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Works matching AU Lauwers, Heleen

Results: 4

1

Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 28, p. 1, doi. 10.1002/anie.202506954

By:

Chen, Yong;
De Lombaerde, Emily;
Bugler‐Lamb, Aimée;
Zhong, Zifu;
Schuijs, Martijn J.;
Gomez, Claudia M. Brenis;
De Baere, Jamie;
Gontsarik, Mark;
Lauwers, Heleen;
Deswarte, Kim;
Sanders, Niek N.;
Lambrecht, Bart N.;
Guilliams, Martin;
De Geest, Bruno G.

Publication type:

Article

2

Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

Published in:

Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202506954

By:

Chen, Yong;
De Lombaerde, Emily;
Bugler‐Lamb, Aimée;
Zhong, Zifu;
Schuijs, Martijn J.;
Gomez, Claudia M. Brenis;
De Baere, Jamie;
Gontsarik, Mark;
Lauwers, Heleen;
Deswarte, Kim;
Sanders, Niek N.;
Lambrecht, Bart N.;
Guilliams, Martin;
De Geest, Bruno G.

Publication type:

Article

3

Lipid Nanoparticle Delivery Alters the Adjuvanticity of the TLR9 Agonist CpG by Innate Immune Activation in Lymphoid Tissue.

Published in:

Advanced Healthcare Materials, 2023, v. 12, n. 32, p. 1, doi. 10.1002/adhm.202301687

By:

Zhong, Zifu;
Chen, Yong;
Deswarte, Kim;
Lauwers, Heleen;
De Lombaerde, Emily;
Cui, Xiaole;
Van Herck, Simon;
Ye, Tingting;
Gontsarik, Mark;
Lienenklaus, Stefan;
Sanders, Niek N.;
Lambrecht, Bart N.;
De Koker, Stefaan;
De Geest, Bruno G.

Publication type:

Article

4

Combinatorial Screening of Biscarbamate Ionizable Lipids Identifies a Low Reactogenicity Lipid for Lipid Nanoparticle mRNA Delivery.

Published in:

Advanced Functional Materials, 2024, v. 34, n. 21, p. 1, doi. 10.1002/adfm.202310623

By:

De Lombaerde, Emily;
Chen, Yong;
Ye, Tingting;
Deckers, Julie;
Mencarelli, Giulia;
De Swarte, Kim;
Lauwers, Heleen;
De Coen, Ruben;
Kasmi, Sabah;
Bevers, Sanne;
Kuchmiy, Anna;
Bogaert, Bram;
Baekens, Lies;
Zhong, Zifu;
Lamoot, Alexander;
Sanders, Niek N.;
Lambrecht, Bart N.;
Baptista, Antonio P.;
De Koker, Stefaan;
De Geest, Bruno G.

Publication type:

Article