santos, Ana Mafalda;
Steinberger, Peter;
Davis, Simon J.

Publication type:

Article

Single dose granulocyte colony-stimulating factor markedly enhances shear-dependent platelet function in humans.

Published in:

Platelets, 2010, v. 21, n. 6, p. 464, doi. 10.3109/09537104.2010.485255

By:

Spiel, Alexander O.;
Siller-Matula, Jolanta;
Firbas, Christa;
Leitner, Judith M.;
Russmueller, Guenter;
Jilma, Bernd

Publication type:

Article

PD‐1 blocking antibodies moonlighting as killers.

Published in:

European Journal of Immunology, 2021, v. 51, n. 6, p. 1361, doi. 10.1002/eji.202149276

By:

Leitner, Judith;
Battin, Claire;
Grabmeier‐Pfistershammer, Katharina;
Steinberger, Peter

Publication type:

Article

Differentiation and activation of human CD4 T cells is associated with a gradual loss of myelin and lymphocyte protein.

Published in:

European Journal of Immunology, 2021, v. 51, n. 4, p. 848, doi. 10.1002/eji.202048603

By:

Leitner, Judith;
Mahasongkram, Kodchakorn;
Schatzlmaier, Philipp;
Pfisterer, Karin;
Leksa, Vladimir;
Pata, Supansa;
Kasinrerk, Watchara;
Stockinger, Hannes;
Steinberger, Peter

Publication type:

Article

4‐1BB costimulation promotes bystander activation of human CD8 T cells.

Published in:

European Journal of Immunology, 2021, v. 51, n. 3, p. 721, doi. 10.1002/eji.202048762

By:

Reithofer, Manuel;
Rosskopf, Sandra;
Leitner, Judith;
Battin, Claire;
Bohle, Barbara;
Steinberger, Peter;
Jahn‐Schmid, Beatrice

Publication type:

Article

TIM‐3 and CEACAM1 do not interact in cis and in trans.

Published in:

European Journal of Immunology, 2020, v. 50, n. 8, p. 1126, doi. 10.1002/eji.201948400

By:

De Sousa Linhares, Annika;
Kellner, Florian;
Jutz, Sabrina;
Zlabinger, Gerhard J.;
Gabius, Hans‐Joachim;
Huppa, Johannes B.;
Leitner, Judith;
Steinberger, Peter

Publication type:

Article

The soluble cytoplasmic tail of CD45 (ct-CD45) in human plasma contributes to keep T cells in a quiescent state.

Published in:

European Journal of Immunology, 2017, v. 47, n. 1, p. 193, doi. 10.1002/eji.201646405

By:

Puck, Alexander;
Hopf, Stefan;
Modak, Madhura;
Majdic, Otto;
Cejka, Petra;
Blüml, Stephan;
Schmetterer, Klaus;
Arnold‐Schrauf, Catharina;
Gerwien, Jens G.;
Frederiksen, Klaus S.;
Thell, Elisabeth;
Leitner, Judith;
Steinberger, Peter;
Aigner, Regina;
Seyerl‐Jiresch, Maria;
Zlabinger, Gerhard J.;
Stöckl, Johannes

Publication type:

Article

A T‐cell reporter platform for high‐throughput and reliable investigation of TCR function and biology.

Published in:

Clinical & Translational Immunology, 2020, v. 9, n. 11, p. 1, doi. 10.1002/cti2.1216

By:

Müller, Thomas R;
Schuler, Corinna;
Hammel, Monika;
Köhler, Amelie;
Jutz, Sabrina;
Leitner, Judith;
Schober, Kilian;
Busch, Dirk H;
Steinberger, Peter

Publication type:

Article

Immunosuppressive Activity of Artemisia argyi Extract and Isolated Compounds.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00402

By:

Zimmermann-Klemd, Amy M.;
Reinhardt, Jakob K.;
Morath, Anna;
Schamel, Wolfgang W.;
Steinberger, Peter;
Leitner, Judith;
Huber, Roman;
Hamburger, Matthias;
Gründemann, Carsten

Publication type:

Article

Effects of Carbon Monoxide Inhalation during Experimental Endotoxemia in Humans.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2005, v. 171, n. 4, p. 354, doi. 10.1164/rccm.200404-446OC

By:

Mayr, Florian B.;
Spiel, Alexander;
Leitner, Judith;
Marsik, Claudia;
Germann, Peter;
Ullrich, Roman;
Wagner, Oswald;
Jilma, Bernd

Publication type:

Article

Influence of the Duffy genotype on pharmacokinetics and pharmacodynamics of recombinant monocyte chemoattractant protein (MCP-1) in vivo.

Published in:

BMC Pharmacology, 2007, v. 7, p. 1, doi. 10.1186/1471-2210-7-S2-A31

By:

Mayr, Florian B.;
Spiel, Alexander O.;
Leitner, Judith M.;
Firbas, Christa;
Schnee, Janet;
Hilbert, James;
Jilma, Bernd

Publication type:

Article

Pharmacokinetics and pharmacodynamics of the dual FII/FX inhibitor BIBT 986 in endotoxin-induced coagulation.

Published in:

BMC Pharmacology, 2007, v. 7, p. 1, doi. 10.1186/1471-2210-7-S2-A29

By:

Leitner, Judith M.;
Jilma, Bernd;
Mayr, Florian B.;
Cardona, Francesco;
Spiel, Alexander O.;
Firbas, Christa;
Rathgen, Karin;
Stähle, Hildegard;
Schühly, Uwe;
Graefe-Mody, Eva U.

Publication type:

Article

Therapeutic PD-L1 antibodies are more effective than PD-1 antibodies in blocking PD-1/PD-L1 signaling.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47910-1

By:

De Sousa Linhares, Annika;
Battin, Claire;
Jutz, Sabrina;
Leitner, Judith;
Hafner, Christine;
Tobias, Joshua;
Wiedermann, Ursula;
Kundi, Michael;
Zlabinger, Gerhard J.;
Grabmeier-Pfistershammer, Katharina;
Steinberger, Peter

Publication type:

Article

The ligand-dependent suppression of TCR signaling by the immune checkpoint receptor LAG3 depends on the cytoplasmic RRFSALE motif.

Published in:

Science Signaling, 2023, v. 16, n. 805, p. 1, doi. 10.1126/scisignal.adg2610

By:

Aigner-Radakovics, Katharina;
De Sousa Linhares, Annika;
Salzer, Benjamin;
Lehner, Manfred;
Izadi, Shiva;
Castilho, Alexandra;
Pickl, Winfried F.;
Leitner, Judith;
Steinberger, Peter

Publication type:

Article

NKG2A‐checkpoint inhibition and its blockade critically depends on peptides presented by its ligand HLA‐E.

Published in:

Immunology, 2022, v. 166, n. 4, p. 507, doi. 10.1111/imm.13515

By:

Battin, Claire;
Kaufmann, Gabriel;
Leitner, Judith;
Tobias, Joshua;
Wiedermann, Ursula;
Rölle, Alexander;
Meyer, Marten;
Momburg, Frank;
Steinberger, Peter

Publication type:

Article

TIM-3 Does Not Act as a Receptor for Galectin-9.

Published in:

PLoS Pathogens, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.ppat.1003253

By:

Leitner, Judith;
Rieger, Armin;
Pickl, Winfried F.;
Zlabinger, Gerhard;
Grabmeier-Pfistershammer, Katharina;
Steinberger, Peter

Publication type:

Article

Engineered soluble, trimerized 4-1BBL variants as potent immunomodulatory agents.

Published in:

Cancer Immunology, Immunotherapy, 2023, v. 72, n. 9, p. 3029, doi. 10.1007/s00262-023-03474-8

By:

Battin, Claire;
De Sousa Linhares, Annika;
Leitner, Judith;
Grossmann, Anna;
Lupinek, Daniela;
Izadi, Shiva;
Castilho, Alexandra;
Waidhofer-Söllner, Petra;
Grabmeier-Pfistershammer, Katharina;
Stritzker, Jochen;
Steinberger, Peter

Publication type:

Article

Diacylglycerol kinase α inhibition cooperates with PD-1-targeted therapies to restore the T cell activation program.

Published in:

Cancer Immunology, Immunotherapy, 2021, v. 70, n. 11, p. 3277, doi. 10.1007/s00262-021-02924-5

By:

Arranz-Nicolás, Javier;
Martin-Salgado, Miguel;
Adán-Barrientos, Irene;
Liébana, Rosa;
del Carmen Moreno-Ortíz, María;
Leitner, Judith;
Steinberger, Peter;
Ávila-Flores, Antonia;
Merida, Isabel

Publication type:

Article

CTLA-4 antibody ipilimumab negatively affects CD4+ T-cell responses in vitro.

Published in:

Cancer Immunology, Immunotherapy, 2019, v. 68, n. 8, p. 1359, doi. 10.1007/s00262-019-02369-x

By:

Rosskopf, Sandra;
Leitner, Judith;
Zlabinger, Gerhard J.;
Steinberger, Peter

Publication type:

Article

Cyclophilin–CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1460089

By:

Tajti, Gabor;
Gebetsberger, Laura;
Pamlitschka, Gregor;
Aigner-Radakovics, Katharina;
Leitner, Judith;
Steinberger, Peter;
Stockinger, Hannes;
Ohradanova-Repic, Anna

Publication type:

Article

Ig-like transcript 4 as a cellular receptor for soluble complement fragment C4d.

Published in:

FASEB Journal, 2016, v. 30, n. 4, p. 1492, doi. 10.1096/fj.15-275594

By:

Hofer, Johannes;
Forster, Florian;
Isenman, David E.;
Wahrmann, Markus;
Leitner, Judith;
Hölzl, Markus A.;
Kovarik, Johannes J.;
Stockinger, Hannes;
Böhmig, Georg A.;
Steinberger, Peter;
Zlabinger, Gerhard J.

Publication type:

Article

STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4+ T cells.

Published in:

FASEB Journal, 2015, v. 29, n. 3, p. 759, doi. 10.1096/fj.14-257584

By:

Schmetterer, Klaus G.;
Neunkirchner, Alina;
Wojta-Stremayr, Daniela;
Leitner, Judith;
Steinberger, Peter;
Pickl, Winfried F.

Publication type:

Article

HLA-E/peptide complexes differentially interact with NKG2A/CD94 and T cell receptors.

Published in:

Journal of Immunology, 2025, v. 214, n. 4, p. 595, doi. 10.1093/jimmun/vkae068

By:

Voogd, Linda;
van den Broek, Remco L;
van Wolfswinkel, Marjolein;
Franken, Kees L M C;
Ruibal, Paula;
Jespers, Willem;
Leitner, Judith;
Steinberger, Peter;
van Westen, Gerard J P;
Ottenhoff, Tom H M;
Joosten, Simone A

Publication type:

Article

Interoperability of RTN1A in dendrite dynamics and immune functions in human Langerhans cells.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.80578

By:

Cichoń, Małgorzata Anna;
Pfisterer, Karin;
Leitner, Judith;
Wagner, Lena;
Staud, Clement;
Steinberger, Peter;
Elbe-Bürger, Adelheid

Publication type:

Article

Plant‐derived Durvalumab variants show efficient PD‐1/PD‐L1 blockade and therapeutically favourable FcR binding.

Published in:

Plant Biotechnology Journal, 2024, v. 22, n. 5, p. 1224, doi. 10.1111/pbi.14260

By:

Izadi, Shiva;
Gumpelmair, Simon;
Coelho, Pedro;
Duarte, Henrique O.;
Gomes, Joana;
Leitner, Judith;
Kunnummel, Vinny;
Mach, Lukas;
Reis, Celso A.;
Steinberger, Peter;
Castilho, Alexandra

Publication type:

Article

PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells.

Published in:

Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00572

By:

Stecher, Carmen;
Battin, Claire;
Leitner, Judith;
Zettl, Markus;
Grabmeier-Pfistershammer, Katharina;
Höller, Christoph;
Zlabinger, Gerhard J.;
Steinberger, Peter

Publication type:

Article

Recombinant human antithrombin inhibits thrombin formation and interleukin 6 release in human endotoxemia*.

Published in:

Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 1, p. 23, doi. 10.1016/j.clpt.2005.10.003

By:

Leitner, Judith M.;
Firbas, Christa;
Mayr, Florian B.;
Reiter, Rosemarie A.;
Steinlechner, Barbara;
Jilma, Bernd

Publication type:

Article

Neuropilin-1 Acts as a Receptor for Complement Split Products.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02209

By:

Battin, Claire;
De Sousa Linhares, Annika;
Paster, Wolfgang;
Isenman, David E.;
Wahrmann, Markus;
Leitner, Judith;
Zlabinger, Gerhard J.;
Steinberger, Peter;
Hofer, Johannes

Publication type:

Article

Overexpression of PDE4A Acts as Checkpoint Inhibitor Against cAMP-Mediated Immunosuppression in vitro.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01790

By:

Schmetterer, Klaus G.;
Goldhahn, Katrin;
Ziegler, Liesa S.;
Gerner, Marlene C.;
Schmidt, Ralf L. J.;
Themanns, Madeleine;
Zebedin-Brandl, Eva;
Trapin, Doris;
Leitner, Judith;
Pickl, Winfried F.;
Steinberger, Peter;
Schwarzinger, Ilse;
Marculescu, Rodrig

Publication type:

Article

Development of a Human Cytomegalovirus (HCMV)-Based Therapeutic Cancer Vaccine Uncovers a Previously Unsuspected Viral Block of MHC Class I Antigen Presentation.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01776

By:

Abdelaziz, Mohammed O.;
Ossmann, Sophia;
Kaufmann, Andreas M.;
Leitner, Judith;
Steinberger, Peter;
Willimsky, Gerald;
Raftery, Martin J.;
Schönrich, Günther

Publication type:

Article

Researcher of the Month Oktober 2013.

Published in:

Wiener Klinische Wochenschrift, 2013, v. 125, n. 19/20, p. 637, doi. 10.1007/s00508-013-0442-z

By:

Leitner, Judith

Publication type:

Article

Multiple-dose pharmacokinetics of anidulafungin during continuous venovenous haemoﬁltration.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2011, v. 66, n. 4, p. 880, doi. 10.1093/jac/dkq545

By:

Leitner, Judith M.;
Meyer, Brigitte;
Fuhrmann, Valentin;
Saria, Katrin;
Zuba, Clara;
Jäger, Walter;
Böhmdorfer, Michaela;
Thalhammer, Florian

Publication type:

Article

Discovery of the first PD-1 ligand encoded by a pathogen.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1007334

By:

Martínez-Vicente, Pablo;
Poblador, Francesc;
Leitner, Judith;
Farré, Domènec;
Steinberger, Peter;
Engel, Pablo;
Angulo, Ana

Publication type:

Article

BTLA inhibition has a dominant role in the cis-complex of BTLA and HVEM.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.956694

By:

Battin, Claire;
Leitner, Judith;
Waidhofer-Söllner, Petra;
Grabmeier-Pfistershammer, Katharina;
Olive, Daniel;
Steinberger, Peter

Publication type:

Article

A Highly Sensitive Cell-Based TLR Reporter Platform for the Specific Detection of Bacterial TLR Ligands.

Published in:

Frontiers in Immunology, 2022, v. 12, p. 1, doi. 10.3389/fimmu.2021.817604

By:

Radakovics, Katharina;
Battin, Claire;
Leitner, Judith;
Geiselhart, Sabine;
Paster, Wolfgang;
Stöckl, Johannes;
Hoffmann-Sommergruber, Karin;
Steinberger, Peter

Publication type:

Article

B7-H3 is a potent inhibitor of human T-cell activation: No evidence for B7-H3 and TREML2 interaction.

Published in:

European Journal of Immunology, 2009, v. 39, n. 7, p. 1754, doi. 10.1002/eji.200839028

By:

Leitner, Judith;
Klauser, Christoph;
Pickl, Winfried F.;
Stöckl, Johannes;
Majdic, Otto;
Bardet, Anaïs F.;
Kreil, David P.;
Dong, Chen;
Yamazaki, Tomohide;
Zlabinger, Gerhard;
Pfistershammer, Katharina;
Steinberger, Peter

Publication type:

Article

The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells.

Published in:

European Journal of Immunology, 2008, v. 38, n. 10, p. 2678, doi. 10.1002/eji.200838250

By:

Kober, Johanna;
Leitner, Judith;
Klauser, Christoph;
Woitek, Ramona;
Majdic, Otto;
Stöckl, Johannes;
Herndler-Brandstetter, Dietmar;
Grubeck-Loebenstein, Beatrix;
Reipert, Birgit M.;
Pickl, Winfried F.;
Pfistershammer, Katharina;
Steinberger, Peter

Publication type:

Article

No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation.

Published in:

European Journal of Immunology, 2006, v. 36, n. 5, p. 1104, doi. 10.1002/eji.200535344

By:

Pfistershammer, Katharina;
Klauser, Christoph;
Pickl, Winfried F.;
Stöckl, Johannes;
Leitner, Judith;
Zlabinger, Gerhard;
Majdic, Otto;
Steinberger, Peter

Publication type:

Article