Works by Lefkowitz, Martin

Results: 79
    1

    Effects of sacubitril/valsartan according to background beta‐blocker therapy in patients with heart failure and reduced ejection fraction: Insights from PARADIGM‐HF.

    Published in:
    European Journal of Heart Failure, 2025, v. 27, n. 5, p. 779, doi. 10.1002/ejhf.3515
    By:
    • Gupta, Sharmistha Datta;
    • Butt, Jawad H.;
    • McMurray, Eoghan G.M.;
    • Talebi, Atefeh;
    • Matsumoto, Shingo;
    • Rizkala, Adel R.;
    • Henderson, Alasdair D.;
    • Desai, Akshay S.;
    • Lefkowitz, Martin;
    • Packer, Milton;
    • Rouleau, Jean L.;
    • Solomon, Scott D.;
    • Swedberg, Karl;
    • Zile, Michael R.;
    • Jhund, Pardeep S.;
    • McMurray, John J.V.
    Publication type:
    Article
    2

    Near-universal prevalence of central adiposity in heart failure with preserved ejection fraction: the PARAGON-HF trial Open Access.

    Published in:
    European Heart Journal, 2025, v. 46, n. 25, p. 2372, doi. 10.1093/eurheartj/ehaf057
    By:
    • Peikert, Alexander;
    • Vaduganathan, Muthiah;
    • Claggett, Brian L;
    • Kulac, Ian J;
    • Litwin, Sheldon;
    • Zile, Michael;
    • Desai, Akshay S;
    • Jhund, Pardeep S;
    • Butt, Jawad H;
    • Lam, Carolyn S P;
    • Martinez, Felipe;
    • Veldhuisen, Dirk J Van;
    • Zannad, Faiez;
    • Rouleau, Jean;
    • Lefkowitz, Martin;
    • McMurray, John J V;
    • Solomon, Scott D;
    • Packer, Milton
    Publication type:
    Article
    3
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    Geographic variations in the PARADIGM-HF heart failure trial.

    Published in:
    European Heart Journal, 2016, v. 37, n. 41, p. 3167, doi. 10.1093/eurheartj/ehw226
    By:
    • Kristensen, Søren Lund;
    • Martinez, Felipe;
    • Jhund, Pardeep S.;
    • Arango, Juan Luis;
    • Bĕlohlávek, Jan;
    • Boytsov, Sergey;
    • Cabrera, Walter;
    • Gomez, Efrain;
    • Hagège, Albert A.;
    • Jun Huang;
    • Kiatchoosakun, Songsak;
    • Kee-Sik Kim;
    • Mendoza, Iván;
    • Senni, Michele;
    • Squire, Iain B.;
    • Vinereanu, Dragos;
    • Ching-Chiew Wong, Raymond;
    • Jianjian Gong;
    • Lefkowitz, Martin P.;
    • Rizkala, Adel R.
    Publication type:
    Article
    5

    Efficacy and safety of LCZ696 (sacubitrilvalsartan) according to age: insights from PARADIGM-HF.

    Published in:
    European Heart Journal, 2015, v. 36, n. 38, p. 2576, doi. 10.1093/eurheartj/ehv330
    By:
    • Jhund, Pardeep S.;
    • Fu, Michael;
    • Bayram, Edmundo;
    • Chen, Chen-Huan;
    • Negrusz-Kawecka, Marta;
    • Rosenthal, Arvo;
    • Desai, Akshay S.;
    • Lefkowitz, Martin P.;
    • Rizkala, Adel R.;
    • Rouleau, Jean L.;
    • Shi, Victor C.;
    • Solomon, Scott D.;
    • Swedberg, Karl;
    • Zile, Michael R.;
    • McMurray, John J. V.;
    • Packer, Milton
    Publication type:
    Article
    6

    Effect of the angiotensin-receptor-neprilysin inhibitor LCZ696 compared with enalapril on mode of death in heart failure patients.

    Published in:
    European Heart Journal, 2015, v. 36, n. 30, p. 1990, doi. 10.1093/eurheartj/ehv186
    By:
    • Desai, Akshay S.;
    • McMurray, John J. V.;
    • Packer, Milton;
    • Swedberg, Karl;
    • Rouleau, Jean L.;
    • Fabian Chen;
    • Jianjian Gong;
    • Rizkala, Adel R.;
    • Brahimi, Abdel;
    • Claggett, Brian;
    • Finn, Peter V.;
    • Hartley, Loren Howard;
    • Jiankang Liu;
    • Lefkowitz, Martin;
    • Victor Shi;
    • Zile, Michael R.;
    • Solomon, Scott D.
    Publication type:
    Article
    7

    A putative placebo analysis of the effects of LCZ696 on clinical outcomes in heart failure.

    Published in:
    European Heart Journal, 2015, v. 36, n. 7, p. 434
    By:
    • McMurray, John;
    • Packer, Milton;
    • Desai, Akshay;
    • Gong, Jianjian;
    • Greenlaw, Nicola;
    • Lefkowitz, Martin;
    • Rizkala, Adel;
    • Shi, Victor;
    • Rouleau, Jean;
    • Solomon, Scott;
    • Swedberg, Karl;
    • Zile, Michael R.;
    • Andersen, Karl;
    • Arango, Juan Luis;
    • Arnold, Malcolm;
    • Be˘lohlávek, Jan;
    • Böhm, Michael;
    • Boytsov, Sergey;
    • Burgess, Lesley;
    • Cabrera, Walter
    Publication type:
    Article
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    Effects of sacubitril/valsartan on glycemia in patients with diabetes and heart failure: the PARAGON-HF and PARADIGM-HF trials.

    Published in:
    Cardiovascular Diabetology, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12933-022-01545-1
    By:
    • Wijkman, Magnus O.;
    • Claggett, Brian;
    • Vaduganathan, Muthiah;
    • Cunningham, Jonathan W.;
    • Rørth, Rasmus;
    • Jackson, Alice;
    • Packer, Milton;
    • Zile, Michael;
    • Rouleau, Jean;
    • Swedberg, Karl;
    • Lefkowitz, Martin;
    • Shah, Sanjiv J.;
    • Pfeffer, Marc A.;
    • McMurray, John J. V.;
    • Solomon, Scott D.
    Publication type:
    Article
    12
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    Centrally adjudicated vs. investigator-reported outcomes in randomized heart failure trials.

    Published in:
    European Heart Journal, 2024, v. 45, n. 47, p. 5087, doi. 10.1093/eurheartj/ehae753
    By:
    • Wandel, Simon;
    • Desai, Akshay S;
    • Chen, Chien-Wei;
    • McMurray, John J V;
    • Packer, Milton;
    • Solomon, Scott D;
    • Pfeffer, Marc A;
    • Felker, G Michael;
    • Zannad, Faiez;
    • Petrie, Mark C;
    • Jhund, Pardeep S;
    • Attari, Zenab;
    • Mueller-Velten, Guenther;
    • Lefkowitz, Martin;
    • Soergel, David;
    • Gimpelewicz, Claudio
    Publication type:
    Article
    14

    Sacubitril/valsartan in heart failure with mildly reduced or preserved ejection fraction: a pre-specified participant-level pooled analysis of PARAGLIDE-HF and PARAGON-HF.

    Published in:
    European Heart Journal, 2023, v. 44, n. 31, p. 2982, doi. 10.1093/eurheartj/ehad344
    By:
    • Vaduganathan, Muthiah;
    • Mentz, Robert J;
    • Claggett, Brian L;
    • Miao, Zi Michael;
    • Kulac, Ian J;
    • Ward, Jonathan H;
    • Hernandez, Adrian F;
    • Morrow, David A;
    • Starling, Randall C;
    • Velazquez, Eric J;
    • Williamson, Kristin M;
    • Desai, Akshay S;
    • Zieroth, Shelley;
    • Lefkowitz, Martin;
    • McMurray, John J V;
    • Braunwald, Eugene;
    • Solomon, Scott D
    Publication type:
    Article
    15

    Importance of cystatin C in estimating glomerular filtration rate: the PARADIGM-HF trial.

    Published in:
    European Heart Journal, 2023, v. 44, n. 24, p. 2202, doi. 10.1093/eurheartj/ehad210
    By:
    • Tolomeo, Paolo;
    • Butt, Jawad H;
    • Kondo, Toru;
    • Campo, Gianluca;
    • Desai, Akshay S;
    • Jhund, Pardeep S;
    • Køber, Lars;
    • Lefkowitz, Martin P;
    • Rouleau, Jean L;
    • Solomon, Scott D;
    • Swedberg, Karl;
    • Vaduganathan, Muthiah;
    • Zile, Michael R;
    • Packer, Milton;
    • McMurray, John J V
    Publication type:
    Article
    16

    Effect of sacubitril/valsartan on investigator-reported ventricular arrhythmias in PARADIGM-HF.

    Published in:
    European Journal of Heart Failure. Supplements, 2022, v. 24, n. 3, p. 551, doi. 10.1002/ejhf.2419
    By:
    • Curtain, James P.;
    • Jackson, Alice M.;
    • Li Shen;
    • Jhund, Pardeep S.;
    • Docherty, Kieran F.;
    • Petrie, Mark C.;
    • Castagno, Davide;
    • Desai, Akshay S.;
    • Rohde, Luis E.;
    • Lefkowitz, Martin P.;
    • Rouleau, Jean-Lucien;
    • Zile, Michael R.;
    • Solomon, Scott D.;
    • Swedberg, Karl;
    • Packer, Milton;
    • McMurray, John J. V.
    Publication type:
    Article
    17

    Diabetes and pre-diabetes in patients with heart failure and preserved ejection fraction.

    Published in:
    European Journal of Heart Failure. Supplements, 2022, v. 24, n. 3, p. 497, doi. 10.1002/ejhf.2403
    By:
    • Jackson, Alice M.;
    • Rørth, Rasmus;
    • Jiankang Liu;
    • Kristensen, Søren Lund;
    • Anand, Inder S.;
    • Claggett, Brian L.;
    • Cleland, John G. F.;
    • Chopra, Vijay K.;
    • Desai, Akshay S.;
    • Junbo Ge;
    • Jianjian Gong;
    • Lam, Carolyn S. P.;
    • Lefkowitz, Martin P.;
    • Maggioni, Aldo P.;
    • Martinez, Felipe;
    • Packer, Milton;
    • Pfeffer, Marc A.;
    • Pieske, Burkert;
    • Redfield, Margaret M.;
    • Rizkala, Adel R.
    Publication type:
    Article
    18

    New medicinal products for chronic heart failure: advances in clinical trial design and efficacy assessment.

    Published in:
    European Journal of Heart Failure. Supplements, 2017, v. 19, n. 6, p. 718, doi. 10.1002/ejhf.809
    By:
    • Cowie, Martin R.;
    • Filippatos, Gerasimos S.;
    • de los Angeles Alonso Garcia, Maria;
    • Anker, Stefan D.;
    • Baczynska, Anna;
    • Bloomfield, Daniel M.;
    • Borentain, Maria;
    • Slot, Karsten Bruins;
    • Cronin, Maureen;
    • Doevendans, Pieter A.;
    • El-Gazayerly, Amany;
    • Gimpelewicz, Claudio;
    • Honarpour, Narimon;
    • Janmohamed, Salim;
    • Janssen, Heidi;
    • Kim, Albert M.;
    • Lautsch, Dominik;
    • Laws, Ian;
    • Lefkowitz, Martin;
    • Lopez-Sendon, Jose
    Publication type:
    Article
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    Prognostic Significance of Nutritional Scores in Patients With Heart Failure: Insights From the PARAGON-HF Trial.

    Published in:
    Journal of the American Heart Association, 2025, v. 14, n. 9, p. 1, doi. 10.1161/JAHA.124.038872
    By:
    • Lu, Henri;
    • Claggett, Brian L.;
    • Masatoshi Minamisawa;
    • Ostrominski, John W.;
    • Foà, Alberto;
    • Pabón, Maria A.;
    • Kalayci, Arzu;
    • Vaduganathan, Muthiah;
    • Cikes, Maja;
    • Shah, Amil M.;
    • Desai, Akshay S.;
    • McMurray, John J. V.;
    • Jhund, Pardeep S.;
    • Packer, Milton;
    • Lefkowitz, Martin;
    • Rouleau, Jean L.;
    • Zile, Michael R.;
    • Zannad, Faiez;
    • Hegde, Sheila M.;
    • Solomon, Scott D.
    Publication type:
    Article
    24

    Comprehensive Analysis of the Effects of Sacubitril/Valsartan According to Sex Among Patients With Heart Failure and Reduced Ejection Fraction in PARADIGM-HF.

    Published in:
    Journal of the American Heart Association, 2025, v. 14, n. 9, p. 1, doi. 10.1161/JAHA.124.038249
    By:
    • Chimura, Misato;
    • Butt, Jawad H.;
    • Matsumoto, Shingo;
    • McMurray, Eoghan G. M.;
    • Henderson, Alasdair D.;
    • Talebi, Atefeh;
    • Desai, Akshay S.;
    • Lefkowitz, Martin P.;
    • Rizkala, Adel R.;
    • Rouleau, Jean L.;
    • Solomon, Scott D.;
    • Swedberg, Karl;
    • Zile, Michael R.;
    • Packer, Milton;
    • Jhund, Pardeep S.;
    • McMurray, John J. V.
    Publication type:
    Article
    25

    Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Proteomic Substudy.

    Published in:
    Journal of the American Heart Association, 2024, v. 13, n. 13, p. 1, doi. 10.1161/JAHA.123.033544
    By:
    • Patel-Murray, Natasha L.;
    • Luqing Zhang;
    • Claggett, Brian L.;
    • Dongchu Xu;
    • Serrano-Fernandez, Pablo;
    • Healey, Margaret;
    • Wandel, Simon;
    • Chien-Wei Chen;
    • Jacob, Jaison;
    • Huilei Xu;
    • Turner, Gordon M.;
    • Chutkow, William;
    • Yates, Denise P.;
    • O'Donnell, Christopher J.;
    • Prescott, Margaret F.;
    • Lefkowitz, Martin;
    • Gimpelewicz, Claudio R.;
    • Beste, Michael T.;
    • Zhao, Faye;
    • Liangke Gou
    Publication type:
    Article
    26

    Impact of Chronic Obstructive Pulmonary Disease in Patients With Heart Failure With Preserved Ejection Fraction: Insights From PARAGON-HF.

    Published in:
    2021
    By:
    • Mooney, Leanne;
    • Hawkins, Nathaniel M.;
    • Jhund, Pardeep S.;
    • Redfield, Margaret M.;
    • Vaduganathan, Muthiah;
    • Desai, Akshay S.;
    • Rouleau, Jean L.;
    • Masatoshi Minamisawa;
    • Shah, Amil M.;
    • Lefkowitz, Martin P.;
    • Zile, Michael R.;
    • Van Veldhuisen, Dirk J.;
    • Pfeffer, Marc A.;
    • Anand, Inder S.;
    • Maggioni, Aldo P.;
    • Senni, Michele;
    • Claggett, Brian L.;
    • Solomon, Scott D.;
    • McMurray, John J. V.;
    • Minamisawa, Masatoshi
    Publication type:
    journal article
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    Clinical Characteristics and Outcomes of Patients With Heart Failure With Reduced Ejection Fraction and Chronic Obstructive Pulmonary Disease: Insights From PARADIGM-HF.

    Published in:
    2021
    By:
    • Ehteshami-Afshar, Solmaz;
    • Mooney, Leanne;
    • Dewan, Pooja;
    • Desai, Akshay S.;
    • Lang, Ninian N.;
    • Lefkowitz, Martin P.;
    • Petrie, Mark C.;
    • Rizkala, Adel R.;
    • Rouleau, Jean L.;
    • Solomon, Scott D.;
    • Swedberg, Karl;
    • Shi, Victor C.;
    • Zile, Michael R.;
    • Packer, Milton;
    • McMurray, John J. V.;
    • Jhund, Pardeep S.;
    • Hawkins, Nathaniel M.
    Publication type:
    journal article
    29
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    Exceptional early blood pressure control rates: The ACCOMPLISH trial.

    Published in:
    Blood Pressure, 2007, v. 16, n. 2, p. 80, doi. 10.1080/08037050701395571
    By:
    • Jamerson, Kenneth;
    • Bakris, George L.;
    • Dahlöf, Björn;
    • Pitt, Bertram;
    • Velazquez, Eric;
    • Gupte, Jitendra;
    • Lefkowitz, Martin;
    • Hester, Allen;
    • Shi, Victor;
    • Kjeldsen, Sverre E.;
    • Cushman, William;
    • Papademetriou, Vasilios;
    • Weber, Michael
    Publication type:
    Article
    31

    Baseline characteristics in the Avoiding Cardiovascular events through Combination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: A hypertensive population at high cardiovascular risk.

    Published in:
    Blood Pressure, 2007, v. 16, n. 1, p. 13, doi. 10.1080/08037050701217643
    By:
    • Weber, Michael A.;
    • Bakris, George L.;
    • Dahlöf, Björn;
    • Pitt, Bertram;
    • Velazquez, Eric;
    • Gupte, Jitendra;
    • Lefkowitz, Martin;
    • Hester, Allen;
    • Shi, Victor;
    • Weir, Matthew;
    • Kjeldsen, Sverre;
    • Massie, Barry;
    • Nesbitt, Shawna;
    • Ofili, Elizabeth;
    • Jamerson, Kenneth;
    • for the Accomplish Investigators
    Publication type:
    Article
    32

    Conference Highlights.

    Published in:
    American Family Physician, 2001, v. 64, n. 4, p. 657
    By:
    • Chatfield, Joanne E.;
    • Lefkowitz, Martin P.;
    • Mallick, Rajiv;
    • Katz, Nathanial;
    • Nickel, J. Curtis;
    • Bensch, George
    Publication type:
    Article
    33

    Intracranial metastases in prostate cancer.

    Published in:
    1984
    By:
    • Taylor, H. Grant;
    • Lefkowitz, Martin;
    • Coggin, Julian T.;
    • Skoog, Steven J.;
    • Miles, Brian J.;
    • McLeod, David G.;
    • Taylor, H G;
    • Lefkowitz, M;
    • Skoog, S J;
    • Miles, B J;
    • McLeod, D G;
    • Coggin, J T
    Publication type:
    journal article
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    Rationale and design of the avoiding cardiovascular events through combination therapy in patients living with systolic hypertension (ACCOMPLISH) trial: The first randomized controlled trial to compare the clinical outcome effects of first-line combination therapies in hypertension

    Published in:
    American Journal of Hypertension, 2004, v. 17, n. 9, p. 793, doi. 10.1016/j.amjhyper.2004.05.004
    By:
    • Jamerson, Kenneth A.;
    • Bakris, George L.;
    • Wun, Chuan-Chuan;
    • Dahlöf, Björn;
    • Lefkowitz, Martin;
    • Manfreda, Sheryl;
    • Pitt, Bertram;
    • Velazquez, Eric J.;
    • Weber, Michael A.
    Publication type:
    Article
    38

    Antihypertensive therapy and quality of life.

    Published in:
    American Journal of Hypertension, 1996, v. 9, n. 9, p. 854, doi. 10.1016/S0895-7061(96)00116-1
    By:
    • Weir, Matthew R.;
    • Prisant, L.Michael;
    • Papademetriou, Vasilios;
    • Weber, Michael A.;
    • Adegbile, Isaac A.;
    • Alemayehu, Demissie;
    • Lefkowitz, Martin P.
    Publication type:
    Article
    39
    40

    Naked megakaryocyte nuclei. A clue to malignancy.

    Published in:
    Cancer (0008543X), 1977, v. 40, n. 4, p. 1497, doi. 10.1002/1097-0142(197710)40:4<1497::AID-CNCR2820400421>3.0.CO;2-C
    By:
    • Lefkowitz, Martin;
    • Lefkowitz, Estelle
    Publication type:
    Article
    41
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    Cardiovascular‐kidney‐metabolic overlap in heart failure with preserved ejection fraction: Cardiac structure and function, clinical outcomes, and response to sacubitril/valsartan in PARAGON‐HF.

    Published in:
    European Journal of Heart Failure, 2024, v. 26, n. 8, p. 1762, doi. 10.1002/ejhf.3304
    By:
    • Lassen, Mats C.H.;
    • Ostrominski, John W.;
    • Claggett, Brian L.;
    • Packer, Milton;
    • Zile, Michael;
    • Desai, Akshay S.;
    • Shah, Amil M.;
    • Cikes, Maja;
    • Merkely, Bela;
    • Gori, Mauro;
    • Wang, Xiaowen;
    • Hegde, Sheila M.;
    • Pfeffer, Marc A.;
    • Lefkowitz, Martin;
    • McMurray, John J.V.;
    • Solomon, Scott D.;
    • Vaduganathan, Muthiah
    Publication type:
    Article
    44

    Effects of sacubitril/valsartan according to polypharmacy status in PARAGON‐HF.

    Published in:
    European Journal of Heart Failure, 2024, v. 26, n. 5, p. 1125, doi. 10.1002/ejhf.3223
    By:
    • Matsumoto, Shingo;
    • Yang, Mingming;
    • Shen, Li;
    • Henderson, Alasdair;
    • Claggett, Brian L.;
    • Desai, Akshay S.;
    • Lefkowitz, Martin;
    • Rouleau, Jean L.;
    • Vardeny, Orly;
    • Zile, Michael R.;
    • Jhund, Pardeep S.;
    • Vaduganathan, Muthiah;
    • Solomon, Scott D.;
    • McMurray, John J.V.
    Publication type:
    Article
    45
    46

    Incremental prognostic value of biomarkers in PARADIGM‐HF.

    Published in:
    European Journal of Heart Failure, 2023, v. 25, n. 8, p. 1406, doi. 10.1002/ejhf.2887
    By:
    • McDowell, Kirsty;
    • Campbell, Ross;
    • Simpson, Joanne;
    • Cunningham, Jonathan W.;
    • Desai, Akshay S.;
    • Jhund, Pardeep S.;
    • Lefkowitz, Martin P.;
    • Rouleau, Jean L.;
    • Swedberg, Karl;
    • Zile, Michael R.;
    • Solomon, Scott D.;
    • Packer, Milton;
    • McMurray, John J.V.
    Publication type:
    Article
    47
    48

    Health‐related quality of life outcomes in PARAGON‐HF.

    Published in:
    European Journal of Heart Failure, 2022, v. 24, n. 12, p. 2264, doi. 10.1002/ejhf.2738
    By:
    • Chandra, Alvin;
    • Polanczyk, Carisi A.;
    • Claggett, Brian L.;
    • Vaduganathan, Muthiah;
    • Packer, Milton;
    • Lefkowitz, Martin P.;
    • Rouleau, Jean L.;
    • Liu, Jiankang;
    • Shi, Victor C.;
    • Schwende, Heike;
    • Zile, Michael R.;
    • Desai, Akshay S.;
    • Pfeffer, Marc A.;
    • McMurray, John J.V.;
    • Solomon, Scott D.;
    • Lewis, Eldrin F.
    Publication type:
    Article
    49
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    Angiotensin–neprilysin inhibition and renal outcomes across the spectrum of ejection fraction in heart failure.

    Published in:
    European Journal of Heart Failure, 2022, v. 24, n. 9, p. 1591, doi. 10.1002/ejhf.2421
    By:
    • Mc Causland, Finnian R.;
    • Lefkowitz, Martin P.;
    • Claggett, Brian;
    • Packer, Milton;
    • Senni, Michele;
    • Gori, Mauro;
    • Jhund, Pardeep S.;
    • McGrath, Martina M.;
    • Rouleau, Jean L.;
    • Shi, Victor;
    • Swedberg, Karl;
    • Vaduganathan, Muthiah;
    • Zannad, Faiez;
    • Pfeffer, Marc A.;
    • Zile, Michael;
    • McMurray, John J.V.;
    • Solomon, Scott D.
    Publication type:
    Article