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The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-021-01285-5
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- Article
Study of Estrogen Receptor-α and Receptor-β Gene Polymorphisms on Alzheimer's Disease.
- Published in:
- Journal of Alzheimer's Disease, 2011, v. 26, n. 3, p. 431, doi. 10.3233/JAD-2011-110362
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- Publication type:
- Article
The CALHM1 P86L Polymorphism is a Genetic Modifier of Age at Onset in Alzheimer's Disease: a Meta-Analysis Study.
- Published in:
- Journal of Alzheimer's Disease, 2010, v. 22, n. 1, p. 247, doi. 10.3233/JAD-2010-100933
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- Article
Is the Urea Cycle Involved in Alzheimer's Disease?
- Published in:
- Journal of Alzheimer's Disease, 2010, v. 21, n. 3, p. 1013, doi. 10.3233/JAD-2010-100630
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- Publication type:
- Article
Implication of the Immune System in Alzheimer's Disease: Evidence from Genome-Wide Pathway Analysis.
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- Journal of Alzheimer's Disease, 2010, v. 20, n. 4, p. 1107, doi. 10.3233/JAD-2010-100018
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- Publication type:
- Article
Common polygenic variation enhances risk prediction for Alzheimer's disease.
- Published in:
- 2015
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- Publication type:
- journal article
Association of MGMT and BIN1 genes with Alzheimer's disease risk across sex and APOE ε4 status.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2282, doi. 10.1002/alz.13550
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- Publication type:
- Article
Head‐to‐head comparison of aptamer‐ and antibody‐based proteomic platforms in CSF samples of a real‐world large cohort of a memory clinic.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082299
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- Publication type:
- Article
Screening Alzheimer's genetic risk factors against amyloid‐βeta synaptotoxicity.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076297
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- Publication type:
- Article
Analysis of Alzheimer's disease‐related synaptic alterations using microfluidic microglia/neuron co‐cultures.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074852
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- Publication type:
- Article
Screening tyrosine kinases for their involvement in synaptotoxicity induced by tau microtubule‐binding region fibrils.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074854
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- Publication type:
- Article
FERMT2 cleavage impacts APP metabolism in a Src‐dependent manner.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073037
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- Publication type:
- Article
APP‐dependent cell adhesion is regulated by GWAS genes.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076644
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- Publication type:
- Article
APP‐dependent cell adhesion is regulated by GWAS genes.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076644
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- Publication type:
- Article
Genetic propensity for cerebral amyloidosis and risk of mild cognitive impairment and Alzheimer's disease within a cognitive reserve framework.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 9, p. 3794, doi. 10.1002/alz.12980
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- Publication type:
- Article
Cell‐autonomous role of the AD susceptibility gene BIN1 in the regulation of hiPSC‐derived neurons network activity.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.062236
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- Publication type:
- Article
An enrichment of rare variants and the lysosomal pathways are important contributors to early onset Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055341
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- Publication type:
- Article
Role of the late‐onset Alzheimer's disease risk genes bin1 and ptk2b in the hyperexcitability of hiPSC‐derived neurons.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053632
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- Publication type:
- Article
High‐content screening of Alzheimer's disease genetic risk factors based on synaptic density analysis.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058660
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- Publication type:
- Article
Development of a fast and versatile method for genome‐wide association studies of longitudinal data: Genetics/endophenotypes.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042441
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- Publication type:
- Article
Alzheimer's genetic risk factor FERMT2 (kindlin‐2) controls axonal growth and synaptic plasticity in an APP‐dependent manner: Genetics: Genetics and omics of AD II.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041966
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- Publication type:
- Article
Isoform‐dependent neurotoxicity of the Alzheimer disease risk factor BIN1: Molecular and cell biology/endosomal‐lysosomal dysfunction.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039402
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- Publication type:
- Article
Differential transcript usage unravels transcriptional alterations in Alzheimer's disease human brains: Genetics/omics and systems biology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038695
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- Publication type:
- Article
Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.
- Published in:
- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03287-y
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- Publication type:
- Article
Genome-wide pathway analysis implicates intracellular transmembrane protein transport in Alzheimer disease.
- Published in:
- Journal of Human Genetics, 2010, v. 55, n. 10, p. 707, doi. 10.1038/jhg.2010.92
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- Publication type:
- Article
Structural Basis of Tau Interaction With BIN1 and Regulation by Tau Phosphorylation.
- Published in:
- Frontiers in Molecular Neuroscience, 2018, p. N.PAG, doi. 10.3389/fnmol.2018.00421
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- Publication type:
- Article
ISOFORM-DEPENDENT NEUROTOXICITY OF THE ALZHEIMER DISEASE RISK FACTOR BIN1 IN DROSOPHILA.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P972, doi. 10.1016/j.jalz.2017.06.1309
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- Publication type:
- Article
ALZHEIMER'S DISEASE SEQUENCING PROJECT: CASE-CONTROL ANALYSES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P570, doi. 10.1016/j.jalz.2017.07.186
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- Publication type:
- Article
PLASMA AMYLOID β PEPTIDE LEVELS AND RISK OF INCIDENT ALZHEIMER’S DISEASE AND DEMENTIA: UPDATE, REANALYSIS AND META-ANALYSIS OF INDIVIDUAL PARTICIPANTS’ DATA.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1516, doi. 10.1016/j.jalz.2017.07.637
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- Publication type:
- Article
EXPERIMENTAL IN VIVO EVIDENCE FOR TAU-INDUCED ANEUPLOIDY GENERATED DURING BRAIN DEVELOPMENT IN TAUOPATHIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1292, doi. 10.1016/j.jalz.2017.06.1954
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- Publication type:
- Article
A COMMON ALLELE IN SPI1 LOWERS RISK AND DELAYS AGE AT ONSET FOR ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P253, doi. 10.1016/j.jalz.2016.06.453
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- Publication type:
- Article
SECONDARY ANALYSES OF INTERNATIONAL GENOMICS OF ALZHEIMER'S PROJECT STAGE I GWAS SUMMARY DATA IDENTIFIES ADDITIONAL VARIANTS ASSOCIATED WITH LATE-ONSET ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P856, doi. 10.1016/j.jalz.2016.06.1755
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- Publication type:
- Article
Hcs genome-wide sirna screening identifies new modulators of app metabolism among the genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P327, doi. 10.1016/j.jalz.2015.07.475
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- Publication type:
- Article
Genetic risk factors of Alzheimer's disease and app metabolism.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P163, doi. 10.1016/j.jalz.2015.07.104
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- Publication type:
- Article
Plasma β-amyloid 40 levels are positively associated with mortality risks in the elderly.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 6, p. 672, doi. 10.1016/j.jalz.2014.04.515
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- Publication type:
- Article
Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 3, p. 249, doi. 10.1016/j.jalz.2014.07.001
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- Publication type:
- Article
Molecular characterisation of bridging integrator 1 (BIN1) interaction with tau.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P794, doi. 10.1016/j.jalz.2014.05.1546
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- Publication type:
- Article
Genetic complexity in the BIN1 locus
- Published in:
- 2012
- By:
- Publication type:
- Abstract
Bridging integrator 1 (BIN1) as a new partner of Tau?
- Published in:
- 2012
- By:
- Publication type:
- Abstract
Post-GWAS era: BIN1 as a proof of concept
- Published in:
- 2012
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- Publication type:
- Abstract
Meta-Analysis of Rare CLU Variants Shows Association With Alzheimer's Risk and Calls Attention To The CLU Beta-Subunit
- Published in:
- 2011
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- Publication type:
- Abstract
Assessment of BIN1 involvement in the Alzheimer's Disease pathophysiological process
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Risk For Alzheimer's Associated With A Copy Number Variation In The Complement Receptor 1 Increasing C3b/C4b Binding Sites
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Association of the APOE -219 Polymorphism with Alzheimer’s Disease: The Prospective Three City Study
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Genome-wide association studies using prospective cohorts: The CHARGE consortium
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Genome-wide association studies: The EADI consortium
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Association between IgM antibodies to herpes simplex virus and plasma amyloid-beta levels
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Characterization of a new ADAM as a key player of the APP metabolism
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Association of plasma Amyloid Beta peptides with blood pressure in the elderly
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Involvement of IL-33 in Alzheimer's disease
- Published in:
- 2011
- By:
- Publication type:
- Abstract