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Potent dual MAGL/FAAH inhibitor AKU-005 engages endocannabinoids to diminish meningeal nociception implicated in migraine pain.
- Published in:
- Journal of Headache & Pain, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s10194-023-01568-3
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- Publication type:
- Article
Low-Dose Doxycycline Treatment Normalizes Levels of Some Salivary Metabolites Associated with Oral Microbiota in Patients with Primary Sjögren's Syndrome.
- Published in:
- Metabolites (2218-1989), 2021, v. 11, n. 9, p. 595, doi. 10.3390/metabo11090595
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- Publication type:
- Article
Plasma and Cerebrospinal Fluid Pharmacokinetics of Naproxen in Children.
- Published in:
- Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1516, doi. 10.1177/0091270011418658
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- Publication type:
- Article
Plasma and Cerebrospinal Fluid Concentrations of Indomethacin in Children After Intravenous Administration.
- Published in:
- Journal of Clinical Pharmacology, 2007, v. 47, n. 1, p. 94, doi. 10.1177/0091270006295202
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- Publication type:
- Article
Metabolite Pattern Derived from Lactiplantibacillus plantarum—Fermented Rye Foods and In Vitro Gut Fermentation Synergistically Inhibits Bacterial Growth.
- Published in:
- Molecular Nutrition & Food Research, 2022, v. 66, n. 21, p. 1, doi. 10.1002/mnfr.202101096
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- Publication type:
- Article
Trans fat diet causes decreased brood size and shortened lifespan in Caenorhabditis elegans delta-6-desaturase mutant fat-3.
- Published in:
- Journal of Biochemical & Molecular Toxicology, 2011, v. 25, n. 5, p. 269, doi. 10.1002/jbt.20386
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- Publication type:
- Article
Buprenorphine plasma and cerebrospinal fluid concentrations in osteoarthritis patients during low-dose transdermal patch dosing.
- Published in:
- European Journal of Clinical Pharmacology, 2023, v. 79, n. 12, p. 1709, doi. 10.1007/s00228-023-03583-4
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- Publication type:
- Article
Mass-Spectrometric Identification of Anandamide and 2-Arachidonoylglycerol in Nematodes.
- Published in:
- Chemistry & Biodiversity, 2008, v. 5, n. 11, p. 2431, doi. 10.1002/cbdv.200890208
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- Publication type:
- Article
Non‐targeted metabolomics for the identification of plasma metabolites associated with organic anion transporting polypeptide 1B1 function.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13773
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- Publication type:
- Article
Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure.
- Published in:
- Cardiovascular Research, 2019, v. 115, n. 1, p. 107, doi. 10.1093/cvr/cvy155
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- Publication type:
- Article
In Vitro Human Metabolism and Inhibition Potency of Verbascoside for CYP Enzymes.
- Published in:
- Molecules, 2019, v. 24, n. 11, p. 2191, doi. 10.3390/molecules24112191
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- Publication type:
- Article
Fearful dogs have increased plasma glutamine and γ-glutamyl glutamine.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34321-x
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- Publication type:
- Article
A Non-Targeted LC-MS Profiling Reveals Elevated Levels of Carnitine Precursors and Trimethylated Compounds in the Cord Plasma of Pre-Eclamptic Infants.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32804-5
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- Publication type:
- Article
Whole grain intake associated molecule 5-aminovaleric acid betaine decreases β-oxidation of fatty acids in mouse cardiomyocytes.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31484-5
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- Publication type:
- Article
Serum Creatine, Not Neurofilament Light, Is Elevated in CHCHD10-Linked Spinal Muscular Atrophy.
- Published in:
- Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.793937
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- Publication type:
- Article
Non-targeted metabolite profiling highlights the potential of strawberry leaves as a resource for specific bioactive compounds.
- Published in:
- Journal of the Science of Food & Agriculture, 2017, v. 97, n. 7, p. 2182, doi. 10.1002/jsfa.8027
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- Publication type:
- Article
Quantitative determination of acetylcholine in microdialysis samples using liquid chromatography/atmospheric pressure spray ionization mass spectrometry.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2007, v. 21, n. 18, p. 2933, doi. 10.1002/rcm.3162
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- Publication type:
- Article
Dietary Caffeine and Brain Dopaminergic Function in Parkinson Disease.
- Published in:
- Annals of Neurology, 2024, v. 96, n. 2, p. 262, doi. 10.1002/ana.26957
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- Publication type:
- Article
Early-phase pharmacokinetics of enteral and parenteral nimodipine in patients with acute subarachnoid haemorrhage – a pilot study.
- Published in:
- European Journal of Clinical Pharmacology, 2007, v. 63, n. 4, p. 355, doi. 10.1007/s00228-007-0267-7
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- Publication type:
- Article
Metabolic changes in response to varying whole-grain wheat and rye intake.
- Published in:
- NPJ Science of Food, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41538-024-00247-0
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- Publication type:
- Article
Anthraquinone biocolourant dermocybin is metabolized whereas dermorubin is not in in vitro liver fractions and recombinant metabolic enzymes.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 6, p. 846, doi. 10.1111/bcpt.14013
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- Publication type:
- Article
Brain Pharmacokinetics of Two Prolyl Oligopeptidase Inhibitors, JTP-4819 and KYP-2047, in the Rat.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2011, v. 109, n. 6, p. 443, doi. 10.1111/j.1742-7843.2011.00747.x
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- Publication type:
- Article
Comparison of the Effects of Deramciclane, Ritanserin and Buspirone on Extracellular Dopamine and Its Metabolites in Striatum and Nucleus Accumbens of Freely Moving Rats.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2008, v. 102, n. 1, p. 50, doi. 10.1111/j.1742-7843.2007.00145.x
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- Publication type:
- Article
Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-19327-w
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- Publication type:
- Article
A non-targeted LC–MS metabolic profiling of pregnancy: longitudinal evidence from healthy and pre-eclamptic pregnancies.
- Published in:
- Metabolomics, 2021, v. 17, n. 2, p. 1, doi. 10.1007/s11306-020-01752-5
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- Publication type:
- Article
Aerobic exercise training and gut microbiome-associated metabolic shifts in women with overweight: a multi-omic study.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38357-6
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- Publication type:
- Article
Plasma and cerebrospinal fluid pharmacokinetics of flurbiprofen in children.
- Published in:
- British Journal of Clinical Pharmacology, 2010, v. 70, n. 4, p. 557, doi. 10.1111/j.1365-2125.2010.03720.x
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- Publication type:
- Article
Diclofenac readily penetrates the cerebrospinal fluid in children.
- Published in:
- British Journal of Clinical Pharmacology, 2008, v. 65, n. 6, p. 879, doi. 10.1111/j.1365-2125.2008.03126.x
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- Publication type:
- Article
Serum metabolites associated with wholegrain consumption using nontargeted metabolic profiling: a discovery and reproducibility study.
- Published in:
- European Journal of Nutrition, 2023, v. 62, n. 2, p. 713, doi. 10.1007/s00394-022-03010-x
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- Publication type:
- Article
Caffeine content in newborn hair correlates with maternal dietary intake.
- Published in:
- European Journal of Nutrition, 2021, v. 60, n. 1, p. 193, doi. 10.1007/s00394-020-02231-2
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- Publication type:
- Article
The Cerebrospinal Fluid Distribution of Postoperatively Administred Dexketoprofen and Etoricoxib and Their Effect on Pain and Inflammatory Markers in Patients Undergoing Hip Arthroplasty.
- Published in:
- Clinical Drug Investigation, 2016, v. 36, n. 7, p. 545, doi. 10.1007/s40261-016-0400-4
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- Publication type:
- Article
CMPF Does Not Associate with Impaired Glucose Metabolism in Individuals with Features of Metabolic Syndrome.
- Published in:
- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0124379
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- Publication type:
- Article
Discovery of Triterpenoids as Reversible Inhibitors of α/β-hydrolase Domain Containing 12 (ABHD12).
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0098286
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- Publication type:
- Article
Inhibition of human CYP1 enzymes by a classical inhibitor α‐naphthoflavone and a novel inhibitor N‐(3, 5‐dichlorophenyl)cyclopropanecarboxamide: An in vitro and in silico study.
- Published in:
- Chemical Biology & Drug Design, 2020, v. 95, n. 5, p. 520, doi. 10.1111/cbdd.13669
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- Publication type:
- Article
Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA<sub>1</sub> receptor signalling in rat brain cryosections without affecting global LPA degradation.
- Published in:
- BMC Pharmacology, 2012, v. 12, n. 1, p. 7, doi. 10.1186/1471-2210-12-7
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- Publication type:
- Article
Metabolomics of Synovial Fluid and Infrapatellar Fat Pad in Patients with Osteoarthritis or Rheumatoid Arthritis.
- Published in:
- Inflammation, 2022, v. 45, n. 3, p. 1101, doi. 10.1007/s10753-021-01604-x
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- Publication type:
- Article
Amino Acid Promoieties Alter Valproic Acid Pharmacokinetics and Enable Extended Brain Exposure.
- Published in:
- Neurochemical Research, 2016, v. 41, n. 10, p. 2797, doi. 10.1007/s11064-016-1996-8
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- Publication type:
- Article
A non-targeted metabolite profiling pilot study suggests that-tryptophan and lipid metabolisms are linked with ADHD-like behaviours in dogs.
- Published in:
- Behavioral & Brain Functions, 2016, v. 21, p. 1, doi. 10.1186/s12993-016-0112-1
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- Publication type:
- Article
Non-targeted metabolite profiling reveals changes in oxidative stress, tryptophan and lipid metabolisms in fearful dogs.
- Published in:
- Behavioral & Brain Functions, 2016, v. 12, p. 1, doi. 10.1186/s12993-016-0091-2
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- Publication type:
- Article
Combined ipsilateral limb use score as an index of motor deficits and neurorestoration in parkinsonian rats.
- Published in:
- Journal of Neuroscience Research, 2017, v. 95, n. 9, p. 1858, doi. 10.1002/jnr.24022
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- Publication type:
- Article
Pharmacokinetics of buprenorphine in pregnant sheep after intravenous injection.
- Published in:
- Pharmacology Research & Perspectives, 2021, v. 9, n. 2, p. 1, doi. 10.1002/prp2.726
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- Publication type:
- Article
Metabolic alterations in Parkinson's disease astrocytes.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71329-8
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- Publication type:
- Article
Visualization of 2-arachidonoylglycerol accumulation and cannabinoid CB<sub>1</sub> receptor activity in rat brain cryosections by functional autoradiography.
- Published in:
- Journal of Neurochemistry, 2007, v. 101, n. 4, p. 972, doi. 10.1111/j.1471-4159.2006.04403.x
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- Publication type:
- Article
Ganciclovir and Its Hemocompatible More Lipophilic Derivative Can Enhance the Apoptotic Effects of Methotrexate by Inhibiting Breast Cancer Resistance Protein (BCRP).
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7727, doi. 10.3390/ijms22147727
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- Publication type:
- Article
Solanidine is a sensitive and specific dietary biomarker for CYP2D6 activity.
- Published in:
- Human Genomics, 2024, v. 18, n. 1, p. 1, doi. 10.1186/s40246-024-00579-8
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- Publication type:
- Article
Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study.
- Published in:
- Scientific Reports, 2017, p. 46337, doi. 10.1038/srep46337
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- Publication type:
- Article
Cerebrospinal fluid distribution of ketoprofen after intravenous administration in young children.
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- 2006
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- Publication type:
- journal article
L-Type Amino Acid Transporter 1-Utilizing Prodrugs of Ketoprofen Can Efficiently Reduce Brain Prostaglandin Levels.
- Published in:
- Pharmaceutics, 2020, v. 12, n. 4, p. 344, doi. 10.3390/pharmaceutics12040344
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- Publication type:
- Article
Changes in the metabolic profile of human male postmortem frontal cortex and cerebrospinal fluid samples associated with heavy alcohol use.
- Published in:
- Addiction Biology, 2021, v. 26, n. 6, p. 1, doi. 10.1111/adb.13035
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- Publication type:
- Article
Metabolic Profiling of High Egg Consumption and the Associated Lower Risk of Type 2 Diabetes in Middle‐Aged Finnish Men.
- Published in:
- Molecular Nutrition & Food Research, 2019, v. 63, n. 5, p. N.PAG, doi. 10.1002/mnfr.201800605
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- Publication type:
- Article