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Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.
Published in:
Nature Medicine, 2006, v. 12, n. 10, p. 1160, doi. 10.1038/nm1475
By:
- Leen, Ann M.;
- Myers, G. Doug;
- Sili, Uluhan;
- Huls, M. Helen;
- Weiss, Heidi;
- Leung, Kathryn S.;
- Carrum, George;
- Krance, Robert A.;
- Chang, Chung-Che;
- Molldrem, Jeffrey J.;
- Gee, Adrian P.;
- Brenner, Malcolm K.;
- Heslop, Helen E.;
- Rooney, Cliona M.;
- Bollard, Catherine M.
Publication type:
Article
T cell immune profiling of respiratory syncytial virus for the development of a targeted immunotherapy.
Published in:
British Journal of Haematology, 2023, v. 202, n. 4, p. 874, doi. 10.1111/bjh.18933
By:
- Papayanni, Penelope Georgia;
- Koukoulias, Kiriakos;
- Kuvalekar, Manik;
- Watanabe, Ayumi;
- Velazquez, Yovana;
- Ramos, Carlos A.;
- Leen, Ann M.;
- Vasileiou, Spyridoula
Publication type:
Article
Graft Versus Leukemia Response Without Graft-versus-host Disease Elicited By Adoptively Transferred Multivirus-specific T-cells.
Published in:
Molecular Therapy, 2015, v. 23, n. 1, p. 179, doi. 10.1038/mt.2014.192
By:
- Melenhorst, Jan J;
- Castillo, Paul;
- Hanley, Patrick J;
- Keller, Michael D;
- Krance, Robert A;
- Margolin, Judith;
- Leen, Ann M;
- Heslop, Helen E;
- Barrett, A John;
- Rooney, Cliona M;
- Bollard, Catherine M
Publication type:
Article
Reversal of Tumor Immune Inhibition Using a Chimeric Cytokine Receptor.
Published in:
Molecular Therapy, 2014, v. 22, n. 6, p. 1211, doi. 10.1038/mt.2014.47
By:
- Leen, Ann M;
- Sukumaran, Sujita;
- Watanabe, Norihiro;
- Mohammed, Somala;
- Keirnan, Jacqueline;
- Yanagisawa, Ryu;
- Anurathapan, Usanarat;
- Rendon, David;
- Heslop, Helen E;
- Rooney, Cliona M;
- Brenner, Malcolm K;
- Vera, Juan F
Publication type:
Article
Systemic Inflammatory Response Syndrome After Administration of Unmodified T Lymphocytes.
Published in:
Molecular Therapy, 2014, v. 22, n. 6, p. 1134, doi. 10.1038/mt.2014.48
By:
- Papadopoulou, Anastasia;
- Krance, Robert A;
- Allen, Carl E;
- Lee, Daniel;
- Rooney, Cliona M;
- Brenner, Malcolm K;
- Leen, Ann M;
- Heslop, Helen E
Publication type:
Article
Kinetics of Tumor Destruction by Chimeric Antigen Receptor-modified T Cells.
Published in:
Molecular Therapy, 2014, v. 22, n. 3, p. 623, doi. 10.1038/mt.2013.262
By:
- Anurathapan, Usanarat;
- Chan, Robert C;
- Hindi, Hakeem F;
- Mucharla, Roopa;
- Bajgain, Pradip;
- Hayes, Brendan C;
- Fisher, William E;
- Heslop, Helen E;
- Rooney, Cliona M;
- Brenner, Malcolm K;
- Leen, Ann M;
- Vera, Juan F
Publication type:
Article
Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant.
Published in:
Molecular Therapy, 2013, v. 21, n. 11, p. 2113, doi. 10.1038/mt.2013.151
By:
- Gerdemann, Ulrike;
- Katari, Usha L;
- Papadopoulou, Anastasia;
- Keirnan, Jacqueline M;
- Craddock, John A;
- Liu, Hao;
- Martinez, Caridad A;
- Kennedy-Nasser, Alana;
- Leung, Kathryn S;
- Gottschalk, Stephen M;
- Krance, Robert A;
- Brenner, Malcolm K;
- Rooney, Cliona M;
- Heslop, Helen E;
- Leen, Ann M
Publication type:
Article
Rapidly Generated Multivirus-specific Cytotoxic T Lymphocytes for the Prophylaxis and Treatment of Viral Infections.
Published in:
Molecular Therapy, 2012, v. 20, n. 8, p. 1622, doi. 10.1038/mt.2012.130
By:
- Gerdemann, Ulrike;
- Keirnan, Jacqueline M;
- Katari, Usha L;
- Yanagisawa, Ryu;
- Christin, Anne S;
- Huye, Leslie E;
- Perna, Serena K;
- Ennamuri, Sravya;
- Gottschalk, Stephen;
- Brenner, Malcolm K;
- Heslop, Helen E;
- Rooney, Cliona M;
- Leen, Ann M
Publication type:
Article
Antiviral T-cell therapy.
Published in:
Immunological Reviews, 2014, v. 258, n. 1, p. 12, doi. 10.1111/imr.12138
By:
- Leen, Ann M.;
- Heslop, Helen E.;
- Brenner, Malcolm K.
Publication type:
Article
T lymphocytes targeting native receptors.
Published in:
Immunological Reviews, 2014, v. 257, n. 1, p. 39, doi. 10.1111/imr.12133
By:
- Rooney, Cliona M.;
- Leen, Ann M.;
- Vera, Juan F.;
- Heslop, Helen E.
Publication type:
Article
Activity of Broad-Spectrum T Cells as Treatment for AdV, EBV, CMV, BKV, and HHV6 Infections after HSCT.
Published in:
Science Translational Medicine, 2014, v. 6, n. 242, p. 1, doi. 10.1126/scitranslmed.3008825
By:
- Papadopoulou, Anastasia;
- Gerdemann, Ulrike;
- Katari, Usha L.;
- Tzannou, Ifigenia;
- Hao Liu;
- Martinez, Caridad;
- Leung, Kathryn;
- Carrum, George;
- Gee, Adrian P.;
- Vera, Juan F.;
- Krance, Robert A.;
- Brenner, Malcolm K.;
- Rooney, Cliona M.;
- Heslop, Helen E.;
- Leen, Ann M.
Publication type:
Article
Cytotoxic T Lymphocytes Simultaneously Targeting Multiple Tumor-associated Antigens to Treat EBV Negative Lymphoma.
Published in:
Molecular Therapy, 2011, v. 19, n. 12, p. 2258, doi. 10.1038/mt.2011.167
By:
- Gerdemann, Ulrike;
- Katari, Usha;
- Christin, Anne S;
- Cruz, Conrad R;
- Tripic, Tamara;
- Rousseau, Alexandra;
- Gottschalk, Stephen M;
- Savoldo, Barbara;
- Vera, Juan F;
- Heslop, Helen E;
- Brenner, Malcolm K;
- Bollard, Catherine M;
- Rooney, Cliona M;
- Leen, Ann M
Publication type:
Article
PiggyBac-mediated Cancer Immunotherapy Using EBV-specific Cytotoxic T-cells Expressing HER2-specific Chimeric Antigen Receptor.
Published in:
Molecular Therapy, 2011, v. 19, n. 12, p. 2133, doi. 10.1038/mt.2011.131
By:
- Nakazawa, Yozo;
- Huye, Leslie E;
- Salsman, Vita S;
- Leen, Ann M;
- Ahmed, Nabil;
- Rollins, Lisa;
- Dotti, Gianpietro;
- Gottschalk, Stephen M;
- Wilson, Matthew H;
- Rooney, Cliona M
Publication type:
Article
Nucleofection of DCs to Generate Multivirus-specific T Cells for Prevention or Treatment of Viral Infections in the Immunocompromised Host.
Published in:
Molecular Therapy, 2009, v. 17, n. 9, p. 1616, doi. 10.1038/mt.2009.140
By:
- Gerdemann, Ulrike;
- Christin, Anne S.;
- Vera, Juan F.;
- Ramos, Carlos A.;
- Fujita, Yuriko;
- Hao Liu;
- Dilloo, Dagmar;
- Heslop, Helen E.;
- Brenner, Malcolm K.;
- Rooney, Cliona M.;
- Leen, Ann M.
Publication type:
Article
Genetic Manipulation of Tumor-specific Cytotoxic T Lymphocytes to Restore Responsiveness to IL-7.
Published in:
Molecular Therapy, 2009, v. 17, n. 5, p. 880, doi. 10.1038/mt.2009.34
By:
- Vera, Juan F.;
- Hoyos, Valentina;
- Savoldo, Barbara;
- Quintarelli, Concetta;
- Attianese, Greta M. P. Giordano;
- Leen, Ann M.;
- Hao Liu;
- Foster, Aaron E.;
- Heslop, Helen E.;
- Rooney, Cliona M.;
- Brenner, Malcolm K.;
- Dotti, Gianpietro
Publication type:
Article
266. Gene Modification of T Antigen Presenting Cells for the Induction of Antitumor Immunity.
Published in:
Molecular Therapy, 2006, v. 13, p. S101, doi. 10.1016/j.ymthe.2006.08.320
By:
- Foster, Aaron E.;
- Leen, Ann M.;
- Lee, Timothy;
- Vera, Juan;
- Dotti, Gianpietro;
- Rooney, Cliona M.
Publication type:
Article
800. Adenoviral Transduced Monocytes: Efficient Antigen Presenting Cells for the Activation of Antigen-Specific T Cells
Published in:
2005
By:
- Leen, Ann M.;
- Ratnayake, Maheshika K.;
- Foster, Aaron E.;
- Rooney, Cliona M.;
- Gottschalk, Stephen
Publication type:
Abstract
Cytotoxic T lymphocytes as immune-therapy in haematological practice.
Published in:
British Journal of Haematology, 2008, v. 143, n. 2, p. 169, doi. 10.1111/j.1365-2141.2008.07316.x
By:
- Leen, Ann M.;
- Heslop, Helen E.
Publication type:
Article
Adenovirus as an emerging pathogen in immunocompromised patients.
Published in:
British Journal of Haematology, 2005, v. 128, n. 2, p. 135, doi. 10.1111/j.1365-2141.2004.05218.x
By:
- Leen, Ann M.;
- Rooney, Cliona M.
Publication type:
Article
Immunologic Profiling of Human Metapneumovirus for the Development of Targeted Immunotherapy.
Published in:
2017
By:
- Tzannou, Ifigeneia;
- Nicholas, Sarah K.;
- Lulla, Premal;
- Aguayo-Hiraldo, Paibel I.;
- Misra, Anisha;
- Martinez, Caridad A.;
- Machado, Annette A.;
- Orange, Jordan S.;
- Piedra, Pedro A.;
- Vera, Juan F.;
- Leen, Ann M.
Publication type:
journal article
Characterizing the Cellular Immune Response to Parainfluenza Virus 3.
Published in:
2017
By:
- Aguayo-Hiraldo, Paibel I.;
- Arasaratnam, Reuben J.;
- Tzannou, Ifigeneia;
- Kuvalekar, Manik;
- Lulla, Premal;
- Naik, Swati;
- Martinez, Caridad A.;
- Piedra, Pedro A.;
- Vera, Juan F.;
- Leen, Ann M.
Publication type:
journal article

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