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Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 12, p. 6704, doi. 10.3390/ijms25126704
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- Article
Novel inhibitory effect of galectin-3 on the respiratory burst induced by Staphylococcus aureus in human neutrophils.
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- Glycobiology, 2023, v. 33, n. 6, p. 503, doi. 10.1093/glycob/cwad032
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- Article
Safety and pharmacokinetics of GB1211, an oral galectin-3 inhibitor: a single- and multiple-dose first-in-human study in healthy participants.
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- Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 3, p. 267, doi. 10.1007/s00280-023-04513-y
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- Article
Increased Galectin-9 Levels Correlate with Disease Activity in Patients with DMARD-Naïve Rheumatoid Arthritis and Modulate the Secretion of MCP-1 and IL-6 from Synovial Fibroblasts.
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- Cells (2073-4409), 2023, v. 12, n. 2, p. 327, doi. 10.3390/cells12020327
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- Article
Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation.
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- Frontiers in Pharmacology, 2022, v. 10, p. 1, doi. 10.3389/fphar.2022.949264
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- Article
Galectin-3 Decreases 4-1BBL Bioactivity by Crosslinking Soluble and Membrane Expressed 4-1BB.
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- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.915890
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- Article
Site‐specific N‐glycan profiles of α<sub>5</sub>β<sub>1</sub> integrin from rat liver.
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- Biology of the Cell (Wiley-Blackwell), 2022, v. 114, n. 6, p. 160, doi. 10.1111/boc.202200017
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- Article
Selective Galectin‐8N Ligands: The Design and Synthesis of Phthalazinone‐d‐Galactals.
- Published in:
- ChemMedChem, 2022, v. 17, n. 6, p. 1, doi. 10.1002/cmdc.202100575
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- Article
Engineering the Ligand Specificity of the Human Galectin‐1 by Incorporation of Tryptophan Analogues.
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- ChemBioChem, 2022, v. 23, n. 5, p. 1, doi. 10.1002/cbic.202100593
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- Article
Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside.
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- ChemMedChem, 2022, v. 17, n. 3, p. 1, doi. 10.1002/cmdc.202100514
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- Article
Front Cover: Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside (ChemMedChem 3/2022)
- Published in:
- ChemMedChem, 2022, v. 17, n. 3, p. 1, doi. 10.1002/cmdc.202200044
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- Publication type:
- Article
Front Cover: Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside (ChemMedChem 3/2022).
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- ChemMedChem, 2022, v. 17, n. 3, p. 1, doi. 10.1002/cmdc.202100514
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- Publication type:
- Article
Chemokines modulate glycan binding and the immunoregulatory activity of galectins.
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- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02922-4
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- Article
Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression.
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- Gastric Cancer, 2021, v. 24, n. 5, p. 1050, doi. 10.1007/s10120-021-01186-5
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- Article
Synthesis and Biological Studies of O3‐Aryl Galactosides as Galectin Inhibitors.
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- Helvetica Chimica Acta, 2021, v. 104, n. 2, p. 1, doi. 10.1002/hlca.202000220
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- Article
3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-Sites for High-Affinity and High-Selectivity Inhibition of Galectin-3.
- Published in:
- Molecules, 2019, v. 24, n. 24, p. 4554, doi. 10.3390/molecules24244554
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- Article
Structure and Energetics of Ligand–Fluorine Interactions with Galectin‐3 Backbone and Side‐Chain Amides: Insight into Solvation Effects and Multipolar Interactions.
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- ChemMedChem, 2019, v. 14, n. 16, p. 1528, doi. 10.1002/cmdc.201900293
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- Article
A Galactoside-Binding Protein Tricked into Binding Unnatural Pyranose Derivatives: 3-Deoxy-3-Methyl-Gulosides Selectively Inhibit Galectin-1.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 15, p. 3786, doi. 10.3390/ijms20153786
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- Article
Extracellular and intracellular small-molecule galectin-3 inhibitors.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-38497-8
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- Article
Galectin‐3 type‐C self‐association on neutrophil surfaces; The carbohydrate recognition domain regulates cell function.
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- Journal of Leukocyte Biology, 2018, v. 103, n. 2, p. 341, doi. 10.1002/JLB.3A0317-110R
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- Article
Monosaccharide Derivatives with Low‐Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine–Amide, Phenyl–Arginine, Sulfur–π, and Halogen Bond Interactions.
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- ChemMedChem, 2018, v. 13, n. 2, p. 133, doi. 10.1002/cmdc.201700744
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- Article
Perdeuteration, crystallization, data collection and comparison of five neutron diffraction data sets of complexes of human galectin-3C.
- Published in:
- Acta Crystallographica: Section D, Structural Biology, 2016, v. 72, n. 11, p. 1194, doi. 10.1107/S2059798316015540
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- Article
Galactose-amidine derivatives as selective antagonists of galectin-9.
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- Canadian Journal of Chemistry, 2016, v. 94, n. 11, p. 936, doi. 10.1139/cjc-2015-0598
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- Article
Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition.
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- ChemBioChem, 2016, v. 17, n. 18, p. 1759, doi. 10.1002/cbic.201600285
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- Article
Intra- and intermolecular interactions of human galectin-3: assessment by full-assignment-based NMR.
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- Glycobiology, 2016, v. 26, n. 8, p. 888, doi. 10.1093/glycob/cww021
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- Article
Erratum: Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3.
- Published in:
- Nature Communications, 2016, v. 7, n. 7, p. 12063, doi. 10.1038/ncomms12063
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- Publication type:
- Article
Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3.
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- Nature Communications, 2016, v. 7, n. 4, p. 11302, doi. 10.1038/ncomms11302
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- Article
Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3′-sulfo-lactose, and 2′-fucosyllactose.
- Published in:
- Scientific Reports, 2016, p. 20289, doi. 10.1038/srep20289
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- Article
Immunohistochemical Studies on Galectin Expression in Colectomised Patients with Ulcerative Colitis.
- Published in:
- BioMed Research International, 2016, v. 2016, p. 1, doi. 10.1155/2016/5989128
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- Article
Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens.
- Published in:
- FEBS Journal, 2015, v. 282, n. 17, p. 3348, doi. 10.1111/febs.13348
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- Article
Gal-3 regulates the capacity of dendritic cells to promote NKT-cell-induced liver injury.
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- European Journal of Immunology, 2015, v. 45, n. 2, p. 531, doi. 10.1002/eji.201444849
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- Article
The role of Galectin-3 in α-synuclein-induced microglial activation.
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- Acta Neuropathologica Communications, 2014, v. 2, n. 1, p. 1, doi. 10.1186/s40478-014-0156-0
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- Article
Synthesis of 1,2,3-triazole-linked galactohybrids and their inhibitory activities on galectins.
- Published in:
- ARKIVOC: Online Journal of Organic Chemistry, 2014, p. 90
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- Article
Ligand binding and complex formation of galectin-3 is modulated by pH variations.
- Published in:
- Biochemical Journal, 2014, v. 457, n. 1, p. 107, doi. 10.1042/BJ20130933
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- Article
Investigation into the Feasibility of Thioditaloside as a Novel Scaffold for Galectin-3-Specific Inhibitors.
- Published in:
- ChemBioChem, 2013, v. 14, n. 11, p. 1331, doi. 10.1002/cbic.201300245
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- Article
Galectin-3 deficiency protects pancreatic islet cells from cytokine-triggered apoptosis in vitro.
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- Journal of Cellular Physiology, 2013, v. 228, n. 7, p. 1568, doi. 10.1002/jcp.24318
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- Article
Glycosphingolipid composition of epithelial cells isolated along the villus axis of small intestine of a single human individual.
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- Glycobiology, 2012, v. 22, n. 12, p. 1721, doi. 10.1093/glycob/cws115
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- Publication type:
- Article
Galectin-8 in IgA Nephritis: Decreased Binding of IgA by Galectin-8 Affinity Chromatography and Associated Increased Binding in Non-IgA Serum Glycoproteins.
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- Journal of Clinical Immunology, 2012, v. 32, n. 2, p. 246, doi. 10.1007/s10875-011-9618-3
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- Article
Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3.
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- 2012
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- Publication type:
- journal article
Regulation of Transforming Growth Factor-β1--driven Lung Fibrosis by Galectin-3.
- Published in:
- American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 5, p. 537, doi. 10.1164/rccm.201106-0965OC
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- Article
Taloside Inhibitors of Galectin-1 and Galectin-3.
- Published in:
- Chemical Biology & Drug Design, 2012, v. 79, n. 3, p. 339, doi. 10.1111/j.1747-0285.2011.01283.x
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- Article
Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor.
- Published in:
- FEBS Journal, 2012, v. 279, n. 2, p. 193, doi. 10.1111/j.1742-4658.2011.08414.x
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- Article
Galectin-1-Binding Glycoforms of Haptoglobin with Altered Intracellular Trafficking, and Increase in Metastatic Breast Cancer Patients.
- Published in:
- PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026560
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- Publication type:
- Article
Arene-Anion Based Arginine-Binding Motif on a Galactose Scaffold: Structure-Activity Relationships of Interactions with Arginine-Rich Galectins.
- Published in:
- Chemistry - A European Journal, 2011, v. 17, n. 29, p. 8139, doi. 10.1002/chem.201003247
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- Article
Multimeric Lactoside 'Click Clusters' as Tools to Investigate the Effect of Linker Length in Specific Interactions with Peanut Lectin, Galectin-1, and -3.
- Published in:
- ChemBioChem, 2010, v. 11, n. 10, p. 1430, doi. 10.1002/cbic.201000167
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- Article
Galectin-3, a marker for vacuole lysis by invasive pathogens.
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- Cellular Microbiology, 2010, v. 12, n. 4, p. 530, doi. 10.1111/j.1462-5822.2009.01415.x
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- Article
Synthesis and Evaluation of New Thiodigalactoside-Based Chemical Probes to Label Galectin-3.
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- ChemBioChem, 2009, v. 10, n. 10, p. 1724, doi. 10.1002/cbic.200900198
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- Article
Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils.
- Published in:
- Glycobiology, 2009, v. 19, n. 1, p. 16
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- Publication type:
- Article
The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading.
- Published in:
- Glycobiology, 2009, v. 19, n. 1, p. 29, doi. 10.1093/glycob/cwn100
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- Article
The {beta}-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist
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- Glycobiology, 2008, v. 18, n. 11, p. 905, doi. 10.1093/glycob/cwn081
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- Article