Works by Lanza, Ian R

Results: 56

Aerobic and resistance exercise-regulated phosphoproteome and acetylproteome modifications in human skeletal muscle.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60049-0

By:

Pataky, Mark W.;
Heppelmann, Carrie J.;
Sevits, Kyle J.;
Asokan, Aneesh K.;
Kumar, Arathi Prabha;
Klaus, Katherine A.;
Dasari, Surendra;
Kunz, Hawley E.;
Strub, Matthew D.;
Robinson, Matthew M.;
Coon, Joshua J.;
Lanza, Ian R.;
Adams, Christopher M.;
Nair, K. Sreekumaran

Publication type:

Article

Extramyocellular interleukin‐6 influences skeletal muscle mitochondrial physiology through canonical JAK/STAT signaling pathways.

Published in:

FASEB Journal, 2020, v. 34, n. 11, p. 14458, doi. 10.1096/fj.202000965RR

By:

Abid, Hinnah;
Ryan, Zachary C.;
Delmotte, Philippe;
Sieck, Gary C.;
Lanza, Ian R.

Publication type:

Article

Impaired cardiac performance, protein synthesis, and mitochondrial function in tumor-bearing mice.

Published in:

PLoS ONE, 2019, v. 14, n. 12, p. 1, doi. 10.1371/journal.pone.0226440

By:

Berent, Taylor E.;
Dorschner, Jessica M.;
Meyer, Thomas;
Craig, Theodore A.;
Wang, Xuewei;
Kunz, Hawley;
Jatoi, Aminah;
Lanza, Ian R.;
Chen, Horng;
Kumar, Rajiv

Publication type:

Article

Effects of Dietary n-3 Fatty Acids on Hepatic and Peripheral Insulin Sensitivity in Insulin-Resistant Humans.

Published in:

Diabetes Care, 2015, v. 38, n. 7, p. 1228, doi. 10.2337/dc14-3101

By:

Lalia, Antigoni Z.;
Johnson, Matthew L.;
Jensen, Michael D.;
Hames, Kazanna C.;
Port, John D.;
Lanza, Ian R.

Publication type:

Article

Impact of obesity on the molecular response to a single bout of exercise in a preliminary human cohort.

Published in:

2022

By:

Vanderboom, Patrick;
Zhang, Xiaoyan;
Hart, Corey R.;
Kunz, Hawley E.;
Gries, Kevin J.;
Heppelmann, Carrie J.;
Liu, Yuanhang;
Dasari, Surendra;
Lanza, Ian R.

Publication type:

journal article

Association of UCP-3 rs1626521 with obesity and stomach functions in humans.

Published in:

Obesity (19307381), 2015, v. 23, n. 4, p. 898, doi. 10.1002/oby.21039

By:

Acosta, Andres;
Camilleri, Michael;
Shin, Andrea;
Vazquez‐Roque, Maria I.;
Iturrino, Johanna;
Lanza, Ian R.;
Nair, K. Sreekumaran;
Burton, Duane;
O'Neill, Jessica;
Eckert, Deborah;
Carlson, Paula;
Vella, Adrian;
Zinsmeister, Alan R.

Publication type:

Article

NLRP3 Inflammasome Activation and Altered Mitophagy Are Key Pathways in Inclusion Body Myositis.

Published in:

Journal of Cachexia, Sarcopenia & Muscle, 2025, v. 16, n. 1, p. 1, doi. 10.1002/jcsm.13672

By:

Naddaf, Elie;
Nguyen, Thi Kim Oanh;
Watzlawik, Jens O.;
Gao, Huanyao;
Hou, Xu;
Fiesel, Fabienne C.;
Mandrekar, Jay;
Kokesh, Eileen;
Harmsen, William S.;
Lanza, Ian R.;
Springer, Wolfdieter;
Trushina, Eugenia

Publication type:

Article

Noninvasive Monitoring of the Mitochondrial Function in Mesenchymal Stromal Cells.

Published in:

2016

By:

Franchi, Federico;
Peterson, Karen;
Paulmurugan, Ramasamy;
Folmes, Clifford;
Lanza, Ian;
Lerman, Amir;
Rodriguez-Porcel, Martin;
Peterson, Karen M;
Lanza, Ian R

Publication type:

journal article

Effects of old age on human skeletal muscle energetics during fatiguing contractions with and without blood flow.

Published in:

Journal of Physiology, 2007, v. 583, n. 3, p. 1093, doi. 10.1113/jphysiol.2007.138362

By:

Lanza, Ian R.;
Larsen, Ryan G.;
Kent-Braun, Jane A.

Publication type:

Article

In vivo ATP production during free-flow and ischaemic muscle contractions in humans.

Published in:

Journal of Physiology, 2006, v. 577, n. 1, p. 353, doi. 10.1113/jphysiol.2006.114249

By:

Lanza, Ian R.;
Wigmore, Danielle M.;
Befroy, Douglas E.;
Kent-Braun, Jane A.

Publication type:

Article

A comprehensive protocol for multiplatform metabolomics analysis in patient-derived skin fibroblasts.

Published in:

Metabolomics, 2019, v. 15, n. 6, p. N.PAG, doi. 10.1007/s11306-019-1544-z

By:

Wilkins, Jordan;
Sakrikar, Dhananjay;
Petterson, Xuan-Mai;
Lanza, Ian R.;
Trushina, Eugenia

Publication type:

Article

312 Metabolomics Approach to Cellular Senescence: Characterizing the Secretory Phenotype and Metabolism of Irradiation-Induced Senescent Human Pre- Adipocytes.

Published in:

2023

By:

Ortiz-Correa, Zinnarky Kiani;
Lanza, Ian R.

Publication type:

Abstract

Predictors of Whole-Body Insulin Sensitivity Across Ages and Adiposity in Adult Humans.

Published in:

2016

By:

Lalia, Antigoni Z;
Dasari, Surendra;
Johnson, Matthew L;
Robinson, Matthew M;
Konopka, Adam R;
Distelmaier, Klaus;
Port, John D;
Glavin, Maria T;
Esponda, Raul Ruiz;
Nair, K Sreekumaran;
Lanza, Ian R

Publication type:

journal article

Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age.

Published in:

2015

By:

Irving, Brian A;
Lanza, Ian R;
Henderson, Gregory C;
Rao, Rajesh R;
Spiegelman, Bruce M;
Nair, K Sreekumaran

Publication type:

journal article

Adipocyte mitochondrial function is reduced in human obesity independent of fat cell size.

Published in:

2014

By:

Yin, Xiao;
Lanza, Ian R;
Swain, James M;
Sarr, Michael G;
Nair, K Sreekumaran;
Jensen, Michael D

Publication type:

journal article

Mitochondrial function as a determinant of life span.

Published in:

Pflügers Archiv: European Journal of Physiology, 2010, v. 459, n. 2, p. 277, doi. 10.1007/s00424-009-0724-5

By:

Lanza, Ian R.;
Nair, K. Sreekumaran

Publication type:

Article

Human myofiber‐enriched aging‐induced lncRNAFRAIL1 promotes loss of skeletal muscle function.

Published in:

Aging Cell, 2024, v. 23, n. 4, p. 1, doi. 10.1111/acel.14097

By:

Miller, Matthew J.;
Gries, Kevin J.;
Marcotte, George R.;
Ryan, Zachary;
Strub, Matthew D.;
Kunz, Hawley E.;
Arendt, Bonnie K.;
Dasari, Surendra;
Ebert, Scott M.;
Adams, Christopher M.;
Lanza, Ian R.

Publication type:

Article

Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice.

Published in:

Aging Cell, 2015, v. 14, n. 5, p. 734, doi. 10.1111/acel.12352

By:

Johnson, Matthew L.;
Lalia, Antigoni Z.;
Dasari, Surendra;
Pallauf, Maximilian;
Fitch, Mark;
Hellerstein, Marc K.;
Lanza, Ian R.

Publication type:

Article

Preserved skeletal muscle oxidative capacity in older adults despite decreased cardiorespiratory fitness with ageing.

Published in:

Journal of Physiology, 2021, v. 599, n. 14, p. 3581, doi. 10.1113/JP281691

By:

Zhang, Xiaoyan;
Kunz, Hawley E.;
Gries, Kevin;
Hart, Corey R.;
Polley, Eric C.;
Lanza, Ian R.

Publication type:

Article

A Randomized Trial of the Effects of Dietary n3-PUFAs on Skeletal Muscle Function and Acute Exercise Response in Healthy Older Adults.

Published in:

Nutrients, 2022, v. 14, n. 17, p. 3537, doi. 10.3390/nu14173537

By:

Kunz, Hawley E.;
Michie, Kelly L.;
Gries, Kevin J.;
Zhang, Xiaoyan;
Ryan, Zachary C.;
Lanza, Ian R.

Publication type:

Article

Insulin-Sensitizing Effects of Omega-3 Fatty Acids: Lost in Translation?

Published in:

Nutrients, 2016, v. 8, n. 6, p. 329, doi. 10.3390/nu8060329

By:

Lalia, Antigoni Z.;
Lanza, Ian R.

Publication type:

Article

A Fresh Look at Fuel Selection in Working Muscle.

Published in:

2023

By:

Kunz, Hawley E.;
Lanza, Ian R.

Publication type:

Editorial

Metabolomic response to acute resistance exercise in healthy older adults by 1H-NMR.

Published in:

PLoS ONE, 2024, v. 19, n. 3, p. 1, doi. 10.1371/journal.pone.0301037

By:

Moosavi, Darya;
Vuckovic, Ivan;
Kunz, Hawley E.;
Lanza, Ian R.

Publication type:

Article

Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes.

Published in:

FASEB Journal, 2019, v. 33, n. 3, p. 4458, doi. 10.1096/fj.201802043R

By:

Ruegsegger, Gregory N.;
Manjunatha, Shankarappa;
Summer, Priska;
Gopala, Srinivas;
Zabeilski, Piotr;
Dasari, Surendra;
Vanderboom, Patrick M.;
Lanza, Ian R.;
Klaus, Katherine A.;
Nair, K. Sreekumaran

Publication type:

Article

Influence of Fish Oil on Skeletal Muscle Mitochondrial Energetics and Lipid Metabolites during High‐Fat Diet.

Published in:

FASEB Journal, 2013, v. 27, p. 1154.8, doi. 10.1096/fasebj.27.1_supplement.1154.8

By:

Lanza, Ian R.;
Blachnio‐Zabielska, Agnieszka;
Zabielski, Piotrek;
Nair, K. Sreekumaran;
Jensen, Michael;
Lebrasseur, Nathan

Publication type:

Article

Altered Skeletal Muscle Mitochondrial Proteome As the Basis of Disruption of Mitochondrial Function in Diabetic Mice.

Published in:

2016

By:

Zabielski, Piotr;
Lanza, Ian R.;
Gopala, Srinivas;
Heppelmann, Carrie J. Holtz;
Bergen III, H. Robert;
Dasari, Surendra;
Sreekumaran Nair, K.;
Holtz Heppelmann, Carrie J;
Bergen, H Robert 3rd;
Nair, K Sreekumaran

Publication type:

journal article

Mechanism by Which Caloric Restriction Improves Insulin Sensitivity in Sedentary Obese Adults.

Published in:

2016

By:

Johnson, Matthew L.;
Distelmaier, Klaus;
Lanza, Ian R.;
Irving, Brian A.;
Robinson, Matthew M.;
Konopka, Adam R.;
Shulman, Gerald I.;
Nair, K. Sreekumaran

Publication type:

journal article

Enhancing the Metabolic Benefits of Bariatric Surgery: Tipping the Scales With Exercise.

Published in:

2015

By:

Lanza, Ian R.

Publication type:

journal article

Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training.

Published in:

2015

By:

Konopka, Adam R;
Asante, Albert;
Lanza, Ian R;
Robinson, Matthew M;
Johnson, Matthew L;
Dalla Man, Chiara;
Cobelli, Claudio;
Amols, Mark H;
Irving, Brian A;
Nair, K S

Publication type:

journal article

Defects inMitochondrial Efficiency and H2O2 Emissions in Obese Women Are Restored to a Lean Phenotype With Aerobic Exercise Training.

Published in:

Diabetes, 2015, v. 64, n. 6, p. 2104, doi. 10.2337/db14-1701

By:

Konopka, Adam R.;
Asante, Albert;
Lanza, Ian R.;
Robinson, Matthew M.;
Johnson, Matthew L.;
Man, Chiara Dalla;
Cobelli, Claudio;
Amols, Mark H.;
Irving, Brian A.;
Nair, K. S.

Publication type:

Article

Methods for Assessing Mitochondrial Function in Diabetes.

Published in:

Diabetes, 2013, v. 62, n. 4, p. 1041, doi. 10.2337/db12-1219

By:

Perry, Christopher G. R.;
Kane, Daniel A.;
Lanza, Ian R.;
Neufer, P. Darrell

Publication type:

Article

Endurance Exercise as a Countermeasure for Aging.

Published in:

Diabetes, 2008, v. 57, n. 11, p. 2933, doi. 10.2337/db08-0349

By:

Lanza, Ian R.;
Short, Daniel K.;
Short, Kevin R.;
Raghavakaimal, Sreekumar;
Basu, Rita;
Joyner, Michael J.;
McConnell, Joseph P.;
Nair, K. Sreekumaran

Publication type:

Article

Measurement of human skeletal muscle oxidative capacity by 31P-MR spectroscopy: a cross-validation with in vitro measurements.

Published in:

2011

By:

Lanza IR;
Bhagra S;
Nair KS;
Port JD;
Lanza, Ian R;
Bhagra, Sumit;
Nair, K Sreekumaran;
Port, John D

Publication type:

journal article

Measurement of human skeletal muscle oxidative capacity by 31P-MR spectroscopy: A cross-validation with in vitro measurements.

Published in:

Journal of Magnetic Resonance Imaging, 2011, v. 34, n. 5, p. 1143, doi. 10.1002/jmri.22733

By:

Lanza, Ian R.;
Bhagra, Sumit;
Nair, K. Sreekumaran;
Port, John D.

Publication type:

Article

Rebuttal: reduced oxidative capacity of skeletal muscle IS NOT an inevitable consequence of adult ageing.

Published in:

Journal of Physiology, 2025, v. 603, n. 1, p. 27, doi. 10.1113/JP286695

By:

Lanza, Ian R.;
Sundberg, Christopher W.;
Kent, Jane A.

Publication type:

Article

Reduced oxidative capacity of skeletal muscle IS NOT an inevitable consequence of adult ageing.

Published in:

Journal of Physiology, 2025, v. 603, n. 1, p. 21, doi. 10.1113/JP285042

By:

Lanza, Ian R.;
Sundberg, Christopher W.;
Kent, Jane A.

Publication type:

Article

Cystathionine Beta-Synthase (CBS) Contributes to Advanced Ovarian Cancer Progression and Drug Resistance.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079167

By:

Bhattacharyya, Sanjib;
Saha, Sounik;
Giri, Karuna;
Lanza, Ian R.;
Nair, K. Sreekumar;
Jennings, Nicholas B.;
Rodriguez-Aguayo, Cristian;
Lopez-Berestein, Gabriel;
Basal, Eati;
Weaver, Amy L.;
Visscher, Daniel W.;
Cliby, William;
Sood, Anil K.;
Bhattacharya, Resham;
Mukherjee, Priyabrata

Publication type:

Article

Quantitative Metabolomics by 1H-NMR and LC-MS/MS Confirms Altered Metabolic Pathways in Diabetes.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010538

By:

Lanza, Ian R.;
Shucha Zhang;
Ward, Lawrence E.;
Karakelides, Helen;
Raftery, Daniel;
Sreekumaran Nair, K.

Publication type:

Article

Contraction frequency modulates muscle fatigue and the rate of myoglobin desaturation during incremental contractions in humans.

Published in:

Applied Physiology, Nutrition & Metabolism, 2008, v. 33, n. 5, p. 915, doi. 10.1139/H08-085

By:

Wigmore, Danielle M.;
Befroy, Douglas E.;
Lanza, Ian R.;
Kent-Braun, Jane A.

Publication type:

Article

Intramyocellular oxygenation during ischemic muscle contractions in vivo.

Published in:

2009

By:

Tevald, Michael A.;
Lanza, Ian R.;
Befroy, Douglas E.;
Kent-Braun, Jane A.

Publication type:

journal article

Metabo‐ and mechanoreceptor expression in human heart failure: Relationships with the locomotor muscle afferent influence on exercise responses.

Published in:

Experimental Physiology, 2020, v. 105, n. 5, p. 809, doi. 10.1113/EP088353

By:

Smith, Joshua R.;
Hart, Corey R.;
Ramos, Paola A.;
Akinsanya, Joshua G.;
Lanza, Ian R.;
Joyner, Michael J.;
Curry, Timothy B.;
Olson, Thomas P.

Publication type:

Article

Acute responsiveness to single leg cycling in adults with obesity.

Published in:

Physiological Reports, 2022, v. 10, n. 24, p. 1, doi. 10.14814/phy2.15539

By:

Gries, Kevin J.;
Hart, Corey R.;
Kunz, Hawley E.;
Ryan, Zachary;
Zhang, Xiaoyan;
Parvizi, Mojtaba;
Liu, Yuanhang;
Dasari, Surendra;
Lanza, Ian R.

Publication type:

Article

Chronically endurance-trained individuals preserve skeletal muscle mitochondrial gene expression with age but differences within age groups remain.

Published in:

Physiological Reports, 2014, v. 2, n. 12, p. n/a, doi. 10.14814/phy2.12239

By:

Johnson, Matthew L.;
Lanza, Ian R.;
Short, Daniel K.;
Asmann, Yan W.;
Nair, K. Sreekumaran

Publication type:

Article

Insulin Regulation of Lysine and α-Aminoadipic Acid Dynamics and Amino Metabolites in Women With and Without Insulin Resistance.

Published in:

Diabetes, 2024, v. 73, n. 10, p. 1592, doi. 10.2337/db23-0977

By:

Chang, Alice Y.;
Asokan, Aneesh K.;
Lalia, Antigoni Z.;
Sakrikar, Dhananjay;
Lanza, Ian R.;
Petterson, Xuan-Mai;
Nair, K. Sreekumaran

Publication type:

Article

The Effect of Glucagon on Protein Catabolism During Insulin Deficiency: Exchange of Amino Acids Across Skeletal Muscle and the Splanchnic Bed.

Published in:

2022

By:

James, Haleigh;
Gonsalves, Wilson I.;
Manjunatha, Shankarappa;
Dasari, Surendra;
Lanza, Ian R.;
Klaus, Katherine A.;
Vella, Adrian;
Andrews, James C.;
Nair, K. Sreekumaran

Publication type:

journal article

500-P: Determinants of Exercise-Induced Increase in Insulin Sensitivity.

Published in:

Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-500-P

By:

KUMAR, ARATHI PRABHA;
DASARI, SURENDRA;
PATAKY, MARK W.;
CROOK, JULIA;
BALL, COLLEEN T.;
KLAUS, KATHERINE;
LANZA, IAN R.;
ROBINSON, MATTHEW M.;
NAIR, K. SREEKUMARAN

Publication type:

Article

Erratum. TFAM Enhances Fat Oxidation and Attenuates High-Fat Diet-Induced Insulin Resistance in Skeletal Muscle. Diabetes 2019;68:1552-1564.

Published in:

2020

By:

Koh, Jin-Ho;
Johnson, Matthew L.;
Dasari, Surendra;
LeBrasseur, Nathan K.;
Vuckovic, Ivan;
Henderson, Gregory C.;
Cooper, Shawna A.;
Manjunatha, Shankarappa;
Ruegsegger, Gregory N.;
Shulman, Gerald I.;
Lanza, Ian R.;
Nair, K. Sreekumaran

Publication type:

journal article

2121-P: Proinflammatory Cytokines Alter Beta-Cell Exosome Cargo and Function to Enhance Activation of the CXCL10-CXCR3 Axis in Diabetes.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2121-P

By:

JAVEED, NAUREEN;
HER, TRACY K.;
BROWN, MATTHEW;
VANDERBOOM, PATRICK M.;
EGAN, AOIFE M.;
VELLA, ADRIAN;
LANZA, IAN R.;
PATEL, TUSHAR;
MATVEYENKO, ALEKSEY

Publication type:

Article

TFAM Enhances Fat Oxidation and Attenuates High-Fat Diet-Induced Insulin Resistance in Skeletal Muscle.

Published in:

2019

By:

Jin-Ho Koh;
Johnson, Matthew L.;
Dasari, Surendra;
LeBrasseur, Nathan K.;
Vuckovic, Ivan;
Henderson, Gregory C.;
Cooper, Shawna A.;
Manjunatha, Shankarappa;
Ruegsegger, Gregory N.;
Shulman, Gerald I.;
Lanza, Ian R.;
Nair, K. Sreekumaran;
Koh, Jin-Ho

Publication type:

journal article

2192-P: Extracellular Vesicles as Novel Mediators of Proinflammatory Cytokine-Induced ß-Cell Dysfunction.

Published in:

Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2192-P

By:

JAVEED, NAUREEN;
HER, TRACY K.;
VANDERBOOM, PATRICK M.;
LANZA, IAN R.;
MATVEYENKO, ALEKSEY

Publication type:

Article