Works by Lehmann-Horn, Klaus

Results: 14

Update on the Autoimmune Pathology of Multiple Sclerosis: B-Cells as Disease-Drivers and Therapeutic Targets.

Published in:

European Neurology, 2015, v. 73, n. 3/4, p. 238, doi. 10.1159/000377675

By:

von Büdingen, H.-Christian;
Palanichamy, Arumugam;
Lehmann-Horn, Klaus;
Michel, Brady A.;
Zamvil, Scott S.

Publication type:

Article

Developmental maturation of innate immune cell function correlates with susceptibility to central nervous system autoimmunity.

Published in:

European Journal of Immunology, 2013, v. 43, n. 8, p. 2078, doi. 10.1002/eji.201343338

By:

Hertzenberg, Deetje;
Lehmann‐Horn, Klaus;
Kinzel, Silke;
Husterer, Veronika;
Cravens, Petra D.;
Kieseier, Bernd C.;
Hemmer, Bernhard;
Brück, Wolfgang;
Zamvil, Scott S.;
Stüve, Olaf;
Weber, Martin S.

Publication type:

Article

Deciphering the Role of B Cells in Multiple Sclerosis--Towards Specific Targeting of Pathogenic Function.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 10, p. 2048, doi. 10.3390/ijms18102048

By:

Lehmann-Horn, Klaus;
Kinzel, Silke;
Weber, Martin S.

Publication type:

Article

Intrathecal anti- CD20 efficiently depletes meningeal B cells in CNS autoimmunity.

Published in:

Annals of Clinical & Translational Neurology, 2014, v. 1, n. 7, p. 490, doi. 10.1002/acn3.71

By:

Lehmann‐Horn, Klaus;
Kinzel, Silke;
Feldmann, Linda;
Radelfahr, Florentine;
Hemmer, Bernhard;
Traffehn, Sarah;
Bernard, Claude C. A.;
Stadelmann, Christine;
Brück, Wolfgang;
Weber, Martin S.

Publication type:

Article

Single-cell profiling indicates a high similarity between immune cells in the cerebrospinal fluid and in meningeal ectopic lymphoid tissue in experimental autoimmune encephalomyelitis.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1400641

By:

Georgieva, Tanya;
Diddens, Jolien;
Friedrich, Verena;
Lepennetier, Gildas;
Brand, Rosa Margareta;
Lehmann-Horn, Klaus

Publication type:

Article

IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity.

Published in:

Acta Neuropathologica, 2023, v. 145, n. 4, p. 461, doi. 10.1007/s00401-023-02552-6

By:

Geladaris, Anastasia;
Häusser-Kinzel, Silke;
Pretzsch, Roxanne;
Nissimov, Nitzan;
Lehmann-Horn, Klaus;
Häusler, Darius;
Weber, Martin S.

Publication type:

Article

Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen.

Published in:

Acta Neuropathologica, 2016, v. 132, n. 1, p. 43, doi. 10.1007/s00401-016-1559-8

By:

Kinzel, Silke;
Lehmann-Horn, Klaus;
Torke, Sebastian;
Häusler, Darius;
Winkler, Anne;
Stadelmann, Christine;
Payne, Natalie;
Feldmann, Linda;
Saiz, Albert;
Reindl, Markus;
Lalive, Patrice;
Bernard, Claude;
Brück, Wolfgang;
Weber, Martin

Publication type:

Article

B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity.

Published in:

Annals of Neurology, 2015, v. 77, n. 5, p. 902, doi. 10.1002/ana.24387

By:

Lehmann‐Horn, Klaus;
Sagan, Sharon A.;
Bernard, Claude C.A.;
Sobel, Raymond A.;
Zamvil, Scott S.

Publication type:

Article

B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity.

Published in:

Annals of Neurology, 2010, v. 68, n. 3, p. 369, doi. 10.1002/ana.22081

By:

Weber, Martin S.;
Prod'homme, Thomas;
Patarroyo, Juan C.;
Molnarfi, Nicolas;
Karnezis, Tara;
Lehmann-Horn, Klaus;
Danilenko, Dimitry M.;
Eastham-Anderson, Jeffrey;
Slavin, Anthony J.;
Linington, Christopher;
Bernard, Claude C. A.;
Martin, Flavius;
Zamvil, Scott S.

Publication type:

Article

Repetitive Pertussis Toxin Promotes Development of Regulatory T Cells and Prevents Central Nervous System Autoimmune Disease.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0016009

By:

Weber, Martin S.;
Benkhoucha, Mahdia;
Lehmann-Horn, Klaus;
Hertzenberg, Deetje;
Sellner, Johann;
Santiago-Raber, Marie-Laure;
Chofflon, Michel;
Hemmer, Bernhard;
Zamvil, Scott S.;
Lalive, Patrice H.

Publication type:

Article

Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.18246

By:

Feng Mei;
Lehmann-Horn, Klaus;
Shen, Yun-An A.;
Rankin, Kelsey A.;
Stebbins, Karin J.;
Lorrain, Daniel S.;
Pekarek, Kara;
Sagan, Sharon A.;
Xiao, Lan;
Teuscher, Cory;
von Büdingen, H-Christian;
Wess, Jürgen;
Lawrence, J. Josh;
Green, Ari J.;
Fancy, Stephen P. J.;
Zamvil, Scott S.;
Chan, Jonah R.

Publication type:

Article

Intrathecally Expanding B Cell Clones in Herpes Simplex Encephalitis: A Case Report.

Published in:

Neurology & Therapy, 2022, v. 11, n. 2, p. 905, doi. 10.1007/s40120-022-00330-2

By:

Coronel-Castello, Shila P.;
Lepennetier, Gildas;
Diddens, Jolien;
Friedrich, Verena;
Pfaller, Monika;
Hemmer, Bernhard;
Lehmann-Horn, Klaus

Publication type:

Article

Targeting B cells in the treatment of multiple sclerosis: recent advances and remaining challenges.

Published in:

Therapeutic Advances in Neurological Disorders, 2013, v. 6, n. 3, p. 161, doi. 10.1177/1756285612474333

By:

Lehmann-Horn, Klaus;
Kronsbein, Helena C.;
Weber, Martin S.

Publication type:

Article

Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis.

Published in:

2019

By:

Cruz-Herranz, Andrés;
Dietrich, Michael;
Hilla, Alexander M.;
Yiu, Hao H.;
Levin, Marc H.;
Hecker, Christina;
Issberner, Andrea;
Hallenberger, Angelika;
Cordano, Christian;
Lehmann-Horn, Klaus;
Balk, Lisanne J.;
Aktas, Orhan;
Ingwersen, Jens;
von Gall, Charlotte;
Hartung, Hans-Peter;
Zamvil, Scott S.;
Fischer, Dietmar;
Albrecht, Philipp;
Green, Ari J.

Publication type:

journal article