Works by Legro, Richard S.

Results: 153

Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.

Published in:

2020

By:

Dapas, Matthew;
Lin, Frederick T. J.;
Nadkarni, Girish N.;
Sisk, Ryan;
Legro, Richard S.;
Urbanek, Margrit;
Hayes, M. Geoffrey;
Dunaif, Andrea

Publication type:

journal article

A brief update on the evidence supporting the treatment of infertility in polycystic ovary syndrome.

Published in:

Australian & New Zealand Journal of Obstetrics & Gynaecology, 2019, v. 59, n. 6, p. 867, doi. 10.1111/ajo.13051

By:

Costello, Michael F.;
Misso, Marie L.;
Balen, Adam;
Boyle, Jacqueline;
Devoto, Luigi;
Garad, Rhonda M.;
Hart, Roger;
Johnson, Louise;
Jordan, Cailin;
Legro, Richard S.;
Norman, Rob J.;
Moran, Lisa;
Mocanu, Edgar;
Qiao, Jie;
Rodgers, Ray J.;
Rombauts, Luk;
Tassone, Eliza C.;
Thangaratinam, Shakila;
Vanky, Eszter;
Teede, Helena J.

Publication type:

Article

Menstrual Disorders in Insulin-Resistant States.

Published in:

Diabetes Spectrum, 1997, v. 10, n. 3, p. 185

By:

Legro, Richard S.;
Dunaif, Andrea

Publication type:

Article

Exclusion of Women of Childbearing Potential in Clinical Trials of Type 2 Diabetes Medications: A Review of Protocol-Based Barriers to Enrollment.

Published in:

2016

By:

Phelan, Alannah L.;
Kunselman, Allen R.;
Chuang, Cynthia H.;
Raja-Khan, Nazia T.;
Legro, Richard S.

Publication type:

journal article

A multi-center randomized trial of two different intravenous fluids during labor.

Published in:

2016

By:

Dapuzzo-Argiriou, Lisa M.;
Smulian, John C.;
Rochon, Meredith L.;
Galdi, Luisa;
Kissling, Jessika M.;
Schnatz, Peter F.;
Gonzalez Rios, Angel;
Airoldi, James;
Carrillo, Mary Anne;
Maines, Jaimie;
Kunselman, Allen R.;
Repke, John;
Legro, Richard S.

Publication type:

journal article

Risk of foetal harm with letrozole use in fertility treatment: a systematic review and meta-analysis.

Published in:

2021

By:

Pundir, Jyotsna;
Achilli, Chiara;
Bhide, Priya;
Sabatini, Luca;
Legro, Richard S;
Rombauts, Luk;
Teede, Helena;
Coomarasamy, Arri;
Zamora, Javier;
Thangaratinam, Shakila

Publication type:

journal article

Cardiometabolic health in offspring of women with PCOS compared to healthy controls: a systematic review and individual participant data meta-analysis.

Published in:

2020

By:

Gunning, Marlise N;
Petermann, Teresa Sir;
Crisosto, Nicolas;
Rijn, Bas B van;
Wilde, Marlieke A de;
Christ, Jacob P;
Uiterwaal, C S P M;
Jager, Wilco de;
Eijkemans, Marinus J C;
Kunselman, Allen R;
Legro, Richard S;
Fauser, Bart C J M;
Sir Petermann, Teresa;
van Rijn, Bas B;
de Wilde, Marlieke A;
de Jager, Wilco

Publication type:

journal article

First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis.

Published in:

2019

By:

Wang, Rui;
Li, Wentao;
Bordewijk, Esmée M;
Legro, Richard S;
Zhang, Heping;
Wu, Xiaoke;
Gao, Jingshu;
Morin-Papunen, Laure;
Homburg, Roy;
König, Tamar E;
Moll, Etelka;
Kar, Sujata;
Huang, Wei;
Johnson, Neil P;
Amer, Saad A;
Vegetti, Walter;
Palomba, Stefano;
Falbo, Angela;
Özmen, Ülkü;
Nazik, Hakan

Publication type:

journal article

The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance.

Published in:

2016

By:

Balen, Adam H.;
Morley, Lara C.;
Misso, Marie;
Franks, Stephen;
Legro, Richard S.;
Wijeyaratne, Chandrika N.;
Stener-Victorin, Elisabet;
Fauser, Bart C. J. M.;
Norman, Robert J.;
Teede, Helena

Publication type:

journal article

Mindfulness-Based Stress Reduction in Women with Overweight or Obesity: A Randomized Clinical Trial.

Published in:

2017

By:

Raja‐Khan, Nazia;
Agito, Katrina;
Shah, Julie;
Stetter, Christy M.;
Gustafson, Theresa S.;
Socolow, Holly;
Kunselman, Allen R.;
Reibel, Diane K.;
Legro, Richard S.;
Raja-Khan, Nazia

Publication type:

journal article

Letter to Liu et al.'s “Efficacy of Exenatide on weight loss, metabolic parameters and pregnancy in overweight/obese polycystic ovary syndrome”.

Published in:

2018

By:

Legro, Richard S.

Publication type:

Letter to the Editor

Age-stratified thresholds of anti-Müllerian hormone improve prediction of polycystic ovary syndrome over a population-based threshold.

Published in:

Clinical Endocrinology, 2017, v. 87, n. 6, p. 733, doi. 10.1111/cen.13415

By:

Quinn, Molly M.;
Kao, Chia‐Ning;
Ahmad, Asima K.;
Haisenleder, Daniel J.;
Santoro, Nanette;
Eisenberg, Esther;
Legro, Richard S.;
Cedars, Marcelle I.;
Huddleston, Heather G.

Publication type:

Article

Impact of hormonal contraception and weight loss on high-density lipoprotein cholesterol efflux and lipoprotein particles in women with polycystic ovary syndrome.

Published in:

Clinical Endocrinology, 2017, v. 86, n. 5, p. 739, doi. 10.1111/cen.13310

By:

Dokras, Anuja;
Playford, Martin;
Kris‐Etherton, Penny M.;
Kunselman, Allen R.;
Stetter, Christy M.;
Williams, Nancy I.;
Gnatuk, Carol L.;
Estes, Stephanie J.;
Sarwer, David B.;
Allison, Kelly C.;
Coutifaris, Christos;
Mehta, Nehal;
Legro, Richard S.

Publication type:

Article

PCOS Forum: research in polycystic ovary syndrome today and tomorrow.

Published in:

Clinical Endocrinology, 2011, v. 74, n. 4, p. 424, doi. 10.1111/j.1365-2265.2010.03956.x

By:

Pasquali, Renato;
Stener-Victorin, Elisabet;
Yildiz, Bulent O.;
Duleba, Antoni J.;
Hoeger, Kathleen;
Mason, Helen;
Homburg, Roy;
Hickey, Theresa;
Franks, Steve;
Tapanainen, Juha S.;
Balen, Adam;
Abbott, David H.;
Diamanti-Kandarakis, Evanthia;
Legro, Richard S.

Publication type:

Article

PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women.

Published in:

Molecular Human Reproduction, 2009, v. 15, n. 8, p. 459, doi. 10.1093/molehr/gap035

By:

Chen, Chen;
Wickenheisser, Jessica;
Ewens, Kathryn G.;
Ankener, Wendy;
Legro, Richard S.;
Dunaif, Andrea;
McAllister, Jan M.;
Spielman, Richard S.;
Strauss, Jerome F.

Publication type:

Article

Women's Awareness of Their Contraceptive Benefits Under the Patient Protection and Affordable Care Act.

Published in:

American Journal of Public Health, 2015, v. 105, p. S713, doi. 10.2105/AJPH.2015.302829

By:

Chuang, Cynthia H.;
Mitchell, Julie L.;
Velott, Diana L.;
Legro, Richard S.;
Lehman, Erik B.;
Confer, Lindsay;
Weisman, Carol S.

Publication type:

Article

Polycystic Ovary Syndrome and Infertility.

Published in:

JAMA: Journal of the American Medical Association, 2007, v. 297, n. 23, p. 2583, doi. 10.1001/jama.297.23.2583-a

By:

Legro, Richard S.

Publication type:

Article

A 27-Year-Old Woman With a Diagnosis of Polycystic Ovary Syndrome.

Published in:

JAMA: Journal of the American Medical Association, 2007, v. 297, n. 5, p. 509, doi. 10.1001/jama.297.5.509

By:

Legro, Richard S.

Publication type:

Article

Live birth after fresh embryo transfer vs elective embryo cryopreservation/frozen embryo transfer in women with polycystic ovary syndrome undergoing IVF (FreFro-PCOS): study protocol for a multicenter, prospective, randomized controlled clinical trial.

Published in:

Trials, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1745-6215-15-154

By:

Yuhua Shi;
Daimin Wei;
Xiaoyan Liang;
Yun Sun;
Jiayin Liu;
Yunxia Cao;
Bo Zhang;
Legro, Richard S.;
Heping Zhang;
Zi-Jiang Chen

Publication type:

Article

Live birth after fresh embryo transfer vs elective embryo cryopreservation/frozen embryo transfer in women with polycystic ovary syndrome undergoing IVF (FreFro-PCOS): study protocol for a multicenter, prospective, randomized controlled clinical trial.

Published in:

2014

By:

Shi, Yuhua;
Wei, Daimin;
Liang, Xiaoyan;
Sun, Yun;
Liu, Jiayin;
Cao, Yunxia;
Zhang, Bo;
Legro, Richard S;
Zhang, Heping;
Chen, Zi-Jiang

Publication type:

journal article

Metabolic Phenotype in the Brothers of Women with Polycystic Ovary Syndrome.

Published in:

Diabetes Care, 2008, v. 31, n. 6, p. 1237, doi. 10.2337/dc07-2190

By:

Sam, Susan;
Coviello, Andrea D.;
Sung, Yeon-Ah;
Legro, Richard S.;
Dunaif, Andrea

Publication type:

Article

Association Between Mode of First Delivery and Subsequent Fecundity and Fertility.

Published in:

JAMA Network Open, 2020, v. 3, n. 4, p. e203076, doi. 10.1001/jamanetworkopen.2020.3076

By:

Kjerulff, Kristen H.;
Paul, Ian M.;
Weisman, Carol S.;
Hillemeier, Marianne M.;
Wang, Ming;
Legro, Richard S.;
Repke, John T.

Publication type:

Article

POSITION STATEMENT: Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 11, p. 4237, doi. 10.1210/jc.2006-0178

By:

Azziz, Ricardo;
Carmina, Enrico;
Dewailly, Didier;
Diamanti-Kandarakis, Evanthia;
Escobar-Morreale, Hector F.;
Futterweit, Walter;
Janssen, Onno E.;
Legro, Richard S.;
Norman, Robert J.;
Taylor, Ann E.;
Witchel, Selma F.

Publication type:

Article

Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance.

Published in:

2006

By:

Coviello, Andrea D.;
Legro, Richard S.;
Dunaif, Andrea

Publication type:

journal article

Prevalence and Predictors of the Metabolic Syndrome in Women with Polycystic Ovary Syndrome.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 1, p. 48, doi. 10.1210/jc.2005-1329

By:

Ehrmann, David A.;
Liljenquist, David R.;
Kasza, Kristen;
Azziz, Ricardo;
Legro, Richard S.;
Ghazzi, Mahmoud N.

Publication type:

Article

Increased Transcription and Increased Messenger Ribonucleic Acid (mRNA) Stability Contribute to Increased GATA6 mRNA Abundance in Polycystic Ovary Syndrome Theca Cells.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 12, p. 6596, doi. 10.1210/jc.2005-0890

By:

Ho, Clement K. M.;
Wood, Jennifer R.;
Stewart, Douglas R.;
Ewens, Kathryn;
Ankener, Wendy;
Wickenheisser, Jessica;
Nelson-Degrave, Velen;
Zhibing Zhang;
Legro, Richard S.;
Dunaif, Andrea;
McAllister, Jan M.;
Spielman, Richard;
Strauss III, Jerome F.

Publication type:

Article

Retinoids and retinol differentially regulate steroid biosynthesis in ovarian theca cells isolated from normal cycling women and women with polycystic ovary syndrome.

Published in:

2005

By:

Wickenheisser, Jessica K;
Nelson-DeGrave, Velen L;
Hendricks, Karen L;
Legro, Richard S;
Strauss, Jerome F 3rd;
McAllister, Jan M

Publication type:

journal article

Dyslipidemia and metabolic syndrome in the sisters of women with polycystic ovary syndrome.

Published in:

2005

By:

Sam, Susan;
Legro, Richard S;
Bentley-Lewis, Rhonda;
Dunaif, Andrea

Publication type:

journal article

Changes in Glucose Tolerance over Time in Women with Polycystic Ovary Syndrome: A Controlled Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 6, p. 3236, doi. 10.1210/jc.2004-1843

By:

Legro, Richard S.;
Gnatuk, Carol L.;
Kunselman, Allen R.;
Dunaif, Andrea

Publication type:

Article

Polycystic Ovaries Are Common in Women with Hyperandrogenic Chronic Anovulation but Do Not Predict Metabolic or Reproductive Phenotype.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 5, p. 2571, doi. 10.1210/jc.2004-0219

By:

Legro, Richard S.;
Chiu, Percy;
Kunselman, Allen R.;
Bentley, Christina M.;
Dodson, William C.;
Dunaif, Andrea

Publication type:

Article

Effects of Race and Family History of Type 2 Diabetes on Metabolic Status of Women with Polycystic Ovary Syndrome.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 1, p. 66, doi. 10.1210/jc.2004-0229

By:

Ehrmann, David A.;
Kasza, Kristen;
Azziz, Ricardo;
Legro, Richard S.;
Ghazzi, Mahmoud N.

Publication type:

Article

Minimal Response of Circulating Lipids in Women with Polycystic Ovary Syndrome to Improvement in Insulin Sensitivity with Troglitazone.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 11, p. 5137, doi. 10.1210/jc.2003-030044

By:

LEGRO, RICHARD S.;
AZZIZ, RICARDO;
EHRMANN, DAVID;
FERESHETIAN, ANITA GMEREK;
O’KEEFE, MARY;
GHAZZI, MAHMOUD N.

Publication type:

Article

Urinary Free Cortisol Increases in Adolescent Caucasian Females during Perimenarche.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 1, p. 215, doi. 10.1210/jc.2002-020256

By:

LEGRO, RICHARD S.;
LIN, HUNG MO;
DEMERS, LAURENCE M.;
LLOYD, TOM

Publication type:

Article

Elevated dehydroepiandrosterone sulfate levels as the reproductive phenotype in the brothers of women with polycystic ovary syndrome.

Published in:

2002

By:

Legro, Richard S;
Kunselman, Allen R;
Demers, Lawrence;
Wang, Steve C;
Bentley-Lewis, Rhonda;
Dunaif, Andrea

Publication type:

journal article

Insulin resistance in the sisters of women with polycystic ovary syndrome: association with hyperandrogenemia rather than menstrual irregularity.

Published in:

2002

By:

Legro, Richard S;
Bentley-Lewis, Rhonda;
Driscoll, Deborah;
Wang, Steve C;
Dunaif, Andrea

Publication type:

journal article

The Biochemical Basis for Increased Testosterone Production in Theca Cells Propagated from Patients with Polycystic Ovary Syndrome.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 12, p. 5925, doi. 10.1210/jcem.86.12.8088

By:

NELSON, VELEN L.;
KE-NAN QIN;
ROSENFIELD, ROBERT L.;
WOOD, JENNIFER R.;
PENNING, TREVOR M.;
LEGRO, RICHARD S.;
STRAUSS III, JEROME F.;
MCALLISTER, JAN M.

Publication type:

Article

Troglitazone Improves Ovulation and Hirsutism in the Polycystic Ovary Syndrome: A Multicenter, Double Blind, Placebo-Controlled Trial.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 4, p. 1626, doi. 10.1210/jcem.86.4.7375

By:

AZZIZ, RICARDO;
EHRMANN, DAVID;
LEGRO, RICHARD S.;
WHITCOMB, RANDALL W.;
HANLEY, ROCHELLE;
FERESHETIAN, ANITA GMEREK;
O’KEEFE, MARY;
GHAZZI, MAHMOUD N.

Publication type:

Article

Polycystic Ovary Syndrome Is Associated with Obstructive Sleep Apnea and Daytime Sleepiness: Role of Insulin Resistance.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 2, p. 517, doi. 10.1210/jcem.86.2.7185

By:

VGONTZAS, ALEXANDROS N.;
LEGRO, RICHARD S.;
BIXLER, EDWARD O.;
GRAYEV, ALLISON;
KALES, ANTHONY;
CHROUSOS, GEORGE P.

Publication type:

Article

Allelic Variants of the Follistatin Gene in Polycystic Ovary Syndrome.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2000, v. 85, n. 12, p. 4455, doi. 10.1210/jcem.85.12.7026

By:

URBANEK, MARGRIT;
XINQI WU;
VICKERY, KATHRYN R.;
LEE-CHUAN KAO;
CHRISTENSON, LANE K.;
SCHNEYER, ALAN;
LEGRO, RICHARD S.;
DRISCOLL, DEBORAH A.;
STRAUSS, JEROME F.;
DUNAIF, ANDREA;
SPIELMAN, RICHARD S.

Publication type:

Article

Rapid Maturation of the Reproductive Axis during Perimenarche Independent of Body Composition.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2000, v. 85, n. 3, p. 1021, doi. 10.1210/jcem.85.3.6423

By:

LEGRO, RICHARD S.;
HUNG MO LIN;
DEMERS, LAURENCE M.;
LLOYD, TOM

Publication type:

Article

Comment on "Prevalence and Predictors of Risk for Type 2 Diabetes Mellitus and Impaired Glucose Tolerance in Polycystic Ovary Syndrome".

Published in:

Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 8, p. 2974, doi. 10.1210/jcem.84.8.5939-4

By:

Dunaif, Andrea;
Legro, Richard S.

Publication type:

Article

Prevalence and Predictors of Risk for Type 2 Diabetes Mellitus and Impaired Glucose Tolerance in Polycystic Ovary Syndrome: A Prospective, Controlled Study in 254 Affected Women*.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 1, p. 165, doi. 10.1210/jcem.84.1.5393

By:

LEGRO, RICHARD S.;
KUNSELMAN, ALLEN R.;
DODSON, WILLIAM C.;
DUNAIF, ANDREA

Publication type:

Article

Reproductive Life Planning and Contraceptive Action Planning for Privately Insured Women: The MyNewOptions Study.

Published in:

Perspectives on Sexual & Reproductive Health, 2019, v. 51, n. 4, p. 219, doi. 10.1363/psrh.12123

By:

Chuang, Cynthia H.;
Weisman, Carol S.;
Velott, Diana L.;
Lehman, Erik;
Chinchilli, Vernon M.;
Francis, Erica B.;
Moos, Merry‐K.;
Sciamanna, Christopher N.;
Armitage, Christopher J.;
Legro, Richard S.

Publication type:

Article

Effect of Incorporating 1 Avocado per Day Versus Habitual Diet on Vascular Function in Adults With Abdominal Obesity: An Ancillary Study of HAT, a Randomized Controlled Trial.

Published in:

Journal of the American Heart Association, 2024, v. 13, n. 10, p. 1, doi. 10.1161/JAHA.123.030497

By:

Davis, Kristin M.;
Petersen, Kristina S.;
Matthan, Nirupa R.;
Legro, Richard S.;
Kris-Etherton, Penny M.

Publication type:

Article

Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial.

Published in:

2022

By:

Lichtenstein, Alice H.;
Kris-Etherton, Penny M.;
Petersen, Kristina S.;
Matthan, Nirupa R.;
Barnes, Samuel;
Vitolins, Mara Z.;
Zhaoping Li;
Sabaté, Joan;
Rajaram, Sujatha;
Chowdhury, Shilpy;
Davis, Kristin M.;
Galluccio, Jean;
Gilhooly, Cheryl H.;
Legro, Richard S.;
Li, Jason;
Lovato, Laura;
Perdue, Letitia H.;
Petty, Gayle;
Rasmussen, Anna M.;
Segovia-Siapco, Gina

Publication type:

journal article

Proactively Establishing a Biologic Specimens Repository for Large Clinical Trials: An Idea Whose Time has Come.

Published in:

Systems Biology in Reproductive Medicine, 2011, v. 57, n. 5, p. 217, doi. 10.3109/19396368.2011.604818

By:

Casson, Peter R.;
Krawetz, Stephen A.;
Diamond, Michael P.;
Zhang, Heping;
Legro, Richard S.;
Schlaff, William D.;
Coutifaris, Christos;
Brzyski, Robert G.;
Christman, Gregory M.;
Santoro, Nanette;
Eisenberg, Esther

Publication type:

Article

Establishing a Biologic Specimens Repository for Reproductive Clinical Trials: Technical Aspects.

Published in:

Systems Biology in Reproductive Medicine, 2011, v. 57, n. 5, p. 222, doi. 10.3109/19396368.2011.604819

By:

Krawetz, Stephen A.;
Casson, Peter R.;
Diamond, Michael P.;
Zhang, Heping;
Legro, Richard S.;
Schlaff, William D.;
Coutifaris, Christos;
Brzyski, Robert G.;
Christman, Gregory M.;
Santoro, Nanette;
Eisenberg, Esther

Publication type:

Article

Maternal and infant health during the COVID-19 pandemic – A Pennsylvania Study Protocol.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0323891

By:

Sznajder, Kristin K.;
Legro, Richard S.;
Teti, Douglas;
Mackeen, A. Dhanya;
Mulla, Wadia;
Simhan, Hyagriv;
Hwang, Wenke

Publication type:

Article

Effect of Preconception Impaired Glucose Tolerance on Pregnancy Outcomes in Women With Polycystic Ovary Syndrome.

Published in:

2017

By:

Wei, Daimin;
Zhang, Bo;
Shi, Yuhua;
Zhang, Lin;
Zhao, Shigang;
Du, Yanzhi;
Xu, Lizhen;
Legro, Richard S;
Zhang, Heping;
Chen, Zi-Jiang

Publication type:

journal article

Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome .

Published in:

Journal of Clinical Endocrinology & Metabolism, 2017, v. 102, n. 8, p. 2862, doi. 10.1210/jc.2017-00612

By:

Gorsic, Lidija K.;
Kosova, Gulum;
Werstein, Brian;
Sisk, Ryan;
Legro, Richard S.;
Hayes, M. Geoffrey;
Teixeira, Jose M.;
Dunaif, Andrea;
Urbanek, Margrit

Publication type:

Article