Works by Lawley, Trevor D.

Results: 35

Interaction between the IncHI1 plasmid R27 coupling protein and type IV secretion system: TraG associates with the coiled-coil mating pair formation protein TrhB.

Published in:

Molecular Microbiology, 2003, v. 49, n. 1, p. 105, doi. 10.1046/j.1365-2958.2003.03551.x

By:

Gilmour, Matthew W.;
Gunton, James E.;
Lawley, Trevor D.;
Taylor, Diane E.

Publication type:

Article

Bacterial conjugative transfer: visualization of successful mating pairs and plasmid establishment in live Escherichia coli.

Published in:

Molecular Microbiology, 2002, v. 44, n. 4, p. 947, doi. 10.1046/j.1365-2958.2002.02938.x

By:

Lawley, Trevor D;
Gordon, G. Scott;
Wright, Andrew;
Taylor, Diane E

Publication type:

Article

Cellular location and temperature-dependent assembly of IncHI1 plasmid R27-encoded TrhC-associated conjugative transfer protein complexes.

Published in:

Molecular Microbiology, 2001, v. 42, n. 3, p. 705, doi. 10.1046/j.1365-2958.2001.02682.x

By:

Gilmour, Matthew W.;
Lawley, Trevor D.;
Rooker, Michelle M.;
Newnham, Peter J.;
Taylor, Diane E.

Publication type:

Article

Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29096-9

By:

Forster, Samuel C.;
Liu, Junyan;
Kumar, Nitin;
Gulliver, Emily L.;
Gould, Jodee A.;
Escobar-Zepeda, Alejandra;
Mkandawire, Tapoka;
Pike, Lindsay J.;
Shao, Yan;
Stares, Mark D.;
Browne, Hilary P.;
Neville, B. Anne;
Lawley, Trevor D.

Publication type:

Article

Global Analysis of the Sporulation Pathway of <i>Clostridium difficile</i>.

Published in:

PLoS Genetics, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pgen.1003660

By:

Fimlaid, Kelly A.;
Bond, Jeffrey P.;
Schutz, Kristin C.;
Putnam, Emily E.;
Leung, Jacqueline M.;
Lawley, Trevor D.;
Shen, Aimee

Publication type:

Article

As Clear as Mud? Determining the Diversity and Prevalence of Prophages in the Draft Genomes of Estuarine Isolates of Clostridium difficile.

Published in:

Genome Biology & Evolution, 2015, v. 7, n. 7, p. 1842, doi. 10.1093/gbe/evv094

By:

Hargreaves, Katherine R.;
Otieno, James R.;
Thanki, Anisha;
Blades, Matthew J.;
Millard, Andrew D.;
Browne, Hilary P.;
Lawley, Trevor D.;
Clokie, Martha R. J.

Publication type:

Article

The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy.

Published in:

2022

By:

Thompson, Nicola A.;
Stewart, Grant D.;
Welsh, Sarah J.;
Doherty, Gary J.;
Robinson, Matthew J.;
Neville, B. Anne;
Vervier, Kevin;
Harris, Simon R.;
Adams, David J.;
Dalchau, Katy;
Bruce, David;
Demiris, Nikolaos;
Lawley, Trevor D.;
Corrie, Pippa G.

Publication type:

journal article

High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach.

Published in:

PLoS Biology, 2019, v. 17, n. 5, p. 1, doi. 10.1371/journal.pbio.3000231

By:

Fung, Connie;
Tan, Shumin;
Nakajima, Mifuyu;
Skoog, Emma C.;
Camarillo-Guerrero, Luis Fernando;
Klein, Jessica A.;
Lawley, Trevor D.;
Solnick, Jay V.;
Fukami, Tadashi;
Amieva, Manuel R.

Publication type:

Article

Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29096-9

By:

Forster, Samuel C.;
Liu, Junyan;
Kumar, Nitin;
Gulliver, Emily L.;
Gould, Jodee A.;
Escobar-Zepeda, Alejandra;
Mkandawire, Tapoka;
Pike, Lindsay J.;
Shao, Yan;
Stares, Mark D.;
Browne, Hilary P.;
Neville, B. Anne;
Lawley, Trevor D.

Publication type:

Article

Comparative genomics identifies potential virulence factors in Clostridium tertium and C. paraputrificum.

Published in:

Virulence, 2019, v. 10, n. 1, p. 657, doi. 10.1080/21505594.2019.1637699

By:

Muñoz, Marina;
Restrepo-Montoya, Daniel;
Kumar, Nitin;
Iraola, Gregorio;
Herrera, Giovanny;
Ríos-Chaparro, Dora I.;
Díaz-Arévalo, Diana;
Patarroyo, Manuel A.;
Lawley, Trevor D.;
Ramírez, Juan David

Publication type:

Article

Evaluation of PacBio sequencing for full-length bacterial 16S rRNA gene classification.

Published in:

BMC Microbiology, 2016, v. 16, p. 1, doi. 10.1186/s12866-016-0891-4

By:

Wagner, Josef;
Coupland, Paul;
Browne, Hilary P.;
Lawley, Trevor D.;
Francis, Suzanna C.;
Julian Parkhill

Publication type:

Article

Gut Microbiome in Human Melioidosis: Composition and Resistome Dynamics from Diagnosis to Discovery.

Published in:

Open Forum Infectious Diseases, 2024, v. 11, n. 11, p. 1, doi. 10.1093/ofid/ofae654

By:

Chowdhury, Soumi;
Kullberg, Robert F J;
Haak, Bastiaan W;
Duran, Claudio;
Earny, Venkat A;
Eshwara, Vandana K;
Lawley, Trevor D;
Wiersinga, W Joost;
Mukhopadhyay, Chiranjay

Publication type:

Article

Should we modulate the neonatal microbiome and what should be the goal?

Published in:

2022

By:

van Best, Niels;
Dominguez-Bello, Maria Gloria;
Hornef, Mathias W.;
Jašarević, Eldin;
Korpela, Katri;
Lawley, Trevor D.

Publication type:

Letter

Integrated genomic epidemiology and phenotypic profiling of Clostridium difficile across intra-hospital and community populations in Colombia.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47688-2

By:

Muñoz, Marina;
Restrepo-Montoya, Daniel;
Kumar, Nitin;
Iraola, Gregorio;
Camargo, Milena;
Díaz-Arévalo, Diana;
Roa-Molina, Nelly S.;
Tellez, Mayra A.;
Herrera, Giovanny;
Ríos-Chaparro, Dora I.;
Birchenall, Claudia;
Pinilla, Darío;
Pardo-Oviedo, Juan M.;
Rodríguez-Leguizamón, Giovanni;
Josa, Diego F.;
Lawley, Trevor D.;
Patarroyo, Manuel A.;
Ramírez, Juan David

Publication type:

Article

The complete DNA sequence and analysis of R27, a large IncHI plasmid from Salmonella typhi that is temperature sensitive for transfer.

Published in:

Nucleic Acids Research, 2000, v. 28, n. 10, p. 2177, doi. 10.1093/nar/28.10.2177

By:

Sherburne, Craig K.;
Lawley, Trevor D.;
Gilmour, Matthew W.;
Blattner, F. R.;
Burland, Valerie;
Grotbeck, Erik;
Rose, Debra J.;
Taylor, Diane E.

Publication type:

Article

Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle.

Published in:

Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02428-6

By:

Browne, Hilary P.;
Almeida, Alexandre;
Kumar, Nitin;
Vervier, Kevin;
Adoum, Anne T.;
Viciani, Elisa;
Dawson, Nicholas J. R.;
Forster, Samuel C.;
Cormie, Claire;
Goulding, David;
Lawley, Trevor D.

Publication type:

Article

The gut microbial metabolic capacity of microbiome-humanized vs. wild type rodents reveals a likely dual role of intestinal bacteria in hepato-intestinal schistosomiasis.

Published in:

PLoS Neglected Tropical Diseases, 2022, v. 16, n. 10, p. 1, doi. 10.1371/journal.pntd.0010878

By:

Cortés, Alba;
Martin, John;
Rosa, Bruce A.;
Stark, Klara A.;
Clare, Simon;
McCarthy, Catherine;
Harcourt, Katherine;
Brandt, Cordelia;
Tolley, Charlotte;
Lawley, Trevor D.;
Mitreva, Makedonka;
Berriman, Matthew;
Rinaldi, Gabriel;
Cantacessi, Cinzia

Publication type:

Article

Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence.

Published in:

Clinical Infectious Diseases, 2016, v. 62, n. 6, p. 746, doi. 10.1093/cid/civ1031

By:

Kumar, Nitin;
Miao He;
Ellison, Louise;
Pickard, Derek;
Dougan, Gordon;
Parkhill, Julian;
Lawley, Trevor D.;
Miyajima, Fabio;
Swale, Andrew;
Pirmohamed, Munir;
Roberts, Paul;
Smith, Godfrey;
Molyneux, Rebecca;
Wren, Brendan W.;
Parry, Christopher M.

Publication type:

Article

Clostridium sordellii genome analysis reveals plasmid localized toxin genes encoded within pathogenicity loci.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12864-015-1613-2

By:

Couchman, Edward C.;
Browne, Hilary P.;
Dunn, Matt;
Lawley, Trevor D.;
Songer, J. Glenn;
Hall, Val;
Petrovska, Liljana;
Vidor, Callum;
Awad, Milena;
Lyras, Dena;
Fairweather, Neil F.

Publication type:

Article

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism.

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-160

By:

Pettit, Laura J.;
Browne, Hilary P.;
Lu Yu;
Smits, Wiep Klaas;
Fagan, Robert P.;
Barquist, Lars;
Martin, Melissa J.;
Goulding, David;
Duncan, Sylvia H.;
Flint, Harry J.;
Dougan, Gordon;
Choudhary, Jyoti S.;
Lawley, Trevor D.

Publication type:

Article

Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice.

Published in:

PLoS Pathogens, 2012, v. 8, n. 10, p. 1, doi. 10.1371/journal.ppat.1002995

By:

Lawley, Trevor D.;
Clare, Simon;
Walker, Alan W.;
Stares, Mark D.;
Connor, Thomas R.;
Raisen, Claire;
Goulding, David;
Rad, Roland;
Schreiber, Fernanda;
Brandt, Cordelia;
Deakin, Laura J.;
Pickard, Derek J.;
Duncan, Sylvia H.;
Flint, Harry J.;
Clark, Taane G.;
Parkhill, Julian;
Dougan, Gordon

Publication type:

Article

Genome-Wide Screen for Salmonella Genes Required for Long-Term Systemic Infection of the Mouse.

Published in:

PLoS Pathogens, 2006, v. 2, n. 2, p. 0087, doi. 10.1371/journal.ppat.0020011

By:

Trevor D., Lawley;
Kaman, Chan;
Lucinda J., Thompson;
Charles C., Kim;
Gregory R., Govoni;
Denise M., Monack

Publication type:

Article

Intestinal colonization resistance.

Published in:

Immunology, 2013, v. 138, n. 1, p. 1, doi. 10.1111/j.1365-2567.2012.03616.x

By:

Lawley, Trevor D.;
Walker, Alan W.

Publication type:

Article

HPMCD: the database of human microbial communities from metagenomic datasets and microbial reference genomes.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 1, p. D604, doi. 10.1093/nar/gkv1216

By:

Forster, Samuel C.;
Browne, Hilary P.;
Kumar, Nitin;
Hunt, Martin;
Denise, Hubert;
Mitchell, Alex;
Finn, Robert D.;
Lawley, Trevor D.

Publication type:

Article

Culturing of female bladder bacteria reveals an interconnected urogenital microbiota.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03968-5

By:

Thomas-White, Krystal;
Forster, Samuel C.;
Kumar, Nitin;
Van Kuiken, Michelle;
Putonti, Catherine;
Stares, Mark D.;
Hilt, Evann E.;
Price, Travis K.;
Wolfe, Alan J.;
Lawley, Trevor D.

Publication type:

Article

Pangenome analysis reveals genetic isolation in Campylobacter hyointestinalis subspecies adapted to different mammalian hosts.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82993-9

By:

Costa, Daniela;
Lévesque, Simon;
Kumar, Nitin;
Fresia, Pablo;
Ferrés, Ignacio;
Lawley, Trevor D.;
Iraola, Gregorio

Publication type:

Article

GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump.

Published in:

Science Signaling, 2019, v. 12, n. 562, p. N.PAG, doi. 10.1126/scisignal.aau9048

By:

Schneditz, Georg;
Elias, Joshua E.;
Pagano, Ester;
Zaeem Cader, M.;
Saveljeva, Svetlana;
Long, Kathleen;
Mukhopadhyay, Subhankar;
Arasteh, Maryam;
Lawley, Trevor D.;
Dougan, Gordon;
Bassett, Andrew;
Karlsen, Tom H.;
Kaser, Arthur;
Kaneider, Nicole C.

Publication type:

Article

Variation in Taxonomic Composition of the Fecal Microbiota in an Inbred Mouse Strain across Individuals and Time.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0142825

By:

Hoy, Yana Emmy;
Bik, Elisabeth M.;
Lawley, Trevor D.;
Holmes, Susan P.;
Monack, Denise M.;
Theriot, Julie A.;
Relman, David A.

Publication type:

Article

Comparative Whole Genome Sequence Analysis of the Carcinogenic Bacterial Model Pathogen Helicobacter felis.

Published in:

Genome Biology & Evolution, 2011, v. 3, p. 302, doi. 10.1093/gbe/evr022

By:

Arnold, Isabelle C.;
Zigova, Zuzana;
Holden, Matthew;
Lawley, Trevor D.;
Rad, Roland;
Dougan, Gordon Dougan;
Falkow, Stanley;
Bentley, Stephen D.;
Müller, Anne

Publication type:

Article

Lipopolysaccharide O structure of adherent and invasive Escherichia coli regulates intestinal inflammation via complement C3.

Published in:

PLoS Pathogens, 2020, v. 16, n. 10, p. 1, doi. 10.1371/journal.ppat.1008928

By:

Ohno, Masashi;
Hasegawa, Mizuho;
Hayashi, Atsushi;
Caballero-Flores, Gustavo;
Alteri, Christopher J.;
Lawley, Trevor D.;
Kamada, Nobuhiko;
Núñez, Gabriel;
Inohara, Naohiro

Publication type:

Article

Enterocloster clostridioformis protects against Salmonella pathogenesis and modulates epithelial and mucosal immune function.

Published in:

Microbiome, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40168-025-02050-9

By:

Beresford-Jones, Benjamin S.;
Suyama, Satoshi;
Clare, Simon;
Soderholm, Amelia;
Xia, Wangmingyu;
Sardar, Puspendu;
Lee, Junhee;
Harcourt, Katherine;
Lawley, Trevor D.;
Pedicord, Virginia A.

Publication type:

Article

A human gut bacterial genome and culture collection for improved metagenomic analyses.

Published in:

Nature Biotechnology, 2019, v. 37, n. 2, p. 186, doi. 10.1038/s41587-018-0009-7

By:

Forster, Samuel C.;
Kumar, Nitin;
Anonye, Blessing O.;
Almeida, Alexandre;
Viciani, Elisa;
Stares, Mark D.;
Dunn, Matthew;
Mkandawire, Tapoka T.;
Zhu, Ana;
Shao, Yan;
Pike, Lindsay J.;
Louie, Thomas;
Browne, Hilary P.;
Mitchell, Alex L.;
Neville, B. Anne;
Finn, Robert D.;
Lawley, Trevor D.

Publication type:

Article

Systematic discovery of probiotics.

Published in:

Nature Biotechnology, 2015, v. 33, n. 1, p. 47, doi. 10.1038/nbt.3111

By:

Forster, Samuel C;
Lawley, Trevor D

Publication type:

Article

Translating the human microbiome.

Published in:

Nature Biotechnology, 2013, v. 31, n. 4, p. 304, doi. 10.1038/nbt.2543

By:

Brown, James;
de Vos, Willem M;
DiStefano, Peter S;
Doré, Joël;
Huttenhower, Curtis;
Knight, Rob;
Lawley, Trevor D;
Raes, Jeroen;
Turnbaugh, Peter

Publication type:

Article

'Know thyself' – host factors influencing cancer response to immune checkpoint inhibitors.

Published in:

Journal of Pathology, 2022, v. 257, n. 4, p. 513, doi. 10.1002/path.5907

By:

Gunjur, Ashray;
Manrique‐Rincón, Andrea J;
Klein, Oliver;
Behren, Andreas;
Lawley, Trevor D;
Welsh, Sarah J;
Adams, David J

Publication type:

Article