Works matching AU Landreth, Gary
Results: 109
TREM2 is required for microglial instruction of astrocytic synaptic engulfment in neurodevelopment.
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- Glia, 2019, v. 67, n. 10, p. 1873, doi. 10.1002/glia.23664
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- Article
PPARβ/δ‐agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes.
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- Glia, 2019, v. 67, n. 1, p. 146, doi. 10.1002/glia.23534
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- Article
Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice.
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- Journal of Neuroscience, 2018, v. 38, n. 30, p. 6640, doi. 10.1523/JNEUROSCI.0515-17.2018
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- Article
Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.
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- Journal of Neuroscience, 2017, v. 37, n. 3, p. 637, doi. 10.1523/JNEUROSCI.2110-16.2017
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- Article
ERK2 Alone Drives Inflammatory Pain But Cooperates with ERK1 in Sensory Neuron Survival.
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- Journal of Neuroscience, 2015, v. 35, n. 25, p. 9491, doi. 10.1523/JNEUROSCI.4404-14.2015
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- Article
Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease.
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- Journal of Neuroscience, 2015, v. 35, n. 24, p. 9173, doi. 10.1523/JNEUROSCI.1000-15.2015
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- Article
Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation.
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- Journal of Neuroscience, 2015, v. 35, n. 17, p. 6836, doi. 10.1523/JNEUROSCI.4196-14.2015
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- Article
Nuclear Receptors License Phagocytosis by Trem2<sup>+</sup> Myeloid Cells in Mouse Models of Alzheimer's Disease.
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- Journal of Neuroscience, 2015, p. 6532, doi. 10.1523/JNEUROSCI.4586-14.2015
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- Article
The 16p11.2 Deletion Mouse Model of Autism Exhibits Altered Cortical Progenitor Proliferation and Brain Cytoarchitecture Linked to the ERK MAPK Pathway.
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- Journal of Neuroscience, 2015, v. 35, n. 7, p. 3190, doi. 10.1523/JNEUROSCI.4864-13.2015
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- Article
Opposing Effects of Membrane-Anchored CX3CL1 on Amyloid and Tau Pathologies via the p38 MAPK Pathway.
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- Journal of Neuroscience, 2014, v. 34, n. 37, p. 12538, doi. 10.1523/JNEUROSCI.0853-14.2014
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- Article
Loss of Interleukin Receptor-Associated Kinase 4 Signaling Suppresses Amyloid Pathology and Alters Microglial Phenotype in a Mouse Model of Alzheimer's Disease.
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- Journal of Neuroscience, 2012, v. 32, n. 43, p. 15112, doi. 10.1523/JNEUROSCI.1729-12.2012
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- Article
Neural-specific deletion of ERK2 results in frontal cortical neuropil thread formation and astrogliosis.
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- FASEB Journal, 2007, v. 21, n. 5, p. A24, doi. 10.1096/fasebj.21.5.a24
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- Article
Noradrenergic depletion increases inflammatory responses in brain: effects on IκB and HSP70 expression.
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- Journal of Neurochemistry, 2003, v. 85, n. 2, p. 387, doi. 10.1046/j.1471-4159.2003.01694.x
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- Article
Casein Kinase II Phosphorylates the Neural Cell Adhesion Molecule L1.
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- Journal of Neurochemistry, 1996, v. 66, n. 2, p. 779, doi. 10.1046/j.1471-4159.1996.66020779.x
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- Article
Characterization of a Nerve Growth Factor-Stimulated Protein Kinase in PC12 Cells Which Phosphorylates Microtubule-Associated Protein 2 and pp250.
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- Journal of Neurochemistry, 1990, v. 55, n. 2, p. 514, doi. 10.1111/j.1471-4159.1990.tb04165.x
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- Article
Selective Inhibition of Nerve Growth Factor-Stimulated Protein Kinases by K-252a and 5′- S-Methyladenosine in PC12 Cells.
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- Journal of Neurochemistry, 1989, v. 53, n. 3, p. 800, doi. 10.1111/j.1471-4159.1989.tb11776.x
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- Article
Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer's disease.
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- 2018
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- journal article
The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications.
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- 2008
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- journal article
The Role of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) in Alzheimer's Disease.
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- CNS Drugs, 2008, v. 22, n. 1, p. 1, doi. 10.2165/00023210-200822010-00001
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- Article
TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.
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- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0216-6
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- Article
TREM2 in Neurodegenerative Diseases.
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- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0197-5
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- Article
In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis.
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- Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-13
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- Article
Activation of the nuclear receptor PPARδ is neuroprotective in a transgenic mouse model of Alzheimer's disease through inhibition of inflammation.
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- Journal of Neuroinflammation, 2015, v. 12, n. 1, p. 323, doi. 10.1186/s12974-014-0229-9
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- Article
The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease.
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- Journal of Neuroinflammation, 2006, v. 3, p. 30, doi. 10.1186/1742-2094-3-30
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- Article
PPARγ, neuroinflammation, and disease.
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- Journal of Neuroinflammation, 2004, v. 1, p. 5, doi. 10.1186/1742-2094-1-5
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- Article
Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised.
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- Journal of Neuroinflammation, 2004, v. 1, p. 11, doi. 10.1186/1742-2094-1-11
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- Article
ERK Signaling Is Essential for Macrophage Development.
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- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140064
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- Article
Peroxisome proliferator-activated receptor-γ agonists prevent experimental autoimmune encephalomyelitis.
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- Annals of Neurology, 2002, v. 51, n. 6, p. 694, doi. 10.1002/ana.10206
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- Article
Role for peroxisome proliferator-activated receptor-γ in Alzheimer's disease.
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- Annals of Neurology, 2001, v. 49, n. 2, p. 276, doi. 10.1002/1531-8249(20010201)49:2<276::AID-ANA53>3.0.CO;2-5
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- Article
Secondary endpoint and responder analyses in a study of rosiglitazone XR in APOE4-stratified subjects with mild-to-moderate Alzheimer's disease
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- 2009
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- Abstract
Safety and tolerability of rosiglitazone XR in a randomised, placebo-controlled study in APOE4-stratified subjects with mild-to-moderate Alzheimer's disease
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- 2009
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- Abstract
Effects of rosiglitazone as monotherapy in APOE4-stratified subjects with mild-to-moderate Alzheimer's disease
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- 2009
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- Abstract
S1-03-02: Liver X Receptors act to facilitate Aβ clearance and suppress inflammation in the Alzheimer's disease brain
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- 2008
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- Abstract
P3-360: Vav is required for β-amyloid-stimulated NADPH oxidase activation and phagosome formation in primary microglia
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- 2006
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- Abstract
P2-408: A double-blind, placebo-controlled, 18-month pilot study of the PPAR-gamma agonist pioglitazone in Alzheimer’s disease
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- 2006
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- Abstract
P3-360: Vav is required for β-amyloid-stimulated NADPH oxidase activation and phagosome formation in primary microglia
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- 2006
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- Abstract
P2-408: A double-blind, placebo-controlled, 18-month pilot study of the PPAR-gamma agonist pioglitazone in Alzheimer’s disease
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- 2006
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- Abstract
Targeting innate immunity for neurodegenerative disorders of the central nervous system.
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- Journal of Neurochemistry, 2016, v. 138, n. 5, p. 653, doi. 10.1111/jnc.13667
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- Article
Muscle-Derived Extracellular Signal-Regulated Kinases 1 and 2 Are Required for the Maintenance of Adult Myofibers and Their Neuromuscular Junctions.
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- Molecular & Cellular Biology, 2015, v. 35, n. 7, p. 1238, doi. 10.1128/MCB.01071-14
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- Article
Cover Image, Volume 36, Issue 5.
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- NMR in Biomedicine, 2023, v. 36, n. 5, p. 1, doi. 10.1002/nbm.4943
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- Article
Integrating multimodality magnetic resonance imaging to the Allen Mouse Brain Common Coordinate Framework.
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- NMR in Biomedicine, 2023, v. 36, n. 5, p. 1, doi. 10.1002/nbm.4887
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- Article
Chronic impairment of ERK signaling in glutamatergic neurons of the forebrain does not affect spatial memory retention and LTP in the same manner as acute blockade of the ERK pathway.
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- Hippocampus, 2017, v. 27, n. 12, p. 1239, doi. 10.1002/hipo.22769
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- Article
FGF and ERK signaling coordinately regulate mineralization-related genes and play essential roles in osteocyte differentiation.
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- Journal of Bone & Mineral Metabolism, 2012, v. 30, n. 1, p. 19, doi. 10.1007/s00774-011-0288-2
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- Article
CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease.
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- Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00545-9
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- Article
Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00409-0
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- Article
The <italic>T</italic>rem<italic>2</italic> R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0262-8
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- Article
The role of microglia in amyloid clearance from the AD brain.
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- Journal of Neural Transmission, 2010, v. 117, n. 8, p. 949, doi. 10.1007/s00702-010-0433-4
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Phosphorylation of insulin receptors solubilized from rat skeletal muscle.
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- 1984
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- journal article
Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis.
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- Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02761-6
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- Article
L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1.
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- Journal of Cell Biology, 2002, v. 157, n. 7, p. 1223, doi. 10.1083/jcb.200203024
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- Article