Works by Lee, Sam W

Results: 41

p53-mediated heterochromatin reorganization regulates its cell fate decisions.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 5, p. 478, doi. 10.1038/nsmb.2271

By:

Mungamuri, Sathish Kumar;
Benson, Erica Kay;
Wang, Shaomeng;
Gu, Wei;
Lee, Sam W;
Aaronson, Stuart A

Publication type:

Article

Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Published in:

2015

By:

Raj, Lakshmi;
Ide, Takao;
Gurkar, Aditi U.;
Foley, Michael;
Schenone, Monica;
Li, Xiaoyu;
Tolliday, Nicola J.;
Golub, Todd R.;
Carr, Steven A.;
Shamji, Alykhan F.;
Stern, Andrew M.;
Mandinova, Anna;
Schreiber, Stuart L.;
Lee, Sam W.

Publication type:

Correction Notice

VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01186-7

By:

Borggrewe, Malte;
Kooistra, Susanne M.;
Wesseling, Evelyn M.;
Gierschek, Fenja L.;
Brummer, Maaike L.;
Nowak, Elizabeth C.;
Medeiros-Furquim, Tiago;
Otto, Tegan A.;
Lee, Sam W.;
Noelle, Randolph J.;
Eggen, Bart J. L.;
Laman, Jon D.

Publication type:

Article

DNAJB9, a novel target gene of p53, binds to p53 and inhibits the transcriptional activity.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A661, doi. 10.1096/fasebj.21.5.a661

By:

Jee In Heo;
Mi-Suk Lee;
Eun-Mi Choi;
Yu-Jin Jeong;
Jun-Kyung Kim;
Lee, Sam W.;
Han, Jeong A.;
Jong-Il Kim

Publication type:

Article

Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response.

Published in:

FASEB Journal, 2006, v. 20, n. 13, p. 2375, doi. 10.1096/fj.06-5957fje

By:

Junghee Lee;
Kosaras, Bela;
Aleyasin, Hossein;
Han, Jeong A.;
Park, David S.;
Ratan, Rajiv R.;
Kowall, Neil W.;
Ferrante, Robert J.;
Lee, Sam W.;
Hoon Ryu

Publication type:

Article

Identification of ROCK1 as an Upstream Activator of the JIP-3 to JNK Signaling Axis in Response to UVB Damage.

Published in:

Science Signaling, 2008, v. 1, n. 47, p. 1, doi. 10.1126/scisignal.1161938

By:

Ongusaha, Pat P.;
Qi, Hank H.;
Raj, Lakshmi;
Kim, Young-Bum;
Aaronson, Stuart A.;
Davis, Roger J.;
Yang Shi;
Liao, James K.;
Lee, Sam W.

Publication type:

Article

Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1225081

By:

Noelle, Randolph J.;
Lines, J. Louise;
Lewis, Lionel D.;
Martell, Robert E.;
Guillaudeux, Thierry;
Lee, Sam W.;
Mahoney, Kathleen M.;
Vesely, Matthew D.;
Boyd-Kirkup, Jerome;
Nambiar, Dhanya K.;
Scott, Andrew M.

Publication type:

Article

Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells.

Published in:

Oncogene, 1997, v. 14, n. 17, p. 2025, doi. 10.1038/sj.onc.1201033

By:

Watanabe, Yoshifumi;
Lee, Sam W;
Detmar, Michael;
Ajioka, Itsuki;
Dvorak, Harold F

Publication type:

Article

Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

Published in:

Nature Neuroscience, 2012, v. 15, n. 10, p. 1391, doi. 10.1038/nn.3207

By:

Huang, Hu;
Kong, Dong;
Byun, Kyung Hee;
Ye, Chianping;
Koda, Shuichi;
Lee, Dae Ho;
Oh, Byung-Chul;
Lee, Sam W;
Lee, Bonghee;
Zabolotny, Janice M;
Kim, Min Seon;
Bjørbæk, Christian;
Lowell, Bradford B;
Kim, Young-Bum

Publication type:

Article

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04092-0

By:

Kwon, Eunjeong;
Todorova, Kristina;
Wang, Jun;
Horos, Rastislav;
Lee, Kevin K.;
Neel, Victor A.;
Negri, Gian Luca;
Sorensen, Poul H.;
Lee, Sam W.;
Hentze, Matthias W.;
Mandinova, Anna

Publication type:

Article

Caveolin-1 controls BRCA1 gene expression and cellular localization in human breast cancer cells

Published in:

FEBS Letters, 2006, v. 580, n. 22, p. 5268, doi. 10.1016/j.febslet.2006.08.071

By:

Glait, Chen;
Ravid, Dana;
Lee, Sam W.;
Liscovitch, Mordechai;
Werner, Haim

Publication type:

Article

Cellular senescence and organismal ageing in the absence of p21CIP1/WAF1 in ku80?/? mice.

Published in:

EMBO Reports, 2011, v. 12, n. 3, p. 283, doi. 10.1038/embor.2011.30

By:

Zhao, Bo;
Benson, Erica K;
Qiao, Ruifang;
Wang, Xing;
Kim, Sunchin;
Manfredi, James J;
Lee, Sam W;
Aaronson, Stuart A

Publication type:

Article

Cellular senescence and organismal ageing in the absence of p21CIP1/WAF1 in ku80−/− mice.

Published in:

EMBO Reports, 2009, v. 10, n. 1, p. 71, doi. 10.1038/embor.2008.220

By:

Zhao, Bo;
Benson, Erica K;
Qiao, Ruifang;
Wang, Xing;
Kim, Sunchin;
Manfredi, James J;
Lee, Sam W;
Aaronson, Stuart A

Publication type:

Article

BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest.

Published in:

Oncogene, 2003, v. 22, n. 24, p. 3749, doi. 10.1038/sj.onc.1206439

By:

Ongusaha, Pat P;
Ouchi, Toru;
Kim, Kyung-tae;
Nytko, Emily;
Kwak, Jennifer C;
Duda, Rosemary B;
Deng, Chu-Xia;
Lee, Sam W

Publication type:

Article

Modulation of p53 and p73 levels by cyclin G: implication of a negative feedback regulation.

Published in:

Oncogene, 2003, v. 22, n. 11, p. 1678, doi. 10.1038/sj.onc.1206306

By:

Ohtsuka, Takao;
Ryu, Hoon;
Minamishima, Yohji A;
Ryo, Akihide;
Lee, Sam W

Publication type:

Article

p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53.

Published in:

Oncogene, 1999, v. 18, n. 18, p. 2789, doi. 10.1038/sj.onc.1202615

By:

Fang, Li;
Igarashi, Makoto;
Leung, Jennifer;
Sugrue, Mary M;
Lee, Sam W;
Aaronson, Stuart A

Publication type:

Article

Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells.

Published in:

Oncogene, 1998, v. 16, n. 11, p. 1391, doi. 10.1038/sj.onc.1201661

By:

Lee, Sam W;
Reimer, Corinne L;
Oh, Phil;
Campbell, Doreen B;
Schnitzer, Jan E

Publication type:

Article

p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop.

Published in:

EMBO Journal, 2003, v. 22, n. 6, p. 1289, doi. 10.1093/emboj/cdg129

By:

Ongusaha, Pat P.;
Kim, Jong-il;
Li Fang;
Wong, Tai W.;
Vancopoulos, George D.;
Aaronson, Stuart A.;
Lee, Sam W.

Publication type:

Article

p53-mediated induction of Cox-2 counteracts p53- or genotoxic stress-induced apoptosis.

Published in:

EMBO Journal, 2002, v. 21, n. 21, p. 5635, doi. 10.1093/emboj/cdf591

By:

Han, Jeong A.;
Jong-Il Kim;
Ongusaha, Pat P.;
Hwang, Daniel H.;
Ballou, Leslie R.;
Mahale, Alka;
Aaronson, Stuart A.;
Lee, Sam W.

Publication type:

Article

Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence.

Published in:

EMBO Journal, 2002, v. 21, n. 9, p. 2180, doi. 10.1093/emboj/21.9.2180

By:

Macip, Salvador;
Igarashi, Makoto;
Li Fang;
Angus Chen;
Zhen-Qiang Pan;
Lee, Sam W.;
Aaronson, Stuart A.

Publication type:

Article

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

Published in:

EMBO Journal, 2001, v. 20, n. 13, p. 3459, doi. 10.1093/emboj/20.13.3459

By:

Wulf, Gerburg M.;
Ryo, Akihide;
Wulf, Gerald G.;
Lee, Sam W.;
Niu, Tianhua;
Petkova, Victoria;
Kun Ping Lu

Publication type:

Article

p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades.

Published in:

EMBO Journal, 2001, v. 20, n. 8, p. 1931, doi. 10.1093/emboj/20.8.1931

By:

Li Fang;
Guangnan Li;
Guizhong Liu;
Lee, Sam W.;
Aaronson, Stuart A.

Publication type:

Article

Influence of Induced Reactive Oxygen Species in p53-Mediated Cell Fate Decisions.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 23, p. 8576, doi. 10.1128/MCB.23.23.8576-8585.2003

By:

Macip, Salvador;
Igarashi, Makoto;
Berggren, Petra;
Jian Yu;
Lee, Sam W.;
Aaronson, Stuart A.

Publication type:

Article

X-Linked Inhibitor of Apoptosis Protein as a Therapeutic Target in Metastatic Melanoma.

Published in:

Journal of Investigative Dermatology, 2010, v. 130, n. 9, p. 2169, doi. 10.1038/jid.2010.205

By:

Fang Tian;
Lee, Sam W.

Publication type:

Article

The negative role of cyclin G in ATM-dependent p53 activation.

Published in:

Oncogene, 2004, v. 23, n. 31, p. 5405, doi. 10.1038/sj.onc.1207693

By:

Ohtsuka, Takao;
Jensen, Michael R.;
Kim, Hyung Gu;
Kim, Kyung-tae;
Lee, Sam W.

Publication type:

Article

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway.

Published in:

Oncogene, 2003, v. 22, n. 55, p. 8931, doi. 10.1038/sj.onc.1207057

By:

Aglipay, Jason A;
Lee, Sam W;
Okada, Shinya;
Fujiuchi, Nobuko;
Ohtsuka, Takao;
Kwak, Jennifer C;
Yi Wang;
Johnstone, Ricky W;
Chuxia Deng;
Qin, Jun;
Ouchi, Toru

Publication type:

Article

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.

Published in:

Nature Communications, 2013, v. 4, n. 7, p. 2189, doi. 10.1038/ncomms3189

By:

Gurkar, Aditi U.;
Chu, Kiki;
Raj, Lakshmi;
Bouley, Richard;
Lee, Seung-Hwan;
Kim, Young-Bum;
Dunn, Sandra E.;
Mandinova, Anna;
Lee, Sam W.

Publication type:

Article

Maximizing tumor cell invasion.

Published in:

Pigment Cell & Melanoma Research, 2009, v. 22, n. 2, p. 148, doi. 10.1111/j.1755-148X.2009.00542.x

By:

Ongusaha, Pat P.;
Lee, Sam W.

Publication type:

Article

A small molecule that binds Hedgehog and blocks its signaling in human cells.

Published in:

Nature Chemical Biology, 2009, v. 5, n. 3, p. 154, doi. 10.1038/nchembio.142

By:

Stanton, Benjamin Z;
Peng, Lee F.;
Maloof, Nicole;
Nakai, Kazuo;
Wang, Xiang;
Duffner, Jay L.;
Taveras, Kennedy M;
Hyman, Joel M;
Lee, Sam W.;
Koehler, Angela N.;
Chen, James K.;
Fox, Julia L.;
Mandinova, Anna;
Schreiber, Stuart L.

Publication type:

Article

Prolyl 4-hydroxylation regulates Argonaute 2 stability.

Published in:

Nature, 2008, v. 455, n. 7211, p. 421, doi. 10.1038/nature07186

By:

Qi, Hank H.;
Ongusaha, Pat P.;
Myllyharju, Johanna;
Dongmei Cheng;
Pakkanen, Outi;
Yujiang Shi;
Lee, Sam W.;
Junmin Peng;
Yang Shi

Publication type:

Article

GAMT joins the p53 network.

Published in:

Cell Cycle, 2010, v. 9, n. 9, p. 1706, doi. 10.4161/cc.9.9.11473

By:

Ide, Takao;
Kiki Chu;
Aaronson, Stuart A.;
Lee, Sam W.

Publication type:

Article

Effects of p21 deletion in mouse models of premature aging.

Published in:

Cell Cycle, 2009, v. 8, n. 13, p. 2002, doi. 10.4161/cc.8.13.8997

By:

Benson, Erica K.;
Bo Zhao;
Sassoon, David A.;
Lee, Sam W.;
Aaronson, Stuart A.

Publication type:

Article

p53 promoter selection.

Published in:

Cell Cycle, 2008, v. 7, n. 2, p. 154, doi. 10.4161/cc.7.2.5236

By:

Das, Sanjeev;
Boswell, Sarah A.;
Aaronson, Stuart A.;
Lee, Sam W.

Publication type:

Article

A putative role for Discoidin Domain Receptor 1 in cancer chemoresistance.

Published in:

Cell Adhesion & Migration, 2018, v. 12, n. 4, p. 394, doi. 10.1080/19336918.2018.1445954

By:

Ambrogio, Chiara;
Darbo, Elodie;
Lee, Sam W.;
Santamaría, David

Publication type:

Article

Sulforaphene suppresses growth of colon cancer-derived tumors via induction of glutathione depletion and microtubule depolymerization.

Published in:

Molecular Nutrition & Food Research, 2016, v. 60, n. 5, p. 1068, doi. 10.1002/mnfr.201501011

By:

Byun, Sanguine;
Shin, Seung Ho;
Park, Jiman;
Lim, Semi;
Lee, Eunjung;
Lee, Chaeyoon;
Sung, Dongeun;
Farrand, Lee;
Lee, Seoung Rak;
Kim, Ki Hyun;
Dong, Zigang;
Lee, Sam W.;
Lee, Ki Won

Publication type:

Article

The p53 Pathway as a Target in Cancer Therapeutics: Obstacles and Promise.

Published in:

Science Translational Medicine, 2011, v. 3, n. 64, p. 1, doi. 10.1126/scitranslmed.3001366

By:

Mandinova, Anna;
Lee, Sam W.

Publication type:

Article

Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Published in:

2012

By:

Raj, Lakshmi;
Ide, Takao;
Gurkar, Aditi U.;
Foley, Michael;
Schenone, Monica;
Li, Xiaoyu;
Tolliday, Nicola J.;
Golub, Todd R.;
Carr, Steven A.;
Shamji, Alykhan F.;
Stern, Andrew M.;
Mandinova, Anna;
Schreiber, Stuart L.;
Lee, Sam W.

Publication type:

Correction Notice

Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Published in:

Nature, 2011, v. 475, n. 7355, p. 231, doi. 10.1038/nature10167

By:

Raj, Lakshmi;
Ide, Takao;
Gurkar, Aditi U.;
Foley, Michael;
Schenone, Monica;
Xiaoyu Li;
Tolliday, Nicola J.;
Golub, Todd R.;
Carr, Steven A.;
Shamji, Alykhan F.;
Stern, Andrew M.;
Mandinova, Anna;
Schreiber, Stuart L.;
Lee, Sam W.

Publication type:

Article

ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway.

Published in:

Nature Cell Biology, 2004, v. 6, n. 2, p. 121, doi. 10.1038/ncb1087

By:

Macip, Salvador;
Sagara, Junji;
Hoon Ryu;
Minamishima, Yohji A.;
Nakayama, Keiichi I.;
Aaronson, Stuart A.;
Ohtsuka, Takao;
Lee, Sam W.

Publication type:

Article

CDIP, a novel pro-apoptotic gene, regulates TNFα-mediated apoptosis in a p53-dependent manner.

Published in:

EMBO Journal, 2007, v. 26, n. 14, p. 3410, doi. 10.1038/sj.emboj.7601779

By:

Brown, Lauren;
Ongusaha, Pat P.;
Hyung-Gu Kim;
Shanthy Nuti;
Mandinova, Anna;
Ji Won Lee;
Roya Khosravi-Far;
Aaronson, Stuart A.;
Lee, Sam W.

Publication type:

Article

Expression of Concern for Lee et al., "Overexpression of Kinase-Associated Phosphatase (KAP) in Breast and Prostate Cancer and Inhibition of the Transformed Phenotype by Antisense KAP Expression".

Published in:

Molecular & Cellular Biology, 2019, v. 39, n. 9, p. 1, doi. 10.1128/MCB.00088-19

By:

Lee, Sam W.;
Reimer, Corinne L.;
Li Fang;
Iruela-Arispe, M. Luisa;
Aaronson, Stuart A.

Publication type:

Article