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Kinetic modeling of the plasma pharmacokinetic profiles of ADAMTS13 fragment and its Fc-fusion counterpart in mice.
- Published in:
- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1352842
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- Article
H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-40635-1
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- Article
Runx3 inhibits endothelial progenitor cell differentiation and function via suppression of HIF-1α activity.
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- International Journal of Oncology, 2019, v. 54, n. 4, p. 1327
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- Article
Quinic Acid‐Conjugated Nanoparticles Enhance Drug Delivery to Solid Tumors via Interactions with Endothelial Selectins.
- Published in:
- Small, 2018, v. 14, n. 50, p. 1, doi. 10.1002/smll.201803601
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- Publication type:
- Article
A Comparative In Vivo Study of Albumin‐Coated Paclitaxel Nanocrystals and Abraxane.
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- Small, 2018, v. 14, n. 16, p. 1, doi. 10.1002/smll.201703670
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- Publication type:
- Article
Population pharmacokinetics of PEGylated liposomal CPT-11 (IHL-305) in patients with advanced solid tumors.
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- European Journal of Clinical Pharmacology, 2013, v. 69, n. 12, p. 2073, doi. 10.1007/s00228-013-1580-y
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- Article
Gender differences in the hepatic elimination and pharmacokinetics of lobeglitazone in rats.
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- Biopharmaceutics & Drug Disposition, 2015, v. 36, n. 6, p. 410, doi. 10.1002/bdd.1954
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- Article
Thymidylate Synthase Genotype-Directed Chemotherapy for Patients with Gastric and Gastroesophageal Junction Cancers.
- Published in:
- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107424
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- Article
<i>PSMB9</i> Codon 60 Polymorphisms Have No Impact on the Activity of the Immunoproteasome Catalytic Subunit B1i Expressed in Multiple Types of Solid Cancer.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073732
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- Article
Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors [Corrigendum].
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- International Journal of Nanomedicine, 2019, v. 14, p. 5751, doi. 10.2147/IJN.S207276
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- Article
Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors.
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- International Journal of Nanomedicine, 2015, v. 10, p. 1201, doi. 10.2147/IJN.S62911
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- Publication type:
- Article
Determination of chemically reduced pyrrolobenzodiazepine SJG-136 in human plasma by HPLC-MS/MS: application to an anticancer phase I dose escalation study.
- Published in:
- Journal of Mass Spectrometry, 2008, v. 43, n. 1, p. 42, doi. 10.1002/jms.1268
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- Article
Cell-to-Medium Concentration Ratio Overshoot in the Uptake of Statins by Human Hepatocytes in Suspension, but Not in Monolayer: Kinetic Analysis Suggesting a Partial Loss of Functional OATP1Bs.
- Published in:
- AAPS Journal, 2020, v. 22, n. 6, p. N.PAG, doi. 10.1208/s12248-020-00512-6
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- Article
Alternative Splicing: Expanding Diversity in Major ABC and SLC Drug Transporters.
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- AAPS Journal, 2017, v. 19, n. 6, p. 1643, doi. 10.1208/s12248-017-0150-0
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- Article
Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy.
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- AAPS Journal, 2015, v. 17, n. 3, p. 535, doi. 10.1208/s12248-015-9740-x
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- Publication type:
- Article
Polymer micelle formulation for the proteasome inhibitor drug carfilzomib: Anticancer efficacy and pharmacokinetic studies in mice.
- Published in:
- PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0173247
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- Publication type:
- Article
High-Resolution Snapshots of Proteasome Inhibitors in Action Revise Inhibition Paradigms and Inspire Next-Generation Inhibitor Design.
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- ChemBioChem, 2016, v. 17, n. 22, p. 2115, doi. 10.1002/cbic.201600488
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- Article
Elucidating the Catalytic Subunit Composition of Distinct Proteasome Subtypes: A Crosslinking Approach Employing Bifunctional Activity-Based Probes.
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- ChemBioChem, 2015, v. 16, n. 2, p. 284, doi. 10.1002/cbic.201402491
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- Publication type:
- Article
Activity-Based Near-Infrared Fluorescent Probe for LMP7: A Chemical Proteomics Tool for the Immunoproteasome in Living Cells.
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- ChemBioChem, 2012, v. 13, n. 13, p. 1899, doi. 10.1002/cbic.201200307
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- Article
Cover Picture: Activity-Based Near-Infrared Fluorescent Probe for LMP7: A Chemical Proteomics Tool for the Immunoproteasome in Living Cells (ChemBioChem 13/2012).
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- ChemBioChem, 2012, v. 13, n. 13, p. 1829, doi. 10.1002/cbic.201290053
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- Publication type:
- Article
The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
- Published in:
- Nature Medicine, 2003, v. 9, n. 2, p. 220, doi. 10.1038/nm815
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- Article
A phase I study of pegylated liposomal doxorubicin and temsirolimus in patients with refractory solid malignancies.
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- 2014
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- Publication type:
- Report
Phase I and pharmacokinetic study of IHL-305 (PEGylated liposomal irinotecan) in patients with advanced solid tumors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2012, v. 70, n. 5, p. 699, doi. 10.1007/s00280-012-1960-5
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- Publication type:
- Article
A phase I trial of SJG-136 (NSC#694501) in advanced solid tumors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 5, p. 833, doi. 10.1007/s00280-009-1088-4
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- Publication type:
- Article
Expanded Physiologically‐Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction.
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- CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 11, p. 845, doi. 10.1002/psp4.12457
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- Article
Physiologically-Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter-Mediated Interactions Between Metformin and Cimetidine.
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- CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 6, p. 396, doi. 10.1002/psp4.12398
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- Article
Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype-Guided Dosing of Tamoxifen.
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- CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 7, p. 474, doi. 10.1002/psp4.12307
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- Article
Comprehensive PBPK Model of Rifampicin for Quantitative Prediction of Complex Drug‐Drug Interactions: CYP3A/2C9 Induction and OATP Inhibition Effects.
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- CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 3, p. 186, doi. 10.1002/psp4.12275
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- Article