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Amyloid-beta antibody binding to cerebral amyloid angiopathy fibrils and risk for amyloid-related imaging abnormalities.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-61691-2
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- Publication type:
- Article
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion.
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- Acta Neuropathologica Communications, 2024, v. 12, p. 1, doi. 10.1186/s40478-024-01734-x
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- Publication type:
- Article
The interwoven fibril-like structure of amyloid-beta plaques in mouse brain tissue visualized using super-resolution STED microscopy.
- Published in:
- Cell & Bioscience, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13578-023-01086-4
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- Publication type:
- Article
Correction: A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Correction: A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody.
- Published in:
- 2022
- By:
- Publication type:
- Correction Notice
Correction to: A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody.
- Published in:
- 2022
- By:
- Publication type:
- Correction Notice
Mutation analysis of disease causing genes in patients with early onset or familial forms of Alzheimer's disease and frontotemporal dementia.
- Published in:
- BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-08343-9
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- Publication type:
- Article
Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta.
- Published in:
- Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00258-x
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- Publication type:
- Article
Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta.
- Published in:
- Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00258-x
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- Publication type:
- Article
The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.
- Published in:
- Science Translational Medicine, 2021, v. 13, n. 606, p. 1, doi. 10.1126/scitranslmed.abc6184
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- Publication type:
- Article
Heparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: relevance to Alzheimer's disease.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01182-x
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- Publication type:
- Article
A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody.
- Published in:
- Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00813-8
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- Publication type:
- Article
Characterization of monomeric and soluble aggregated Aβ in Down's syndrome and Alzheimer's disease brains: Human neuropathology/amyloid.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042479
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- Publication type:
- Article
P4‐704: BAN2401 SHOWS STRONGER BINDING TO SOLUBLE AGGREGATED AMYLOID‐BETA SPECIES THAN ADUCANUMAB.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1601, doi. 10.1016/j.jalz.2019.09.068
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- Publication type:
- Article
Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain.
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- Science Translational Medicine, 2019, v. 11, n. 490, p. N.PAG, doi. 10.1126/scitranslmed.aat8462
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- Publication type:
- Article
Antibody-Based In Vivo PET Imaging Detects Amyloid-β Reduction in Alzheimer Transgenic Mice After BACE-1 Inhibition.
- Published in:
- Journal of Nuclear Medicine, 2018, v. 59, n. 12, p. 1885, doi. 10.2967/jnumed.118.213140
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- Publication type:
- Article
DT‐01‐07: TREATMENT OF EARLY AD SUBJECTS WITH BAN2401, AN ANTI‐Aβ PROTOFIBRIL MONOCLONAL ANTIBODY, SIGNIFICANTLY CLEARS AMYLOID PLAQUE AND REDUCES CLINICAL DECLINE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1668, doi. 10.1016/j.jalz.2018.07.009
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- Publication type:
- Article
P4‐233: AGED ALZHEIMER'S DISEASE BRAINS EXHIBIT NUMEROUS Aβ BUT ONLY FEW TAU PRIONS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1531, doi. 10.1016/j.jalz.2018.07.054
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- Publication type:
- Article
Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers.
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- Acta Neuropathologica, 2018, v. 136, n. 1, p. 41, doi. 10.1007/s00401-018-1868-1
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- Publication type:
- Article
Rapid amyloid‐β oligomer and protofibril accumulation in traumatic brain injury.
- Published in:
- Brain Pathology, 2018, v. 28, n. 4, p. 451, doi. 10.1111/bpa.12532
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- Publication type:
- Article
Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.
- Published in:
- Alzheimer's Research & Therapy, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13195-018-0377-8
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- Publication type:
- Article
The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death.
- Published in:
- 2018
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- Publication type:
- journal article
Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes.
- Published in:
- 2017
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- Publication type:
- journal article
Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein.
- Published in:
- Cellular & Molecular Neurobiology, 2017, v. 37, n. 7, p. 1217, doi. 10.1007/s10571-016-0454-0
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- Publication type:
- Article
Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells.
- Published in:
- Biological Procedures Online, 2017, v. 19, p. 1, doi. 10.1186/s12575-017-0060-7
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- Publication type:
- Article
PHARMACOLOGICAL CHARACTERIZATION OF BAN2401-MEDIATED Aβ PROTOFIBRIL CLEARANCE BY MICROGLIA.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P625, doi. 10.1016/j.jalz.2017.06.704
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- Publication type:
- Article
GENOTYPE-DEPENDENT LONGITUDINAL TRAJECTORIES OF COGNITIVE DECLINE IN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1554, doi. 10.1016/j.jalz.2017.07.695
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- Publication type:
- Article
Predicting Cognitive Decline across Four Decades in Mutation Carriers and Non-carriers in Autosomal-Dominant Alzheimer’s Disease.
- Published in:
- Journal of the International Neuropsychological Society, 2017, v. 23, n. 3, p. 195, doi. 10.1017/S1355617716001028
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- Publication type:
- Article
Decreased HHV-6 IgG in Alzheimer's Disease.
- Published in:
- Frontiers in Neurology, 2017, v. 8, p. 1, doi. 10.3389/fneur.2017.00040
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- Publication type:
- Article
Cellular Uptake of α-Synuclein Oligomer-Selective Antibodies is Enhanced by the Extracellular Presence of α-Synuclein and Mediated via Fcγ Receptors.
- Published in:
- Cellular & Molecular Neurobiology, 2017, v. 37, n. 1, p. 121, doi. 10.1007/s10571-016-0352-5
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- Publication type:
- Article
CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease.
- Published in:
- Proteomics - Clinical Applications, 2016, v. 10, n. 12, p. 1242, doi. 10.1002/prca.201500150
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- Publication type:
- Article
High tau levels in cerebrospinal fluid predict nursing home placement and rapid progression in Alzheimer's disease.
- Published in:
- Alzheimer's Research & Therapy, 2016, v. 8, p. 1, doi. 10.1186/s13195-016-0191-0
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- Publication type:
- Article
Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons.
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0098-z
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- Publication type:
- Article
Safety and tolerability of BAN2401 - a clinical study in Alzheimer's disease with a protofibril selective Aβ antibody.
- Published in:
- Alzheimer's Research & Therapy, 2016, v. 8, p. 1, doi. 10.1186/s13195-016-0181-2
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- Publication type:
- Article
Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models.
- Published in:
- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0294-7
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- Publication type:
- Article
Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease.
- Published in:
- PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150672
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- Publication type:
- Article
Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease.
- Published in:
- Nature Communications, 2016, v. 7, n. 2, p. 10759, doi. 10.1038/ncomms10759
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- Publication type:
- Article
η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
- Published in:
- Nature, 2015, v. 526, n. 7573, p. 443, doi. 10.1038/nature14864
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- Publication type:
- Article
Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 10, p. 1180, doi. 10.1016/j.jalz.2014.10.009
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- Publication type:
- Article
A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status.
- Published in:
- Genome Biology, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s13059-015-0750-x
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- Publication type:
- Article
Self-reported sleep disturbance is associated with Alzheimer's disease risk in men.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 9, p. 1090, doi. 10.1016/j.jalz.2014.08.104
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- Publication type:
- Article
Micellar extraction possesses a new advantage for the analysis of Alzheimer's disease brain proteome.
- Published in:
- Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 4, p. 1041, doi. 10.1007/s00216-014-8320-8
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- Publication type:
- Article
Consideration for “early Alzheimer's disease (AD)” trials with a single prodromal AD and mild AD dementia population: ADNI data analysis and initial observations from the BAN2401-G000-201 trial.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P778, doi. 10.1016/j.jalz.2014.05.1499
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- Publication type:
- Article
Initial learnings from screening strategies in the BAN 2401-G000-201 trial: An early Alzheimer's disease study.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P855, doi. 10.1016/j.jalz.2014.05.1698
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- Publication type:
- Article
Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer.
- Published in:
- Nature Genetics, 2014, v. 46, n. 6, p. 624, doi. 10.1038/ng.2966
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- Publication type:
- Article
Increased Inflammatory Response in Cytomegalovirus Seropositive Patients with Alzheimer’s Disease.
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096779
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- Publication type:
- Article
Perspectives on future Alzheimer therapies: amyloid-β protofibrils - a new target for immunotherapy with BAN2401 in Alzheimer's disease.
- Published in:
- Alzheimer's Research & Therapy, 2014, v. 6, n. 2, p. 1, doi. 10.1186/alzrt246
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- Publication type:
- Article
Abundance of Aβ<sub>5-x</sub> like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer's disease.
- Published in:
- Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-13
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- Publication type:
- Article
Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging.
- Published in:
- BMC Neuroscience, 2013, v. 14, n. 1, p. 2, doi. 10.1186/1471-2202-14-148
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- Publication type:
- Article
Decreased Proportion of Cytomegalovirus Specific CD8 T-Cells but No Signs of General Immunosenescence in Alzheimer’s Disease.
- Published in:
- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077921
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- Publication type:
- Article