Works by Leapman, Richard D.

Results: 31

Protein Oxidation Implicated as the Primary Determinant of Bacterial Radioresistance.

Published in:

PLoS Biology, 2007, v. 5, n. 4, p. 0769, doi. 10.1371/journal.pbio.0050092

By:

Daly, Michael J.;
Gaidamakova, Elena K.;
Matrosova, Vera Y.;
Vasilenko, Alexander;
Min Zhai;
Leapman, Richard D.;
Lai, Barry;
Ravel, Bruce;
Li, Shu-Mei W.;
Kemner, Kenneth M.;
Fredrickson, James K.

Publication type:

Article

Contributions of David Joy to Electron Microscopy at the NIH (ca. 1980–2020).

Published in:

2023

By:

Leapman, Richard D

Publication type:

Abstract

Comparison of Ultrastructure Determined by Serial Block Face SEM and Focused Ion Beam SEM from Blood Platelets and Thrombi.

Published in:

2022

By:

Leapman, Richard D.;
Cruz, Denzel R.;
Palumbo, Douglas J.;
Akkem, Rahul R.;
Rhee, Sung W.;
Pokrovskaya, Irina D.;
Storrie, Brian;
Aronova, Maria A.

Publication type:

Abstract

Palmitoylation of A-kinase anchoring protein 79/150 modulates its nanoscale organization, trafficking, and mobility in postsynaptic spines.

Published in:

Frontiers in Synaptic Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnsyn.2022.1004154

By:

Xiaobing Chen;
Crosby, Kevin C.;
Feng, Austin;
Purkey, Alicia M.;
Aronova, Maria A.;
Winters, Christine A.;
Crocker, Virginia T.;
Leapman, Richard D.;
Reese, Thomas S.;
Dell'Acqua, Mark L.

Publication type:

Article

Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets.

Published in:

Platelets, 2023, v. 34, n. 1, p. 1, doi. 10.1080/09537104.2023.2264978

By:

Matharu, Sagar S.;
Nordmann, Cassidy S.;
Ottman, Kurtis R.;
Akkem, Rahul;
Palumbo, Douglas;
Cruz, Denzel R. D.;
Campbell, Kenneth;
Sievert, Gail;
Sturgill, Jamie;
Porterfield, James Z.;
Joshi, Smita;
Alfar, Hammodah R.;
Chi Peng;
Pokrovskaya, Irina D.;
Kamykowski, Jeffrey A.;
Wood, Jeremy P.;
Garvy, Beth;
Aronova, Maria A.;
Whiteheart, Sidney W.;
Leapman, Richard D.

Publication type:

Article

Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets.

Published in:

Platelets, 2023, v. 34, n. 1, p. 1, doi. 10.1080/09537104.2023.2264978

By:

Matharu, Sagar S.;
Nordmann, Cassidy S.;
Ottman, Kurtis R.;
Akkem, Rahul;
Palumbo, Douglas;
Cruz, Denzel R. D.;
Campbell, Kenneth;
Sievert, Gail;
Sturgill, Jamie;
Porterfield, James Z.;
Joshi, Smita;
Alfar, Hammodah R.;
Peng, Chi;
Pokrovskaya, Irina D.;
Kamykowski, Jeffrey A.;
Wood, Jeremy P.;
Garvy, Beth;
Aronova, Maria A.;
Whiteheart, Sidney W.;
Leapman, Richard D.

Publication type:

Article

Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape.

Published in:

Platelets, 2021, v. 32, n. 5, p. 608, doi. 10.1080/09537104.2020.1799970

By:

Pokrovskaya, Irina;
Tobin, Michael;
Desai, Rohan;
Aronova, Maria A.;
Kamykowski, Jeffrey A.;
Zhang, Guofeng;
Joshi, Smita;
Whiteheart, Sidney W.;
Leapman, Richard D.;
Storrie, Brian

Publication type:

Article

Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis.

Published in:

Platelets, 2021, v. 32, n. 1, p. 97, doi. 10.1080/09537104.2020.1719993

By:

Pokrovskaya, Irina D.;
Tobin, Michael;
Desai, Rohan;
Joshi, Smita;
Kamykowski, Jeffrey A.;
Zhang, Guofeng;
Aronova, Maria A.;
Whiteheart, Sidney W.;
Leapman, Richard D.;
Storrie, Brian

Publication type:

Article

Golgi proteins in circulating human platelets are distributed across non-stacked, scattered structures.

Published in:

Platelets, 2017, v. 28, n. 4, p. 400, doi. 10.1080/09537104.2016.1235685

By:

Yadav, Shilpi;
Williamson, Jonathan K.;
Aronova, Maria A.;
Prince, Andrew A.;
Pokrovskaya, Irina D.;
Leapman, Richard D.;
Storrie, Brian

Publication type:

Article

Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02615-y

By:

Rhee, Sung W.;
Pokrovskaya, Irina D.;
Ball, Kelly K.;
Ling, Kenny;
Vedanaparti, Yajnesh;
Cohen, Joshua;
Cruz, Denzel R. D.;
Zhao, Oliver S.;
Aronova, Maria A.;
Zhang, Guofeng;
Kamykowski, Jeffrey A.;
Leapman, Richard D.;
Storrie, Brian

Publication type:

Article

Quantitative STEM mass measurement of biological macromolecules in a 300 kV TEM.

Published in:

Journal of Microscopy, 2007, v. 228, n. 1, p. 25, doi. 10.1111/j.1365-2818.2007.01819.x

By:

SOUSA, ALIOSCKA A.;
LEAPMAN, RICHARD D.

Publication type:

Article

Analysis of directly frozen macromolecules and tissues in the field-emission STEM.

Published in:

Journal of Microscopy, 1991, v. 161, n. 1, p. 3, doi. 10.1111/j.1365-2818.1991.tb03070.x

By:

Leapman, Richard D.;
Andrews, S. Brian

Publication type:

Article

Thickness measurement of hydrated and dehydrated cryosections by EELS.

Published in:

Microscopy Research & Technique, 1996, v. 33, n. 3, p. 241, doi. 10.1002/(SICI)1097-0029(19960215)33:3<241::AID-JEMT1>3.0.CO;2-T

By:

Shi, Shanling;
Sun, Songquan;
Brian Andrews, S.;
Leapman, Richard D.

Publication type:

Article

Cells containing aragonite crystals mediate responses to gravity in Trichoplax adhaerens (Placozoa), an animal lacking neurons and synapses.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190905

By:

Mayorova, Tatiana D.;
Smith, Carolyn L.;
Hammar, Katherine;
Winters, Christine A.;
Pivovarova, Natalia B.;
Aronova, Maria A.;
Leapman, Richard D.;
Reese, Thomas S.

Publication type:

Article

Passive Diffusion as a Mechanism Underlying Ribbon Synapse Vesicle Release and Resupply.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 27, p. 8948, doi. 10.1523/JNEUROSCI.1022-14.2014

By:

Graydon, Cole W.;
Jun Zhang;
Oesch, Nicholas W.;
Sousa, Alioscka A.;
Leapman, Richard D.;
Diamond, Jeffrey S.

Publication type:

Article

PSD-95 Is Required to Sustain the Molecular Organization of the Postsynaptic Density.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 17, p. 6329, doi. 10.1523/JNEUROSCI.5968-10.2011

By:

Xiaobing Chen;
Nelson, Christopher D.;
Xiang Li;
Winters, Christine A.;
Azzam, Rita;
Sousa, Alioscka A.;
Leapman, Richard D.;
Gainer, Harold;
Sheng, Morgan;
Reese, Thomas S.

Publication type:

Article

Synthesis, Characterization, and Direct Intracellular Imaging of Ultrasmall and Uniform Glutathione-Coated Gold Nanoparticles.

Published in:

Small, 2012, v. 8, n. 14, p. 2277, doi. 10.1002/smll.201200071

By:

Sousa, Alioscka A.;
Morgan, Jeffrey T.;
Brown, Patrick H.;
Adams, April;
Jayasekara, M. P. Suresh;
Zhang, Guofeng;
Ackerson, Christopher J.;
Kruhlak, Michael J.;
Leapman, Richard D.

Publication type:

Article

Direct visualization of CaMKII at postsynaptic densities by electron microscopy tomography.

Published in:

Journal of Comparative Neurology, 2012, v. 520, n. 18, p. 4218, doi. 10.1002/cne.23151

By:

Fera, Andrea;
Dosemeci, Ayse;
Sousa, Alioscka A.;
Yang, Charlotte;
Leapman, Richard D.;
Reese, Thomas S.

Publication type:

Article

Nanoparticles: Dissected with electrons.

Published in:

Nature Nanotechnology, 2010, v. 5, n. 7, p. 480, doi. 10.1038/nnano.2010.131

By:

Leapman, Richard D.

Publication type:

Article

Dotted Core–Shell Nanoparticles for T<sub>1</sub>‐Weighted MRI of Tumors.

Published in:

Advanced Materials, 2018, v. 30, n. 33, p. 1, doi. 10.1002/adma.201803163

By:

Shen, Zheyu;
Song, Jibin;
Zhou, Zijian;
Yung, Bryant C.;
Aronova, Maria A.;
Li, Yan;
Dai, Yunlu;
Fan, Wenpei;
Liu, Yijing;
Li, Zihou;
Ruan, Huimin;
Leapman, Richard D.;
Lin, Lisen;
Niu, Gang;
Chen, Xiaoyuan;
Wu, Aiguo

Publication type:

Article

β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions.

Published in:

Nature Communications, 2017, v. 8, n. 2, p. 14295, doi. 10.1038/ncomms14295

By:

Zhu, Lu;
Almaça, Joana;
Dadi, Prasanna K.;
Hong, Hao;
Sakamoto, Wataru;
Rossi, Mario;
Lee, Regina J.;
Vierra, Nicholas C.;
Lu, Huiyan;
Cui, Yinghong;
McMillin, Sara M.;
Perry, Nicole A.;
Gurevich, Vsevolod V.;
Lee, Amy;
Kuo, Bryan;
Leapman, Richard D.;
Matschinsky, Franz M.;
Doliba, Nicolai M.;
Urs, Nikhil M.;
Caron, Marc G.

Publication type:

Article

Biodegradable Gold Nanovesicles with an Ultrastrong Plasmonic Coupling Effect for Photoacoustic Imaging and Photothermal Therapy.

Published in:

Angewandte Chemie, 2013, v. 125, n. 52, p. 14208, doi. 10.1002/ange.201308986

By:

Huang, Peng;
Lin, Jing;
Li, Wanwan;
Rong, Pengfei;
Wang, Zhe;
Wang, Shouju;
Wang, Xiaoping;
Sun, Xiaolian;
Aronova, Maria;
Niu, Gang;
Leapman, Richard D.;
Nie, Zhihong;
Chen, Xiaoyuan

Publication type:

Article

Organization of designed nanofibrils assembled from α-helical peptides as determined by electron microscopy.

Published in:

Journal of Peptide Science, 2004, v. 10, n. 5, p. 291, doi. 10.1002/psc.520

By:

Kajava, Andrey V.;
Potekhin, Sergey A.;
Corradin, Giampietro;
Leapman, Richard D.

Publication type:

Article

Nanoscale 3D cellular imaging by axial scanning transmission electron tomography.

Published in:

Nature Methods, 2009, v. 6, n. 10, p. 729, doi. 10.1038/nmeth.1367

By:

Hohmann-Marriott, Martin F.;
Sousa, Alioscka A.;
Azari, Afrouz A.;
Glushakova, Svetlana;
Zhang, Guofeng;
Zimmerberg, Joshua;
Leapman, Richard D.

Publication type:

Article

Dense cellular segmentation for EM using 2D–3D neural network ensembles.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-81590-0

By:

Guay, Matthew D.;
Emam, Zeyad A. S.;
Anderson, Adam B.;
Aronova, Maria A.;
Pokrovskaya, Irina D.;
Storrie, Brian;
Leapman, Richard D.

Publication type:

Article

Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0142554

By:

Chen, Richard J.;
Zhang, Guofeng;
Garfield, Susan H.;
Shi, Yi-Jun;
Chen, Kevin G.;
Robey, Pamela G.;
Leapman, Richard D.

Publication type:

Article

A Structural Framework for a Near-Minimal Form of Life: Mass and Compositional Analysis of the Helical Mollicute <i>Spiroplasma melliferum</i> BC3.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0087921

By:

Trachtenberg, Shlomo;
Schuck, Peter;
Phillips, Terry M.;
Andrews, S. Brian;
Leapman, Richard D.

Publication type:

Article

Influence of Melanosome Dynamics on Melanoma Drug Sensitivity.

Published in:

JNCI: Journal of the National Cancer Institute, 2009, v. 101, n. 18, p. 1259, doi. 10.1093/jnci/djp259

By:

Chen, Kevin G.;
Leapman, Richard D.;
Zhang, Guofeng;
Lai, Barry;
Valencia, Julio C.;
Cardarelli, Carol O.;
Vieira, Wilfred D.;
Hearing, Vincent J.;
Gottesman, Michael M.

Publication type:

Article

Biodegradable Gold Nanovesicles with an Ultrastrong Plasmonic Coupling Effect for Photoacoustic Imaging and Photothermal Therapy.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 52, p. 13958, doi. 10.1002/anie.201308986

By:

Huang, Peng;
Lin, Jing;
Li, Wanwan;
Rong, Pengfei;
Wang, Zhe;
Wang, Shouju;
Wang, Xiaoping;
Sun, Xiaolian;
Aronova, Maria;
Niu, Gang;
Leapman, Richard D.;
Nie, Zhihong;
Chen, Xiaoyuan

Publication type:

Article

PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology.

Published in:

Scientific Reports, 2017, p. 43606, doi. 10.1038/srep43606

By:

Sweeney, Amanda M.;
Fleming, Kelsey E.;
McCauley, John P.;
Rodriguez, Marvin F.;
Martin, Elliot T.;
Sousa, Alioscka A.;
Leapman, Richard D.;
Scimemi, Annalisa

Publication type:

Article

Compressed Sensing Electron Tomography for Determining Biological Structure.

Published in:

Scientific Reports, 2016, p. 27614, doi. 10.1038/srep27614

By:

Guay, Matthew D.;
Czaja, Wojciech;
Aronova, Maria A.;
Leapman, Richard D.

Publication type:

Article