Works by Laviolette, Steven R.

Results: 61

Maternal dietary DHA and EPA supplementation ameliorates adverse cardiac outcomes in THC-exposed rat offspring.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-92844-6

By:

Lee, Kendrick;
Sarikahya, Mohammed H.;
Cousineau, Samantha L.;
Yeung, Ken K.-C.;
Lucas, Amica;
Loudon, Kara;
Tomy, Thane;
Tomy, Gregg T.;
Natale, David R. C.;
Laviolette, Steven R.;
Hardy, Daniel B.

Publication type:

Article

Chronic nicotine exposure induces molecular and transcriptomic endophenotypes associated with mood and anxiety disorders in a cerebral organoid neurodevelopmental model.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1473213

By:

Proud, Emma K.;
Rodríguez-Ruiz, Mar;
Gummerson, Dana M.;
Vanin, Sebastian;
Hardy, Daniel B.;
Rushlow, Walter J.;
Laviolette, Steven R.

Publication type:

Article

Exploring the impact of adolescent exposure to cannabinoids and nicotine on psychiatric risk: insights from translational animal models.

Published in:

Psychological Medicine, 2021, v. 51, n. 6, p. 940, doi. 10.1017/S0033291719003325

By:

Laviolette, Steven R.

Publication type:

Article

Cannabidiol Counteracts the Psychotropic Side-Effects of Δ-9-Tetrahydrocannabinol in the Ventral Hippocampus through Bidirectional Control of ERK1-2 Phosphorylation.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 44, p. 8762, doi. 10.1523/JNEUROSCI.0708-19.2019

By:

Hudson, Roger;
Renard, Justine;
Norris, Christopher;
Rushlow, Walter J.;
Laviolette, Steven R.

Publication type:

Article

The Role of Cholinergic Midbrain Neurons in Startle and Prepulse Inhibition.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 41, p. 8798, doi. 10.1523/JNEUROSCI.0984-18.2018

By:

Azzopardi, Erin;
Louttit, Andrea G.;
DeOliveira, Cleusa;
Laviolette, Steven R.;
Schmid, Susanne

Publication type:

Article

Fear Memory Recall Potentiates Opiate Reward Sensitivity through Dissociable Dopamine D1 versus D4 Receptor-Dependent Memory Mechanisms in the Prefrontal Cortex.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 19, p. 4543, doi. 10.1523/JNEUROSCI.3113-17.2018

By:

Jing Jing Li;
Szkudlarek, Hanna;
Renard, Justine;
Hudson, Roger;
Rushlow, Walter;
Laviolette, Steven R.

Publication type:

Article

Cannabidiol Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway through a Novel mTOR/p70S6 Kinase Signaling Pathway.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 18, p. 5160, doi. 10.1523/JNEUROSCI.3387-15.2016

By:

Renard, Justine;
Loureiro, Michael;
Rosen, Laura G.;
Zunder, Jordan;
de Oliveira, Cleusa;
Schmid, Susanne;
Rushlow, Walter J.;
Laviolette, Steven R.

Publication type:

Article

Cannabinoid Transmission in the Prefrontal Cortex Bi-Phasically Controls Emotional Memory Formation via Functional Interactions with the Ventral Tegmental Area.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 39, p. 13096, doi. 10.1523/JNEUROSCI.1297-14.2014

By:

Draycott, Brittany;
Loureiro, Michael;
Ahmad, Tasha;
Tan, Huibing;
Zunder, Jordan;
Laviolette, Steven R.

Publication type:

Article

Understanding the Association of Childhood Tobacco Use With Neuropathological Outcomes and Cognitive Performance Deficits in Vulnerable Brains.

Published in:

2022

By:

Laviolette, Steven R.

Publication type:

Opinion

Cannabinoids Potentiate Emotional Learning Plasticity in Neurons of the Medial Prefrontal Cortex through Basolateral Amygdala Inputs.

Published in:

2006

By:

Laviolette, Steven R.;
Grace, Anthony A.

Publication type:

Abstract

A Subpopulation of Neurons in the Medial Prefrontal Cortex Encodes Emotional Learning with Burst and Frequency Codes through a Dopamine D4 Receptor-Dependent Basolateral Amygdala Input.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 26, p. 6066, doi. 10.1523/JNEUROSCI.1168-05.2005

By:

Laviolette, Steven R.;
Lipski, Witold J.;
Grace, Anthony A.

Publication type:

Article

Dopamine Modulation of Emotional Processing in Cortical and Subcortical Neural Circuits: Evidence for a Final Common Pathway in Schizophrenia?

Published in:

Schizophrenia Bulletin, 2007, v. 33, n. 4, p. 971, doi. 10.1093/schbul/sbm048

By:

Laviolette, Steven R.

Publication type:

Article

L-Theanine Prevents Long-Term Affective and Cognitive Side Effects of Adolescent D-9-Tetrahydrocannabinol Exposure and Blocks Associated Molecular and Neuronal Abnormalities in the Mesocorticolimbic Circuitry.

Published in:

Journal of Neuroscience, 2021, v. 41, n. 4, p. 739, doi. 10.1523/JNEUROSCI.1050-20.2020

By:

De Felice, Marta;
Renard, Justine;
Hudson, Roger;
Szkudlarek, Hanna J.;
Pereira, Brian J.;
Schmid, Susanne;
Rushlow, Walter J.;
Laviolette, Steven R.

Publication type:

Article

Reversing the Psychiatric Effects of Neurodevelopmental Cannabinoid Exposure: Exploring Pharmacotherapeutic Interventions for Symptom Improvement.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 7861, doi. 10.3390/ijms22157861

By:

De Felice, Marta;
Laviolette, Steven R.

Publication type:

Article

In Utero Exposure to Δ9-Tetrahydrocannabinol Leads to Postnatal Catch-Up Growth and Dysmetabolism in the Adult Rat Liver.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7502, doi. 10.3390/ijms22147502

By:

Oke, Shelby L.;
Lee, Kendrick;
Papp, Rosemary;
Laviolette, Steven R.;
Hardy, Daniel B.

Publication type:

Article

Oxytocin Signaling as a Target to Block Social Defeat-Induced Increases in Drug Abuse Reward.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2372, doi. 10.3390/ijms22052372

By:

Ferrer-Pérez, Carmen;
Reguilón, Marina D.;
Miñarro, José;
Rodríguez-Arias, Marta;
Laviolette, Steven R.

Publication type:

Article

What Can Rats Tell Us about Adolescent Cannabis Exposure? Insights from Preclinical Research.

Published in:

2016

By:

Renard, Justine;
Rushlow, Walter J.;
Laviolette, Steven R.

Publication type:

journal article

Growing up high: Understanding the impacts of adolescent cannabis use on mental health and brain development.

Published in:

University of Toronto Medical Journal, 2019, v. 96, n. 3, p. 78

By:

Laviolette, Steven R.

Publication type:

Article

GABAA receptors in the ventral tegmental area control bidirectional reward signalling between dopaminergic and non-dopaminergic neural motivational systems.

Published in:

European Journal of Neuroscience, 2001, v. 13, n. 5, p. 1009, doi. 10.1046/j.1460-9568.2001.01458.x

By:

Laviolette, Steven R.;
Van Der Kooy, Derek

Publication type:

Article

Endogenous Opioid-Induced Neuroplasticity of Dopaminergic Neurons in the Ventral Tegmental Area Influences Natural and Opiate Reward.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 26, p. 8825, doi. 10.1523/JNEUROSCI.0133-14.2014

By:

Pitchers, Kyle K.;
Coppens, Caroline M.;
Beloate, Lauren N.;
Fuller, Jonathan;
Van, Sandy;
Frohmader, Karla S.;
Laviolette, Steven R.;
Lehman, Michael N.;
Coolen, Lique M.

Publication type:

Article

Cannabinoid Transmission in the Prelimbic Cortex Bidirectionally Controls Opiate Reward and Aversion Signaling through Dissociable Kappa Versus μ-Opiate Receptor Dependent Mechanisms.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 39, p. 15642, doi. 10.1523/JNEUROSCI.1686-13.2013

By:

Ahmad, Tasha;
Lauzon, Nicole M.;
De Jaeger, Xavier;
Laviolette, Steven R.

Publication type:

Article

Opiate Exposure and Withdrawal Induces a Molecular Memory Switch in the Basolateral Amygdala between ERK1/2 and CaMKIIα-Dependent Signaling Substrates.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 37, p. 14693, doi. 10.1523/JNEUROSCI.1226-13.2013

By:

Lyons, Danika;
de Jaeger, Xavier;
Rosen, Laura G.;
Ahmad, Tasha;
Lauzon, Nicole M.;
Zunder, Jordan;
Coolen, Lique M.;
Rushlow, Walter;
Laviolette, Steven R.

Publication type:

Article

Natural and Drug Rewards Act on Common Neural Plasticity Mechanisms with ΔAFosB as a Key Mediator.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 8, p. 3434, doi. 10.1523/JNEUROSCI.4881-12.2013

By:

Pitchers, Kyle K.;
Vialou, Vincent;
Nestler, Eric J.;
Laviolette, Steven R.;
Lehman, Michael N.;
Coolen, Lique M.

Publication type:

Article

Concurrent Exposure to Methamphetamine and Sexual Behavior Enhances Subsequent Drug Reward and Causes Compulsive Sexual Behavior in Male Rats.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 45, p. 16473, doi. 10.1523/JNEUROSCI.4013-11.2011

By:

Frohmader, Karla S.;
Lehman, Michael N.;
Laviolette, Steven R.;
Coolen, Lique M.

Publication type:

Article

Identification of a Dopamine Receptor-Mediated Opiate Reward Memory Switch in the Basolateral Amygdala-Nucleus Accumbens Circuit.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 31, p. 11172, doi. 10.1523/JNEUROSCI.1781-11.2011

By:

Lintas, Alessandra;
Ning Chi;
Lauzon, Nicole M.;
Bishop, Stephanie F.;
Gholizadeh, Shervin;
Ninglei Sun;
Huibing Tan;
Laviolette, Steven R.

Publication type:

Article

Cannabinoid Transmission in the Basolateral Amygdala Modulates Fear Memory Formation via Functional Inputs to the Prelimbic Cortex.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 14, p. 5300, doi. 10.1523/JNEUROSCI.4718-10.2011

By:

Huibing Tan;
Lauzon, Nicole M.;
Bishop, Stephanie F.;
Ning Chi;
Bechard, Melanie;
Laviolette, Steven R.

Publication type:

Article

Dopamine D1 versus D4 Receptors Differentially Modulate the Encoding of Salient versus Nonsalient Emotional Information in the Medial Prefrontal Cortex.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 15, p. 4836, doi. 10.1523/JNEUROSCI.0178-09.2009

By:

Lauzon, Nicole M.;
Bishop, Stephanie F.;
Laviolette, Steven R.

Publication type:

Article

Dopamine Signaling through D1-Like versus D2-Like Receptors in the Nucleus Accumbens Core versus Shell Differentially Modulates Nicotine Reward Sensitivity.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 32, p. 8025, doi. 10.1523/JNEUROSCI.1371-08.2008

By:

Laviolette, Steven R.;
Lauzon, Nicole M.;
Bishop, Stephanie F.;
Ninglei Sun;
Huibing Tan

Publication type:

Article

Hippocampal Cannabinoid Transmission Modulates Dopamine Neuron Activity: Impact on Rewarding Memory Formation and Social Interaction.

Published in:

Neuropsychopharmacology, 2015, v. 40, n. 6, p. 1436, doi. 10.1038/npp.2014.329

By:

Loureiro, Michael;
Renard, Justine;
Zunder, Jordan;
Laviolette, Steven R

Publication type:

Article

Dopamine Receptor Blockade Modulates the Rewarding and Aversive Properties of Nicotine via Dissociable Neuronal Activity Patterns in the Nucleus Accumbens.

Published in:

Neuropsychopharmacology, 2015, v. 40, n. 3, p. 791, doi. 10.1038/npp.2014.289

By:

Sun, Ninglei;
Laviolette, Steven R

Publication type:

Article

Dopamine Receptor Blockade Modulates the Rewarding and Aversive Properties of Nicotine via Dissociable Neuronal Activity Patterns in the Nucleus Accumbens.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 12, p. 2799, doi. 10.1038/npp.2014.130

By:

Sun, Ninglei;
Laviolette, Steven R

Publication type:

Article

The Bivalent Rewarding and Aversive properties of Δ9-tetrahydrocannabinol are Mediated Through Dissociable Opioid Receptor Substrates and Neuronal Modulation Mechanisms in Distinct Striatal Sub-Regions.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46215-7

By:

Norris, Christopher;
Szkudlarek, Hanna J.;
Pereira, Brian;
Rushlow, Walter;
Laviolette, Steven R.

Publication type:

Article

Prenatal Cannabinoid Exposure: Emerging Evidence of Physiological and Neuropsychiatric Abnormalities.

Published in:

Frontiers in Psychiatry, 2021, v. 11, p. N.PAG, doi. 10.3389/fpsyt.2020.624275

By:

Nashed, Mina G.;
Hardy, Daniel B.;
Laviolette, Steven R.

Publication type:

Article

Inhibition of fatty acid binding protein-5 in the basolateral amygdala induces anxiolytic effects and accelerates fear memory extinction.

Published in:

Psychopharmacology, 2024, v. 241, n. 1, p. 119, doi. 10.1007/s00213-023-06468-7

By:

Jones, Matthew J.;
Uzuneser, Taygun C.;
Clement, Timothy;
Wang, Hehe;
Ojima, Iwao;
Rushlow, Walter J.;
Laviolette, Steven R.

Publication type:

Article

Anxiety and cognitive-related effects of Δ 9-tetrahydrocannabinol (THC) are differentially mediated through distinct GSK-3 vs. Akt-mTOR pathways in the nucleus accumbens of male rats.

Published in:

Psychopharmacology, 2022, v. 239, n. 2, p. 509, doi. 10.1007/s00213-021-06029-w

By:

Hudson, Roger;
Norris, Christopher;
Szkudlarek, Hanna J.;
Khan, Dinat;
Schmid, Susanne;
Rushlow, Walter J.;
Laviolette, Steven R.

Publication type:

Article

Phytocannabinoids modulate emotional memory processing through interactions with the ventral hippocampus and mesolimbic dopamine system: implications for neuropsychiatric pathology.

Published in:

Psychopharmacology, 2018, v. 235, n. 2, p. 447, doi. 10.1007/s00213-017-4766-7

By:

Hudson, Roger;
Rushlow, Walter;
Laviolette, Steven R.

Publication type:

Article

Adolescent Cannabinoid Exposure Induces a Persistent Sub-Cortical Hyper-Dopaminergic State and Associated Molecular Adaptations in the Prefrontal Cortex.

Published in:

Cerebral Cortex, 2017, v. 27, n. 2, p. 1297, doi. 10.1093/cercor/bhv335

By:

Renard, Justine;
Rosen, Laura G.;
Loureiro, Michael;
De Oliveira, Cleusa;
Schmid, Susanne;
Rushlow, Walter J.;
Laviolette, Steven R.

Publication type:

Article

Dopamine D4 Receptor Transmission in the Prefrontal Cortex Controls the Salience of Emotional Memory via Modulation of Calcium Calmodulin–Dependent Kinase II.

Published in:

Cerebral Cortex, 2012, v. 22, n. 11, p. 2486, doi. 10.1093/cercor/bhr326

By:

Lauzon, Nicole M.;
Ahmad, Tasha;
Laviolette, Steven R.

Publication type:

Article

Acquisition, Extinction, and Recall of Opiate Reward Memory Are Signaled by Dynamic Neuronal Activity Patterns in the Prefrontal Cortex.

Published in:

Cerebral Cortex, 2011, v. 21, n. 12, p. 2665, doi. 10.1093/cercor/bhr031

By:

Sun, Ninglei;
Chi, Ning;
Lauzon, Nicole;
Bishop, Stephanie;
Tan, Huibing;
Laviolette, Steven R.

Publication type:

Article

NMDA Receptor Hypofunction in the Prelimbic Cortex Increases Sensitivity to the Rewarding Properties of Opiates via Dopaminergic and Amygdalar Substrates.

Published in:

Cerebral Cortex, 2011, v. 21, n. 1, p. 68, doi. 10.1093/cercor/bhq060

By:

Bishop, Stephanie F.;
Lauzon, Nicole M.;
Bechard, Melanie;
Gholizadeh, Shervin;
Laviolette, Steven R.

Publication type:

Article

Integrated Cannabinoid CB1 Receptor Transmission within the Amygdala–Prefrontal Cortical Pathway Modulates Neuronal Plasticity and Emotional Memory Encoding.

Published in:

Cerebral Cortex, 2010, v. 20, n. 6, p. 1486, doi. 10.1093/cercor/bhp210

By:

Tan, Huibing;
Lauzon, Nicole M.;
Bishop, Stephanie F.;
Bechard, Melanie A.;
Laviolette, Steven R.

Publication type:

Article

Functional interactions between cannabinoids, omega‐3 fatty acids, and peroxisome proliferator‐activated receptors: Implications for mental health pharmacotherapies.

Published in:

European Journal of Neuroscience, 2022, v. 55, n. 4, p. 1088, doi. 10.1111/ejn.15023

By:

Jung, Tony;
Hudson, Roger;
Rushlow, Walter;
Laviolette, Steven R.

Publication type:

Article

Functional interactions between cannabinoids, omega‐3 fatty acids, and peroxisome proliferator‐activated receptors: Implications for mental health pharmacotherapies.

Published in:

European Journal of Neuroscience, 2022, v. 55, n. 3, p. 1088, doi. 10.1111/ejn.15023

By:

Jung, Tony;
Hudson, Roger;
Rushlow, Walter;
Laviolette, Steven R.

Publication type:

Article

Delta‐9‐tetrahydrocannabinol potentiates fear memory salience through functional modulation of mesolimbic dopaminergic activity states.

Published in:

European Journal of Neuroscience, 2018, v. 47, n. 11, p. 1385, doi. 10.1111/ejn.13951

By:

Fitoussi, Aurelie;
Zunder, Jordan;
Tan, Huibing;
Laviolette, Steven R.

Publication type:

Article

Molecular and neuronal plasticity mechanisms in the amygdala-prefrontal cortical circuit: implications for opiate addiction memory formation.

Published in:

Frontiers in Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnins.2015.00399

By:

Rosen, Laura G.;
Ninglei Sun;
Rushlow, Walter;
Laviolette, Steven R.

Publication type:

Article

THE NEUROBIOLOGY OF NICOTINE ADDICTION: BRIDGING THE GAP FROM MOLECULES TO BEHAVIOUR.

Published in:

Nature Reviews Neuroscience, 2004, v. 5, n. 1, p. 55, doi. 10.1038/nrn1298

By:

Laviolette, Steven R.;
Van Der Kooy, Derek

Publication type:

Article

Effects of Adolescent THC Exposure on the Prefrontal GABAergic System: Implications for Schizophrenia-Related Psychopathology.

Published in:

Frontiers in Psychiatry, 2018, p. N.PAG, doi. 10.3389/fpsyt.2018.00281

By:

Renard, Justine;
Rushlow, Walter J.;
Laviolette, Steven R.

Publication type:

Article

Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats.

Published in:

Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00343

By:

Peres, Fernanda F.;
Levin, Raquel;
Suiama, Mayra A.;
Diana, Mariana C.;
Gouvêa, Douglas A.;
Almeida, Valéria;
Santos, Camila M.;
Lungato, Lisandro;
Zuardi, Antônio W.;
Hallak, Jaime E. C.;
Crippa, José A.;
D'Almeida, Vânia;
Silva, Regina H.;
Abílio, Vanessa C.;
Laviolette, Steven R.;
Pytka, Karolina

Publication type:

Article

Opiate state controls bi-directional reward signaling via GABAA receptors in the ventral tegmental area.

Published in:

Nature Neuroscience, 2004, v. 7, n. 2, p. 160, doi. 10.1038/nn1182

By:

Laviolette, Steven R;
Gallegos, Roger A;
Steven J Henriksen, Roger A;
Der Kooy, Derek Van

Publication type:

Article

Adolescent nicotine induces depressive and anxiogenic effects through ERK 1-2 and Akt-GSK-3 pathways and neuronal dysregulation in the nucleus accumbens.

Published in:

2021

By:

Hudson, Roger;
Green, Matthew;
Wright, Daniel J.;
Renard, Justine;
Jobson, Christina E.L.;
Jung, Tony;
Rushlow, Walter;
Laviolette, Steven R.

Publication type:

journal article