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PET imaging of the mouse brain reveals a dynamic regulation of SERT density in a chronic stress model.
- Published in:
- Translational Psychiatry, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41398-019-0416-7
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- Publication type:
- Article
Characterization of an APP/tau rat model of Alzheimer's disease by positron emission tomography and immunofluorescent labeling.
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- Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00916-2
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- Publication type:
- Article
Liver Imaging and Hepatobiliary Contrast Media.
- Published in:
- Contrast Media & Molecular Imaging, 2018, p. 1, doi. 10.1155/2018/2487405
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- Publication type:
- Article
Reproducibility of Quantitative Brain Imaging Using a PET-Only and a Combined PET/MR System.
- Published in:
- Frontiers in Neuroscience, 2017, p. 1, doi. 10.3389/fnins.2017.00396
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- Publication type:
- Article
A Novel Positron Emission Tomography Imaging Protocol Identifies Seizure-Induced Regional Overactivity of P-Glycoprotein at the Blood-Brain Barrier.
- Published in:
- Journal of Neuroscience, 2011, v. 31, n. 24, p. 8803, doi. 10.1523/JNEUROSCI.6616-10.2011
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- Publication type:
- Article
Pgp-Mediated Interaction Between (R)-[<sup>11</sup>C]Verapamil and Tariquidar at the Human Blood-Brain Barrier: A Comparison With Rat Data.
- Published in:
- Clinical Pharmacology & Therapeutics, 2012, v. 91, n. 2, p. 227, doi. 10.1038/clpt.2011.217
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- Publication type:
- Article
A positron emission tomography microdosing study with a potential antiamyloid drug in healthy volunteers and patients with Alzheimer's disease<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2006, v. 80, n. 3, p. 216, doi. 10.1016/j.clpt.2006.05.007
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- Publication type:
- Article
Influence of functional haplotypes in the drug transporter gene ABCB1 on central nervous system drug distribution in humans
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- Clinical Pharmacology & Therapeutics, 2005, v. 78, n. 2, p. 182, doi. 10.1016/j.clpt.2005.04.011
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- Publication type:
- Article
A Pilot Study to Assess the Efficacy of Tariquidar to Inhibit P-glycoprotein at the Human Blood-Brain Barrier with (R)-<sup>11</sup>C-Verapamil and PET.
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- Journal of Nuclear Medicine, 2009, v. 50, n. 12, p. 1954, doi. 10.2967/jnumed.109.063289
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- Publication type:
- Article
Tariquidar-Induced P-Glycoprotein Inhibition at the Rat Blood--Brain Barrier Studied with (R)-<sup>11</sup>C-Verapamil and PET.
- Published in:
- Journal of Nuclear Medicine, 2008, v. 49, n. 8, p. 1328, doi. 10.2967/jnumed.108.051235
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- Publication type:
- Article
Combined PET and Microdialysis for In Vivo Assessment of Intracellular Drug Pharmacokinetics in Humans.
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- Journal of Nuclear Medicine, 2005, v. 46, n. 11, p. 1835
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- Publication type:
- Article
Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 12, p. 6514, doi. 10.3390/ijms23126514
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- Publication type:
- Article
Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8245, doi. 10.3390/ijms21218245
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- Publication type:
- Article
EGFR is required for FOS‐dependent bone tumor development via RSK2/CREB signaling.
- Published in:
- EMBO Molecular Medicine, 2018, v. 10, n. 11, p. N.PAG, doi. 10.15252/emmm.201809408
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- Publication type:
- Article
Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [11C]Metoclopramide in Mice.
- Published in:
- Pharmaceutical Research, 2021, v. 38, n. 1, p. 127, doi. 10.1007/s11095-021-03002-2
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- Publication type:
- Article
PET and SPET tracers for mapping the cardiac nervous system.
- Published in:
- European Journal of Nuclear Medicine & Molecular Imaging, 2002, v. 29, n. 3, p. 416, doi. 10.1007/s002590100640
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- Publication type:
- Article
Age dependency of cerebral P-gp function measured with ( R)-[<sup>11</sup>C]verapamil and PET.
- Published in:
- European Journal of Clinical Pharmacology, 2009, v. 65, n. 9, p. 941, doi. 10.1007/s00228-009-0709-5
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- Publication type:
- Article
Humanization of the Blood-Brain Barrier Transporter ABCB1 in Mice Disrupts Genomic Locus -- Lessons from Three Unsuccessful Approaches.
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- European Journal of Microbiology & Immunology, 2018, v. 8, n. 3, p. 78, doi. 10.1556/1886.2018.00008
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- Publication type:
- Article
Blood-brain barrier p-glycoprotein function in Alzheimer's disease
- Published in:
- 2011
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- Publication type:
- Abstract
Repurposing 99mTc‐mebrofenin as a probe for molecular imaging of hepatocyte transporters.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 12, p. 1, doi. 10.2967/jnumed.120.261321
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- Publication type:
- Article
Repurposing <sup>99m</sup>Tc‐mebrofenin as a probe for molecular imaging of hepatocyte transporters.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 11, p. 1, doi. 10.2967/jnumed.120.261321
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- Publication type:
- Article
Repurposing 99mTc‐mebrofenin as a probe for molecular imaging of hepatocyte transporters.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 11, p. 1, doi. 10.2967/jnumed.120.261321
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- Publication type:
- Article
Repurposing <sup>99m</sup>Tc‐mebrofenin as a probe for molecular imaging of hepatocyte transporters.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 10, p. 1, doi. 10.2967/jnumed.120.261321
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- Publication type:
- Article
Repurposing <sup>99m</sup>Tc-mebrofenin as a probe for molecular imaging of hepatocyte transporters.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 8, p. 1, doi. 10.2967/jnumed.120.261321
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- Publication type:
- Article
Repurposing <sup>99m</sup>Tc-mebrofenin as a probe for molecular imaging of hepatocyte transporters.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 7, p. 1, doi. 10.2967/jnumed.120.261321
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- Publication type:
- Article
Repurposing <sup>99m</sup>Tc-mebrofenin as a probe for molecular imaging of hepatocyte transporters.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 6, p. 1, doi. 10.2967/jnumed.120.261321
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- Publication type:
- Article
Repurposing <sup>99m</sup>Tc-mebrofenin as a probe for molecular imaging of hepatocyte transporters.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 5, p. 1, doi. 10.2967/jnumed.120.261321
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- Publication type:
- Article
Assessing the Activity of Multidrug Resistance-Associated Protein 1 at the Lung Epithelial Barrier.
- Published in:
- Journal of Nuclear Medicine, 2020, v. 61, n. 12, p. 1, doi. 10.2967/jnumed.120.244038
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- Publication type:
- Article
Assessing the Activity of Multidrug Resistance-Associated Protein 1 at the Lung Epithelial Barrier.
- Published in:
- Journal of Nuclear Medicine, 2020, v. 61, n. 11, p. 1, doi. 10.2967/jnumed.120.244038
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- Publication type:
- Article
Assessing the Activity of Multidrug Resistance-Associated Protein 1 at the Lung Epithelial Barrier.
- Published in:
- Journal of Nuclear Medicine, 2020, v. 61, n. 10, p. 1, doi. 10.2967/jnumed.120.244038
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- Publication type:
- Article
Assessing the Activity of Multidrug Resistance-Associated Protein 1 at the Lung Epithelial Barrier.
- Published in:
- Journal of Nuclear Medicine, 2020, v. 61, n. 9, p. 1, doi. 10.2967/jnumed.120.244038
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- Publication type:
- Article
Assessing the Activity of Multidrug Resistance-Associated Protein 1 at the Lung Epithelial Barrier.
- Published in:
- Journal of Nuclear Medicine, 2020, v. 61, n. 7, p. 1, doi. 10.2967/jnumed.120.244038
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- Publication type:
- Article
Assessing the Activity of Multidrug Resistance-Associated Protein 1 at the Lung Epithelial.
- Published in:
- Journal of Nuclear Medicine, 2020, v. 61, n. 6, p. 1, doi. 10.2967/jnumed.120.244038
- By:
- Publication type:
- Article
Assessing the Activity of Multidrug Resistance-Associated Protein 1 at the Lung Epithelial Barrier.
- Published in:
- Journal of Nuclear Medicine, 2020, v. 61, n. 5, p. 1, doi. 10.2967/jnumed.120.244038
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- Publication type:
- Article
Imaging P-glycoprotein Induction at the Blood-Brain Barrier of a Beta-Amyloidosis Mouse Model with <sup>11</sup>C-Metoclopramide PET.
- Published in:
- Journal of Nuclear Medicine, 2019, v. 60, n. 12, p. 1, doi. 10.2967/jnumed.119.237198
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- Publication type:
- Article
Impact of P-glycoprotein Function on the Brain Kinetics of the Weak Substrate <sup>11</sup>C-Metoclopramide Assessed with PET Imaging in Humans.
- Published in:
- Journal of Nuclear Medicine, 2019, v. 60, n. 12, p. 1, doi. 10.2967/jnumed.118.219972
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- Publication type:
- Article
Impact of P-Glycoprotein Function on the Brain Kinetics of the Weak Substrate <sup>11</sup>C-Metoclopramide Assessed with PET Imaging in Humans.
- Published in:
- Journal of Nuclear Medicine, 2019, v. 60, n. 7, p. 985, doi. 10.2967/jnumed.118.219972
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- Publication type:
- Article
A Proof-of-Concept Study to Inhibit ABCG2- and ABCB1- Mediated Efflux Transport at the Human Blood–Brain Barrier.
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- Journal of Nuclear Medicine, 2019, v. 60, n. 4, p. 486, doi. 10.2967/jnumed.118.216432
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- Publication type:
- Article
P-Glycoprotein (ABCB1) Inhibits the Influx and Increases the Efflux of <sup>11</sup>C-Metoclopramide Across the Blood–Brain Barrier: A PET Study on Nonhuman Primates.
- Published in:
- Journal of Nuclear Medicine, 2018, v. 59, n. 10, p. 1609, doi. 10.2967/jnumed.118.210104
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- Publication type:
- Article
Assessment of P-Glycoprotein Transport Activity at the Human Blood-Retina Barrier with (R)-<sup>11</sup>C-Verapamil PET.
- Published in:
- Journal of Nuclear Medicine, 2017, v. 58, n. 4, p. 678, doi. 10.2967/jnumed.116.182147
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- Publication type:
- Article
Strategies to Inhibit ABCB1- and ABCG2-Mediated Efflux Transport of Erlotinib at the Blood–Brain Barrier: A PET Study on Nonhuman Primates.
- Published in:
- Journal of Nuclear Medicine, 2017, v. 58, n. 1, p. 117, doi. 10.2967/jnumed.116.178665
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- Publication type:
- Article
Whole-Body Distribution and Radiation Dosimetry of <sup>11</sup>C-Elacridar and <sup>11</sup>C-Tariquidar in Humans.
- Published in:
- Journal of Nuclear Medicine, 2016, v. 57, n. 8, p. 1265, doi. 10.2967/jnumed.116.175182
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- Publication type:
- Article
Breast Cancer Resistance Protein and P-Glycoprotein Influence In Vivo Disposition of <sup>11</sup>C-Erlotinib.
- Published in:
- Journal of Nuclear Medicine, 2015, v. 56, n. 12, p. 1930, doi. 10.2967/jnumed.115.161273
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- Publication type:
- Article
Interaction of <sup>11</sup>C-Tariquidar and <sup>11</sup>C-Elacridar with P-Glycoprotein and Breast Cancer Resistance Protein at the Human Blood-Brain Barrier.
- Published in:
- Journal of Nuclear Medicine, 2013, v. 54, n. 8, p. 1181, doi. 10.2967/jnumed.112.118232
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- Publication type:
- Article
Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-52213-6
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- Publication type:
- Article
Microdosing as a Potential Tool to Enhance Clinical Development of Novel Antibiotics: A Tissue and Plasma PK Feasibility Study with Ciprofloxacin.
- Published in:
- 2022
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- Publication type:
- journal article
[ 11 C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2024, v. 44, n. 1, p. 142, doi. 10.1177/0271678X231202336
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- Publication type:
- Article
Comparative vulnerability of PET radioligands to partial inhibition of P-glycoprotein at the blood-brain barrier: A criterion of choice?
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2022, v. 42, n. 1, p. 175, doi. 10.1177/0271678X211045444
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- Publication type:
- Article
Complete inhibition of ABCB1 and ABCG2 at the blood–brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [ 11 C]erlotinib.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2021, v. 41, n. 7, p. 1634, doi. 10.1177/0271678X20965500
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- Publication type:
- Article
Measurement of cerebral ABCC1 transport activity in wild-type and APP/PS1-21 mice with positron emission tomography.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2020, v. 40, n. 5, p. 954, doi. 10.1177/0271678X19854541
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- Publication type:
- Article