KA‐104, a new multitargeted anticonvulsant with potent antinociceptive activity in preclinical models.
- Published in:
- Epilepsia (Series 4), 2020, v. 61, n. 10, p. 2119, doi. 10.1111/epi.16669
- By:
- Publication type:
- Article
Works matching AU Latacz, Gniewomir
Results: 54
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New Phenylglycinamide Derivatives with Hybrid Structure as Candidates for New Broad-Spectrum Anticonvulsants.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 12, p. 1862, doi. 10.3390/cells11121862
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- Publication type:
- Article
3
Pharmaceutical and Safety Profile Evaluation of Novel Selenocompounds with Noteworthy Anticancer Activity.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 2, p. 367, doi. 10.3390/pharmaceutics14020367
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- Publication type:
- Article
4
Guanidines: Synthesis of Novel Histamine H 3 R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect.
- Published in:
- Pharmaceuticals (14248247), 2023, v. 16, n. 5, p. 675, doi. 10.3390/ph16050675
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- Publication type:
- Article
5
Histamine H 3 Receptor Ligands—KSK-59 and KSK-73—Reduce Body Weight Gain in a Rat Model of Excessive Eating.
- Published in:
- Pharmaceuticals (14248247), 2021, v. 14, n. 11, p. 1080, doi. 10.3390/ph14111080
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- Publication type:
- Article
6
Salsolinol—neurotoxic or Neuroprotective?
- Published in:
- Neurotoxicity Research, 2020, v. 37, n. 2, p. 286, doi. 10.1007/s12640-019-00118-7
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- Publication type:
- Article
7
Biotransformation of new racemic (R,S)-5-benzylhydantoin derivatives by D-hydantoinases from adzuki bean.
- Published in:
- Biocatalysis & Biotransformation, 2014, v. 32, n. 2, p. 117, doi. 10.3109/10242422.2014.893578
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- Publication type:
- Article
8
Chalcogen-Varied Imidazolone Derivatives as Antibiotic Resistance Breakers in Staphylococcus aureus Strains.
- Published in:
- Antibiotics (2079-6382), 2023, v. 12, n. 11, p. 1618, doi. 10.3390/antibiotics12111618
- By:
- Publication type:
- Article
9
Manifestations of Liver Impairment and the Effects of MH-76, a Non-Quinazoline α1-Adrenoceptor Antagonist, and Prazosin on Liver Tissue in Fructose-Induced Metabolic Syndrome.
- Published in:
- Metabolites (2218-1989), 2023, v. 13, n. 11, p. 1130, doi. 10.3390/metabo13111130
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- Publication type:
- Article
10
Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats.
- Published in:
- Drug Design, Development & Therapy, 2016, v. 10, p. 3879, doi. 10.2147/DDDT.S116192
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- Publication type:
- Article
11
Low-Basicity 5-HT 6 Receptor Ligands from the Group of Cyclic Arylguanidine Derivatives and Their Antiproliferative Activity Evaluation.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 19, p. 10287, doi. 10.3390/ijms251910287
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- Publication type:
- Article
12
AR71, Histamine H 3 Receptor Ligand—In Vitro and In Vivo Evaluation (Anti-Inflammatory Activity, Metabolic Stability, Toxicity, and Analgesic Action).
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 15, p. 8035, doi. 10.3390/ijms25158035
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- Publication type:
- Article
13
Systematic-Narrative Hybrid Literature Review: Crosstalk between Gastrointestinal Renin–Angiotensin and Dopaminergic Systems in the Regulation of Intestinal Permeability by Tight Junctions.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 10, p. 5566, doi. 10.3390/ijms25105566
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- Publication type:
- Article
14
Anti-Inflammatory Activities of 8-Benzylaminoxanthines Showing High Adenosine A 2A and Dual A 1 /A 2A Receptor Affinity.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13707, doi. 10.3390/ijms241813707
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- Publication type:
- Article
15
In Vivo and In Vitro Characterization of Close Analogs of Compound KA-11, a New Antiseizure Drug Candidate.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 8302, doi. 10.3390/ijms24098302
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- Publication type:
- Article
16
Design, Synthesis and Biological Evaluation of Novel 1,3,5-Triazines: Effect of Aromatic Ring Decoration on Affinity to 5-HT 7 Receptor.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13308, doi. 10.3390/ijms232113308
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- Publication type:
- Article
17
Serotonin 5-HT 6 Receptor Ligands and Butyrylcholinesterase Inhibitors Displaying Antioxidant Activity—Design, Synthesis and Biological Evaluation of Multifunctional Agents against Alzheimer's Disease.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9443, doi. 10.3390/ijms23169443
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- Publication type:
- Article
18
2-{5-[(Z ,2 Z)-2-Chloro-3-(4-nitrophenyl)-2-propenylidene]-4-oxo-2-thioxothiazolidin-3-yl}-3-methylbutanoic Acid as a Potential Anti-Breast Cancer Molecule.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 8, p. 4091, doi. 10.3390/ijms23084091
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- Publication type:
- Article
19
Identification of New Compounds with Anticonvulsant and Antinociceptive Properties in a Group of 3-substituted (2,5-dioxo-pyrrolidin-1-yl)(phenyl)-Acetamides.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 13092, doi. 10.3390/ijms222313092
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- Publication type:
- Article
20
The Phenoxyalkyltriazine Antagonists for 5-HT 6 Receptor with Promising Procognitive and Pharmacokinetic Properties In Vivo in Search for a Novel Therapeutic Approach to Dementia Diseases.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10773, doi. 10.3390/ijms221910773
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- Publication type:
- Article
21
Molecular Insights into an Antibiotic Enhancer Action of New Morpholine-Containing 5-Arylideneimidazolones in the Fight against MDR Bacteria.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 2062, doi. 10.3390/ijms22042062
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- Publication type:
- Article
22
Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 24, p. 9693, doi. 10.3390/ijms21249693
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- Publication type:
- Article
23
The Search for New Anticonvulsants in a Group of (2,5-Dioxopyrrolidin-1-yl)(phenyl)Acetamides with Hybrid Structure—Synthesis and In Vivo/In Vitro Studies.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8780, doi. 10.3390/ijms21228780
- By:
- Publication type:
- Article
24
Dual Target Ligands with 4-tert-Butylphenoxy Scaffold as Histamine H3 Receptor Antagonists and Monoamine Oxidase B Inhibitors.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 10, p. 3411, doi. 10.3390/ijms21103411
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- Publication type:
- Article
25
The 1,3,5-Triazine Derivatives as Innovative Chemical Family of 5-HT6 Serotonin Receptor Agents with Therapeutic Perspectives for Cognitive Impairment.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 14, p. 3420, doi. 10.3390/ijms20143420
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- Publication type:
- Article
26
Studies on Anticonvulsant Effects of Novel Histamine H3R Antagonists in Electrically and Chemically Induced Seizures in Rats.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 11, p. 3386, doi. 10.3390/ijms19113386
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- Publication type:
- Article
27
Antinociceptive effects of novel histamine H<sub>3</sub> and H<sub>4</sub> receptor antagonists and their influence on morphine analgesia of neuropathic pain in the mouse.
- Published in:
- 2018
- By:
- Publication type:
- journal article
28
Correction to: Salsolinol Protects SH-SY5Y Cells Against MPP<sup>+</sup> Damage and Increases Enteric S100‐Immunoreactivity in Wistar Rats.
- Published in:
- 2023
- By:
- Publication type:
- Correction Notice
29
Salsolinol Protects SH-SY5Y Cells Against MPP<sup>+</sup> Damage and Increases Enteric S100-Immunoreactivity in Wistar Rats.
- Published in:
- Neurochemical Research, 2023, v. 48, n. 5, p. 1347, doi. 10.1007/s11064-022-03835-2
- By:
- Publication type:
- Article
30
Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.
- Published in:
- Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202420510
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- Publication type:
- Article
31
Novel, Dual Target‐Directed Annelated Xanthine Derivatives Acting on Adenosine Receptors and Monoamine Oxidase B.
- Published in:
- ChemMedChem, 2020, v. 15, n. 9, p. 772, doi. 10.1002/cmdc.201900717
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- Publication type:
- Article
32
Synthesis and Analgesic Activity of Annelated Xanthine Derivatives in Experimental Models in Rodents.
- Published in:
- Archiv der Pharmazie, 2015, v. 348, n. 10, p. 704, doi. 10.1002/ardp.201500169
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- Publication type:
- Article
33
Study on the effect of EMD386088, a 5-HT receptor partial agonist, in enhancing the anti-immobility action of some antidepressants in rats.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2018, v. 391, n. 1, p. 37, doi. 10.1007/s00210-017-1431-y
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- Publication type:
- Article
34
Aspects of a Distinct Cytotoxicity of Selenium Salts and Organic Selenides in Living Cells with Possible Implications for Drug Design.
- Published in:
- Molecules, 2015, v. 20, n. 8, p. 13894, doi. 10.3390/molecules200813894
- By:
- Publication type:
- Article
35
The Inhibitory Effect of Human Plasma Albumin and Haptoglobin on Platelet Aggregation and 5-HT Release.
- Published in:
- Folia Medica Cracoviensia, 2022, v. 62, n. 3, p. 5, doi. 10.24425/fmc.2022.142365
- By:
- Publication type:
- Article
36
Synthesis and biological profiling of novel isocoumarin derivatives and related compounds.
- Published in:
- Journal of the Serbian Chemical Society, 2021, v. 86, n. 7/8, p. 639, doi. 10.2298/JSC201201025S
- By:
- Publication type:
- Article
37
The Stereoselectivity and Hydrolysis Efficiency of Recombinant d-Hydantoinase from Vigna angularis Against 5-Benzylhydantoin Derivatives with Halogen and Methyl Substituents.
- Published in:
- Applied Biochemistry & Biotechnology, 2015, v. 175, n. 2, p. 698, doi. 10.1007/s12010-014-1313-4
- By:
- Publication type:
- Article
38
Structure−Activity Relationship and Solubility Studies of N1‐Substituted Quinoxaline‐2,3‐diones as Kainate Receptor Antagonists.
- Published in:
- ChemMedChem, 2023, v. 18, n. 18, p. 1, doi. 10.1002/cmdc.202300278
- By:
- Publication type:
- Article
39
Computer‐Aided Search for 5‐Arylideneimidazolone Anticancer Agents Able To Overcome ABCB1‐Based Multidrug Resistance.
- Published in:
- ChemMedChem, 2021, v. 16, n. 15, p. 2386, doi. 10.1002/cmdc.202100252
- By:
- Publication type:
- Article
40
Trisubstituted 1,3,5-Triazines as Histamine H 4 Receptor Antagonists with Promising Activity In Vivo.
- Published in:
- Molecules, 2023, v. 28, n. 10, p. 4199, doi. 10.3390/molecules28104199
- By:
- Publication type:
- Article
41
New Triazine Derivatives as Serotonin 5-HT 6 Receptor Ligands.
- Published in:
- Molecules, 2023, v. 28, n. 3, p. 1108, doi. 10.3390/molecules28031108
- By:
- Publication type:
- Article
42
Benzophenone Derivatives with Histamine H 3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.
- Published in:
- Molecules, 2023, v. 28, n. 1, p. 238, doi. 10.3390/molecules28010238
- By:
- Publication type:
- Article
43
New, Eco-Friendly Method for Synthesis of 3-Chlorophenyl and 1,1′-Biphenyl Piperazinylhexyl Trazodone Analogues with Dual 5-HT 1A /5-HT 7 Affinity and Its Antidepressant-like Activity.
- Published in:
- Molecules, 2022, v. 27, n. 21, p. 7270, doi. 10.3390/molecules27217270
- By:
- Publication type:
- Article
44
Phenylalanine-Based AMPA Receptor Antagonist as the Anticonvulsant Agent with Neuroprotective Activity—In Vitro and In Vivo Studies.
- Published in:
- Molecules, 2022, v. 27, n. 3, p. 875, doi. 10.3390/molecules27030875
- By:
- Publication type:
- Article
45
N -Skatyltryptamines—Dual 5-HT 6 R/D 2 R Ligands with Antipsychotic and Procognitive Potential.
- Published in:
- Molecules, 2021, v. 26, n. 15, p. 4605, doi. 10.3390/molecules26154605
- By:
- Publication type:
- Article
46
Phenylpiperazine 5,5-Dimethylhydantoin Derivatives as First Synthetic Inhibitors of Msr(A) Efflux Pump in Staphylococcus epidermidis.
- Published in:
- Molecules, 2020, v. 25, n. 17, p. 3788, doi. 10.3390/molecules25173788
- By:
- Publication type:
- Article
47
Search for ABCB1 Modulators Among 2-Amine-5-Arylideneimidazolones as a New Perspective to Overcome Cancer Multidrug Resistance.
- Published in:
- Molecules, 2020, v. 25, n. 9, p. 2258, doi. 10.3390/molecules25092258
- By:
- Publication type:
- Article
48
Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro.
- Published in:
- Molecules, 2019, v. 24, n. 24, p. 4472, doi. 10.3390/molecules24244472
- By:
- Publication type:
- Article
49
5-Arylideneimidazolones with Amine at Position 3 as Potential Antibiotic Adjuvants against Multidrug Resistant Bacteria.
- Published in:
- Molecules, 2019, v. 24, n. 3, p. 438, doi. 10.3390/molecules24030438
- By:
- Publication type:
- Article
50
Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT6 Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo.
- Published in:
- Molecules, 2018, v. 23, n. 10, p. 2529, doi. 10.3390/molecules23102529
- By:
- Publication type:
- Article