Works by Leif Groop


Results: 324
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    Urinary extracellular vesicles: Assessment of pre‐analytical variables and development of a quality control with focus on transcriptomic biomarker research.

    Published in:
    Journal of Extracellular Vesicles, 2021, v. 10, n. 12, p. 1, doi. 10.1002/jev2.12158
    By:
    • Barreiro, Karina;
    • Dwivedi, Om Prakash;
    • Valkonen, Sami;
    • Groop, Per‐Henrik;
    • Tuomi, Tiinamaija;
    • Holthofer, Harry;
    • Rannikko, Antti;
    • Yliperttula, Marjo;
    • Siljander, Pia;
    • Laitinen, Saara;
    • Serkkola, Elina;
    • af Hällström, Taija;
    • Forsblom, Carol;
    • Groop, Leif;
    • Puhka, Maija
    Publication type:
    Article
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    Absence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Should Lead to Testing for MODY: Lessons From a 5-Year Pediatric Swedish National Cohort Study.

    Published in:
    Diabetes Care, 2020, v. 43, n. 1, p. 82, doi. 10.2337/dc19-0747
    By:
    • Carlsson, Annelie;
    • Shepherd, Maggie;
    • Ellard, Sian;
    • Weedon, Michael;
    • Lernmark, Åke;
    • Forsander, Gun;
    • Colclough, Kevin;
    • Brahimi, Qefsere;
    • Valtonen-Andre, Camilla;
    • Ivarsson, Sten A.;
    • Larsson, Helena Elding;
    • Samuelsson, Ulf;
    • Örtqvist, Eva;
    • Groop, Leif;
    • Ludvigsson, Johnny;
    • Marcus, Claude;
    • Hattersley, Andrew T.
    Publication type:
    Article
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    Age at menopause, reproductive life span, and type 2 diabetes risk: results from the EPIC-InterAct study.

    Published in:
    2013
    By:
    • Brand, Judith S;
    • van der Schouw, Yvonne T;
    • Onland-Moret, N Charlotte;
    • Sharp, Stephen J;
    • Ong, Ken K;
    • Khaw, Kay-Tee;
    • Ardanaz, Eva;
    • Amiano, Pilar;
    • Boeing, Heiner;
    • Chirlaque, Maria-Dolores;
    • Clavel-Chapelon, Françoise;
    • Crowe, Francesca L;
    • de Lauzon-Guillain, Blandine;
    • Duell, Eric J;
    • Fagherazzi, Guy;
    • Franks, Paul W;
    • Grioni, Sara;
    • Groop, Leif C;
    • Kaaks, Rudolf;
    • Key, Timothy J
    Publication type:
    journal article
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    Age at Menopause, Reproductive Life Span, and Type 2 Diabetes Risk.

    Published in:
    Diabetes Care, 2013, v. 36, n. 4, p. 1012, doi. 10.2337/dc12-1020
    By:
    • BRAND, JUDITH S.;
    • VAN DER SCHOUW, YVONNE T.;
    • ONLAND-MORET, N. CHARLOTTE;
    • SHARP, STEPHEN J.;
    • ONG, KEN K.;
    • KHAW, KAY-TEE;
    • ARDANAZ, EVA;
    • AMIANO, PILAR;
    • BOEING, HEINER;
    • CHIRLAQUE, MARIA-DOLORES;
    • CLAVEL-CHAPELON, FRANÇOISE;
    • CROWE, FRANCESCA L.;
    • DE LAUZON-GUILLAIN, BLANDINE;
    • DUELL, ERIC J.;
    • FAGHERAZZI, GUY;
    • FRANKS, PAUL W.;
    • GRIONI, SARA;
    • GROOP, LEIF C.;
    • KAAKS, RUDOLF;
    • KEY, TIMOTHY J.
    Publication type:
    Article
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    Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study.

    Published in:
    PLoS Medicine, 2014, v. 11, n. 5, p. 1, doi. 10.1371/journal.pmed.1001647
    By:
    • Langenberg, Claudia;
    • Sharp, Stephen J.;
    • Franks, Paul W.;
    • Scott, Robert A.;
    • Deloukas, Panos;
    • Forouhi, Nita G.;
    • Froguel, Philippe;
    • Groop, Leif C.;
    • Hansen, Torben;
    • Palla, Luigi;
    • Pedersen, Oluf;
    • Schulze, Matthias B.;
    • Tormo, Maria-Jose;
    • Wheeler, Eleanor;
    • Agnoli, Claudia;
    • Arriola, Larraitz;
    • Barricarte, Aurelio;
    • Boeing, Heiner;
    • Clarke, Geraldine M.;
    • Clavel-Chapelon, Françoise
    Publication type:
    Article
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    TXNIP regulates peripheral glucose metabolism in humans.

    Published in:
    2007
    By:
    • Parikh, Hemang;
    • Carlsson, Emma;
    • Chutkow, William A.;
    • Johansson, Lovisa E.;
    • Storgaard, Heidi;
    • Poulsen, Pernille;
    • Saxena, Richa;
    • Ladd, Christine;
    • Schulze, P. Christian;
    • Mazzini, Michael J.;
    • Jensen, Christine Bjørn;
    • Krook, Anna;
    • Björnholm, Marie;
    • Tornqvist, Hans;
    • Zierath, Juleen R.;
    • Ridderstråle, Martin;
    • Altshuler, David;
    • Lee, Richard T.;
    • Vaag, Allan;
    • Groop, Leif C.
    Publication type:
    journal article
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    Genetic Prediction of Future Type 2 Diabetes.

    Published in:
    PLoS Medicine, 2005, v. 2, n. 12, p. e345, doi. 10.1371/journal.pmed.0020345
    By:
    • Lyssenko, Valeriya;
    • Almgren, Peter;
    • Anevski, Dragi;
    • Orho-Melander, Marju;
    • Sjögren, Marketa;
    • Saloranta, Carola;
    • Tuomi, Tiinamaija;
    • Groop, Leif
    Publication type:
    Article
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    Genetic factors affect the susceptibility to bacterial infections in diabetes.

    Published in:
    Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88273-w
    By:
    • Simonsen, Johan R.;
    • Käräjämäki, Annemari;
    • Antikainen, Anni A.;
    • Toppila, Iiro;
    • Ahlqvist, Emma;
    • Prasad, Rashmi;
    • Mansour-Aly, Dina;
    • Harjutsalo, Valma;
    • Järvinen, Asko;
    • Tuomi, Tiinamaija;
    • Groop, Leif;
    • Forsblom, Carol;
    • Groop, Per-Henrik;
    • Sandholm, Niina;
    • Lehto, Markku
    Publication type:
    Article
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    Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes.

    Published in:
    Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68130-y
    By:
    • Jain, Ruchi;
    • Özgümüş, Türküler;
    • Jensen, Troels Mygind;
    • du Plessis, Elsa;
    • Keindl, Magdalena;
    • Møller, Cathrine Laustrup;
    • Falhammar, Henrik;
    • Nyström, Thomas;
    • Catrina, Sergiu-Bogdan;
    • Jörneskog, Gun;
    • Jessen, Leon Eyrich;
    • Forsblom, Carol;
    • Haukka, Jani K.;
    • Groop, Per-Henrik;
    • Rossing, Peter;
    • Groop, Leif;
    • Eliasson, Mats;
    • Eliasson, Björn;
    • Brismar, Kerstin;
    • Al-Majdoub, Mahmoud
    Publication type:
    Article
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    Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance.

    Published in:
    Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00895-9
    By:
    • Patel, Kashyap A.;
    • Kettunen, Jarno;
    • Laakso, Markku;
    • Stančáková, Alena;
    • Laver, Thomas W.;
    • Colclough, Kevin;
    • Johnson, Matthew B.;
    • Abramowicz, Marc;
    • Groop, Leif;
    • Miettinen, Päivi J.;
    • Shepherd, Maggie H.;
    • Flanagan, Sarah E.;
    • Ellard, Sian;
    • Nobuya Inagaki;
    • Hattersley, Andrew T.;
    • Tiinamaija Tuomi;
    • Cnop, Miriam;
    • Weedon, Michael N.
    Publication type:
    Article
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    Desmoglein-2 is important for islet function and β-cell survival.

    Published in:
    Cell Death & Disease, 2022, v. 13, n. 10, p. 1, doi. 10.1038/s41419-022-05326-2
    By:
    • Myo Min, Kay K.;
    • Rojas-Canales, Darling;
    • Penko, Daniella;
    • DeNichilo, Mark;
    • Cockshell, Michaelia P.;
    • Ffrench, Charlie B.;
    • Thompson, Emma J.;
    • Asplund, Olof;
    • Drogemuller, Christopher J.;
    • Prasad, Rashmi B.;
    • Groop, Leif;
    • Grey, Shane T.;
    • Thomas, Helen E.;
    • Loudovaris, Thomas;
    • Kay, Thomas W.;
    • Mahoney, My G.;
    • Jessup, Claire F.;
    • Coates, P. Toby;
    • Bonder, Claudine S.
    Publication type:
    Article
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    Desmoglein-2 is important for islet function and β-cell survival.

    Published in:
    Cell Death & Disease, 2022, v. 13, n. 10, p. 1, doi. 10.1038/s41419-022-05326-2
    By:
    • Myo Min, Kay K.;
    • Rojas-Canales, Darling;
    • Penko, Daniella;
    • DeNichilo, Mark;
    • Cockshell, Michaelia P.;
    • Ffrench, Charlie B.;
    • Thompson, Emma J.;
    • Asplund, Olof;
    • Drogemuller, Christopher J.;
    • Prasad, Rashmi B.;
    • Groop, Leif;
    • Grey, Shane T.;
    • Thomas, Helen E.;
    • Loudovaris, Thomas;
    • Kay, Thomas W.;
    • Mahoney, My G.;
    • Jessup, Claire F.;
    • Coates, P. Toby;
    • Bonder, Claudine S.
    Publication type:
    Article
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    A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.

    Published in:
    EMBO Journal, 2017, v. 36, n. 14, p. 2107, doi. 10.15252/embj.201695347
    By:
    • Malenczyk, Katarzyna;
    • Girach, Fatima;
    • Szodorai, Edit;
    • Storm, Petter;
    • Segerstolpe, Åsa;
    • Tortoriello, Giuseppe;
    • Schnell, Robert;
    • Mulder, Jan;
    • Romanov, Roman A;
    • Borók, Erzsébet;
    • Piscitelli, Fabiana;
    • Di Marzo, Vincenzo;
    • Szabó, Gábor;
    • Sandberg, Rickard;
    • Kubicek, Stefan;
    • Lubec, Gert;
    • Hökfelt, Tomas;
    • Wagner, Ludwig;
    • Groop, Leif;
    • Harkany, Tibor
    Publication type:
    Article
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    Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin.

    Published in:
    Human Molecular Genetics, 2018, v. 27, n. 3, p. 546, doi. 10.1093/hmg/ddx413
    By:
    • Tönjes, Anke;
    • Scholz, Markus;
    • Krüger, Jacqueline;
    • Krause, Kerstin;
    • Schleinitz, Dorit;
    • Kirsten, Holger;
    • Gebhardt, Claudia;
    • Marzi, Carola;
    • Grallert, Harald;
    • Ladenvall, Claes;
    • Heyne, Henrike;
    • Laurila, Esa;
    • Kriebel, Jennifer;
    • Meisinger, Christa;
    • Rathmann, Wolfgang;
    • Gieger, Christian;
    • Groop, Leif;
    • Prokopenko, Inga;
    • Isomaa, Bo;
    • Beutner, Frank
    Publication type:
    Article