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Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition.
Published in:
Cancer & Metabolism, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40170-023-00318-y
By:
- Holt, Amy K.;
- Najumudeen, Arafath K.;
- Collard, Tracey J.;
- Li, Hao;
- Millett, Laura M.;
- Hoskin, Ashley J.;
- Legge, Danny N.;
- Mortensson, Eleanor M. H.;
- Flanagan, Dustin J.;
- Jones, Nicholas;
- Kollareddy, Madhu;
- Timms, Penny;
- Hitchings, Matthew D.;
- Cronin, James;
- Sansom, Owen J.;
- Williams, Ann C.;
- Vincent, Emma E.
Publication type:
Article
Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.
Published in:
PLoS Genetics, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.pgen.1009525
By:
- Gormley, Mark;
- Yarmolinsky, James;
- Dudding, Tom;
- Burrows, Kimberley;
- Martin, Richard M.;
- Thomas, Steven;
- Tyrrell, Jessica;
- Brennan, Paul;
- Pring, Miranda;
- Boccia, Stefania;
- Olshan, Andrew F.;
- Diergaarde, Brenda;
- Hung, Rayjean J.;
- Liu, Geoffrey;
- Legge, Danny;
- Tajara, Eloiza H.;
- Severino, Patricia;
- Lacko, Martin;
- Ness, Andrew R.;
- Davey Smith, George
Publication type:
Article
The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor.
Published in:
Molecular Oncology, 2022, v. 16, n. 3, p. 630, doi. 10.1002/1878-0261.13101
By:
- Legge, Danny;
- Li, Ling;
- Moriarty, Whei;
- Lee, David;
- Szemes, Marianna;
- Zahed, Asef;
- Panousopoulos, Leonidas;
- Chung, Wan Yun;
- Aghabi, Yara;
- Barratt, Jasmin;
- Williams, Richard;
- Pritchard‐Jones, Kathy;
- Malik, Karim T.A.;
- Oltean, Sebastian;
- Brown, Keith W.
Publication type:
Article
Identifying metabolic features of colorectal cancer liability using Mendelian randomization.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.87894
By:
- Bull, Caroline;
- Hazelwood, Emma;
- Bell, Joshua A.;
- Tan, Vanessa;
- Constantinescu, Andrei-Emil;
- Borges, Carolina;
- Legge, Danny;
- Burrows, Kimberley;
- Huyghe, Jeroen R.;
- Brenner, Hermann;
- Castellvi-Bel, Sergi;
- Chan, Andrew T.;
- Sun-Seog Kweon;
- Le Marchand, Loic;
- Li Li;
- Cheng, Iona;
- Pai, Rish K.;
- Figueiredo, Jane C.;
- Murphy, Neil;
- Gunter, Marc J.
Publication type:
Article
The role of B-Cell Lymphoma-3 (BCL-3) in enabling the hallmarks of cancer: implications for the treatment of colorectal carcinogenesis.
Published in:
Carcinogenesis, 2020, v. 41, n. 3, p. 249, doi. 10.1093/carcin/bgaa003
By:
- Legge, Danny N;
- Chambers, Adam C;
- Parker, Christopher T;
- Timms, Penny;
- Collard, Tracey J;
- Williams, Ann C
Publication type:
Article
Evaluating the effect of metabolic traits on oral and oropharyngeal cancer risk using Mendelian randomization.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.82674
By:
- Gormley, Mark;
- Dudding, Tom;
- Thomas, Steven J.;
- Tyrrell, Jessica;
- Ness, Andrew R.;
- Pring, Miranda;
- Legge, Danny;
- Smith, George Davey;
- Richmond, Rebecca C.;
- Vincent, Emma E.;
- Bull, Caroline
Publication type:
Article
5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis.
Published in:
2021
By:
- Dixon, Steven William;
- Collard, Tracey Jane;
- Mortensson, Eleanor May Harrisdotter;
- Legge, Danny Nigel;
- Chambers, Adam Christian;
- Greenhough, Alexander;
- Creed, Tom Julian;
- Williams, Ann Caroline
Publication type:
journal article
In-silico and in-vitro morphometric analysis of intestinal organoids.
Published in:
PLoS Computational Biology, 2023, v. 19, n. 8, p. 1, doi. 10.1371/journal.pcbi.1011386
By:
- Montes-Olivas, Sandra;
- Legge, Danny;
- Lund, Abbie;
- Fletcher, Alexander G.;
- Williams, Ann C.;
- Marucci, Lucia;
- Homer, Martin
Publication type:
Article

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