Works by Lee, Der-Yen

Results: 22

Synthesis and Characterization of the Ethylene-Carbonate-Linked L-Valine Derivatives of 4,4-Dimethylcurcumin with Potential Anticancer Activities.

Published in:

Molecules, 2021, v. 26, n. 22, p. 7050, doi. 10.3390/molecules26227050

By:

Lee, Der-Yen;
Lin, Hui-Yi;
Ramasamy, Manickavasakam;
Kuo, Sheng-Chu;
Lee, Pei-Chih;
Hsieh, Min-Tsang

Publication type:

Article

Synthesis, Anticancer Activity, and Preliminary Pharmacokinetic Evaluation of 4,4-Disubstituted Curcuminoid 2,2-bis(Hydroxymethyl)Propionate Derivatives.

Published in:

Molecules, 2020, v. 25, n. 3, p. 479, doi. 10.3390/molecules25030479

By:

Lee, Der-Yen;
Hou, Yu-Chi;
Yang, Jai-Sing;
Lin, Hui-Yi;
Chang, Tsu-Yuan;
Lee, Kuo-Hsiung;
Kuo, Sheng-Chu;
Hsieh, Min-Tsang;
Kuo, Ping-Chung

Publication type:

Article

A systematic identification of anti-inflammatory active components derived from Mu Dan Pi and their applications in inflammatory bowel disease.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-74201-x

By:

Chen, Tzu-Fan;
Hsu, Jeh-Ting;
Wu, Kun-Chang;
Hsiao, Che-Fang;
Lin, Jou-An;
Cheng, Yun-Hsin;
Liu, Yu-Huei;
Lee, Der-Yen;
Chang, Hen-Hong;
Cho, Der-Yang;
Hsu, Jye-Lin

Publication type:

Article

Electroacupuncture at Zusanli and at Neiguan characterized point specificity in the brain by metabolomic analysis.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67766-0

By:

Lee, Der-Yen;
Jiu, Yu-Rung;
Hsieh, Ching-Liang

Publication type:

Article

A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli.

Published in:

Cell Death & Disease, 2018, v. 9, n. 3, p. 1, doi. 10.1038/s41419-018-0423-2

By:

Kuo, Cheng-Ju;
Wang, Sin-Tian;
Lin, Chia-Mei;
Chiu, Hao-Chieh;
Huang, Cheng-Rung;
Lee, Der-Yen;
Chang, Geen-Dong;
Chou, Ting-Chen;
Chen, Jenn-Wei;
Chen, Chang-Shi

Publication type:

Article

Glutamine Metabolism in Both the Oxidative and Reductive Directions Is Triggered in Shrimp Immune Cells (Hemocytes) at the WSSV Genome Replication Stage to Benefit Virus Replication.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02102

By:

He, Shu-Ting;
Lee, Der-Yen;
Tung, Cheng-Yi;
Li, Chun-Yuan;
Wang, Han-Ching

Publication type:

Article

4,4‐Diallyl curcumin bis(2,2‐hydroxymethyl)propanoate ameliorates nonalcoholic steatohepatitis in methionine‐choline‐deficient diet and Western diet mouse models.

Published in:

Chemical Biology & Drug Design, 2024, v. 103, n. 5, p. 1, doi. 10.1111/cbdd.14532

By:

Yang, Li‐Chan;
Wang, Chih‐Chiang;
Lee, Der‐Yen;
Lin, Wen‐Chuan;
Kuo, Sheng‐Chu;
Juang, Shin‐Hun;
Hsieh, Min‐Tsang

Publication type:

Article

Docosahexaenoic Acid Inhibits Cell Proliferation through a Suppression of c-Myc Protein in Pancreatic Ductal Adenocarcinoma Cells.

Published in:

Antioxidants, 2021, v. 10, n. 11, p. 1721, doi. 10.3390/antiox10111721

By:

Syu, Jia-Ning;
Lee, Der-Yen;
Hung, Hung-Chang;
Li, Chia-Ying;
Lin, Hung-Yu;
Chiang, En-Pei Isabel;
Chen, Yi-Heng;
Huang, Shu-Ming;
Tang, Feng-Yao

Publication type:

Article

Docosahexaenoic Acid Alleviates Trimethylamine- N -oxide-mediated Impairment of Neovascularization in Human Endothelial Progenitor Cells.

Published in:

Nutrients, 2023, v. 15, n. 9, p. 2190, doi. 10.3390/nu15092190

By:

Syu, Jia-Ning;
Lin, Hung-Yu;
Huang, Tun Yu;
Lee, Der-Yen;
Chiang, En-Pei Isabel;
Tang, Feng-Yao

Publication type:

Article

Evaluations and Mechanistic Interrogation of Natural Products Isolated From Paeonia suffruticosa for the Treatment of Inflammatory Bowel Disease.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.696158

By:

Wu, Kun-Chang;
Lee, Der-Yen;
Hsu, Jeh-Ting;
Cheng, Chi-Fang;
Lan, Joung-Liang;
Chiu, Shao-Chih;
Cho, Der-Yang;
Hsu, Jye-Lin

Publication type:

Article

METTL4-mediated nuclear N6-deoxyadenosine methylation promotes metastasis through activating multiple metastasis-inducing targets.

Published in:

Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-022-02819-3

By:

Hsu, Kai-Wen;
Lai, Joseph Chieh-Yu;
Chang, Jeng-Shou;
Peng, Pei-Hua;
Huang, Ching-Hui;
Lee, Der-Yen;
Tsai, Yu-Cheng;
Chung, Chi-Jung;
Chang, Han;
Chang, Chao-Hsiang;
Chen, Ji-Lin;
Pang, See-Tong;
Hao, Ziyang;
Cui, Xiao-Long;
He, Chuan;
Wu, Kou-Juey

Publication type:

Article

Acupuncture modulates development of myopia by reducing NLRP3 inflammasome activation via the dopamine-D1R signaling pathway.

Published in:

Acupuncture in Medicine, 2023, v. 41, n. 6, p. 364, doi. 10.1177/09645284231170886

By:

Chen, Chih-Sheng;
Lin, Chi-Fong;
Chou, Yung-Lan;
Lee, Der-Yen;
Tien, Peng-Tai;
Wang, Yao-Chien;
Chang, Ching-Yao;
Lin, En-Shyh;
Chen, Jamie Jiin;
Wu, Ming-Yen;
Ku, Hsiangyu;
Gan, Dekang;
Chang, Yung-Ming;
Lin, Hui-Ju;
Wan, Lei

Publication type:

Article

Metabolism modulation in rat tissues in response to point specificity of electroacupuncture.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04382-6

By:

Lee, Der-Yen;
Jiu, Yu-Rung;
Hsieh, Ching-Liang

Publication type:

Article

The Effects of a Curcumin Derivative and Osimertinib on Fatty Acyl Metabolism and Mitochondrial Functions in HCC827 Cells and Tumors.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 15, p. 12190, doi. 10.3390/ijms241512190

By:

Hsieh, Min-Tsang;
Lee, Pei-Chih;
Chiang, Yi-Ting;
Lin, Hui-Yi;
Lee, Der-Yen

Publication type:

Article

H 2 S- and Redox-State-Mediated PTP1B S-Sulfhydration in Insulin Signaling.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2898, doi. 10.3390/ijms24032898

By:

Lin, Yu-Chin;
Zeng, Wan-Ting;
Lee, Der-Yen

Publication type:

Article

Biochemical Regulation of the Glyoxalase System in Response to Insulin Signaling.

Published in:

Antioxidants, 2021, v. 10, n. 2, p. 326, doi. 10.3390/antiox10020326

By:

Lee, Der-Yen;
Lin, Yu-Chin;
Chang, Geen-Dong;
Antognelli, Cinzia

Publication type:

Article

Dual-specificity phosphatase 23 mediates GCM1 dephosphorylation and activation.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 3, p. 848, doi. 10.1093/nar/gkq838

By:

Lin, Fang-Yu;
Chang, Ching-Wen;
Cheong, Mei-Leng;
Chen, Hsei-Chorn;
Lee, Der-Yen;
Chang, Geen-Dong;
Chen, Hungwen

Publication type:

Article

An Invertebrate Warburg Effect: A Shrimp Virus Achieves Successful Replication by Altering the Host Metabolome via the PI3K-Akt-mTOR Pathway.

Published in:

PLoS Pathogens, 2014, v. 10, n. 6, p. 1, doi. 10.1371/journal.ppat.1004196

By:

Su, Mei-An;
Huang, Yun-Tzu;
Chen, I-Tung;
Lee, Der-Yen;
Hsieh, Yun-Chieh;
Li, Chun-Yuan;
Ng, Tze Hann;
Liang, Suh-Yuen;
Lin, Shu-Yu;
Huang, Shiao-Wei;
Chiang, Yi-An;
Yu, Hon-Tsen;
Khoo, Kay-Hooi;
Chang, Geen-Dong;
Lo, Chu-Fang;
Wang, Han-Ching

Publication type:

Article

Six Hours after Infection, the Metabolic Changes Induced by WSSV Neutralize the Host's Oxidative Stress Defenses.

Published in:

Scientific Reports, 2016, p. 27732, doi. 10.1038/srep27732

By:

Chen, I-Tung;
Lee, Der-Yen;
Huang, Yun-Tzu;
Kou, Guang-Hsiung;
Wang, Han-Ching;
Chang, Geen-Dong;
Lo, Chu-Fang

Publication type:

Article

Glucose- and glutamine-driven de novo nucleotide synthesis facilitates WSSV replication in shrimp.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02186-z

By:

Chen, Cong-Yan;
Chen, Chih-Ling;
Ng, Yen Siong;
Lee, Der-Yen;
Lin, Shih-Shun;
Huang, Chien-Kang;
Kumar, Ramya;
Wang, Han-Ching

Publication type:

Article

Docosahexaenoic acid inhibits the proliferation of Kras/TP53 double mutant pancreatic ductal adenocarcinoma cells through modulation of glutathione level and suppression of nucleotide synthesis.

Published in:

PLoS ONE, 2020, v. 15, n. 11, p. 1, doi. 10.1371/journal.pone.0241186

By:

Hung, Wei-Chia;
Lee, Der-Yen;
Chiang, En-Pei Isabel;
Syu, Jia-Ning;
Chao, Che-Yi;
Yang, Mei-Due;
Tsai, Shu-Yao;
Tang, Feng-Yao

Publication type:

Article

Recent advances in LC‐MS‐based metabolomics for clinical biomarker discovery.

Published in:

Mass Spectrometry Reviews, 2023, v. 42, n. 6, p. 2349, doi. 10.1002/mas.21785

By:

Chen, Chao‐Jung;
Lee, Der‐Yen;
Yu, Jiaxin;
Lin, Yu‐Ning;
Lin, Tsung‐Min

Publication type:

Article