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Loss of Inpp5d has disease‐relevant and sex‐specific effects on glial transcriptomes.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5311, doi. 10.1002/alz.13901
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- Publication type:
- Article
Atherosclerotic Lesions and Mitochondria DNA Deletions in Brain Microvessels as a Central Target for the Development of Human AD and AD-Like Pathology in Aged Transgenic Mice.
- Published in:
- Annals of the New York Academy of Sciences, 2002, v. 977, n. 1, p. 45, doi. 10.1111/j.1749-6632.2002.tb04798.x
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- Publication type:
- Article
Triggering receptor expressed on myeloid cells 2 deficiency exacerbates injury-induced inflammation in a mouse model of tauopathy.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.978423
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- Publication type:
- Article
Dementia exacerbates periodontal bone loss in females.
- Published in:
- Journal of Periodontal Research, 2024, v. 59, n. 3, p. 512, doi. 10.1111/jre.13227
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- Publication type:
- Article
Loss of Interleukin Receptor-Associated Kinase 4 Signaling Suppresses Amyloid Pathology and Alters Microglial Phenotype in a Mouse Model of Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2012, v. 32, n. 43, p. 15112, doi. 10.1523/JNEUROSCI.1729-12.2012
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- Publication type:
- Article
The Cleavage Products of Amyloid-βPrecursor Protein Are Sorted to Distinct Carrier Vesicles That Are Independently Transported within Neurites.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 11, p. 3565, doi. 10.1523/JNEUROSCI.2558-08.2009
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- Publication type:
- Article
A β Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 43, p. 10786, doi. 10.1523/JNEUROSCI.2441-08.2008
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- Publication type:
- Article
The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice.
- Published in:
- FASEB Journal, 2012, v. 26, n. 7, p. 2899, doi. 10.1096/fj.12-205542
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- Publication type:
- Article
Effects of γ-secretase cleavage-region mutations on APP processing and Aβ formation: interpretation with sequential cleavage and α-helical model.
- Published in:
- Journal of Neurochemistry, 2008, v. 107, n. 3, p. 722, doi. 10.1111/j.1471-4159.2008.05643.x
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- Publication type:
- Article
Ccr2 deletion dissociates cavity size and tau pathology after mild traumatic brain injury.
- Published in:
- 2015
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- Publication type:
- journal article
The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.
- Published in:
- Nature, 2005, v. 435, n. 7040, p. 360, doi. 10.1038/nature03595
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- Publication type:
- Article
Independent effects of APOE on cholesterol metabolism and brain Aβ levels in an Alzheimer disease mouse model.
- Published in:
- Human Molecular Genetics, 2004, v. 13, n. 17, p. 1959, doi. 10.1093/hmg/ddh199
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- Publication type:
- Article
Genetic background regulates β-amyloid precursor protein processing and β-amyloid deposition in the mouse.
- Published in:
- Human Molecular Genetics, 2003, v. 12, n. 22, p. 2949, doi. 10.1093/hmg/ddg322
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- Publication type:
- Article
Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology.
- Published in:
- Alzheimer's Research & Therapy, 2016, v. 8, p. 1, doi. 10.1186/s13195-016-0221-y
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- Publication type:
- Article
Right sizing funding for Alzheimer's disease.
- Published in:
- 2011
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- Publication type:
- Editorial
An evolutionary driver of interspersed segmental duplications in primates.
- Published in:
- Genome Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s13059-020-02074-4
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- Publication type:
- Article
The Protein Kinase Double-Stranded RNA-Dependent (PKR) Enhances Protection against Disease Cause by a Non-Viral Pathogen.
- Published in:
- PLoS Pathogens, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.ppat.1003557
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- Publication type:
- Article
The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain.
- Published in:
- Acta Neuropathologica, 2012, v. 123, n. 1, p. 31, doi. 10.1007/s00401-011-0912-1
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- Publication type:
- Article
Inflammatory pathway analytes predicting rapid cognitive decline in MCI stage of Alzheimer's disease.
- Published in:
- Annals of Clinical & Translational Neurology, 2020, v. 7, n. 7, p. 1225, doi. 10.1002/acn3.51109
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- Publication type:
- Article
Key inflammatory pathway activations in the MCI stage of Alzheimer's disease.
- Published in:
- Annals of Clinical & Translational Neurology, 2019, v. 6, n. 7, p. 1248, doi. 10.1002/acn3.50827
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- Publication type:
- Article
TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation.
- Published in:
- Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01160-z
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- Publication type:
- Article
PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer's disease.
- Published in:
- Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01022-0
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- Publication type:
- Article
TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.
- Published in:
- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0216-6
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- Publication type:
- Article
The roles of fractalkine signaling in neurodegenerative disease.
- Published in:
- 2012
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- Publication type:
- Abstract
The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events.
- Published in:
- Molecular Neurodegeneration, 2009, v. 4, p. 1, doi. 10.1186/1750-1326-4-14
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- Publication type:
- Article
Translational animal models for Alzheimer's disease: An Alzheimer's Association Business Consortium Think Tank.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12114
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- Publication type:
- Article
Model organism development and evaluation for late‐onset Alzheimer's disease: MODEL‐AD.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12110
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- Publication type:
- Article
Improving preclinical to clinical translation in Alzheimer's disease research.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12038
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- Publication type:
- Article
Inflammation as a central mechanism in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2018, v. 4, n. 1, p. 575, doi. 10.1016/j.trci.2018.06.014
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- Publication type:
- Article
Loss of tau rescues inflammation-mediated neurodegeneration.
- Published in:
- Frontiers in Cellular Neuroscience, 2015, p. 1, doi. 10.3389/fnins.2015.00196
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- Publication type:
- Article
2021 Annual Reports of SECTIONS AND DIVISIONS of The Florida Bar.
- Published in:
- Florida Bar Journal, 2021, v. 95, n. 3, p. 56
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- Publication type:
- Article
Unlicensed Practice of Law.
- Published in:
- Florida Bar Journal, 2009, v. 83, n. 6, p. 76
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- Publication type:
- Article
Unlicensed Practice of Law.
- Published in:
- Florida Bar Journal, 2007, v. 81, n. 6, p. 61
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- Publication type:
- Article
Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2017, v. 37, n. 3, p. 637, doi. 10.1523/JNEUROSCI.2110-16.2017
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- Publication type:
- Article
Nuclear Receptors License Phagocytosis by Trem2<sup>+</sup> Myeloid Cells in Mouse Models of Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2015, p. 6532, doi. 10.1523/JNEUROSCI.4586-14.2015
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- Publication type:
- Article
Opposing Effects of Membrane-Anchored CX3CL1 on Amyloid and Tau Pathologies via the p38 MAPK Pathway.
- Published in:
- Journal of Neuroscience, 2014, v. 34, n. 37, p. 12538, doi. 10.1523/JNEUROSCI.0853-14.2014
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- Publication type:
- Article
N‐of‐1‐pathways transcriptomic analysis reveals distinct subtypes of Alzheimer's disease: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046575
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- Publication type:
- Article
Deep phenotyping of the 5XFAD model: IU/JAX/PITT MODEL‐AD center: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045981
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- Publication type:
- Article
Transcriptomic profiling of APOE4/Trem2*R47H mouse models for late‐onset Alzheimer's disease: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045390
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- Publication type:
- Article
Hallmarks of late‐onset Alzheimer's disease in a humanized mouse model: Development of new models and analysis methods/screening studies/platforms.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045162
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- Publication type:
- Article
Identification and characterization of immune‐focused therapeutic targets in the MODEL‐AD and TREAT‐AD consortia: Microbiome in Alzheimer's disease: Pathogenesis and treatment implications.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044157
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- Publication type:
- Article
In vivo testing of the role of Alzheimer's disease coding variants: Functionalizing genetic variants in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043896
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- Publication type:
- Article
Neurovascular uncoupling of cerebral blood flow and glucose metabolism in APOE4, TREM2, and APOE4.TREM2 mice: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041531
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- Publication type:
- Article
Pharmacokinetic, pharmacodynamic and transcriptomic analyses of verubecestat treatment in 5XFAD mice: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041491
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- Publication type:
- Article
The IUSM‐Purdue Alzheimer's Disease Drug Discovery Center: A member of the NIH‐funded TREAT‐AD consortium: Nonhuman/Novel screening strategies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041107
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- Publication type:
- Article
Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 7, p. 1095, doi. 10.1002/alz.12059
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- Publication type:
- Article
P4‐098: TRANSCRIPTOMIC ALTERATIONS DRIVEN BY THE TREM2*R47H ALLELE VARY ACROSS DIFFERENT TRANSGENIC MOUSE MODELS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1312, doi. 10.1016/j.jalz.2019.06.3758
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- Publication type:
- Article
P4‐091: THE TREM2*R47H VARIANT ALTERS EXPRESSION AND FUNCTION IN MOUSE MODELS OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1309, doi. 10.1016/j.jalz.2019.06.3751
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- Publication type:
- Article
P4‐079: CRITICAL EVALUATION OF THE PHARMACOKINETICS OF VERUBECESTAT IN AGED 5XFAD MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1304, doi. 10.1016/j.jalz.2019.06.3739
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- Publication type:
- Article
P2‐260: BLOOD BIOMARKERS FOR MEMORY: TOWARDS EARLY DETECTION OF RISK FOR ALZHEIMER DISEASE, PHARMACOGENOMICS, AND REPURPOSED DRUGS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P684, doi. 10.1016/j.jalz.2019.06.2667
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- Publication type:
- Article