Works by Lashuel, Hilal A.


Results: 105
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    A user's guide for α-synuclein biomarker studies in biological fluids: Perianalytical considerations.

    Published in:
    2017
    By:
    • Mollenhauer, Brit;
    • Batrla, Richard;
    • El‐Agnaf, Omar;
    • Galasko, Douglas R.;
    • Lashuel, Hilal A.;
    • Merchant, Kalpana M.;
    • Shaw, Lesley M.;
    • Selkoe, Dennis J.;
    • Umek, Robert;
    • Vanderstichele, Hugo;
    • Zetterberg, Henrik;
    • Zhang, Jing;
    • Caspell‐Garcia, Chelsea;
    • Coffey, Chris;
    • Hutten, Samantha J.;
    • Frasier, Mark;
    • Taylor, Peggy;
    • El-Agnaf, Omar;
    • Caspell-Garcia, Chelsea;
    • Investigating Synuclein Consortium of the Michael J. Fox Foundation for Parkinson's Research
    Publication type:
    journal article
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    Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.

    Published in:
    Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97334-z
    By:
    • Herrmann, Frank;
    • Hessmann, Manuela;
    • Schaertl, Sabine;
    • Berg-Rosseburg, Karola;
    • Brown, Christopher J;
    • Bursow, Galina;
    • Chiki, Anass;
    • Ebneth, Andreas;
    • Gehrmann, Miriam;
    • Hoeschen, Nicole;
    • Hotze, Madlen;
    • Jahn, Stefanie;
    • Johnson, Peter D;
    • Khetarpal, Vinod;
    • Kiselyov, Alex;
    • Kottig, Karsten;
    • Ladewig, Stefanie;
    • Lashuel, Hilal;
    • Letschert, Sven;
    • Mills, Matthew R
    Publication type:
    Article
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    Parkin Deficiency Delays Motor Decline and Disease Manifestation in a Mouse Model of Synucleinopathy.

    Published in:
    PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006629
    By:
    • Fournier, Margot;
    • Vitte, Jérémie;
    • Garrigue, Jérôme;
    • Langui, Dominique;
    • Dullin, Jean-Philippe;
    • Saurini, Françoise;
    • Hanoun, Naïma;
    • Perez-Diaz, Fernando;
    • Cornilleau, Fabien;
    • Joubert, Chantal;
    • Ardila-Osorio, Héctor;
    • Traver, Sabine;
    • Duchateau, René;
    • Goujet-Zalc, Cécile;
    • Paleologou, Katerina;
    • Lashuel, Hilal A.;
    • Haass, Christian;
    • Duyckaerts, Charles;
    • Cohen-Salmon, Charles;
    • Kahle, Philipp J.
    Publication type:
    Article
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    TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.

    Published in:
    EMBO Journal, 2020, v. 39, n. 17, p. 1, doi. 10.15252/embj.2020104671
    By:
    • Hegde, Ramanath Narayana;
    • Chiki, Anass;
    • Petricca, Lara;
    • Martufi, Paola;
    • Arbez, Nicolas;
    • Mouchiroud, Laurent;
    • Auwerx, Johan;
    • Landles, Christian;
    • Bates, Gillian P;
    • Singh‐Bains, Malvindar K;
    • Dragunow, Mike;
    • Curtis, Maurice A;
    • Faull, Richard LM;
    • Ross, Christopher A;
    • Caricasole, Andrea;
    • Lashuel, Hilal A
    Publication type:
    Article
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    Membrane scission driven by the PROPPIN Atg18.

    Published in:
    EMBO Journal, 2017, v. 36, n. 22, p. 3274, doi. 10.15252/embj.201796859
    By:
    • Gopaldass, Navin;
    • Fauvet, Bruno;
    • Lashuel, Hilal;
    • Roux, Aurélien;
    • Mayer, Andreas
    Publication type:
    Article
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    c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease.

    Published in:
    Human Molecular Genetics, 2014, v. 23, n. 11, p. 2858, doi. 10.1093/hmg/ddt674
    By:
    • Mahul-Mellier, Anne-Laure;
    • Fauvet, Bruno;
    • Gysbers, Amanda;
    • Dikiy, Igor;
    • Oueslati, Abid;
    • Georgeon, Sandrine;
    • Lamontanara, Allan J.;
    • Bisquertt, Alejandro;
    • Eliezer, David;
    • Masliah, Eliezer;
    • Halliday, Glenda;
    • Hantschel, Oliver;
    • Lashuel, Hilal A.
    Publication type:
    Article
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    Multi‐Targeting Macrocyclic Peptides as Nanomolar Inhibitors of Self‐ and Cross‐Seeded Amyloid Self‐Assembly of α‐Synuclein.

    Published in:
    Angewandte Chemie International Edition, 2025, v. 64, n. 14, p. 1, doi. 10.1002/anie.202422834
    By:
    • Hornung, Simon;
    • Vogl, Dominik P.;
    • Naltsas, Denise;
    • Volta, Beatrice Dalla;
    • Ballmann, Markus;
    • Marcon, Beatrice;
    • Syed, Muhammed Muazzam Kamil;
    • Wu, Yiyang;
    • Spanopoulou, Anna;
    • Feederle, Regina;
    • Heidrich, Luzia;
    • Bernhagen, Jürgen;
    • Koeglsperger, Thomas;
    • Höglinger, Günter U.;
    • Rammes, Gerhard;
    • Lashuel, Hilal A.;
    • Kapurniotu, Aphrodite
    Publication type:
    Article
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    Interactions among α-synuclein, dopamine, and biomembranes.

    Published in:
    Journal of Molecular Neuroscience, 2004, v. 23, n. 1/2, p. 23, doi. 10.1385/JMN:23:1-2:023
    By:
    • Rochet, Jean-Christophe;
    • Fleming Outeiro, Tiago;
    • Conway, Kelly;
    • Ding, Tomas;
    • Volles, Michael;
    • Lashuel, Hilal;
    • Bieganski, Robert;
    • Lindquist, Susan;
    • Lansbury, Peter
    Publication type:
    Article
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    Multi‐Targeting Makrozyklische Peptide als Nanomolare Inhibitoren der Selbst‐ und Kreuznukleation der Amyloiden Selbstassemblierung von α‐Synuclein.

    Published in:
    Angewandte Chemie, 2025, v. 137, n. 14, p. 1, doi. 10.1002/ange.202422834
    By:
    • Hornung, Simon;
    • Vogl, Dominik P.;
    • Naltsas, Denise;
    • Volta, Beatrice Dalla;
    • Ballmann, Markus;
    • Marcon, Beatrice;
    • Syed, Muhammed Muazzam Kamil;
    • Wu, Yiyang;
    • Spanopoulou, Anna;
    • Feederle, Regina;
    • Heidrich, Luzia;
    • Bernhagen, Jürgen;
    • Koeglsperger, Thomas;
    • Höglinger, Günter U.;
    • Rammes, Gerhard;
    • Lashuel, Hilal A.;
    • Kapurniotu, Aphrodite
    Publication type:
    Article
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