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An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine-56.
Published in:
Angewandte Chemie, 2017, v. 129, n. 13, p. 3590, doi. 10.1002/ange.201611907
By:
- Pettinger, Jonathan;
- Le Bihan, Yann‐Vaï;
- Widya, Marcella;
- van Montfort, Rob L. M.;
- Jones, Keith;
- Cheeseman, Matthew D.
Publication type:
Article
An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine-56.
Published in:
Angewandte Chemie International Edition, 2017, v. 56, n. 13, p. 3536, doi. 10.1002/anie.201611907
By:
- Pettinger, Jonathan;
- Le Bihan, Yann-Vaï;
- Widya, Marcella;
- Van Montfort, Rob L. M.;
- Jones, Keith;
- Cheeseman, Matthew D.
Publication type:
Article
Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release.
Published in:
Biochemical Journal, 2019, v. 476, n. 18, p. 2521, doi. 10.1042/BCJ20190383
By:
- Felisberto-Rodrigues, Catarina;
- Thomas, Jemima C.;
- McAndrew, Craig;
- Le Bihan, Yann-Vaï;
- Burke, Rosemary;
- Workman, Paul;
- van Montfort, Rob L. M.
Publication type:
Article
Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. N.PAG, doi. 10.1038/s41598-022-23264-z
By:
- Pierrat, Olivier A.;
- Liu, Manjuan;
- Collie, Gavin W.;
- Shetty, Kartika;
- Rodrigues, Matthew J.;
- Le Bihan, Yann-Vaï;
- Gunnell, Emma A.;
- McAndrew, P. Craig;
- Stubbs, Mark;
- Rowlands, Martin G.;
- Yahya, Norhakim;
- Shehu, Erald;
- Talbot, Rachel;
- Pickard, Lisa;
- Bellenie, Benjamin R.;
- Cheung, Kwai-Ming J.;
- Drouin, Ludovic;
- Innocenti, Paolo;
- Woodward, Hannah;
- Davis, Owen A.
Publication type:
Article
A higher-order entity formed by the flexible assembly of RAP1 with TRF2.
Published in:
Nucleic Acids Research, 2016, v. 44, n. 4, p. 1962, doi. 10.1093/nar/gkv1531
By:
- Gaullier, Guillaume;
- Miron, Simona;
- Pisano, Sabrina;
- Buisson, Rámi;
- Le Bihan, Yann-Vaï;
- Tellier-Lebègue, Carine;
- Messaoud, Wala;
- Roblin, Pierre;
- Guimarães, Beatriz G.;
- Thai, Robert;
- Giraud-Panis2, Marie-Josèphe;
- Gilson, Eric;
- ène Le Du, Marie-Hé
Publication type:
Article
The orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNA.
Published in:
Nucleic Acids Research, 2012, v. 40, n. 7, p. 3197, doi. 10.1093/nar/gkr1166
By:
- Matot, Béatrice;
- Le Bihan, Yann-Vaï;
- Lescasse, Rachel;
- Pérez, Javier;
- Miron, Simona;
- David, Gabriel;
- Castaing, Bertrand;
- Weber, Patrick;
- Raynal, Bertrand;
- Zinn-Justin, Sophie;
- Gasparini, Sylvaine;
- Le Du, Marie-Hélène
Publication type:
Article
The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA.
Published in:
Nucleic Acids Research, 2012, v. 40, n. 6, p. 2566, doi. 10.1093/nar/gkr1116
By:
- Poulet, Anaïs;
- Pisano, Sabrina;
- Faivre-Moskalenko, Cendrine;
- Pei, Bei;
- Tauran, Yannick;
- Haftek-Terreau, Zofia;
- Brunet, Frédéric;
- Le Bihan, Yann-Vaï;
- Ledu, Marie-Hélène;
- Montel, Fabien;
- Hugo, Nicolas;
- Amiard, Simon;
- Argoul, Françoise;
- Chaboud, Annie;
- Gilson, Eric;
- Giraud-Panis, Marie-Josèphe
Publication type:
Article
5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases.
Published in:
Nucleic Acids Research, 2011, v. 39, n. 14, p. 6277, doi. 10.1093/nar/gkr215
By:
- Le Bihan, Yann-Vaï;
- Angeles Izquierdo, Maria;
- Coste, Franck;
- Aller, Pierre;
- Culard, Françoise;
- Gehrke, Tim H.;
- Essalhi, Kadija;
- Carell, Thomas;
- Castaing, Bertrand
Publication type:
Article
Front Cover: A Degron Blocking Strategy Towards Improved CRL4<sup>CRBN</sup> Recruiting PROTAC Selectivity (ChemBioChem 23/2023).
Published in:
ChemBioChem, 2023, v. 24, n. 23, p. 1, doi. 10.1002/cbic.202300692
By:
- Bouguenina, Habib;
- Scarpino, Andrea;
- O'Hanlon, Jack A.;
- Warne, Justin;
- Wang, Hannah Z.;
- Wah Hak, Laura Chan;
- Sadok, Amine;
- McAndrew, P. Craig;
- Stubbs, Mark;
- Pierrat, Olivier A.;
- Hahner, Tamas;
- Cabry, Marc P.;
- Le Bihan, Yann‐Vaï;
- Mitsopoulos, Costas;
- Sialana, Fernando J.;
- Roumeliotis, Theodoros I.;
- Burke, Rosemary;
- van Montfort, Rob L. M.;
- Choudhari, Jyoti;
- Chopra, Rajesh
Publication type:
Article
A Degron Blocking Strategy Towards Improved CRL4<sup>CRBN</sup> Recruiting PROTAC Selectivity.
Published in:
ChemBioChem, 2023, v. 24, n. 23, p. 1, doi. 10.1002/cbic.202300351
By:
- Bouguenina, Habib;
- Scarpino, Andrea;
- O'Hanlon, Jack A.;
- Warne, Justin;
- Wang, Hannah Z.;
- Wah Hak, Laura Chan;
- Sadok, Amine;
- McAndrew, P. Craig;
- Stubbs, Mark;
- Pierrat, Olivier A.;
- Hahner, Tamas;
- Cabry, Marc P.;
- Le Bihan, Yann‐Vaï;
- Mitsopoulos, Costas;
- Sialana, Fernando J.;
- Roumeliotis, Theodoros I.;
- Burke, Rosemary;
- van Montfort, Rob L. M.;
- Choudhari, Jyoti;
- Chopra, Rajesh
Publication type:
Article
Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70.
Published in:
Molecules, 2022, v. 27, n. 3, p. 817, doi. 10.3390/molecules27030817
By:
- O'Connor, Suzanne;
- Le Bihan, Yann-Vaï;
- Westwood, Isaac M.;
- Liu, Manjuan;
- Mak, Oi Wei;
- Zazeri, Gabriel;
- Povinelli, Ana P. R.;
- Jones, Alan M.;
- van Montfort, Rob;
- Reynisson, Jóhannes;
- Collins, Ian
Publication type:
Article

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