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Patterns of emergency admission for IBD patients over the last 10 years in Lothian, Scotland: a retrospective prevalent cohort analysis.
Published in:
Alimentary Pharmacology & Therapeutics, 2022, v. 56, n. 1, p. 67, doi. 10.1111/apt.16867
By:
- Lyons, Mathew;
- Derikx, Lauranne A. A. P.;
- Fulforth, James;
- McCall, Sophie;
- Plevris, Nikolas;
- Jenkinson, Philip W.;
- Kirkwood, Kathryn;
- Siakavellas, Spyros;
- Lucaciu, Laura;
- Constantine‐Cooke, Nathan;
- Arnott, Ian D.;
- Henderson, Paul;
- Russell, Richard K.;
- Wilson, David C.;
- Lees, Charlie W.;
- Jones, Gareth‐Rhys
Publication type:
Article
Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
Published in:
2011
By:
- Anderson, Carl A.;
- Boucher, Gabrielle;
- Lees, Charlie W.;
- Franke, Andre;
- D'Amato, Mauro;
- Taylor, Kent D.;
- Lee, James C.;
- Goyette, Philippe;
- Imielinski, Marcin;
- Latiano, Anna;
- Lagacé, Caroline;
- Scott, Regan;
- Amininejad, Leila;
- Bumpstead, Suzannah;
- Baidoo, Leonard;
- Baldassano, Robert N.;
- Barclay, Murray;
- Bayless, Theodore M;
- Brand, Stephan;
- Büning, Carsten
Publication type:
Correction Notice
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
Published in:
Nature Genetics, 2011, v. 43, n. 3, p. 246, doi. 10.1038/ng.764
By:
- Anderson, Carl A.;
- Boucher, Gabrielle;
- Lees, Charlie W.;
- Franke, Andre;
- D'Amato, Mauro;
- Taylor, Kent D.;
- Lee, James C.;
- Goyette, Philippe;
- Imielinski, Marcin;
- Latiano, Anna;
- Lagacé, Caroline;
- Scott, Regan;
- Amininejad, Leila;
- Bumpstead, Suzannah;
- Baidoo, Leonard;
- Baldassano, Robert N.;
- Barclay, Murray;
- Bayless, Theodore M.;
- Brand, Stephan;
- Büning, Carsten
Publication type:
Article
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
Published in:
Nature Genetics, 2010, v. 42, n. 12, p. 1118, doi. 10.1038/ng.717
By:
- Franke, Andre;
- McGovern, Dermot P. B.;
- Barrett, Jeffrey C.;
- Kai Wang;
- Radford-Smith, Graham L.;
- Ahmad, Tariq;
- Lees, Charlie W.;
- Balschun, Tobias;
- Lee, James;
- Roberts, Rebecca;
- Anderson, Carl A.;
- Bis, Joshua C.;
- Bumpstead, Suzanne;
- Ellinghaus, David;
- Festen, Eleonora M.;
- Georges, Michel;
- Green, Todd;
- Haritunians, Talin;
- Jostins, Luke;
- Latiano, Anna
Publication type:
Article
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
Published in:
Nature Genetics, 2008, v. 40, n. 6, p. 710, doi. 10.1038/ng.145
By:
- Fisher, Sheila A.;
- Tremelling, Mark;
- Anderson, Carl A;
- Gwilliam, Rhian;
- Bumpstead, Suzannah;
- Prescott, Natalie J.;
- Nimmo, Elaine R.;
- Massey, Dunecan;
- Berzuini, Carlo;
- Johnson, Christopher;
- Barrett, Jeffrey C.;
- Cummings, Fraser R.;
- Drummond, Hazel;
- Lees, Charlie W.;
- Onnie, Clive M.;
- Hanson, Catherine E.;
- Blaszczyk, Katarzyna;
- Inouye, Mike;
- Ewels, Philip;
- Ravindrarajah, Radhi
Publication type:
Article
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
Published in:
Nature Genetics, 2007, v. 39, n. 7, p. 830, doi. 10.1038/ng2061
By:
- Parkes, Miles;
- Barrett, Jeffrey C.;
- Prescott, Natalie J.;
- Tremelling, Mark;
- Anderson, Carl A.;
- Fisher, Sheila A.;
- Roberts, Roland G.;
- Nimmo, Elaine R.;
- Cummings, Fraser R.;
- Soars, Dianne;
- Drummond, Hazel;
- Lees, Charlie W.;
- Khawaja, Saud A.;
- Bagnall, Richard;
- Burke, Denis A.;
- Todhunter, Catherine E.;
- Ahmad, Tariq;
- Onnie, Clive M.;
- McArdle, Wendy;
- Strachan, David
Publication type:
Article
The Impact of Different DNA Extraction Kits and Laboratories upon the Assessment of Human Gut Microbiota Composition by 16S rRNA Gene Sequencing.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088982
By:
- Kennedy, Nicholas A.;
- Walker, Alan W.;
- Berry, Susan H.;
- Duncan, Sylvia H.;
- Farquarson, Freda M.;
- Louis, Petra;
- Thomson, John M.;
- Satsangi, Jack;
- Flint, Harry J.;
- Parkhill, Julian;
- Lees, Charlie W.;
- Hold, Georgina L.
Publication type:
Article
Analysis of colectomy rates for ulcerative colitis in pre‐ and postbiological eras in Lothian, Scotland.
Published in:
Colorectal Disease, 2021, v. 23, n. 5, p. 1175, doi. 10.1111/codi.15491
By:
- Jenkinson, Philip W.;
- Plevris, Nikolas;
- Lyons, Mathew;
- Grant, Rebecca;
- Fulforth, James;
- Kirkwood, Kate;
- Arnott, Ian D.;
- Wilson, David;
- Watson, Angus J. M.;
- Jones, Gareth‐Rhys;
- Lees, Charlie W.
Publication type:
Article
Implementation of CT-P13 via a Managed Switch Programme in Crohn's Disease: 12-Month Real-World Outcomes.
Published in:
2019
By:
- Plevris, Nikolas;
- Jones, Gareth R.;
- Jenkinson, Philip W.;
- Lyons, Mathew;
- Chuah, Cher S.;
- Merchant, Lynne M.;
- Pattenden, Rebecca J.;
- Watson, Eleanor F.;
- Ho, Gwo-Tzer;
- Noble, Colin L.;
- Din, Shahida;
- Shand, Alan G.;
- Arnott, Ian D.;
- Lees, Charlie W.
Publication type:
journal article
Paediatric Patients (Less Than Age of 17 Years) Account for Less Than 1.5% of All Prevalent Inflammatory Bowel Disease Cases.
Published in:
2020
By:
- Burgess, Christopher J.;
- Henderson, Paul;
- Jones, Gareth-Rhys;
- Lees, Charlie W.;
- Wilson, David C.;
- Lothian IBD registry group
Publication type:
journal article
Long-term outcomes and predictors of vedolizumab persistence in ulcerative colitis.
Published in:
Therapeutic Advances in Gastroenterology, 2024, p. 1, doi. 10.1177/17562848241258372
By:
- Gros, Beatriz;
- Ross, Hannah;
- Nwabueze, Maureen;
- Constantine-Cooke, Nathan;
- Derikx, Lauranne A. A. P.;
- Lyons, Mathew;
- O'Hare, Claire;
- Noble, Colin;
- Arnott, Ian D.;
- Jones, Gareth-Rhys;
- Lees, Charlie W.;
- Plevris, Nikolas
Publication type:
Article
Validation of the ACE [Albumin, CRP, and Endoscopy] Index in Acute Colitis: Analysis of the CONSTRUCT dataset.
Published in:
Journal of Crohn's & Colitis, 2024, v. 18, n. 2, p. 286, doi. 10.1093/ecco-jcc/jjad148
By:
- Grant, Rebecca K;
- Jones, Gareth-Rhys;
- Plevris, Nikolas;
- Lynch, Ruairi W;
- Brindle, William M;
- Hutchings, Hayley A;
- Williams, John G;
- Alrubaiy, Laith;
- Watkins, Alan;
- Lees, Charlie W;
- Arnott, Ian D R
Publication type:
Article
Defining Comprehensive Disease Control for Use as a Treatment Target for Ulcerative Colitis in Clinical Practice: International Delphi Consensus Recommendations.
Published in:
Journal of Crohn's & Colitis, 2024, v. 18, n. 1, p. 91, doi. 10.1093/ecco-jcc/jjad130
By:
- Schreiber, Stefan;
- Danese, Silvio;
- Dignass, Axel;
- Domènech, Eugeni;
- Fantini, Massimo C;
- Ferrante, Marc;
- Halfvarson, Jonas;
- Hart, Ailsa;
- Magro, Fernando;
- Lees, Charlie W;
- Leone, Salvo;
- Pierik, Marieke J;
- Peters, Michele;
- Field, Polly;
- Fishpool, Helen;
- Peyrin-Biroulet, Laurent
Publication type:
Article
Adalimumab and Infliximab Impair SARS-CoV-2 Antibody Responses: Results from a Therapeutic Drug Monitoring Study in 11 422 Biologic-Treated Patients.
Published in:
Journal of Crohn's & Colitis, 2022, v. 16, n. 3, p. 389, doi. 10.1093/ecco-jcc/jjab153
By:
- Chanchlani, Neil;
- Lin, Simeng;
- Chee, Desmond;
- Hamilton, Benjamin;
- Nice, Rachel;
- Arkir, Zehra;
- Bewshea, Claire;
- Cipriano, Bessie;
- Derikx, Lauranne A A P;
- Dunlop, Allan;
- Greathead, Louise;
- Griffiths, Rachel L;
- Ibraheim, Hajir;
- Kelleher, Peter;
- Kok, Klaartje B;
- Lees, Charlie W;
- MacDonald, Jonathan;
- Sebastian, Shaji;
- Smith, Philip J;
- McDonald, Timothy J
Publication type:
Article
Effectiveness and Safety of Adalimumab Biosimilar SB5 in Inflammatory Bowel Disease: Outcomes in Originator to SB5 Switch, Double Biosimilar Switch and Bio-Naïve SB5 Observational Cohorts.
Published in:
Journal of Crohn's & Colitis, 2021, v. 15, n. 12, p. 2011, doi. 10.1093/ecco-jcc/jjab100
By:
- Derikx, Lauranne A A P;
- Dolby, Heather W;
- Plevris, Nikolas;
- Lucaciu, Laura;
- Rees, Caitlin S;
- Lyons, Mathew;
- Siakavellas, Spyros I;
- Constantine-Cooke, Nathan;
- Jenkinson, Philip;
- Su, Shanna;
- O'Hare, Claire;
- Kirckpatrick, Laura;
- Merchant, Lynne M;
- Noble, Colin;
- Arnott, Ian D;
- Jones, Gareth-Rhys;
- Lees, Charlie W
Publication type:
Article
The Impact of NOD2 Genetic Variants on the Gut Mycobiota in Crohn's Disease Patients in Remission and in Individuals Without Gastrointestinal Inflammation.
Published in:
Journal of Crohn's & Colitis, 2021, v. 15, n. 5, p. 800, doi. 10.1093/ecco-jcc/jjaa220
By:
- Nelson, Andrew;
- Stewart, Christopher J;
- Kennedy, Nicholas A;
- Lodge, John K;
- Tremelling, Mark;
- Probert, Chris S;
- Parkes, Miles;
- Mansfield, John C;
- Smith, Darren L;
- Hold, Georgina L;
- Lees, Charlie W;
- Bridge, Simon H;
- Lamb, Christopher A;
- Consortium, UK IBD Genetics
Publication type:
Article
Clinical Utility And Diagnostic Accuracy of Faecal Calprotectin For IBD At First Presentation To Gastroenterology Services In Adults Aged 16-50 Years.
Published in:
Journal of Crohn's & Colitis, 2015, v. 9, n. 1, p. 41, doi. 10.1016/j.crohns.2014.07.005
By:
- Kennedy, Nicholas A.;
- Clark, Annalie;
- Walkden, Andrew;
- Chang, Jeff C. W.;
- Fascí-Spurio, Federica;
- Muscat, Martina;
- Gordon, Brydon W.;
- Kingstone, Kathleen;
- Satsangi, Jack;
- Arnott, Ian D. R.;
- Lees, Charlie W.
Publication type:
Article
Modeling of Treatment Outcomes with Tofacitinib Maintenance Therapy in Patients with Ulcerative Colitis: A Post Hoc Analysis of Data from the OCTAVE Clinical Program.
Published in:
Advances in Therapy, 2023, v. 40, n. 10, p. 4440, doi. 10.1007/s12325-023-02603-0
By:
- Chiorean, Michael;
- Daperno, Marco;
- Lees, Charlie W.;
- Bonfanti, Gianluca;
- Soudis, Dimitrios;
- Modesto, Irene;
- Deuring, J. Jasper;
- Edwards, Roger A.
Publication type:
Article
Analysis of Germline GLI1 Variation Implicates Hedgehog Signalling in the Regulation of Intestinal Inflammatory Pathways.
Published in:
PLoS Medicine, 2008, v. 5, n. 12, p. e239, doi. 10.1371/journal.pmed.0050239
By:
- Lees, Charlie W.;
- Zicharias, William J.;
- Tremelling, Mark;
- Noble, Colin L.;
- Nimmo, Elaine R;
- Tenesa, Albert;
- Cornelius, Jennine;
- Torkvist, Leif;
- Kao, John;
- Farrington, Susan;
- Drummond, Hazel E.;
- Gwo-Tzer Ho;
- Arnott, Ian D. R;
- Appelman, Henry D.;
- Diehl, Lauri;
- Campbell, Harry;
- Dunlop, Malcolm G.;
- Parkes, Miles;
- Howie, Sarah E. M.;
- Gumucio, Deborah L.
Publication type:
Article
Prediction of early clinical response in patients receiving tofacitinib in the OCTAVE Induction 1 and 2 studies.
Published in:
Therapeutic Advances in Gastroenterology, 2021, v. 14, p. 1, doi. 10.1177/17562848211054710
By:
- Lees, Charlie W.;
- Deuring, J. Jasper;
- Chiorean, Michael;
- Daperno, Marco;
- Bonfanti, Gianluca;
- Germino, Rebecca;
- Brown, Pritha Bhadra;
- Modesto, Irene;
- Edwards, Roger A.
Publication type:
Article
Prediction of early clinical response in patients receiving tofacitinib in the OCTAVE Induction 1 and 2 studies.
Published in:
Therapeutic Advances in Gastroenterology, 2021, v. 14, p. 1, doi. 10.1177/17562848211054710
By:
- Lees, Charlie W.;
- Deuring, J. Jasper;
- Chiorean, Michael;
- Daperno, Marco;
- Bonfanti, Gianluca;
- Germino, Rebecca;
- Brown, Pritha Bhadra;
- Modesto, Irene;
- Edwards, Roger A.
Publication type:
Article

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