Works by Lane, Thomas E.

Results: 51

Innate Immune Responses and Viral-Induced Neurologic Disease.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 1, p. 3, doi. 10.3390/jcm8010003

By:

Cheng, Yuting;
Skinner, Dominic D.;
Lane, Thomas E.

Publication type:

Article

Microglia influence immune responses and restrict neurologic disease in response to central nervous system infection by a neurotropic murine coronavirus.

Published in:

Frontiers in Cellular Neuroscience, 2023, p. 01, doi. 10.3389/fncel.2023.1291255

By:

Syage, Amber;
Pachow, Collin;
Yuting Cheng;
Mangale, Vrushali;
Green, Kim N.;
Lane, Thomas E.

Publication type:

Article

The 2020 FASEB Science Research Conference on Translational Neuroimmunology: From Mechanisms to Therapeutics, June 29‐30, 2020.

Published in:

FASEB Journal, 2020, v. 34, n. 11, p. 14064, doi. 10.1096/fj.202002065

By:

Lane, Thomas E.;
Segal, Benjamin M.

Publication type:

Article

Coronavirus infection of the central nervous system: host–virus stand-off.

Published in:

Nature Reviews Microbiology, 2006, v. 4, n. 2, p. 121, doi. 10.1038/nrmicro1343

By:

Bergmann, Cornelia C.;
Lane, Thomas E.;
Stohlman, Stephen A.

Publication type:

Article

Imaging Axonal Degeneration and Repair in Preclinical Animal Models of Multiple Sclerosis.

Published in:

Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00189

By:

Yandamuri, Soumya S.;
Lane, Thomas E.;
Ogura, Hideki;
Arima, Yasunobu

Publication type:

Article

ELR(+) chemokine signaling in host defense and disease in a viral model of central nervous system disease.

Published in:

Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00165

By:

Hosking, Martin P.;
Lane, Thomas E.

Publication type:

Article

ELR (+) chemokine signaling in host defense and disease in a viral model of central nervous system disease.

Published in:

Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00165

By:

Hosking, Martin P.;
Lane, Thomas E.

Publication type:

Article

Activating Receptor NKG2D Targets RAE-1-Expressing Allogeneic Neural Precursor Cells in a Viral Model of Multiple Sclerosis.

Published in:

Stem Cells, 2014, v. 32, n. 10, p. 2690, doi. 10.1002/stem.1760

By:

Weinger, Jason G.;
Plaisted, Warren C.;
Maciejewski, Sonia M.;
Lanier, Lewis L.;
Walsh, Craig M.;
Lane, Thomas E.

Publication type:

Article

Promoting remyelination: utilizing a viral model of demyelination to assess cell-based therapies.

Published in:

Expert Review of Neurotherapeutics, 2014, v. 14, n. 10, p. 1169, doi. 10.1586/14737175.2014.955854

By:

Marro, Brett S;
Blanc, Caroline A;
Loring, Jeanne F;
Cahalan, Michael D;
Lane, Thomas E

Publication type:

Article

CXCR2 Signaling and Remyelination in Preclinical Models of Demyelination.

Published in:

DNA & Cell Biology, 2020, v. 39, n. 1, p. 3, doi. 10.1089/dna.2019.5182

By:

Skinner, Dominic D.;
Lane, Thomas E.

Publication type:

Article

Cystatin F attenuates neuroinflammation and demyelination following murine coronavirus infection of the central nervous system.

Published in:

Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03153-0

By:

Syage, Amber R.;
Pachow, Collin;
Murray, Kaitlin M.;
Henningfield, Caden;
Fernandez, Kellie;
Du, Annie;
Cheng, Yuting;
Olivarria, Gema;
Kawauchi, Shimako;
MacGregor, Grant R.;
Green, Kim N.;
Lane, Thomas E.

Publication type:

Article

Promoting remyelination through cell transplantation therapies in a model of viral‐induced neurodegenerative disease.

Published in:

Developmental Dynamics, 2019, v. 248, n. 1, p. 43, doi. 10.1002/dvdy.24658

By:

Mangale, Vrushali;
McIntyre, Laura L.;
Walsh, Craig M.;
Loring, Jeanne F.;
Lane, Thomas E.

Publication type:

Article

CXCL10 and trafficking of virus-specific T cells during coronavirus-induced demyelination.

Published in:

Autoimmunity, 2009, v. 42, n. 6, p. 484, doi. 10.1080/08916930902810708

By:

Stiles, Linda N.;
Liu, Michael T.;
Kane, Joy A. C.;
Lane, Thomas E.

Publication type:

Article

DRAK2 regulates memory T cell responses following murine coronavirus infection.

Published in:

Autoimmunity, 2007, v. 40, n. 7, p. 483, doi. 10.1080/08916930701651139

By:

Schaumburg, Chris S.;
Gatzka, Martina;
Walsh, Craig M.;
Lane, Thomas E.

Publication type:

Article

Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment.

Published in:

European Journal of Immunology, 2018, v. 48, n. 7, p. 1199, doi. 10.1002/eji.201747442

By:

Grist, Jonathan J.;
Marro, Brett S.;
Skinner, Dominic D.;
Syage, Amber R.;
Worne, Colleen;
Doty, Daniel J.;
Fujinami, Robert S.;
Lane, Thomas E.

Publication type:

Article

Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis.

Published in:

PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0157620

By:

Plaisted, Warren C.;
Zavala, Angel;
Hingco, Edna;
Tran, Ha;
Coleman, Ronald;
Lane, Thomas E.;
Loring, Jeanne F.;
Walsh, Craig M.

Publication type:

Article

Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells.

Published in:

Glia (0894-1491), 2014, v. 62, n. 9, p. 1418, doi. 10.1002/glia.22689

By:

Chucair‐Elliott, Ana J.;
Conrady, Christopher;
Zheng, Min;
Kroll, Chandra M.;
Lane, Thomas E.;
Carr, Daniel J. J.

Publication type:

Article

CXCR4 signaling regulates remyelination by endogenous oligodendrocyte progenitor cells in a viral model of demyelination.

Published in:

Glia (0894-1491), 2011, v. 59, n. 12, p. 1813, doi. 10.1002/glia.21225

By:

Carbajal, Kevin S.;
Miranda, Juan L.;
Tsukamoto, Michelle R.;
Lane, Thomas E.

Publication type:

Article

CXCR2 signaling protects oligodendrocyte progenitor cells from IFN-γ/CXCL10-mediated apoptosis.

Published in:

Glia (0894-1491), 2011, v. 59, n. 10, p. 1518, doi. 10.1002/glia.21195

By:

Tirotta, Emanuele;
Ransohoff, Richard M.;
Lane, Thomas E.

Publication type:

Article

Chronic Systemic Infection Exacerbates Ischemic Brain Damage via a CCL5 (Regulated on Activation, Normal T-Cell Expressed and Secreted)-Mediated Proinflammatory Response in Mice.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 30, p. 10086, doi. 10.1523/JNEUROSCI.1227-10.2010

By:

Dénes, Ádám;
Humphreys, Neil;
Lane, Thomas E.;
Grencis, Richard;
Rothwell, Nancy

Publication type:

Article

Myelin Repair Is Accelerated by Inactivating CXCR2 on Nonhematopoietic Cells.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 27, p. 9074, doi. 10.1523/JNEUROSCI.1238-10.2010

By:

LiPing Liu;
Darnall, Lindsey;
Taofang Hu;
Choi, Karen;
Lane, Thomas E.;
Ransohoff, Richard M.

Publication type:

Article

FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination.

Published in:

Journal of Neuroinflammation, 2014, v. 11, n. 1, p. 1, doi. 10.1186/s12974-014-0138-y

By:

Blanc, Caroline A.;
Rosen, Hugh;
Lane, Thomas E.

Publication type:

Article

FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination.

Published in:

2014

By:

Blanc, Caroline A;
Rosen, Hugh;
Lane, Thomas E

Publication type:

journal article

EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria.

Published in:

PLoS Pathogens, 2020, v. 16, n. 1, p. 1, doi. 10.1371/journal.ppat.1008261

By:

Darling, Thayer K.;
Mimche, Patrice N.;
Bray, Christian;
Umaru, Banlanjo;
Brady, Lauren M.;
Stone, Colleen;
Eboumbou Moukoko, Carole Else;
Lane, Thomas E.;
Ayong, Lawrence S.;
Lamb, Tracey J.

Publication type:

Article

CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis.

Published in:

Nature Neuroscience, 2010, v. 13, n. 3, p. 319, doi. 10.1038/nn.2491

By:

Liu, LiPing;
Belkadi, Abdelmadjid;
Darnall, Lindsey;
Taofang Hu;
Drescher, Caitlin;
Cotleur, Anne C.;
Padovani-Claudio, Dolly;
Tao He;
Choi, Karen;
Lane, Thomas E.;
Miller, Robert H.;
Ransohoff, Richard M.

Publication type:

Article

Adenovirus-Mediated Expression of CXCL10 in the Central Nervous System Results in T-Cell Recruitment and Limited Neuropathology.

Published in:

Journal of NeuroVirology, 2003, v. 9, n. 3, p. 315, doi. 10.1080/13550280390201029

By:

Trifilo, Matthew J.;
Lane, Thomas E.

Publication type:

Article

Lack of nitric oxide synthase type 2 (NOS2) results in reduced neuronal apoptosis and mortality following mouse hepatitis virus infection of the central nervous system.

Published in:

Journal of NeuroVirology, 2002, v. 8, n. 1, p. 58, doi. 10.1080/135502802317247820

By:

Chen, Benjamin P.;
Lane, Thomas E.

Publication type:

Article

COVID‐19 and the impact on Alzheimer's disease pathology.

Published in:

Journal of Neurochemistry, 2024, v. 168, n. 10, p. 3415, doi. 10.1111/jnc.15985

By:

Furman, Susana;
Green, Kim;
Lane, Thomas E.

Publication type:

Article

Chitinase Dependent Control of Protozoan Cyst Burden in the Brain.

Published in:

PLoS Pathogens, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.ppat.1002990

By:

Nance, J. Philip;
Vannella, Kevin M.;
Worth, Danielle;
David, Clément;
Carter, David;
Noor, Shahani;
Hubeau, Cedric;
Fitz, Lori;
Lane, Thomas E.;
Wynn, Thomas A.;
Wilson, Emma H.

Publication type:

Article

The Role of Chemokines during Viral Infection of the CNS.

Published in:

PLoS Pathogens, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.ppat.1000937

By:

Hosking, Martin P.;
Lane, Thomas E.

Publication type:

Article

A Protective Role for ELR+ Chemokines during Acute Viral Encephalomyelitis.

Published in:

PLoS Pathogens, 2009, v. 5, n. 11, p. 1, doi. 10.1371/journal.ppat.1000648

By:

Hosking, Martin P.;
Liping Liu;
Ransohoff, Richard M.;
Lane, Thomas E.

Publication type:

Article

Reversal of deficits in aged skeletal muscle during disuse and recovery in response to treatment with a secrotome product derived from partially differentiated human pluripotent stem cells.

Published in:

GeroScience, 2021, v. 43, n. 6, p. 2635, doi. 10.1007/s11357-021-00423-0

By:

Fix, Dennis K.;
Mahmassani, Ziad S.;
Petrocelli, Jonathan J.;
de Hart, Naomi M.M.P.;
Ferrara, Patrick J.;
Painter, Jessie S.;
Nistor, Gabriel;
Lane, Thomas E.;
Keirstead, Hans S.;
Drummond, Micah J.

Publication type:

Article

Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice.

Published in:

Aging Cell, 2024, v. 23, n. 6, p. 1, doi. 10.1111/acel.14144

By:

Fennel, Zachary J.;
Bourrant, Paul‐Emile;
Kurian, Anu Susan;
Petrocelli, Jonathan J.;
de Hart, Naomi M. M. P.;
Yee, Elena M.;
Boudina, Sihem;
Keirstead, Hans S.;
Nistor, Gabrielle;
Greilach, Scott A.;
Berchtold, Nicole C.;
Lane, Thomas E.;
Drummond, Micah J.

Publication type:

Article

Neutralization of chemokines RANTES and MIG increases virus antigen expression and spinal cord pathology during Theiler's virus infection.

Published in:

International Immunology, 2005, v. 17, n. 5, p. 569, doi. 10.1093/intimm/dxh236

By:

Daren R. Ure;
Thomas E. Lane;
Michael T. Liu;
Moses Rodriguez

Publication type:

Article

Generation of an Inducible Destabilized‐Domain Cre Mouse Line to Target Disease Associated Microglia.

Published in:

Glia (0894-1491), 2025, v. 73, n. 6, p. 1272, doi. 10.1002/glia.70004

By:

Henningfield, Caden M.;
Ngo, Minh;
Murray, Kaitlin M.;
Kwang, Nellie E.;
Tsourmas, Kate I.;
Neumann, Jonathan;
Pashkutz, Zachary A.;
Kawauchi, Shimako;
Swarup, Vivek;
Lane, Thomas E.;
MacGregor, Grant R.;
Green, Kim N.

Publication type:

Article

MAC2 is a long‐lasting marker of peripheral cell infiltrates into the mouse CNS after bone marrow transplantation and coronavirus infection.

Published in:

Glia (0894-1491), 2022, v. 70, n. 5, p. 875, doi. 10.1002/glia.24144

By:

Hohsfield, Lindsay A.;
Tsourmas, Kate I.;
Ghorbanian, Yasamine;
Syage, Amber R.;
Jin Kim, Sung;
Cheng, Yuting;
Furman, Susana;
Inlay, Matthew A.;
Lane, Thomas E.;
Green, Kim N.

Publication type:

Article

Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system.

Published in:

Glia (0894-1491), 2020, v. 68, n. 11, p. 2345, doi. 10.1002/glia.23844

By:

Mangale, Vrushali;
Syage, Amber R.;
Ekiz, H. Atakan;
Skinner, Dominic D.;
Cheng, Yuting;
Stone, Colleen L.;
Brown, R. Marshall;
O'Connell, Ryan M.;
Green, Kim N.;
Lane, Thomas E.

Publication type:

Article

SARS-CoV-2 infection of human cortical cells is influenced by the interaction between aneuploidy and biological sex: insights from a Down syndrome in vitro model.

Published in:

Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02895-2

By:

Lioudyno, Maria I.;
Sevrioukov, Evgueni A.;
Olivarria, Gema M.;
Hitchcock, Lauren;
Javonillo, Dominic I.;
Campos, Sydney M.;
Rivera, Isabel;
Wright, Sierra T.;
Head, Elizabeth;
Fortea, Juan;
Wisniewski, Thomas;
Cuello, A. Claudio;
Do Carmo, Sonia;
Lane, Thomas E.;
Busciglio, Jorge

Publication type:

Article

Anti-viral effector T cell responses and trafficking are not dependent upon DRAK2 signaling following viral infection of the central nervous system.

Published in:

Autoimmunity, 2007, v. 40, n. 1, p. 54, doi. 10.1080/08916930600996700

By:

Ramos, Stephanie J.;
Hardison, Jenny L.;
Stiles, Linda N.;
Lane, Thomas E.;
Walsh, Craig M.

Publication type:

Article

Microbes and Autoimmunity.

Published in:

Autoimmunity, 2004, v. 37, n. 5, p. 373, doi. 10.1080/08916930410001716086

By:

Lane, Thomas E.

Publication type:

Article

Distinct roles for IP-10/CXCL10 in three animal models, Theiler's virus infection, EAE, and MHV infection, for multiple sclerosis: implication of differing roles for IP-10.

Published in:

Multiple Sclerosis (13524585), 2004, v. 10, n. 1, p. 26, doi. 10.1191/1352458504ms982oa

By:

Tsunoda, Ikuo;
Lane, Thomas E.;
Blackett, Jana;
Fujinami, Robert S.

Publication type:

Article

WSX-1 Signalling Inhibits CD4<sup>+</sup> T Cell Migration to the Liver during Malaria Infection by Repressing Chemokine-Independent Pathways.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078486

By:

Villegas-Mendez, Ana;
Gwyer Findlay, Emily;
de Souza, J. Brian;
Grady, Lisa-Marie;
Saris, Christiaan J.;
Lane, Thomas E.;
Riley, Eleanor M.;
Couper, Kevin N.

Publication type:

Article

CXCR2 Signaling Protects Oligodendrocytes and Restricts Demyelination in a Mouse Model of Viral-Induced Demyelination.

Published in:

PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0011340

By:

Hosking, Martin P.;
Tirotta, Emanuele;
Ransohoff, Richard M.;
Lane, Thomas E.

Publication type:

Article

Chemokine CC Receptor 2 Is Important for Acute Control of Cardiac Parasitism but Does Not Contribute to Cardiac Inflammation after Infection with Trypanosoma cruzi.

Published in:

Journal of Infectious Diseases, 2006, v. 193, n. 11, p. 1584, doi. 10.1086/503812

By:

Hardison, Jenny L.;
Kuziel, William A.;
Manning, Jerry E.;
Lane, Thomas E.

Publication type:

Article

THE ADAPTIVE IMMUNE SYSTEM CRITICALLY REGULATES ALZHEIMER’S DISEASE PATHOGENESIS BY MODULATING MICROGLIAL FUNCTION.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P463, doi. 10.1016/j.jalz.2016.06.906

By:

Marsh, Samuel E.;
Karimzadeh, Alborz;
Abud, Edsel M.;
Lakatos, Anita;
Yeung, Stephen T.;
Davtyan, Hayk;
Fote, Gianna;
Lau, Lydia;
Weinger, Jason G.;
Lane, Thomas E.;
Poon, Wayne W.;
Inlay, Matthew A.;
Blurton-Jones, Mathew

Publication type:

Article

Evaluating the role of chemokines and chemokine receptors involved in coronavirus infection.

Published in:

Expert Review of Clinical Immunology, 2022, v. 18, n. 1, p. 57, doi. 10.1080/1744666X.2022.2017282

By:

Olivarria, Gema;
Lane, Thomas E.

Publication type:

Article

T cell-selective deletion of Oct1 protects animals from autoimmune neuroinflammation while maintaining neurotropic pathogen response.

Published in:

2019

By:

Kim, Heejoo;
Dickey, Laura;
Stone, Colleen;
Jafek, Jillian L.;
Lane, Thomas E.;
Tantin, Dean

Publication type:

journal article

Sustained Infiltration of Neutrophils Into the CNS Results in Increased Demyelination in a Viral-Induced Model of Multiple Sclerosis.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.931388

By:

Skinner, Dominic D.;
Syage, Amber R.;
Olivarria, Gema M.;
Stone, Colleen;
Hoglin, Bailey;
Lane, Thomas E.

Publication type:

Article

CXCL10/CXCR3-mediated responses promote immunity to respiratory syncytial virus infection by augmenting dendritic cell and CD8.

Published in:

European Journal of Immunology, 2008, v. 38, n. 8, p. 2168, doi. 10.1002/eji.200838155

By:

Lindell, Dennis M.;
Lane, Thomas E.;
Lukacs, Nicholas W.

Publication type:

Article

Differential roles for CXCR3 in CD4.

Published in:

European Journal of Immunology, 2006, v. 36, n. 3, p. 613, doi. 10.1002/eji.200535509

By:

Stiles, Linda N.;
Hosking, Martin P.;
Edwards, Robert A.;
Strieter, Robert M.;
Lane, Thomas E.

Publication type:

Article