Works by Le Nours, Jérôme

Results: 22

MR1 presents microbial vitamin B metabolites to MAIT cells.

Published in:

Nature, 2012, v. 491, n. 7426, p. 717, doi. 10.1038/nature11605

By:

Kjer-Nielsen, Lars;
Patel, Onisha;
Corbett, Alexandra J.;
Le Nours, Jérôme;
Meehan, Bronwyn;
Liu, Ligong;
Bhati, Mugdha;
Chen, Zhenjun;
Kostenko, Lyudmila;
Reantragoon, Rangsima;
Williamson, Nicholas A.;
Purcell, Anthony W.;
Dudek, Nadine L.;
McConville, Malcolm J.;
O'Hair, Richard A. J.;
Khairallah, George N.;
Godfrey, Dale I.;
Fairlie, David P.;
Rossjohn, Jamie;
McCluskey, James

Publication type:

Article

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12941-9

By:

Almeida, Catarina F.;
Sundararaj, Srinivasan;
Le Nours, Jérôme;
Praveena, T.;
Cao, Benjamin;
Burugupalli, Satvika;
Smith, Dylan G. M.;
Patel, Onisha;
Brigl, Manfred;
Pellicci, Daniel G.;
Williams, Spencer J.;
Uldrich, Adam P.;
Godfrey, Dale I.;
Rossjohn, Jamie

Publication type:

Article

Molecular recognition of microbial lipid-based antigens by T cells.

Published in:

Cellular & Molecular Life Sciences, 2018, v. 75, n. 9, p. 1623, doi. 10.1007/s00018-018-2749-4

By:

Gras, Stephanie;
Van Rhijn, Ildiko;
Shahine, Adam;
Le Nours, Jérôme

Publication type:

Article

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1.

Published in:

Science Immunology, 2020, v. 5, n. 49, p. 1, doi. 10.1126/sciimmunol.abc9492

By:

Howson, Lauren J.;
Awad, Wael;
von Borstel, Anouk;
Lim, Hui Jing;
McWilliam, Hamish E. G.;
Sandoval-Romero, Maria L.;
Majumdar, Shamik;
Hamzeh, Abdul Rezzak;
Andrews, Thomas D.;
McDermott, David H.;
Murphy, Philip M.;
Le Nours, Jérôme;
Mak, Jeffrey Y. W.;
Liu, Ligong;
Fairlie, David P.;
McCluskey, James;
Villadangos, Jose A.;
Cook, Matthew C.;
Turner, Stephen J.;
Davey, Martin S.

Publication type:

Article

Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products.

Published in:

Science Immunology, 2020, v. 5, n. 43, p. 1, doi. 10.1126/sciimmunol.aax5430

By:

Nicolai, Sarah;
Wegrecki, Marcin;
Cheng, Tan-Yun;
Bourgeois, Elvire A.;
Cotton, Rachel N.;
Mayfield, Jacob A.;
Monnot, Gwennaëlle C.;
Le Nours, Jérôme;
Van Rhijn, Ildiko;
Rossjohn, Jamie;
Moody, D. Branch;
de Jong, Annemieke

Publication type:

Article

Mucosal‐associated invariant T cell receptor recognition of small molecules presented by MR1.

Published in:

Immunology & Cell Biology, 2018, v. 96, n. 6, p. 588, doi. 10.1111/imcb.12017

By:

Awad, Wael;
Le Nours, Jérôme;
Kjer‐Nielsen, Lars;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

Conserved allomorphs of MR1 drive the specificity of MR1-restricted TCRs.

Published in:

Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1419528

By:

Cornforth, Terri V.;
Moyo, Nathifa;
Cole, Suzanne;
Lam, Emily P. S.;
Lobry, Tatiana;
Wolchinsky, Ron;
Lloyd, Angharad;
Ward, Katarzyna;
Denham, Eleanor M.;
Masi, Giulia;
Tea Qing Yun, Phyllis;
Moore, Colin;
Dhaouadi, Selsabil;
Besra, Gurdyal S.;
Veerapen, Natacha;
Illing, Patricia T.;
Vivian, Julian P.;
Raynes, Jeremy M.;
Nours, Jérôme Le;
Purcell, Anthony W.

Publication type:

Article

Corrigendum: State of play in the molecular presentation and recognition of anti-tumor lipid-based analogues.

Published in:

2025

By:

Praveena, T.;
Le Nours, Jérôme

Publication type:

Correction Notice

State of play in the molecular presentation and recognition of anti-tumor lipid-based analogues.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1479382

By:

Praveena, T.;
Le Nours, Jérôme

Publication type:

Article

State of play in the molecular presentation and recognition of anti-tumor lipid-based analogues.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1479382

By:

Praveena, T.;
Le Nours, Jérôme

Publication type:

Article

Novel Molecular Insights into Human Lipid-Mediated T Cell Immunity.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2617, doi. 10.3390/ijms22052617

By:

Shahine, Adam;
Wegrecki, Marcin;
Le Nours, Jérôme;
Campese, Antonio

Publication type:

Article

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid.

Published in:

Nature Communications, 2016, v. 7, n. 10, p. 13257, doi. 10.1038/ncomms13257

By:

Gras, Stephanie;
Van Rhijn, Ildiko;
Shahine, Adam;
Cheng, Tan-Yun;
Bhati, Mugdha;
Tan, Li Lynn;
Halim, Hanim;
Tuttle, Kathryn D.;
Gapin, Laurent;
Le Nours, Jérôme;
Moody, D. Branch;
Rossjohn, Jamie

Publication type:

Article

Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.

Published in:

Nature Communications, 2016, v. 7, n. 2, p. 10570, doi. 10.1038/ncomms10570

By:

Le Nours, Jérôme;
Praveena, T.;
Pellicci, Daniel G.;
Gherardin, Nicholas A.;
Ross, Fiona J.;
Lim, Ricky T.;
Besra, Gurdyal S.;
Keshipeddy, Santosh;
Richardson, Stewart K.;
Howell, Amy R.;
Gras, Stephanie;
Godfrey, Dale I.;
Rossjohn, Jamie;
Uldrich, Adam P.

Publication type:

Article

Recognition of vitamin B metabolites by mucosal-associated invariant T cells.

Published in:

Nature Communications, 2013, v. 4, n. 7, p. 2142, doi. 10.1038/ncomms3142

By:

Patel, Onisha;
Kjer-Nielsen, Lars;
Le Nours, Jérôme;
Eckle, Sidonia B. G.;
Birkinshaw, Richard;
Beddoe, Travis;
Corbett, Alexandra J.;
Liu, Ligong;
Miles, John J.;
Meehan, Bronwyn;
Reantragoon, Rangsima;
Sandoval-Romero, Maria L.;
Sullivan, Lucy C.;
Brooks, Andrew G.;
Chen, Zhenjun;
Fairlie, David P.;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

Human skin is colonized by T cells that recognize CD1a independently of lipid.

Published in:

2021

By:

Cotton, Rachel N.;
Tan-Yun Cheng;
Wegrecki, Marcin;
Nours, JérÃ'me Le;
Orgill, Dennis P.;
Pomahac, Bohdan;
Talbot, Simon G.;
Willis, Richard A.;
Altman, John D.;
de Jong, Annemieke;
Ogg, Graham;
Van Rhijn, Ildiko;
Rossjohn, Jamie;
Clark, Rachael A.;
Moody, D. Branch;
Cheng, Tan-Yun;
Le Nours, Jérôme

Publication type:

journal article

Investigating the binding of β-1,4-galactan to Bacillus licheniformis β-1,4-galactanase by crystallography and computational modeling.

Published in:

Proteins, 2009, v. 75, n. 4, p. 977, doi. 10.1002/prot.22310

By:

Le Nours, Jérôme;
De Maria, Leonardo;
Welner, Ditte;
Jørgensen, Christel T.;
Christensen, Lars L. H.;
Borchert, Torben V.;
Larsen, Sine;
Lo Leggio, Leila

Publication type:

Article

Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31443-9

By:

Wegrecki, Marcin;
Ocampo, Tonatiuh A.;
Gunasinghe, Sachith D.;
von Borstel, Anouk;
Tin, Shin Yi;
Reijneveld, Josephine F.;
Cao, Thinh-Phat;
Gully, Benjamin S.;
Le Nours, Jérôme;
Moody, D. Branch;
Van Rhijn, Ildiko;
Rossjohn, Jamie

Publication type:

Article

CD1d-lipid antigen recognition by the γδ TCR.

Published in:

Nature Immunology, 2013, v. 14, n. 11, p. 1137, doi. 10.1038/ni.2713

By:

Uldrich, Adam P;
Le Nours, Jérôme;
Pellicci, Daniel G;
Gherardin, Nicholas A;
McPherson, Kirsty G;
Lim, Ricky T;
Patel, Onisha;
Beddoe, Travis;
Gras, Stephanie;
Rossjohn, Jamie;
Godfrey, Dale I

Publication type:

Article

Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor.

Published in:

Nature Immunology, 2012, v. 13, n. 9, p. 857, doi. 10.1038/ni.2372

By:

Patel, Onisha;
Pellicci, Daniel G;
Gras, Stephanie;
Sandoval-Romero, Maria L;
Uldrich, Adam P;
Mallevaey, Thierry;
Clarke, Andrew J;
Le Nours, Jérôme;
Theodossis, Alex;
Cardell, Susanna L;
Gapin, Laurent;
Godfrey, Dale I;
Rossjohn, Jamie

Publication type:

Article

Recognition of ?-linked self glycolipids mediated by natural killer T cell antigen receptors.

Published in:

Nature Immunology, 2011, v. 12, n. 9, p. 827, doi. 10.1038/ni.2076

By:

Pellicci, Daniel G;
Clarke, Andrew J;
Patel, Onisha;
Mallevaey, Thierry;
Beddoe, Travis;
Le Nours, Jérôme;
Uldrich, Adam P;
McCluskey, James;
Besra, Gurdyal S;
Porcelli, Steven A;
Gapin, Laurent;
Godfrey, Dale I;
Rossjohn, Jamie

Publication type:

Article

Inhibitor binding in a class 2 dihydroorotate dehydrogenase causes variations in the membrane-associated N-terminal domain.

Published in:

Protein Science: A Publication of the Protein Society, 2004, v. 13, n. 4, p. 1031, doi. 10.1110/ps.03533004

By:

Hansen, Majbritt;
Le Nours, Jérôme;
Johansson, Eva;
Antal, Torben;
Ullrich, Alexandra;
Löffler, Monika;
Larsen, Sine

Publication type:

Article

Structure of two fungal β-1,4-galactanases: Searching for the basis for temperature and pH optimum.

Published in:

Protein Science: A Publication of the Protein Society, 2003, v. 12, n. 6, p. 1195, doi. 10.1110/ps.0300103

By:

Le Nours, Jérôme;
Ryttersgaard, Carsten;
Lo Leggio, Leila;
Østergaard, Peter Rahbek;
Borchert, Torben Vedel;
Christensen, Lars Lehmann Hylling;
Larsen, Sine

Publication type:

Article