Works by Larrea, Delfina

Results: 10

Aberrant ER-mitochondria communication is a common pathomechanism in mitochondrial disease.
Published in:
Cell Death & Disease, 2024, v. 15, n. 6, p. 1, doi. 10.1038/s41419-024-06781-9
By:
- Morcillo, Patricia;
- Kabra, Khushbu;
- Velasco, Kevin;
- Cordero, Hector;
- Jennings, Sarah;
- Yun, Taekyung D.;
- Larrea, Delfina;
- Akman, H. Orhan;
- Schon, Eric A.
Publication type:
Article
APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61142-8
By:
- Area-Gomez, Estela;
- Larrea, Delfina;
- Pera, Marta;
- Agrawal, Rishi R.;
- Guilfoyle, David N.;
- Pirhaji, Leila;
- Shannon, Kathleen;
- Arain, Hirra A.;
- Ashok, Archana;
- Chen, Qiuying;
- Dillman, Allissa A.;
- Figueroa, Helen Y.;
- Cookson, Mark R.;
- Gross, Steven S.;
- Fraenkel, Ernest;
- Duff, Karen E.;
- Nuriel, Tal
Publication type:
Article
Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS).
Published in:
Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-024-51578-1
By:
- Larrea, Delfina;
- Tamucci, Kirstin A.;
- Kabra, Khushbu;
- Velasco, Kevin R.;
- Yun, Taekyung D.;
- Pera, Marta;
- Montesinos, Jorge;
- Agrawal, Rishi R.;
- Paradas, Carmen;
- Smerdon, John W.;
- Lowry, Emily R.;
- Stepanova, Anna;
- Yoval-Sanchez, Belem;
- Galkin, Alexander;
- Wichterle, Hynek;
- Area-Gomez, Estela
Publication type:
Article
Alzheimer's-Associated Upregulation of Mitochondria-Associated ER Membranes After Traumatic Brain Injury.
Published in:
Cellular & Molecular Neurobiology, 2023, v. 43, n. 5, p. 2219, doi. 10.1007/s10571-022-01299-0
By:
- Agrawal, Rishi R.;
- Larrea, Delfina;
- Xu, Yimeng;
- Shi, Lingyan;
- Zirpoli, Hylde;
- Cummins, Leslie G.;
- Emmanuele, Valentina;
- Song, Donghui;
- Yun, Taekyung D.;
- Macaluso, Frank P.;
- Min, Wei;
- Kernie, Steven G.;
- Deckelbaum, Richard J.;
- Area-Gomez, Estela
Publication type:
Article
Substrate translocation involves specific lysine residues of the central channel of the conjugative coupling protein TrwB.
Published in:
Molecular Genetics & Genomics, 2017, v. 292, n. 5, p. 1037, doi. 10.1007/s00438-017-1331-3
By:
- Larrea, Delfina;
- Paz, Héctor;
- Matilla, Inmaculada;
- Guzmán-Herrador, Dolores;
- Lasso, Gorka;
- Cruz, Fernando;
- Cabezón, Elena;
- Llosa, Matxalen
Publication type:
Article
The Alzheimer's disease‐associated C99 fragment of APP regulates cellular cholesterol trafficking.
Published in:
EMBO Journal, 2020, v. 39, n. 20, p. 1, doi. 10.15252/embj.2019103791
By:
- Montesinos, Jorge;
- Pera, Marta;
- Larrea, Delfina;
- Guardia‐Laguarta, Cristina;
- Agrawal, Rishi R;
- Velasco, Kevin R;
- Yun, Taekyung D;
- Stavrovskaya, Irina G;
- Xu, Yimeng;
- Koo, So Yeon;
- Snead, Amanda M;
- Sproul, Andrew A;
- Area‐Gomez, Estela
Publication type:
Article
Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease.
Published in:
EMBO Journal, 2017, v. 36, n. 22, p. 3356, doi. 10.15252/embj.201796797
By:
- Pera, Marta;
- Larrea, Delfina;
- Guardia‐Laguarta, Cristina;
- Montesinos, Jorge;
- Velasco, Kevin R;
- Agrawal, Rishi R;
- Xu, Yimeng;
- Chan, Robin B;
- Di Paolo, Gilbert;
- Mehler, Mark F;
- Perumal, Geoffrey S;
- Macaluso, Frank P;
- Freyberg, Zachary Z;
- Acin‐Perez, Rebeca;
- Enriquez, Jose Antonio;
- Schon, Eric A;
- Area‐Gomez, Estela
Publication type:
Article
PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects.
Published in:
2018
By:
- Kraakman, Michael J.;
- Qiongming Liu;
- Postigo-Fernandez, Jorge;
- Ruiping Ji;
- Ning Kon;
- Larrea, Delfina;
- Namwanje, Maria;
- Lihong Fan;
- Chan, Michelle;
- Area-Gomez, Estela;
- Wenxian Fu;
- Creusot, Remi J.;
- Li Qiang;
- J Kraakman, Michael;
- Liu, Qiongming;
- Ji, Ruiping;
- Kon, Ning;
- Fan, Lihong;
- Fu, Wenxian;
- J Creusot, Remi
Publication type:
journal article
MFN2 mutations in Charcot–Marie–Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics.
Published in:
Human Molecular Genetics, 2019, v. 28, n. 11, p. 1782, doi. 10.1093/hmg/ddz008
By:
- Larrea, Delfina;
- Pera, Marta;
- Gonnelli, Adriano;
- Quintana–Cabrera, Rubén;
- Akman, H Orhan;
- Guardia-Laguarta, Cristina;
- Velasco, Kevin R;
- Area-Gomez, Estela;
- Bello, Federica Dal;
- Stefani, Diego De;
- Horvath, Rita;
- Shy, Michael E;
- Schon, Eric A;
- Giacomello, Marta
Publication type:
Article
The C99 fragment of APP regulates cholesterol trafficking: Molecular and cell biology/APP/Abeta/amyloid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038479
By:
- Montesinos, Jorge;
- Pera, Marta;
- Larrea, Delfina;
- Guardia‐Laguarta, Cristina;
- Area‐Gomez, Estela
Publication type:
Article