Works by Leitans, Janis

Results: 8

3 H -1,2-benzoxathiepine 2,2-dioxides: a new class of isoform-selective carbonic anhydrase inhibitors.
Published in:
Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 767, doi. 10.1080/14756366.2017.1316720
By:
- Pustenko, Aleksandrs;
- Stepanovs, Dmitrijs;
- Žalubovskis, Raivis;
- Vullo, Daniela;
- Kazaks, Andris;
- Leitans, Janis;
- Tars, Kaspars;
- Supuran, Claudiu T.
Publication type:
Article
Front Cover: Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX (ChemMedChem 22/2023).
Published in:
ChemMedChem, 2023, v. 18, n. 22, p. 1, doi. 10.1002/cmdc.202300639
By:
- Leitans, Janis;
- Kazaks, Andris;
- Bogans, Janis;
- Supuran, Claudiu T.;
- Akopjana, Inara;
- Ivanova, Jekaterina;
- Zalubovskis, Raivis;
- Tars, Kaspars
Publication type:
Article
Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX.
Published in:
ChemMedChem, 2023, v. 18, n. 22, p. 1, doi. 10.1002/cmdc.202300454
By:
- Leitans, Janis;
- Kazaks, Andris;
- Bogans, Janis;
- Supuran, Claudiu T.;
- Akopjana, Inara;
- Ivanova, Jekaterina;
- Zalubovskis, Raivis;
- Tars, Kaspars
Publication type:
Article
Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 130, doi. 10.3390/ijms23010130
By:
- Zakšauskas, Audrius;
- Čapkauskaitė, Edita;
- Paketurytė-Latvė, Vaida;
- Smirnov, Alexey;
- Leitans, Janis;
- Kazaks, Andris;
- Dvinskis, Elviss;
- Stančaitis, Laimonas;
- Mickevičiūtė, Aurelija;
- Jachno, Jelena;
- Jezepčikas, Linas;
- Linkuvienė, Vaida;
- Sakalauskas, Andrius;
- Manakova, Elena;
- Gražulis, Saulius;
- Matulienė, Jurgita;
- Tars, Kaspars;
- Matulis, Daumantas
Publication type:
Article
Aryl-4,5-dihydro-1H-pyrazole-1-carboxamide Derivatives Bearing a Sulfonamide Moiety Show Single-digit Nanomolar-to-Subnanomolar Inhibition Constants against the Tumor-associated Human Carbonic Anhydrases IX and XII.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2621, doi. 10.3390/ijms21072621
By:
- Hargunani, Priya;
- Tadge, Nikhil;
- Ceruso, Mariangela;
- Leitans, Janis;
- Kazaks, Andris;
- Tars, Kaspars;
- Gratteri, Paola;
- Supuran, Claudiu T.;
- Nocentini, Alessio;
- Toraskar, Mrunmayee P.
Publication type:
Article
Extending the Inhibition Profiles of Coumarin-Based Compounds Against Human Carbonic Anhydrases: Synthesis, Biological, and In Silico Evaluation.
Published in:
Molecules, 2019, v. 24, n. 19, p. 3580, doi. 10.3390/molecules24193580
By:
- Kartsev, Victor;
- Geronikaki, Athina;
- Bua, Silvia;
- Nocentini, Alessio;
- Petrou, Anthi;
- Lichitsky, Boris;
- Frasinyuk, Mykhaylo;
- Leitans, Janis;
- Kazaks, Andris;
- Tars, Kaspars;
- Supuran, Claudiu T.
Publication type:
Article
Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.101401
By:
- Vaškevičius, Aivaras;
- Baronas, Denis;
- Leitans, Janis;
- Kvietkauskaitė, Agnė;
- Rukšėnaitė, Audronė;
- Manakova, Elena;
- Toleikis, Zigmantas;
- Kaupinis, Algirdas;
- Kazaks, Andris;
- Gedgaudas, Marius;
- Mickevičiūtė, Aurelija;
- Juozapaitienė, Vaida;
- Schiöth, Helgi B.;
- Jaudzems, Kristaps;
- Valius, Mindaugas;
- Tars, Kaspars;
- Gražulis, Saulius;
- Meyer-Almes, Franz-Josef;
- Matulienė, Jurgita;
- Zubrienė, Asta
Publication type:
Article
Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.
Published in:
Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 12, p. 1531, doi. 10.1107/S2053230X15022049
By:
- Recacha, Rosario;
- Leitans, Janis;
- Akopjana, Inara;
- Aprupe, Lilija;
- Trapencieris, Peteris;
- Jaudzems, Kristaps;
- Jirgensons, Aigars;
- Tars, Kaspars
Publication type:
Article