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Loss of PIKfyve drives the spongiform degeneration in prion diseases.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 9, p. 1, doi. 10.15252/emmm.202114714
By:
- Lakkaraju, Asvin K K;
- Frontzek, Karl;
- Lemes, Emina;
- Herrmann, Uli;
- Losa, Marco;
- Marpakwar, Rajlakshmi;
- Aguzzi, Adriano
Publication type:
Article
Hyaline Fibromatosis Syndrome inducing mutations in the ectodomain of anthrax toxin receptor 2 can be rescued by proteasome inhibitors.
Published in:
EMBO Molecular Medicine, 2011, v. 3, n. 4, p. 208, doi. 10.1002/emmm.201100124
By:
- Deuquet, Julie;
- Lausch, Ekkehart;
- Guex, Nicolas;
- Abrami, Laurence;
- Salvi, Suzanne;
- Lakkaraju, Asvin;
- Ramirez, Maria Celeste M.;
- Martignetti, John A.;
- Rokicki, Dariusz;
- Bonafe, Luisa;
- Superti-Furga, Andrea;
- van der Goot, Françoise G.
Publication type:
Article
An arrayed genome‐wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate‐limiting for prion propagation.
Published in:
EMBO Journal, 2022, v. 41, n. 23, p. 1, doi. 10.15252/embj.2022112338
By:
- Avar, Merve;
- Heinzer, Daniel;
- Thackray, Alana M;
- Liu, Yingjun;
- Hruska‐Plochan, Marian;
- Sellitto, Stefano;
- Schaper, Elke;
- Pease, Daniel P;
- Yin, Jiang‐An;
- Lakkaraju, Asvin KK;
- Emmenegger, Marc;
- Losa, Marco;
- Chincisan, Andra;
- Hornemann, Simone;
- Polymenidou, Magdalini;
- Bujdoso, Raymond;
- Aguzzi, Adriano
Publication type:
Article
Neurodegeneration and Unfolded-Protein Response in Mice Expressing a Membrane-Tethered Flexible Tail of PrP.
Published in:
PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0117412
By:
- Dametto, Paolo;
- Lakkaraju, Asvin K. K.;
- Bridel, Claire;
- Villiger, Lukas;
- O’Connor, Tracy;
- Herrmann, Uli S.;
- Pelczar, Pawel;
- Rülicke, Thomas;
- McHugh, Donal;
- Adili, Arlind;
- Aguzzi, Adriano
Publication type:
Article
Soluble dimeric prion protein ligand activates Adgrg6 receptor but does not rescue early signs of demyelination in PrP-deficient mice.
Published in:
PLoS ONE, 2020, v. 15, n. 11, p. 1, doi. 10.1371/journal.pone.0242137
By:
- Henzi, Anna;
- Senatore, Assunta;
- Lakkaraju, Asvin K. K.;
- Scheckel, Claudia;
- Mühle, Jonas;
- Reimann, Regina;
- Sorce, Silvia;
- Schertler, Gebhard;
- Toyka, Klaus V.;
- Aguzzi, Adriano
Publication type:
Article
Palmitoylated calnexin is a key component of the ribosome-translocon complex.
Published in:
EMBO Journal, 2012, v. 31, n. 7, p. 1823, doi. 10.1038/emboj.2012.15
By:
- Lakkaraju, Asvin KK;
- Abrami, Laurence;
- Lemmin, Thomas;
- Blaskovic, Sanja;
- Kunz, Béatrice;
- Kihara, Akio;
- Dal Peraro, Matteo;
- van der Goot, Françoise Gisou
Publication type:
Article
Glial activation in prion diseases is selectively triggered by neuronal PrP<sup>Sc</sup>.
Published in:
Brain Pathology, 2022, v. 32, n. 5, p. 1, doi. 10.1111/bpa.13056
By:
- Lakkaraju, Asvin K. K.;
- Sorce, Silvia;
- Senatore, Assunta;
- Nuvolone, Mario;
- Guo, Jingjing;
- Schwarz, Petra;
- Moos, Rita;
- Pelczar, Pawel;
- Aguzzi, Adriano
Publication type:
Article
Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity.
Published in:
PLoS Pathogens, 2017, v. 13, n. 11, p. 1, doi. 10.1371/journal.ppat.1006733
By:
- Goniotaki, Despoina;
- Lakkaraju, Asvin K. K.;
- Shrivastava, Amulya N.;
- Bakirci, Pamela;
- Sorce, Silvia;
- Senatore, Assunta;
- Marpakwar, Rajlakshmi;
- Hornemann, Simone;
- Gasparini, Fabrizio;
- Triller, Antoine;
- Aguzzi, Adriano
Publication type:
Article
Characterization of APOBEC3G binding to 7SL RNA.
Published in:
Retrovirology, 2008, v. 5, p. 1, doi. 10.1186/1742-4690-5-54
By:
- Bach, Daniel;
- Peddi, Shyam;
- Mangeat, Bastien;
- Lakkaraju, Asvin;
- Strub, Katharina;
- Trono, Didier
Publication type:
Article

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