Works matching AU Lavrik, Inna N.

Results: 38

Pharmacological targeting of caspase-8/c-FLIPL heterodimer enhances complex II assembly and elimination of pancreatic cancer cells.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-024-07409-6

By:

König, Corinna;
Ivanisenko, Nikita V.;
Ivanisenko, Vladimir A.;
Kulms, Dagmar;
Lavrik, Inna N.

Publication type:

Article

The chains of death.

Published in:

Cell Cycle, 2013, v. 12, n. 2, p. 193, doi. 10.4161/cc.23464

By:

Schleich, Kolja;
Krammer, Peter H.;
Lavrik, Inna N.

Publication type:

Article

The role of death domain proteins in host response upon SARS-CoV-2 infection: modulation of programmed cell death and translational applications.

Published in:

Cell Death Discovery, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1038/s41420-020-00331-w

By:

Ivanisenko, Nikita V.;
Seyrek, Kamil;
Kolchanov, Nikolay A.;
Ivanisenko, Vladimir A.;
Lavrik, Inna N.

Publication type:

Article

The Crosstalk of Apoptotic and Non-Apoptotic Signaling in CD95 System.

Published in:

Cells (2073-4409), 2024, v. 13, n. 21, p. 1814, doi. 10.3390/cells13211814

By:

Seyrek, Kamil;
Espe, Johannes;
Reiss, Elisabeth;
Lavrik, Inna N.

Publication type:

Article

RL2 Enhances the Elimination of Breast Cancer Cells by Doxorubicin.

Published in:

Cells (2073-4409), 2023, v. 12, n. 24, p. 2779, doi. 10.3390/cells12242779

By:

Wohlfromm, Fabian;
Seyrek, Kamil;
Ivanisenko, Nikita;
Troitskaya, Olga;
Kulms, Dagmar;
Richter, Vladimir;
Koval, Olga;
Lavrik, Inna N.

Publication type:

Article

Prioritization of genes involved in endothelial cell apoptosis by their implication in lymphedema using an analysis of associative gene networks with ANDSystem.

Published in:

BMC Medical Genomics, 2019, v. 12, n. 2, p. N.PAG, doi. 10.1186/s12920-019-0492-9

By:

Saik, Olga V.;
Nimaev, Vadim V.;
Usmonov, Dilovarkhuja B.;
Demenkov, Pavel S.;
Ivanisenko, Timofey V.;
Lavrik, Inna N.;
Ivanisenko, Vladimir A.

Publication type:

Article

Novel candidate genes important for asthma and hypertension comorbidity revealed from associative gene networks.

Published in:

BMC Medical Genomics, 2018, v. 11, p. 1, doi. 10.1186/s12920-018-0331-4

By:

Saik, Olga V.;
Demenkov, Pavel S.;
Ivanisenko, Timofey V.;
Bragina, Elena Yu;
Freidin, Maxim B.;
Goncharova, Irina A.;
Dosenko, Victor E.;
Zolotareva, Olga I.;
Hofestaedt, Ralf;
Lavrik, Inna N.;
Rogaev, Evgeny I.;
Ivanisenko, Vladimir A.

Publication type:

Article

Delineating the role of c-FLIP/NEMO interaction in the CD95 network via rational design of molecular probes.

Published in:

BMC Genomics, 2019, v. 20, n. 3, p. N.PAG, doi. 10.1186/s12864-019-5539-y

By:

Ivanisenko, Nikita V.;
Buchbinder, Jörn H.;
Espe, Johannes;
Richter, Max;
Bollmann, Miriam;
Hillert, Laura K.;
Ivanisenko, Vladimir A.;
Lavrik, Inna N.

Publication type:

Article

Caspases: pharmacological manipulation of cell death.

Published in:

Journal of Clinical Investigation, 2005, v. 115, n. 10, p. 2665, doi. 10.1172/JCI26252

By:

Lavrik, Inna N.;
Golks, Alexander;
Krammer, Peter H.

Publication type:

Article

Targeting caspase-8/c-FLIPL heterodimer in complex II promotes DL-mediated cell death.

Published in:

Frontiers in Cell & Developmental Biology, 2024, p. 01, doi. 10.3389/fcell.2024.1471216

By:

Hillert-Richter, Laura K.;
König, Corinna;
Ivanisenko, Nikita V.;
Reinhold, Dirk;
Lavrik, Inna N.

Publication type:

Article

Targeting caspase-8/c-FLIP L heterodimer in complex II promotes DL-mediated cell death.

Published in:

Frontiers in Cell & Developmental Biology, 2024, p. 1, doi. 10.3389/fcell.2024.1471216

By:

Hillert-Richter, Laura K.;
König, Corinna;
Ivanisenko, Nikita V.;
Reinhold, Dirk;
Lavrik, Inna N.

Publication type:

Article

Targeting caspase-8/c-FLIPL heterodimer in complex II promotes DL-mediated cell death.

Published in:

Frontiers in Cell & Developmental Biology, 2024, p. 1, doi. 10.3389/fcell.2024.1471216

By:

Hillert-Richter, Laura K.;
König, Corinna;
Ivanisenko, Nikita V.;
Reinhold, Dirk;
Lavrik, Inna N.

Publication type:

Article

Cytotoxic and Antitumor Activity of Lactaptin in Combination with Autophagy Inducers and Inhibitors.

Published in:

BioMed Research International, 2019, p. 1, doi. 10.1155/2019/4087160

By:

Bagamanshina, Anastasia V.;
Troitskaya, Olga S.;
Nushtaeva, Anna A.;
Yunusova, Anastasia Yu;
Starykovych, Marina O.;
Kuligina, Elena V.;
Kit, Yuri Ya;
Richter, Max;
Wohlfromm, Fabian;
Kähne, Thilo;
Lavrik, Inna N.;
Richter, Vladimir A.;
Koval, Olga A.

Publication type:

Article

Life and death in peripheral T cells.

Published in:

Nature Reviews Immunology, 2007, v. 7, n. 7, p. 532, doi. 10.1038/nri2115

By:

Krammer, Peter H.;
Arnold, Rüdiger;
Lavrik, Inna N.

Publication type:

Article

Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes.

Published in:

Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0293-8

By:

Möhle, Luisa;
Schlüter, Dirk;
Dunay, Ildiko Rita;
Montag, Dirk;
Israel, Nicole;
Seifert, Ulrike;
Müller, Andreas;
Paarmann, Kristin;
Krohn, Markus;
Pahnke, Jens;
Pietkiewicz, Sabine;
Lavrik, Inna N.;
Buguliskis, Jeffrey S.;
Gundelfinger, Eckart D.;
Schott, Björn H.

Publication type:

Article

A guide to automated apoptosis detection: How to make sense of imaging flow cytometry data.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197208

By:

Pischel, Dennis;
Buchbinder, Jörn H.;
Sundmacher, Kai;
Lavrik, Inna N.;
Flassig, Robert J.

Publication type:

Article

Oligomerised RIPK1 is the main core component of the CD95 necrosome.

Published in:

EMBO Journal, 2025, v. 44, n. 11, p. 3231, doi. 10.1038/s44318-025-00433-0

By:

Ivanisenko, Nikita V;
König, Corinna;
Hillert-Richter, Laura K;
Feoktistova, Maria A;
Pietkiewicz, Sabine;
Richter, Max;
Panayotova-Dimitrova, Diana;
Kaehne, Thilo;
Lavrik, Inna N

Publication type:

Article

Alterations in the nucleocytoplasmic transport in apoptosis: Caspases lead the way.

Published in:

Cell Proliferation, 2018, v. 51, n. 5, p. N.PAG, doi. 10.1111/cpr.12467

By:

Kopeina, Gelina S.;
Prokhorova, Evgeniia A.;
Lavrik, Inna N.;
Zhivotovsky, Boris

Publication type:

Article

The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities.

Published in:

International Journal of Cancer, 2007, v. 121, n. 8, p. 1839, doi. 10.1002/ijc.22883

By:

Zhu, Jia Y.;
Lavrik, Inna N.;
Mahlknecht, Ulrich;
Giaisi, Marco;
Proksch, Peter;
Krammer, Peter H.;
Li-Weber, Min

Publication type:

Article

Reconstruction of the regulatory hypermethylation network controlling hepatocellular carcinoma development during hepatitis C viral infection.

Published in:

Journal of Integrative Bioinformatics, 2023, v. 20, n. 3, p. 1, doi. 10.1515/jib-2023-0013

By:

Antropova, Evgeniya A.;
Khlebodarova, Tamara M.;
Demenkov, Pavel S.;
Volianskaia, Anastasiia R.;
Venzel, Artur S.;
Ivanisenko, Nikita V.;
Gavrilenko, Alexandr D.;
Ivanisenko, Timofey V.;
Adamovskaya, Anna V.;
Revva, Polina M.;
Kolchanov, Nikolay A.;
Lavrik, Inna N.;
Ivanisenko, Vladimir A.

Publication type:

Article

YB-1 Mediates TNF-Induced Pro-Survival Signaling by Regulating NF-κB Activation.

Published in:

Cancers, 2020, v. 12, n. 8, p. 2188, doi. 10.3390/cancers12082188

By:

Shah, Aneri;
Plaza-Sirvent, Carlos;
Weinert, Sönke;
Buchbinder, Jörn H.;
Lavrik, Inna N.;
Mertens, Peter R.;
Schmitz, Ingo;
Lindquist, Jonathan A.

Publication type:

Article

The Recombinant Fragment of Human κ-Casein Induces Cell Death by Targeting the Proteins of Mitochondrial Import in Breast Cancer Cells.

Published in:

Cancers, 2020, v. 12, n. 6, p. 1427, doi. 10.3390/cancers12061427

By:

Richter, Max;
Wohlfromm, Fabian;
Kähne, Thilo;
Bongartz, Hannes;
Seyrek, Kamil;
Kit, Yuriy;
Chinak, Olga;
Richter, Vladimir A.;
Koval, Olga A.;
Lavrik, Inna N.

Publication type:

Article

Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain.

Published in:

BMC Genomics, 2015, v. 16, p. 1, doi. 10.1186/1471-2164-16-S13-S3

By:

Petrovskiy, Evgeny D.;
Saik, Olga V.;
Tiys, Evgeny S.;
Lavrik, Inna N.;
Kolchanov, Nikolay A.;
Ivanisenko, Vladimir A.

Publication type:

Article

Cdk1/Cyclin B1 Controls Fas-Mediated Apoptosis by Regulating Caspase-8 Activity.

Published in:

Molecular & Cellular Biology, 2010, v. 30, n. 24, p. 11, doi. 10.1128/MCB.00731-10

By:

Matthess, Yves;
Raab, Monika;
Sanhaji, Mourad;
Lavrik, Inna N.;
Strebhardt, Klaus

Publication type:

Article

A New C-Terminal Cleavage Product of Procaspase-8, p30, Defines an Alternative Pathway of Procaspase-8 Activation.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 16, p. 4431, doi. 10.1128/MCB.02261-07

By:

Hoffmann, Julia C.;
Pappa, Alexander;
Krammer, Peter H.;
Lavrik, Inna N.

Publication type:

Article

Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.

Published in:

Cancer Immunology, Immunotherapy, 2008, v. 57, n. 6, p. 871, doi. 10.1007/s00262-007-0423-z

By:

Shebzukhov, Yuriy V.;
Lavrik, Inna N.;
Karbach, Julia;
Khlgatian, Svetlana V.;
Koroleva, Ekaterina P.;
Belousov, Pavel V.;
Kashkin, Kirill N.;
Knuth, Alexander;
Jager, Elke;
Nai-Wen Chi;
Kuprash, Dmitry V.;
Nedospasov, Sergei A.

Publication type:

Article

Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL.

Published in:

Journal of Cell Biology, 2010, v. 190, n. 3, p. 377, doi. 10.1083/jcb.201002060

By:

Fricker, Nicolai;
Beaudouin, Joel;
Richter, Petra;
Eils, Roland;
Krammer, Peter H.;
Lavrik, Inna N.

Publication type:

Article

Apoptosis regulation by subcellular relocation of caspases.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-30652-x

By:

Prokhorova, Evgeniia A.;
Kopeina, Gelina S.;
Lavrik, Inna N.;
Zhivotovsky, Boris

Publication type:

Article

Targeting RIPK1 in AML cells carrying FLT3‐ITD.

Published in:

International Journal of Cancer, 2019, v. 145, n. 6, p. 1558, doi. 10.1002/ijc.32246

By:

Hillert, Laura K.;
Bettermann‐Bethge, Kira;
Nimmagadda, Subbaiah Chary;
Fischer, Thomas;
Naumann, Michael;
Lavrik, Inna N.

Publication type:

Article

A study of structural properties of gene network graphs for mathematical modeling of integrated mosaic gene networks.

Published in:

Journal of Bioinformatics & Computational Biology, 2017, v. 15, n. 2, p. -1, doi. 10.1142/S0219720016500451

By:

Petrovskaya, Olga V.;
Petrovskiy, Evgeny D.;
Lavrik, Inna N.;
Ivanisenko, Vladimir A.

Publication type:

Article

Modulation of CD95-mediated signaling by post-translational modifications: towards understanding CD95 signaling networks.

Published in:

Apoptosis, 2019, v. 24, n. 5/6, p. 385, doi. 10.1007/s10495-019-01540-0

By:

Seyrek, Kamil;
Lavrik, Inna N.

Publication type:

Article

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells.

Published in:

Molecular Systems Biology, 2010, v. 6, n. 1, p. 1, doi. 10.1038/msb.2010.6

By:

Neumann, Leo;
Pforr, Carina;
Beaudouin, Joel;
Pappa, Alexander;
Fricker, Nicolai;
Krammer, Peter H;
Lavrik, Inna N;
Eils, Roland

Publication type:

Article

Quantitative single cell analysis uncovers the life/death decision in CD95 network.

Published in:

PLoS Computational Biology, 2018, v. 14, n. 9, p. 1, doi. 10.1371/journal.pcbi.1006368

By:

Buchbinder, Jörn H.;
Pischel, Dennis;
Sundmacher, Kai;
Flassig, Robert J.;
Lavrik, Inna N.

Publication type:

Article

The cross-talk of autophagy and apoptosis in breast carcinoma: implications for novel therapies?

Published in:

Biochemical Journal, 2022, v. 479, n. 14, p. 1581, doi. 10.1042/BCJ20210676

By:

Seyrek, Kamil;
Wohlfromm, Fabian;
Espe, Johannes;
Lavrik, Inna N.

Publication type:

Article

Pharmacological targeting of c-FLIPL and Bcl-2 family members promotes apoptosis in CD95L-resistant cells.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76079-1

By:

König, Corinna;
Hillert-Richter, Laura K.;
Ivanisenko, Nikita V.;
Ivanisenko, Vladimir A.;
Lavrik, Inna N.

Publication type:

Article

Modulation of the CD95-Induced Apoptosis: The Role of CD95 N-Glycosylation.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019927

By:

Shatnyeva, Olga M.;
Kubarenko, Andriy V.;
Weber, Claudia E. M.;
Pappa, Alexander;
Schwartz-Albiez, Reinhard;
Weber, Alexander N. R.;
Krammer, Peter H.;
Lavrik, Inna N.

Publication type:

Article

Mathematical modeling of apoptosis.

Published in:

Cell Communication & Signaling, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1478-811X-11-44

By:

Schleich, Kolja;
Lavrik, Inna N.

Publication type:

Article

Ally or traitor: the dual role of p62 in caspase-2 regulation.

Published in:

Cell Death & Disease, 2024, v. 15, n. 11, p. 1, doi. 10.1038/s41419-024-07230-3

By:

Volik, Pavel I.;
Zamaraev, Alexey V.;
Egorshina, Aleksandra Y.;
Pervushin, Nikolay V.;
Kapusta, Anastasia A.;
Tyurin-Kuzmin, Pyotr A.;
Lipatova, Anastasia V.;
Kaehne, Thilo;
Lavrik, Inna N.;
Zhivotovsky, Boris;
Kopeina, Gelina S.

Publication type:

Article

Works matching AU Lavrik, Inna N.

Pharmacological targeting of caspase-8/c-FLIP<sub>L</sub> heterodimer enhances complex II assembly and elimination of pancreatic cancer cells.

The chains of death.

The role of death domain proteins in host response upon SARS-CoV-2 infection: modulation of programmed cell death and translational applications.

The Crosstalk of Apoptotic and Non-Apoptotic Signaling in CD95 System.

RL2 Enhances the Elimination of Breast Cancer Cells by Doxorubicin.

Prioritization of genes involved in endothelial cell apoptosis by their implication in lymphedema using an analysis of associative gene networks with ANDSystem.

Novel candidate genes important for asthma and hypertension comorbidity revealed from associative gene networks.

Delineating the role of c-FLIP/NEMO interaction in the CD95 network via rational design of molecular probes.

Caspases: pharmacological manipulation of cell death.

Targeting caspase-8/c-FLIP<sub>L</sub> heterodimer in complex II promotes DL-mediated cell death.

Targeting caspase-8/c-FLIP L heterodimer in complex II promotes DL-mediated cell death.

Targeting caspase-8/c-FLIP<sub>L</sub> heterodimer in complex II promotes DL-mediated cell death.

Cytotoxic and Antitumor Activity of Lactaptin in Combination with Autophagy Inducers and Inhibitors.

Life and death in peripheral T cells.

Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes.

A guide to automated apoptosis detection: How to make sense of imaging flow cytometry data.

Oligomerised RIPK1 is the main core component of the CD95 necrosome.

Alterations in the nucleocytoplasmic transport in apoptosis: Caspases lead the way.

The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities.

Reconstruction of the regulatory hypermethylation network controlling hepatocellular carcinoma development during hepatitis C viral infection.

YB-1 Mediates TNF-Induced Pro-Survival Signaling by Regulating NF-κB Activation.

The Recombinant Fragment of Human κ-Casein Induces Cell Death by Targeting the Proteins of Mitochondrial Import in Breast Cancer Cells.

Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain.

Cdk1/Cyclin B1 Controls Fas-Mediated Apoptosis by Regulating Caspase-8 Activity.

A New C-Terminal Cleavage Product of Procaspase-8, p30, Defines an Alternative Pathway of Procaspase-8 Activation.

Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.

Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIP<sub>L</sub>.

Apoptosis regulation by subcellular relocation of caspases.

Targeting RIPK1 in AML cells carrying FLT3‐ITD.

A study of structural properties of gene network graphs for mathematical modeling of integrated mosaic gene networks.

Modulation of CD95-mediated signaling by post-translational modifications: towards understanding CD95 signaling networks.

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells.

Quantitative single cell analysis uncovers the life/death decision in CD95 network.

The cross-talk of autophagy and apoptosis in breast carcinoma: implications for novel therapies?

Pharmacological targeting of c-FLIP<sub>L</sub> and Bcl-2 family members promotes apoptosis in CD95L-resistant cells.

Modulation of the CD95-Induced Apoptosis: The Role of CD95 N-Glycosylation.

Mathematical modeling of apoptosis.

Ally or traitor: the dual role of p62 in caspase-2 regulation.