Works by Lavrik, Olga I.

Results: 89
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    New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition.

    Published in:
    Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 973, doi. 10.3390/biom11070973
    By:
    • Dyrkheeva, Nadezhda S.;
    • Filimonov, Aleksandr S.;
    • Luzina, Olga A.;
    • Zakharenko, Alexandra L.;
    • Ilina, Ekaterina S.;
    • Malakhova, Anastasia A.;
    • Medvedev, Sergey P.;
    • Reynisson, Jóhannes;
    • Volcho, Konstantin P.;
    • Zakian, Suren M.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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    The Lipophilic Purine Nucleoside—Tdp1 Inhibitor—Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo.

    Published in:
    Molecules, 2023, v. 28, n. 1, p. 323, doi. 10.3390/molecules28010323
    By:
    • Chernyshova, Irina A.;
    • Zakharenko, Aleksandra L.;
    • Kurochkin, Nikolay N.;
    • Dyrkheeva, Nadezhda S.;
    • Kornienko, Tatyana E.;
    • Popova, Nelly A.;
    • Nikolin, Valeriy P.;
    • Ilina, Ekaterina S.;
    • Zharkov, Timofey D.;
    • Kupryushkin, Maxim S.;
    • Oslovsky, Vladimir E.;
    • Drenichev, Mikhail S.;
    • Lavrik, Olga I.
    Publication type:
    Article
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    Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan.

    Published in:
    Molecules, 2022, v. 27, n. 11, p. 3374, doi. 10.3390/molecules27113374
    By:
    • Munkuev, Aldar A.;
    • Dyrkheeva, Nadezhda S.;
    • Kornienko, Tatyana E.;
    • Ilina, Ekaterina S.;
    • Ivankin, Dmitry I.;
    • Suslov, Evgeniy V.;
    • Korchagina, Dina V.;
    • Gatilov, Yuriy V.;
    • Zakharenko, Alexandra L.;
    • Malakhova, Anastasia A.;
    • Reynisson, Jóhannes;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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    In Vitro and In Silico Studies of Human Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) Inhibition by Stereoisomeric Forms of Lipophilic Nucleosides: The Role of Carbohydrate Stereochemistry in Ligand-Enzyme Interactions.

    Published in:
    Molecules, 2022, v. 27, n. 8, p. N.PAG, doi. 10.3390/molecules27082433
    By:
    • Dyrkheeva, Nadezhda S.;
    • Chernyshova, Irina A.;
    • Ivanov, Georgy A.;
    • Porozov, Yuri B.;
    • Zenchenko, Anastasia A.;
    • Oslovsky, Vladimir E.;
    • Zakharenko, Alexandra L.;
    • Nasyrova, Darina I.;
    • Likhatskaya, Galina N.;
    • Mikhailov, Sergey N.;
    • Lavrik, Olga I.;
    • Drenichev, Mikhail S.
    Publication type:
    Article
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    Inhibition of Tyrosyl-DNA Phosphodiesterase 1 by Lipophilic Pyrimidine Nucleosides.

    Published in:
    Molecules, 2020, v. 25, n. 16, p. 3694, doi. 10.3390/molecules25163694
    By:
    • Zakharenko, Alexandra L.;
    • Drenichev, Mikhail S.;
    • Dyrkheeva, Nadezhda S.;
    • Ivanov, Georgy A.;
    • Oslovsky, Vladimir E.;
    • Ilina, Ekaterina S.;
    • Chernyshova, Irina A.;
    • Lavrik, Olga I.;
    • Mikhailov, Sergey N.;
    • Seley-Radtke, Katherine;
    • Agrofoglio, Luigi A.
    Publication type:
    Article
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    Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1.

    Published in:
    Molecules, 2020, v. 25, n. 15, p. 3496, doi. 10.3390/molecules25153496
    By:
    • Il'ina, Irina V.;
    • Dyrkheeva, Nadezhda S.;
    • Zakharenko, Alexandra L.;
    • Sidorenko, Alexander Yu.;
    • Li-Zhulanov, Nikolay S.;
    • Korchagina, Dina V.;
    • Chand, Raina;
    • Ayine-Tora, Daniel M.;
    • Chepanova, Arina A.;
    • Zakharova, Olga D.;
    • Ilina, Ekaterina S.;
    • Reynisson, Jóhannes;
    • Malakhova, Anastasia A.;
    • Medvedev, Sergey P.;
    • Zakian, Suren M.;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.;
    • Sippl, Wolfgang;
    • Sousa, Maria Emília de
    Publication type:
    Article
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    New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors.

    Published in:
    Molecules, 2019, v. 24, n. 20, p. 3711, doi. 10.3390/molecules24203711
    By:
    • Filimonov, Aleksander S.;
    • Chepanova, Arina A.;
    • Luzina, Olga A.;
    • Zakharenko, Alexandra L.;
    • Zakharova, Olga D.;
    • Ilina, Ekaterina S.;
    • Dyrkheeva, Nadezhda S.;
    • Kuprushkin, Maxim S.;
    • Kolotaev, Anton V.;
    • Khachatryan, Derenik S.;
    • Patel, Jinal;
    • Leung, Ivanhoe K.H.;
    • Chand, Raina;
    • Ayine-Tora, Daniel M.;
    • Reynisson, Johannes;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.;
    • Muñoz-Torrero, Diego;
    • Luque, F. Javier
    Publication type:
    Article
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    Sulfide, Sulfoxide, and Sulfone Derivatives of Usnic Acid as Inhibitors of Human TDP1 and TDP2 Enzymes.

    Published in:
    Chemistry (2624-8549), 2024, v. 6, n. 6, p. 1658, doi. 10.3390/chemistry6060101
    By:
    • Filimonov, Aleksandr S.;
    • Mikhailova, Marina A.;
    • Dyrkheeva, Nadezhda S.;
    • Chernyshova, Irina A.;
    • Kornienko, Tatyana E.;
    • Naumenko, Konstantin A.;
    • Anarbaev, Rashid O.;
    • Nefedov, Andrey A.;
    • Achara, Chigozie;
    • Curtis, Anthony D. M.;
    • Luzina, Olga A.;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.;
    • Reynisson, Jóhannes
    Publication type:
    Article
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    The Development of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors. Combination of Monoterpene and Adamantine Moieties via Amide or Thioamide Bridges.

    Published in:
    Applied Sciences (2076-3417), 2019, v. 9, n. 13, p. 2767, doi. 10.3390/app9132767
    By:
    • Chepanova, Arina A.;
    • Mozhaitsev, Evgenii S.;
    • Munkuev, Aldar A.;
    • Suslov, Evgeniy V.;
    • Korchagina, Dina V.;
    • Zakharova, Olga D.;
    • Zakharenko, Alexandra L.;
    • Patel, Jinal;
    • Ayine-Tora, Daniel M.;
    • Reynisson, Jóhannes;
    • Leung, Ivanhoe K. H.;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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