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mt-Nd2Allele of the ALR/Lt mouse confers resistance against both chemically induced and autoimmune diabetes.
Published in:
Diabetologia, 2005, v. 48, n. 2, p. 261, doi. 10.1007/s00125-004-1644-8
By:
- Mathews, C. E.;
- Gusdon, A. M.;
- Ringquist, S.;
- Leiter, E. H.;
- Spirina, O.;
- Bykhovskaya, Y.;
- Fischel-Ghodsian, N.
Publication type:
Article
Animal models have little to teach us about Type 1 diabetes: 2. In opposition to this proposal.
Published in:
Diabetologia, 2004, v. 47, n. 10, p. 1657, doi. 10.1007/s00125-004-1518-0
By:
- Leiter, E. H.;
- Von Herrath, M.
Publication type:
Article
Mice with targeted gene disruptions or gene insertions for diabetes research: problems, pitfalls, and potential solutions.
Published in:
Diabetologia, 2002, v. 45, n. 3, p. 296, doi. 10.1007/s00125-001-0743-z
By:
- Leiter, E. H.
Publication type:
Article
Unexpected functional consequences of xenogeneic transgene expression in β-cells of NOD mice.
Published in:
Diabetes, Obesity & Metabolism, 2007, v. 9, p. 14, doi. 10.1111/j.1463-1326.2007.00770.x
By:
- Leiter, E. H.;
- Reifsnyder, P.;
- Driver, J.;
- Kamdar, S.;
- Choisy-Rossi, C.;
- Serreze, D. V.;
- Hara, M.;
- Chervonsky, A.
Publication type:
Article
Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease.
Published in:
Genes & Immunity, 2010, v. 11, n. 3, p. 219, doi. 10.1038/gene.2010.4
By:
- Jurisic, G.;
- Sundberg, J. P.;
- Bleich, A.;
- Leiter, E. H.;
- Broman, K. W.;
- Buechler, G.;
- Alley, L.;
- Vestweber, D.;
- Detmar, M.
Publication type:
Article
Conditioning the genome identifies additional diabetes resistance loci in Type 1 diabetes-resistant NOR/Lt mice.
Published in:
2006
By:
- Reifsnyder, P. C.;
- Li, R.;
- Silveira, P. A.;
- Churchill, G.;
- Serreze, D. V.;
- Leiter, E. H.
Publication type:
Correction Notice
Conditioning the genome identifies additional diabetes resistance loci in Type I diabetes resistant NOR/Lt mice.
Published in:
Genes & Immunity, 2005, v. 6, n. 6, p. 528, doi. 10.1038/sj.gene.6364241
By:
- Reifsnyder, P. C.;
- Li, R.;
- Silveira, P. A.;
- Churchill, G.;
- Serreze, D. V.;
- Leiter, E. H.
Publication type:
Article
Estrone treatment dissociates primary versus secondary consequences of "diabetes" (db) gene expression in mice.
Published in:
1986
By:
- Prochazka, Michal;
- Premdas, Francis H.;
- Leiter, Edward H.;
- Lipson, Loren G.;
- Prochazka, M;
- Premdas, F H;
- Leiter, E H;
- Lipson, L G
Publication type:
journal article
Genetic control of pathogenesis of diabetes in C3H mice. Influence of the major histocompatibility complex.
Published in:
1984
By:
- Leiter, Edward H.;
- Leiter, E H
Publication type:
journal article
Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice.
Published in:
1984
By:
- Coleman, D. L.;
- Schwizer, R. W.;
- Leiter, E. H.
Publication type:
journal article
The effect of immunosuppression on streptozotocin-induced diabetes in C57BL/KsJ mice.
Published in:
1983
By:
- Leiter, Edward H.;
- Beamer, W. G.;
- Shultz, L. D.;
- Leiter, E H
Publication type:
journal article
Therapeutic effects of dehydroepiandrosterone (DHEA) in diabetic mice.
Published in:
1982
By:
- Coleman, D. L.;
- Leiter, E. H.;
- Schwizer, R. W.
Publication type:
journal article
The influence of genetic background on the expression of mutations at the diabetes locus in the mouse IV. Male lethal syndrome in CBA/Lt mice.
Published in:
1981
By:
- Leiter, Edward H.;
- Leiter, E H
Publication type:
journal article
The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex.
Published in:
1981
By:
- Leiter, Edward H.;
- Coleman, Douglas L.;
- Hummel, Katharine P.;
- Leiter, E H;
- Coleman, D L;
- Hummel, K P
Publication type:
journal article
Induction in C57BL/KsJ mice of complement-dependent antibody cytotoxic to cultured beta cells.
Published in:
1981
By:
- Leiter, Edward H.;
- Simon, Douglas;
- Cherry, Marianna;
- Phillips, Catherine A.;
- Leiter, E H;
- Simon, D;
- Cherry, M;
- Phillips, C A
Publication type:
journal article
Experimental Models to Study Molecular Mechanisms Underlying Intestinal Inflammation.
Published in:
Annals of the New York Academy of Sciences, 1998, v. 859, n. 1, p. 85, doi. 10.1111/j.1749-6632.1998.tb11113.x
By:
- ELSON, C. O.;
- CONG, Y.;
- BRANDWEIN, S.;
- WEAVER, C. T.;
- McCABE, R. P.;
- MÄHLER, M.;
- SUNDBERG, J. P.;
- LEITER, E. H.
Publication type:
Article
Reevaluation of the major histocompatibility complex genes of the NOD-progenitor CTS/Shi strain.
Published in:
2000
By:
- Mathews, Clayton E.;
- Graser, Robert T.;
- Serreze, David V.;
- Leiter, Edward H.;
- Mathews, C E;
- Graser, R T;
- Serreze, D V;
- Leiter, E H
Publication type:
journal article
Resistance of ALR/Lt islets to free radical-mediated diabetogenic stress is inherited as a dominant trait.
Published in:
1999
By:
- Mathews, Clayton E.;
- Leiter, Edward H.;
- Mathews, C E;
- Leiter, E H
Publication type:
journal article
Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene.
Published in:
1999
By:
- Ebert, Daniel H.;
- Bischof, Larry J.;
- Streeper, Ryan S.;
- Chapman, Stacey C.;
- Svitek, Christina A.;
- Goldman, Joshua K.;
- Mathews, Clayton E.;
- Loiter, Edward H.;
- Hutton, John C.;
- O'Brien, Richard M.;
- Ebert, D H;
- Bischof, L J;
- Streeper, R S;
- Chapman, S C;
- Svitek, C A;
- Goldman, J K;
- Mathews, C E;
- Leiter, E H;
- Hutton, J C;
- O'Brien, R M
Publication type:
journal article
Differential protection in two transgenic lines of NOD/Lt mice hyperexpressing the autoantigen GAD65 in pancreatic beta-cells.
Published in:
1998
By:
- Bridgett, Margot;
- Cetkovic-Cvrlje, Marina;
- O'Rourke, Robert;
- Yuguang Shi;
- Narayanswami, Sandya;
- Lambert, Jeremy;
- Ramiya, Vijayakumar;
- Baekkeskov, Steinunn;
- Leiter, Edward H.;
- Bridgett, M;
- Cetkovic-Cvrlje, M;
- O'Rourke, R;
- Shi, Y;
- Narayanswami, S;
- Lambert, J;
- Ramiya, V;
- Baekkeskov, S;
- Leiter, E H
Publication type:
journal article
NIDDM genes in mice: deleterious synergism by both parental genomes contributes to diabetogenic thresholds.
Published in:
1998
By:
- Leiter, E H;
- Reifsnyder, P C;
- Flurkey, K;
- Partke, H J;
- Junger, E;
- Herberg, L
Publication type:
journal article
Retardation or acceleration of diabetes in NOD/Lt mice mediated by intrathymic administration of candidate beta-cell antigens.
Published in:
1997
By:
- Cetkovic-Cvrlje, Marina;
- Gerling, Ivan C.;
- Muir, Andrew;
- Atkinson, Mark A.;
- Elliott, John F.;
- Leiter, Edward H.;
- Cetkovic-Cvrlje, M;
- Gerling, I C;
- Muir, A;
- Atkinson, M A;
- Elliott, J F;
- Leiter, E H
Publication type:
journal article
MHC class I-mediated antigen presentation and induction of CD8+ cytotoxic T-cell responses in autoimmune diabetes-prone NOD mice.
Published in:
1996
By:
- Serreze, David V.;
- Gallichan, W. Scott;
- Snider, Denis P.;
- Croitoru, Kenneth;
- Rosenthal, Kenneth L.;
- Leiter, Edward H.;
- Christianson, Gregory J.;
- Dudley, Mark E.;
- Roopenian, Derry C.;
- Serreze, D V;
- Gallichan, W S;
- Snider, D P;
- Croitoru, K;
- Rosenthal, K L;
- Leiter, E H;
- Christianson, G J;
- Dudley, M E;
- Roopenian, D C
Publication type:
journal article
Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells.
Published in:
1995
By:
- Serreze, David V.;
- Leiter, Edward H.;
- Hanson, Matthew S.;
- Christianson, Sherri W.;
- Shultz, Leonard D.;
- Hesselton, RuthAnn M.;
- Greiner, Dale L.;
- Serreze, D V;
- Leiter, E H;
- Hanson, M S;
- Christianson, S W;
- Shultz, L D;
- Hesselton, R M;
- Greiner, D L
Publication type:
journal article
Dexamethasone-induced hyperglycemia in obese Avy/a (viable yellow) female mice entails preferential induction of a hepatic estrogen sulfotransferase.
Published in:
1994
By:
- Gill, Anne M.;
- Leiter, Edward H.;
- Powell, Jerry G.;
- Chapman, Harry D.;
- Yen, Terence T.;
- Gill, A M;
- Leiter, E H;
- Powell, J G;
- Chapman, H D;
- Yen, T T
Publication type:
journal article
Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes.
Published in:
1994
By:
- Wicker, L S;
- Leiter, E H;
- Todd, J A;
- Renjilian, R J;
- Peterson, E;
- Fischer, P A;
- Podolin, P L;
- Zijlstra, M;
- Jaenisch, R;
- Peterson, L B
Publication type:
journal article
Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant.
Published in:
1994
By:
- Serreze, David V.;
- Leiter, Edward H.;
- Christianson, Gregory J.;
- Greiner, Dale;
- Roopenian, Derry C.;
- Serreze, D V;
- Leiter, E H;
- Christianson, G J;
- Greiner, D;
- Roopenian, D C
Publication type:
journal article
Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes.
Published in:
1994
By:
- Gerling, Ivan C.;
- Friedman, Harley;
- Greiner, Dale L.;
- Shultz, Leonard D.;
- Leiter, Edward H.;
- Gerling, I C;
- Friedman, H;
- Greiner, D L;
- Shultz, L D;
- Leiter, E H
Publication type:
journal article
Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors.
Published in:
1993
By:
- Christianson, Sherri W.;
- Shultz, Leonard D.;
- Leiter, Edward H.;
- Christianson, S W;
- Shultz, L D;
- Leiter, E H
Publication type:
journal article
Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice.
Published in:
1992
By:
- Gerling, I C;
- Serreze, D V;
- Christianson, S W;
- Leiter, E H
Publication type:
journal article
NOR/Lt mice: MHC-matched diabetes-resistant control strain for NOD mice.
Published in:
1992
By:
- Prochazka, Michal;
- Serreze, David V.;
- Frankel, Wayne N.;
- Leiter, Edward H.;
- Prochazka, M;
- Serreze, D V;
- Frankel, W N;
- Leiter, E H
Publication type:
journal article
Synergism of obesity genes with hepatic steroid sulfotransferases to mediate diabetes in mice.
Published in:
1991
By:
- Leiter, Edward H.;
- Chapman, Harold D.;
- Falany, Charles N.;
- Leiter, E H;
- Chapman, H D;
- Falany, C N
Publication type:
journal article
NIT-1, a pancreatic beta-cell line established from a transgenic NOD/Lt mouse.
Published in:
1991
By:
- Hamaguchi, K;
- Gaskins, H R;
- Leiter, E H
Publication type:
journal article
Effect of diet on incidence of diabetes in nonobese diabetic mice.
Published in:
1990
By:
- Coleman, Douglas L.;
- Kuzava, Joan E.;
- Leiter, Edward H.;
- Coleman, D L;
- Kuzava, J E;
- Leiter, E H
Publication type:
journal article
Comparison of cytokine effects on mouse pancreatic alpha-cell and beta-cell lines. Viability, secretory function, and MHC antigen expression.
Published in:
1990
By:
- Hamaguchi, K;
- Leiter, E H
Publication type:
journal article
Genetic control of diabetogenesis in NOD/Lt mice. Development and analysis of congenic stocks.
Published in:
1989
By:
- Prochazka, Michal;
- Serreze, David V.;
- Worthen, Sherri M.;
- Leiter, Edward H.;
- Prochazka, M;
- Serreze, D V;
- Worthen, S M;
- Leiter, E H
Publication type:
journal article
Molecular mimicry between insulin and retroviral antigen p73. Development of cross-reactive autoantibodies in sera of NOD and C57BL/KsJ db/db mice.
Published in:
1988
By:
- Serreze, David V.;
- Leiter, Edward H.;
- Kuff, Edward L.;
- Jardieu, Paula;
- Ishizaka, Kimishige;
- Serreze, D V;
- Leiter, E H;
- Kuff, E L;
- Jardieu, P;
- Ishizaka, K
Publication type:
journal article
NOD marrow stem cells adoptively transfer diabetes to resistant (NOD x NON)F1 mice.
Published in:
1988
By:
- Serreze, David V.;
- Leiter, Edward H.;
- Worthen, Sherri M.;
- Shultz, Leonard D.;
- Serreze, D V;
- Leiter, E H;
- Worthen, S M;
- Shultz, L D
Publication type:
journal article

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