Works matching AU Lehman, Melanie

Results: 22

Artificial intelligence driven tumor risk stratification from single-cell transcriptomics using phenotype algebra.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98469

By:

Bhattacharya, Namrata;
Rockstroh, Anja;
Deshpande, Sanket Suhas;
Thomas, Sam Koshy;
Yadav, Anunay;
Goswami, Chitrita;
Chawla, Smriti;
Solomon, Pierre;
Fourgeux, Cynthia;
Ahuja, Gaurav;
Hollier, Brett;
Kumar, Himanshu;
Roquilly, Antoine;
Poschmann, Jeremie;
Lehman, Melanie;
Nelson, Colleen C.;
Sengupta, Debarka

Publication type:

Article

Discovery of thalicthuberine as a novel antimitotic agent from nature that disrupts microtubule dynamics and induces apoptosis in prostate cancer cells.

Published in:

Cell Cycle, 2018, v. 17, n. 5, p. 652, doi. 10.1080/15384101.2017.1356512

By:

Levrier, Claire;
Rockstroh, Anja;
Gabrielli, Brian;
Kavallaris, Maria;
Lehman, Melanie;
Davis, Rohan A.;
Sadowski, Martin C.;
Nelson, Colleen C.

Publication type:

Article

The molecular function of kallikrein‐related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.

Published in:

Molecular Oncology, 2020, v. 14, n. 1, p. 105, doi. 10.1002/1878-0261.12587

By:

Kryza, Thomas;
Bock, Nathalie;
Lovell, Scott;
Rockstroh, Anja;
Lehman, Melanie L.;
Lesner, Adam;
Panchadsaram, Janaththani;
Silva, Lakmali Munasinghage;
Srinivasan, Srilakshmi;
Snell, Cameron E.;
Williams, Elizabeth D.;
Fazli, Ladan;
Gleave, Martin;
Batra, Jyotsna;
Nelson, Colleen;
Tate, Edward W.;
Harris, Jonathan;
Hooper, John D.;
Clements, Judith A.

Publication type:

Article

miRDeep*: an integrated application tool for miRNA identification from RNA sequencing data.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 2, p. 727, doi. 10.1093/nar/gks1187

By:

An, Jiyuan;
Lai, John;
Lehman, Melanie L.;
Nelson, Colleen C.

Publication type:

Article

Androgen receptor and nutrient signaling pathways coordinate increased amino acid transport in prostate cancer progression.

Published in:

2012

By:

Qian Wang;
Bailey, Charles G.;
Ng, Cynthia;
Tiffen, Jessamy;
Thoeng, Annora;
Minnas, Vineet;
Lehman, Melanie L.;
Hendy, Stephen C.;
Buchanan, Grant;
Nelson, Colleen C.;
Rasko, John E. J.;
Holst, Jeff

Publication type:

Abstract

Analysis of androgen and anti-androgen regulation of KLK-related peptidase 2, 3, and 4 alternative transcripts in prostate cancer.

Published in:

Biological Chemistry, 2014, v. 395, n. 9, p. 1127, doi. 10.1515/hsz-2014-0149

By:

Lai, John;
Jiyuan An;
Nelson, Colleen C.;
Lehman, Melanie L.;
Batra, Jyotsna;
Clements, Judith A.

Publication type:

Article

Cell membranes and multilamellar vesicles: Influence of pH on solvent induced damage.

Published in:

Lipids, 1992, v. 27, n. 9, p. 694, doi. 10.1007/BF02536027

By:

Jacobsohn, Myra;
Lehman, Melanie;
Jacobsohn, Gert

Publication type:

Article

Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer.

Published in:

Cancer & Metabolism, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40170-020-00217-6

By:

Tousignant, Kaylyn D.;
Rockstroh, Anja;
Poad, Berwyck L. J.;
Talebi, Ali;
Young, Reuben S. E.;
Taherian Fard, Atefeh;
Gupta, Rajesh;
Zang, Tuo;
Wang, Chenwei;
Lehman, Melanie L.;
Swinnen, Johan V.;
Blanksby, Stephen J.;
Nelson, Colleen C.;
Sadowski, Martin C.

Publication type:

Article

Gene expression based inference of cancer drug sensitivity.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33291-z

By:

Chawla, Smriti;
Rockstroh, Anja;
Lehman, Melanie;
Ratther, Ellca;
Jain, Atishay;
Anand, Anuneet;
Gupta, Apoorva;
Bhattacharya, Namrata;
Poonia, Sarita;
Rai, Priyadarshini;
Das, Nirjhar;
Majumdar, Angshul;
Jayadeva;
Ahuja, Gaurav;
Hollier, Brett G.;
Nelson, Colleen C.;
Sengupta, Debarka

Publication type:

Article

Relaxin drives Wnt signaling through upregulation of PCDHY in prostate cancer.

Published in:

Prostate, 2010, v. 70, n. 10, p. 1134, doi. 10.1002/pros.21148

By:

Thompson, Vanessa C.;
Hurtado-Coll, Antonio;
Turbin, Dmitry;
Fazli, Ladan;
Lehman, Melanie L.;
Gleave, Martin E.;
Nelson, Colleen C.

Publication type:

Article

Arachidonic acid activation of intratumoral steroid synthesis during prostate cancer progression to castration resistance.

Published in:

Prostate, 2010, v. 70, n. 3, p. 239, doi. 10.1002/pros.21057

By:

Locke, Jennifer A.;
Guns, Emma S. Tomlinson;
Lehman, Melanie L.;
Ettinger, Susan;
Zoubeidi, Amina;
Lubik, Amy;
Margiotti, Katia;
Fazli, Ladan;
Adomat, Hans;
Wasan, Kishor M.;
Gleave, Martin E.;
Nelson, Colleen C.

Publication type:

Article

Fusion transcript loci share many genomic features with non-fusion loci.

Published in:

BMC Genomics, 2015, v. 16, p. 1, doi. 10.1186/s12864-015-2235-4

By:

Lai, John;
Jiyuan An;
Seim, Inge;
Walpole, Carina;
Hoffman, Andrea;
Moya, Leire;
Srinivasan, Srilakshmi;
Perry-Keene, Joanna L.;
Chenwei Wang;
Lehman, Melanie L.;
Nelson, Colleen C.;
Clements, Judith A.;
Batra, Jyotsna

Publication type:

Article

RNASeqBrowser: A genome browser for simultaneous visualization of raw strand specific RNAseq reads and UCSC genome browser custom tracks.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12864-015-1346-2

By:

Jiyuan An;
Lai, John;
Wood, David L. A.;
Sajjanhar, Atul;
Chenwei Wang;
Tevz, Gregor;
Lehman, Melanie L.;
Nelson, Colleen C.

Publication type:

Article

miRPlant: an integrated tool for identification of plant miRNA from RNA sequencing data.

Published in:

BMC Bioinformatics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2105-15-275

By:

Jiyuan An;
Lai, John;
Sajjanhar, Atul;
Lehman, Melanie L.;
Nelson, Colleen C.

Publication type:

Article

Insulin Enhances Migration and Invasion in Prostate Cancer Cells by Up-Regulation of FOXC2.

Published in:

Frontiers in Endocrinology, 2019, p. 1, doi. 10.3389/fendo.2019.00481

By:

Sarkar, Phoebe L.;
Lee, Wendy;
Williams, Elizabeth D.;
Lubik, Amy A.;
Stylianou, Nataly;
Shokoohmand, Ali;
Lehman, Melanie L.;
Hollier, Brett G.;
Gunter, Jennifer H.;
Nelson, Colleen C.

Publication type:

Article

Phenotypic Characterization of Prostate Cancer LNCaP Cells Cultured within a Bioengineered Microenvironment.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0040217

By:

Sieh, Shirly;
Taubenberger, Anna V.;
Rizzi, Simone C.;
Sadowski, Martin;
Lehman, Melanie L.;
Rockstroh, Anja;
Jiyuan An;
Clements, Judith A.;
Nelson, Colleen C.;
Hutmacher, Dietmar W.;
Wilson, Elizabeth

Publication type:

Article

Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development.

Published in:

JNCI: Journal of the National Cancer Institute, 2013, v. 105, n. 19, p. 1463, doi. 10.1093/jnci/djt241

By:

Wang, Qian;
Tiffen, Jessamy;
Bailey, Charles G.;
Lehman, Melanie L.;
Ritchie, William;
Fazli, Ladan;
Metierre, Cynthia;
Feng, Yue (Julie);
Li, Estelle;
Gleave, Martin;
Buchanan, Grant;
Nelson, Colleen C.;
Rasko, John E. J.;
Holst, Jeff

Publication type:

Article

Integrin-linked kinase as a target for ERG-mediated invasive properties in prostate cancer models.

Published in:

Carcinogenesis, 2012, v. 33, n. 12, p. 2558, doi. 10.1093/carcin/bgs285

By:

Becker-Santos, Daiana D.;
Guo, Yubin;
Ghaffari, Mazyar;
Vickers, Elaine D.;
Lehman, Melanie;
Altamirano-Dimas, Manuel;
Oloumi, Arusha;
Furukawa, Junya;
Sharma, Manju;
Wang, Yuzhuo;
Dedhar, Shoukat;
Cox, Michael E.

Publication type:

Article

Neuropilin-1 is over-expressed in claudin-low breast cancer and promotes tumor progression through acquisition of stem cell characteristics and RAS/MAPK pathway activation.

Published in:

2022

By:

Tang, Yu Hin;
Rockstroh, Anja;
Sokolowski, Kamil A.;
Lynam, Layla-Rose;
Lehman, Melanie;
Thompson, Erik W.;
Gregory, Philip A.;
Nelson, Colleen C.;
Volpert, Marianna;
Hollier, Brett G.

Publication type:

journal article

Erratum to: Fusion transcript loci share many genomic features with non-fusion loci.

Published in:

BMC Genomics, 2016, v. 17, p. 424, doi. 10.1186/s12864-016-2751-x

By:

Lai, John;
An, Jiyuan;
Seim, Inge;
Walpole, Carina;
Hoffman, Andrea;
Moya, Leire;
Srinivasan, Srilakshmi;
Perry-Keene, Joanna L.;
Chenwei Wang;
Lehman, Melanie L.;
Nelson, Colleen C.;
Clements, Judith A.;
Batra, Jyotsna

Publication type:

Article

Targeting valine catabolism to inhibit metabolic reprogramming in prostate cancer.

Published in:

Cell Death & Disease, 2024, v. 15, n. 7, p. 1, doi. 10.1038/s41419-024-06893-2

By:

Bidgood, Charles L.;
Philp, Lisa K.;
Rockstroh, Anja;
Lehman, Melanie;
Nelson, Colleen C.;
Sadowski, Martin C.;
Gunter, Jennifer H.

Publication type:

Article

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development.

Published in:

Journal of Pathology, 2015, v. 236, n. 3, p. 278, doi. 10.1002/path.4518

By:

Wang, Qian;
Hardie, Rae‐Anne;
Hoy, Andrew J;
van Geldermalsen, Michelle;
Gao, Dadi;
Fazli, Ladan;
Sadowski, Martin C;
Balaban, Seher;
Schreuder, Mark;
Nagarajah, Rajini;
Wong, Justin J‐L;
Metierre, Cynthia;
Pinello, Natalia;
Otte, Nicholas J;
Lehman, Melanie L;
Gleave, Martin;
Nelson, Colleen C;
Bailey, Charles G;
Ritchie, William;
Rasko, John EJ

Publication type:

Article