Works by Lambrecht, Bart N.

Results: 156
    1

    Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

    Published in:
    Angewandte Chemie International Edition, 2025, v. 64, n. 28, p. 1, doi. 10.1002/anie.202506954
    By:
    • Chen, Yong;
    • De Lombaerde, Emily;
    • Bugler‐Lamb, Aimée;
    • Zhong, Zifu;
    • Schuijs, Martijn J.;
    • Gomez, Claudia M. Brenis;
    • De Baere, Jamie;
    • Gontsarik, Mark;
    • Lauwers, Heleen;
    • Deswarte, Kim;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • Guilliams, Martin;
    • De Geest, Bruno G.
    Publication type:
    Article
    2

    Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

    Published in:
    Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202506954
    By:
    • Chen, Yong;
    • De Lombaerde, Emily;
    • Bugler‐Lamb, Aimée;
    • Zhong, Zifu;
    • Schuijs, Martijn J.;
    • Gomez, Claudia M. Brenis;
    • De Baere, Jamie;
    • Gontsarik, Mark;
    • Lauwers, Heleen;
    • Deswarte, Kim;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • Guilliams, Martin;
    • De Geest, Bruno G.
    Publication type:
    Article
    3

    A20-Deficient Mast Cells Exacerbate Inflammatory Responses <i>In Vivo</i>.

    Published in:
    PLoS Biology, 2014, v. 12, n. 1, p. 1, doi. 10.1371/journal.pbio.1001762
    By:
    • Heger, Klaus;
    • Fierens, Kaat;
    • Vahl, J. Christoph;
    • Aszodi, Attila;
    • Peschke, Katrin;
    • Schenten, Dominik;
    • Hammad, Hamida;
    • Beyaert, Rudi;
    • Saur, Dieter;
    • van Loo, Geert;
    • Roers, Axel;
    • Lambrecht, Bart N.;
    • Kool, Mirjam;
    • Schmidt-Supprian, Marc
    Publication type:
    Article
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    Ym1 protein crystals promote type 2 immunity.

    Published in:
    eLife, 2024, p. 1, doi. 10.7554/eLife.90676
    By:
    • Heyndrickx, Ines;
    • Deswarte, Kim;
    • Verstraete, Kenneth;
    • Verschueren, Koen H. G.;
    • Smole, Ursula;
    • Aegerter, Helena;
    • Dansercoer, Ann;
    • Hammad, Hamida;
    • Savvides, Savvas N.;
    • Lambrecht, Bart N.
    Publication type:
    Article
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    Berichtigung: Sterilizing Immunity against SARS‐CoV‐2 Infection in Mice by a Single‐Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist‐Adjuvanted Recombinant Spike Protein Vaccine.

    Published in:
    Angewandte Chemie, 2021, v. 133, n. 31, p. 16878, doi. 10.1002/ange.202105635
    By:
    • Jangra, Sonia;
    • De Vrieze, Jana;
    • Choi, Angela;
    • Rathnasinghe, Raveen;
    • Laghlali, Gabriel;
    • Uvyn, Annemiek;
    • Van Herck, Simon;
    • Nuhn, Lutz;
    • Deswarte, Kim;
    • Zhong, Zifu;
    • Sanders, Niek N.;
    • Lienenklaus, Stefan;
    • David, Sunil A.;
    • Strohmeier, Shirin;
    • Amanat, Fatima;
    • Krammer, Florian;
    • Hammad, Hamida;
    • Lambrecht, Bart N.;
    • Coughlan, Lynda;
    • García‐Sastre, Adolfo
    Publication type:
    Article
    10

    Sterilizing Immunity against SARS‐CoV‐2 Infection in Mice by a Single‐Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist‐Adjuvanted Recombinant Spike Protein Vaccine.

    Published in:
    Angewandte Chemie, 2021, v. 133, n. 17, p. 9553, doi. 10.1002/ange.202015362
    By:
    • Jangra, Sonia;
    • De Vrieze, Jana;
    • Choi, Angela;
    • Rathnasinghe, Raveen;
    • Laghlali, Gabriel;
    • Uvyn, Annemiek;
    • Van Herck, Simon;
    • Nuhn, Lutz;
    • Deswarte, Kim;
    • Zhong, Zifu;
    • Sanders, Niek N.;
    • Lienenklaus, Stefan;
    • David, Sunil A.;
    • Strohmeier, Shirin;
    • Amanat, Fatima;
    • Krammer, Florian;
    • Hammad, Hamida;
    • Lambrecht, Bart N.;
    • Coughlan, Lynda;
    • García‐Sastre, Adolfo
    Publication type:
    Article
    11

    Amphiphile Polymer‐Lipidkonjugate zur potenten lymphatischen Anreicherung von TLR7/8‐Agonisten ermöglichen eine örtlich begrenzte Aktivierung des angeborenen Immunsystems.

    Published in:
    Angewandte Chemie, 2019, v. 131, n. 43, p. 15535, doi. 10.1002/ange.201905687
    By:
    • De Vrieze, Jana;
    • Louage, Benoit;
    • Deswarte, Kim;
    • Zhong, Zifu;
    • De Coen, Ruben;
    • Van Herck, Simon;
    • Nuhn, Lutz;
    • Kaas Frich, Camilla;
    • Zelikin, Alexander N.;
    • Lienenklaus, Stefan;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • David, Sunil A.;
    • De Geest, Bruno G.
    Publication type:
    Article
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    A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.

    Published in:
    Nature Genetics, 2011, v. 43, n. 9, p. 908, doi. 10.1038/ng.874
    By:
    • Matmati, Mourad;
    • Jacques, Peggy;
    • Maelfait, Jonathan;
    • Verheugen, Eveline;
    • Kool, Mirjam;
    • Sze, Mozes;
    • Geboes, Lies;
    • Louagie, Els;
    • McGuire, Conor;
    • Vereecke, Lars;
    • Chu, Yuanyuan;
    • Boon, Louis;
    • Staelens, Steven;
    • Matthys, Patrick;
    • Lambrecht, Bart N.;
    • Schmidt-Supprian, Marc;
    • Pasparakis, Manolis;
    • Elewaut, Dirk;
    • Beyaert, Rudi;
    • van Loo, Geert
    Publication type:
    Article
    18

    Proteomic Analysis of Exosomes Isolated from Human Malignant Pleural Effusions.

    Published in:
    American Journal of Respiratory Cell & Molecular Biology, 2004, v. 31, n. 1, p. 114, doi. 10.1165/rcmb.2003-0238OC
    By:
    • Bard, Martin P.;
    • Hegmans, Joost P.;
    • Hemmes, Annabrita;
    • Luider, Theo M.;
    • Willemsen, Rob;
    • Severijnen, Lies-Anne A.;
    • van Meerbeeck, Jan P.;
    • Burgers, Sjaak A.;
    • Hoogsteden, Henk C.;
    • Lambrecht, Bart N.
    Publication type:
    Article
    19
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    Role of B cell activating factor (BAFF) in Chronic Obstructive Pulmonary Disease.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 6, p. E1, doi. 10.1164/rccm.201501-0103oc
    By:
    • Seys, Leen J. M.;
    • Verhamme, Fien M.;
    • Schinwald, Anja;
    • Hammad, Hamida;
    • Cunoosamy, Danen Mootoosamy;
    • Bantsimba-Malanda, Claudie;
    • Sabirsh, Alan;
    • McCall, Eileen;
    • Flavell, Liz;
    • Herbst, Ronald;
    • Provoost, Sharen;
    • Lambrecht, Bart N.;
    • Joos, Guy F.;
    • Brusselle, Guy G.;
    • Bracke, Ken R.
    Publication type:
    Article
    21

    Role of B Cell-Activating Factor in Chronic Obstructive Pulmonary Disease.

    Published in:
    2015
    By:
    • Seys, Leen J. M.;
    • Verhamme, Fien M.;
    • Schinwald, Anja;
    • Hammad, Hamida;
    • Cunoosamy, Danen Mootoosamy;
    • Bantsimba-Malanda, Claudie;
    • Sabirsh, Alan;
    • McCall, Eileen;
    • Flavell, Liz;
    • Herbst, Ronald;
    • Provoost, Sharen;
    • Lambrecht, Bart N.;
    • Joos, Guy F.;
    • Brusselle, Guy G.;
    • Bracke, Ken R.
    Publication type:
    journal article
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    A conversation on allergy: recognizing the past and looking to the future.

    Published in:
    Immunology & Cell Biology, 2023, v. 101, n. 10, p. 936, doi. 10.1111/imcb.12688
    By:
    • Melén, Erik;
    • Lambrecht, Bart N;
    • Lloyd, Clare M;
    • Rothenberg, Marc E;
    • Kabashima, Kenji;
    • Luciani, Fabio;
    • Coquet, Jonathan M;
    • Ober, Carole;
    • Nawijn, Martijn C;
    • Platts‐Mills, Thomas;
    • von Mutius, Erika
    Publication type:
    Article
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    A CARD9 Founder Mutation Disrupts NF-κB Signaling by Inhibiting BCL10 and MALT1 Recruitment and Signalosome Formation.

    Published in:
    Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.02366
    By:
    • De Bruyne, Marieke;
    • Hoste, Levi;
    • Bogaert, Delfien J.;
    • Van den Bossche, Lien;
    • Tavernier, Simon J.;
    • Parthoens, Eef;
    • Migaud, Mélanie;
    • Konopnicki, Deborah;
    • Jean Cyr Yombi;
    • Lambrecht, Bart N.;
    • van Daele, Sabine;
    • de Medeiros, Ana Karina Alves;
    • Brochez, Lieve;
    • Beyaert, Rudi;
    • De Baere, Elfride;
    • Puel, Anne;
    • Casanova, Jean-Laurent;
    • Goffard, Jean-Christophe;
    • Savvides, Savvas N.;
    • Haerynck, Filomeen
    Publication type:
    Article
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    The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome.

    Published in:
    OncoImmunology, 2017, v. 6, n. 1, p. 1, doi. 10.1080/2162402X.2016.1253655
    By:
    • Pyfferoen, Lotte;
    • Brabants, Elisabeth;
    • Everaert, Celine;
    • De Cabooter, Nancy;
    • Heyns, Kelly;
    • Deswarte, Kim;
    • Vanheerswynghels, Manon;
    • De Prijck, Sofie;
    • Waegemans, Glenn;
    • Dullaers, Melissa;
    • Hammad, Hamida;
    • De Wever, Olivier;
    • Mestdagh, Pieter;
    • Vandesompele, Jo;
    • Lambrecht, Bart N.;
    • Vermaelen, Karim Y.
    Publication type:
    Article
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    A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes.

    Published in:
    Cytometry. Part A, 2016, v. 89, n. 1, p. 16, doi. 10.1002/cyto.a.22732
    By:
    • Aghaeepour, Nima;
    • Chattopadhyay, Pratip;
    • Chikina, Maria;
    • Dhaene, Tom;
    • Van Gassen, Sofie;
    • Kursa, Miron;
    • Lambrecht, Bart N.;
    • Malek, Mehrnoush;
    • McLachlan, G. J.;
    • Qian, Yu;
    • Qiu, Peng;
    • Saeys, Yvan;
    • Stanton, Rick;
    • Tong, Dong;
    • Vens, Celine;
    • Walkowiak, Sławomir;
    • Wang, Kui;
    • Finak, Greg;
    • Gottardo, Raphael;
    • Mosmann, Tim
    Publication type:
    Article
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    Corrigendum: Sterilizing Immunity against SARS‐CoV‐2 Infection in Mice by a Single‐Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist‐Adjuvanted Recombinant Spike Protein Vaccine.

    Published in:
    Angewandte Chemie International Edition, 2021, v. 60, n. 31, p. 16741, doi. 10.1002/anie.202105635
    By:
    • Jangra, Sonia;
    • De Vrieze, Jana;
    • Choi, Angela;
    • Rathnasinghe, Raveen;
    • Laghlali, Gabriel;
    • Uvyn, Annemiek;
    • Van Herck, Simon;
    • Nuhn, Lutz;
    • Deswarte, Kim;
    • Zhong, Zifu;
    • Sanders, Niek N.;
    • Lienenklaus, Stefan;
    • David, Sunil A.;
    • Strohmeier, Shirin;
    • Amanat, Fatima;
    • Krammer, Florian;
    • Hammad, Hamida;
    • Lambrecht, Bart N.;
    • Coughlan, Lynda;
    • García‐Sastre, Adolfo
    Publication type:
    Article
    46

    Sterilizing Immunity against SARS‐CoV‐2 Infection in Mice by a Single‐Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist‐Adjuvanted Recombinant Spike Protein Vaccine.

    Published in:
    Angewandte Chemie International Edition, 2021, v. 60, n. 17, p. 9467, doi. 10.1002/anie.202015362
    By:
    • Jangra, Sonia;
    • De Vrieze, Jana;
    • Choi, Angela;
    • Rathnasinghe, Raveen;
    • Laghlali, Gabriel;
    • Uvyn, Annemiek;
    • Van Herck, Simon;
    • Nuhn, Lutz;
    • Deswarte, Kim;
    • Zhong, Zifu;
    • Sanders, Niek N.;
    • Lienenklaus, Stefan;
    • David, Sunil A.;
    • Strohmeier, Shirin;
    • Amanat, Fatima;
    • Krammer, Florian;
    • Hammad, Hamida;
    • Lambrecht, Bart N.;
    • Coughlan, Lynda;
    • García‐Sastre, Adolfo
    Publication type:
    Article
    47

    Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer–Lipid Amphiphile Conjugates of Small‐Molecule TLR7/8 Agonists.

    Published in:
    Angewandte Chemie International Edition, 2019, v. 58, n. 43, p. 15390, doi. 10.1002/anie.201905687
    By:
    • De Vrieze, Jana;
    • Louage, Benoit;
    • Deswarte, Kim;
    • Zhong, Zifu;
    • De Coen, Ruben;
    • Van Herck, Simon;
    • Nuhn, Lutz;
    • Kaas Frich, Camilla;
    • Zelikin, Alexander N.;
    • Lienenklaus, Stefan;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • David, Sunil A.;
    • De Geest, Bruno G.
    Publication type:
    Article
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