Works by Lavrik, Olga I.
Results: 88
Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy.
- Published in:
- Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 1415, doi. 10.1080/14756366.2018.1509210
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- Publication type:
- Article
Does the XPA–FEN1 Interaction Concern to Nucleotide Excision Repair or Beyond?
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- Biomolecules (2218-273X), 2024, v. 14, n. 7, p. 814, doi. 10.3390/biom14070814
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- Publication type:
- Article
New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition.
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- Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 973, doi. 10.3390/biom11070973
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- Publication type:
- Article
Regulation of Poly(ADP-Ribose) Polymerase 1 Activity by Y-Box-Binding Protein 1.
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- Biomolecules (2218-273X), 2020, v. 10, n. 9, p. 1325, doi. 10.3390/biom10091325
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- Article
Inhibition of abasic site cleavage in bubble DNA by multifunctional protein YB-1.
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- Journal of Molecular Recognition, 2015, v. 28, n. 2, p. 117, doi. 10.1002/jmr.2435
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- Publication type:
- Article
Human and yeast DNA damage recognition complexes bind with high affinity DNA structures mimicking in size transcription bubble.
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- Journal of Molecular Recognition, 2013, v. 26, n. 12, p. 653, doi. 10.1002/jmr.2308
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- Publication type:
- Article
Effect of the multifunctional proteins RPA, YB-1, and XPC repair factor on AP site cleavage by DNA glycosylase NEIL1.
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- Journal of Molecular Recognition, 2012, v. 25, n. 4, p. 224, doi. 10.1002/jmr.2182
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- Publication type:
- Article
RPA repair recognition of DNA containing pyrimidines bearing bulky adducts.
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- Journal of Molecular Recognition, 2008, v. 21, n. 3, p. 154, doi. 10.1002/jmr.877
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- Publication type:
- Article
tRNA discrimination by T. thermophilus phenylalanyl-tRNA synthetase at the binding step.
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- Journal of Molecular Recognition, 2002, v. 15, n. 4, p. 188, doi. 10.1002/jmr.575
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- Publication type:
- Article
Localization of the large subunit of replication factor C near the 5′ end of DNA primers.
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- Journal of Molecular Recognition, 2001, v. 14, n. 4, p. 239, doi. 10.1002/jmr.538
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- Publication type:
- Article
The genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1.
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- BMC Genomics, 2017, v. 18, p. 1, doi. 10.1186/s12864-017-3889-x
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- Publication type:
- Article
Effects of the RNA-Binding Protein Sam68 on Poly(ADP-Ribose)polymerase 1 Activity.
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- Biochemistry (00062979), 2024, v. 89, n. 12/13, p. 2143, doi. 10.1134/S0006297924120046
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- Publication type:
- Article
Use of qPCR to Evaluate Efficiency of the Bulky DNA Damage Removal in Extracts of Mammalian Cells with Different Maximum Lifespan.
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- Biochemistry (00062979), 2024, v. 89, n. 7, p. 1183, doi. 10.1134/S0006297924070022
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- Publication type:
- Article
Activity of DNA Repair Systems in the Cells of Long-Lived Rodents and Bats.
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- Biochemistry (00062979), 2024, v. 89, n. 6, p. 1014, doi. 10.1134/S0006297924060038
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- Publication type:
- Article
Studying Structure and Functions of Nucleosomes with Atomic Force Microscopy.
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- Biochemistry (00062979), 2024, v. 89, n. 4, p. 674, doi. 10.1134/S0006297924040072
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- Publication type:
- Article
Methods for Assessment of Nucleotide Excision Repair Efficiency.
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- Biochemistry (00062979), 2023, v. 88, n. 11, p. 1844, doi. 10.1134/S0006297923110147
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- Publication type:
- Article
Inhibitory Effects of 7-Methylguanine and Its Metabolite 8-Hydroxy-7-Methylguanine on Human Poly(ADP-Ribose) Polymerase 1.
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- Biochemistry (00062979), 2022, v. 87, n. 8, p. 823, doi. 10.1134/S0006297922080132
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- Publication type:
- Article
Study of Interaction of the PARP Family DNA-Dependent Proteins with Nucleosomes Containing DNA Intermediates of the Initial Stages of BER Process.
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- Biochemistry (00062979), 2022, v. 87, n. 4, p. 331, doi. 10.1134/S0006297922040034
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- Publication type:
- Article
Role of YB-1 in Regulation of Poly(ADP-Ribosylation) Catalyzed by Poly(ADP-Ribose) Polymerases.
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- Biochemistry (00062979), 2022, v. 87, n. 1, p. S32, doi. 10.1134/S0006297922140048
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- Publication type:
- Article
Proteins Associated with Neurodegenerative Diseases: Link to DNA Repair.
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- Biomedicines, 2024, v. 12, n. 12, p. 2808, doi. 10.3390/biomedicines12122808
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- Publication type:
- Article
Poly(ADP-ribose)polymerase 1 stimulates the AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1.
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- Bioscience Reports, 2015, v. 35, n. 4, p. 1, doi. 10.1042/BSR20140192
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- Publication type:
- Article
A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts.
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- Cells (2073-4409), 2024, v. 13, n. 4, p. 302, doi. 10.3390/cells13040302
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- Publication type:
- Article
PARP1 Activation Controls Stress Granule Assembly after Oxidative Stress and DNA Damage.
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- Cells (2073-4409), 2022, v. 11, n. 23, p. 3932, doi. 10.3390/cells11233932
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- Publication type:
- Article
The XPA Protein—Life under Precise Control.
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- Cells (2073-4409), 2022, v. 11, n. 23, p. 3723, doi. 10.3390/cells11233723
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- Publication type:
- Article
Inhibition of Transcription Induces Phosphorylation of YB-1 at Ser102 and Its Accumulation in the Nucleus.
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- Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010104
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- Publication type:
- Article
Usnic Acid Derivatives Inhibit DNA Repair Enzymes Tyrosyl-DNA Phosphodiesterases 1 and 2 and Act as Potential Anticancer Agents.
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- Genes, 2023, v. 14, n. 10, p. 1931, doi. 10.3390/genes14101931
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- Publication type:
- Article
The Role of PARP1 and PAR in ATP-Independent Nucleosome Reorganisation during the DNA Damage Response.
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- Genes, 2023, v. 14, n. 1, p. 112, doi. 10.3390/genes14010112
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- Publication type:
- Article
Divalent and multivalent cations control liquid-like assembly of poly(ADP-ribosyl)ated PARP1 into multimolecular associates in vitro.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06811-4
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- Publication type:
- Article
Sulfide, Sulfoxide, and Sulfone Derivatives of Usnic Acid as Inhibitors of Human TDP1 and TDP2 Enzymes.
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- Chemistry (2624-8549), 2024, v. 6, n. 6, p. 1658, doi. 10.3390/chemistry6060101
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- Publication type:
- Article
AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1
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- FEBS Letters, 2011, v. 585, n. 4, p. 683, doi. 10.1016/j.febslet.2011.01.032
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- Article
Photoreactive DNA as a Tool to Study Replication Protein A Functioning in DNA Replication and Repair.
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- Photochemistry & Photobiology, 2020, v. 96, n. 2, p. 440, doi. 10.1111/php.13222
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- Article
Dual function of HPF1 in the modulation of PARP1 and PARP2 activities.
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- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02780-0
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- Article
Apurinic/apyrimidinic endonuclease 1 has major impact in prevention of suicidal covalent DNA–protein crosslink with apurinic/apyrimidinic site in cellular extracts.
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- IUBMB Life, 2024, v. 76, n. 11, p. 987, doi. 10.1002/iub.2890
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- Article
Unrepairable analogous of nucleotide excision repair substrates as a potential anti-cancer drugs.
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- Biopolymers & Cell, 2019, v. 35, n. 3, p. 180, doi. 10.7124/bc.0009B8
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- Article
Detection the specificity of poly(ADP-ribose) polymerase 1 and poly(ADP-ribose) polymerase-2 interaction with DNA strand breaks at single molecule level.
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- Biopolymers & Cell, 2015, p. 30
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- Publication type:
- Article
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interacts with apurinic/apyrimidinic sites in DNA.
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- Biopolymers & Cell, 2015, p. 10
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- Publication type:
- Article
PARP1 and PARP2 catalyze poly(ADP-ribosyl)ation of DNA strand break termini.
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- Biopolymers & Cell, 2015, p. 7
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- Publication type:
- Article
Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors—New Usnic Acid Derivatives.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 1210, doi. 10.3390/ijms25021210
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- Article
Mutant-Huntingtin Molecular Pathways Elucidate New Targets for Drug Repurposing.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 16798, doi. 10.3390/ijms242316798
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- Publication type:
- Article
New 5-Hydroxycoumarin-Based Tyrosyl-DNA Phosphodiesterase I Inhibitors Sensitize Tumor Cell Line to Topotecan.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9155, doi. 10.3390/ijms24119155
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- Article
Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach.
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- 2023
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- Publication type:
- Editorial
Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5781, doi. 10.3390/ijms24065781
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- Publication type:
- Article
Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5148, doi. 10.3390/ijms24065148
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- Publication type:
- Article
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3834, doi. 10.3390/ijms24043834
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- Publication type:
- Article
Poly(ADP-ribose) in Condensates: The PARtnership of Phase Separation and Site-Specific Interactions.
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- 2022
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- Publication type:
- Literature Review
FUS Microphase Separation: Regulation by Nucleic Acid Polymers and DNA Repair Proteins.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13200, doi. 10.3390/ijms232113200
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- Publication type:
- Article
New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11336, doi. 10.3390/ijms222111336
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- Article
Strand Displacement Activity of PrimPol.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 23, p. 9027, doi. 10.3390/ijms21239027
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- Publication type:
- Article
The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7162, doi. 10.3390/ijms21197162
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- Publication type:
- Article
Fused in Sarcoma (FUS) in DNA Repair: Tango with Poly(ADP-ribose) Polymerase 1 and Compartmentalisation of Damaged DNA.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7020, doi. 10.3390/ijms21197020
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- Publication type:
- Article