Works by Laitinen, Jarmo T.

Results: 33

The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D–lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections.

Published in:

British Journal of Pharmacology, 2006, v. 147, n. 6, p. 596, doi. 10.1038/sj.bjp.0706671

By:

Palomäki, Ville A. B.;
Laitinen, Jarmo T.

Publication type:

Article

The ‘allosteric modulator’ SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.

Published in:

British Journal of Pharmacology, 2006, v. 147, n. 4, p. 422, doi. 10.1038/sj.bjp.0706624

By:

Lewandowicz, Anna M.;
Vepsäläinen, Jouko;
Laitinen, Jarmo T.

Publication type:

Article

Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor.

Published in:

2005

By:

Savinainen, Juha R.;
Kokkola, Tarja;
Salo, Outi M. H.;
Poso, Antti;
Järvinen, Tomi;
Laitinen, Jarmo T.;
Järvinen, Tomi

Publication type:

journal article

An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors.

Published in:

2003

By:

Savinainen, Juha R.;
Saario, Susanna M.;
Niemi, Riku;
Jarvinen, Tomi;
Laitinen, Jarmo T.;
Järvinen, Tomi

Publication type:

journal article

Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes.

Published in:

2001

By:

Savinainen, Juha R;
Järvinen, Tomi;
Laine, Krista;
Laitinen, Jarmo T;
Savinainen, J R;
Järvinen, T;
Laine, K;
Laitinen, J T

Publication type:

journal article

Characterization of Melatonin Receptors in the Rat Area postrema: Modulation of Affinity with Cations and Guanine Nucleotides.

Published in:

Neuroendocrinology, 1990, v. 51, n. 6, p. 619, doi. 10.1159/000125401

By:

Laitinen, Jarmo T.;
Flügge, Gabriella;
Saavedra, Juan M.

Publication type:

Article

Differential Expression of Melatonin Receptors in Spontaneously Hypertensive Rats.

Published in:

Neuroendocrinology, 1992, v. 56, n. 6, p. 864, doi. 10.1159/000126318

By:

Viswanathan, Mohan;
Laitinen, Jarmo T.;
Saavedra, Juan M.

Publication type:

Article

Pineal Muscarinic Phosphoinositide Responses: Age-Associated Sensitization, Agonist-Induced Desensitization and Increase in Melatonin Release from Cultured Pineal Glands.

Published in:

Neuroendocrinology, 1992, v. 55, n. 5, p. 492, doi. 10.1159/000126162

By:

Laitinen, Jarmo T.;
Vakkuri, Olli;
Saavedra, Juan M.

Publication type:

Article

Hormonal regulation of Gαi2 and mPRα in immortalized human oviductal cell line OE-E6/E7.

Published in:

Molecular Human Reproduction, 2007, v. 13, n. 12, p. 845, doi. 10.1093/molehr/gam075

By:

Mönkkönen, Kati S.;
Aflatoonian, Reza;
Lee, Kai-Fai;
Yeung, William S.B.;
Tsao, Sai-Wah;
Laitinen, Jarmo T.;
Fazeli, Alireza

Publication type:

Article

Long-term Induction of Haem Oxygenase-1 (HSP-32) in Astrocytes and Microglia Following Transient Focal Brain Ischaemia in the Rat.

Published in:

European Journal of Neuroscience, 1996, v. 8, n. 11, p. 2265, doi. 10.1111/j.1460-9568.1996.tb01190.x

By:

Koistinaho, Jari;
Miettinen, Susanna;
Keinänen, Riitta;
Vartiainen, Nina;
Roivainen, Reina;
Laitinen, Jarmo T.

Publication type:

Article

Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA1 receptor signalling in rat brain cryosections without affecting global LPA degradation.

Published in:

BMC Pharmacology, 2012, v. 12, n. 1, p. 7, doi. 10.1186/1471-2210-12-7

By:

Aaltonen, Niina;
Lehtonen, Marko;
Varonen, Katri;
Arrufat Goterris, Gemma;
Laitinen, Jarmo T.

Publication type:

Article

Optimization of 1,2,5-Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 253, doi. 10.1002/cmdc.201402453

By:

Patel, Jayendra Z.;
Nevalainen, Tapio J.;
Savinainen, Juha R.;
Adams, Yahaya;
Laitinen, Tuomo;
Runyon, Robert S.;
Vaara, Miia;
Ahenkorah, Stephen;
Kaczor, Agnieszka A.;
Navia‐Paldanius, Dina;
Gynther, Mikko;
Aaltonen, Niina;
Joharapurkar, Amit A.;
Jain, Mukul R.;
Haka, Abigail S.;
Maxfield, Frederick R.;
Laitinen, Jarmo T.;
Parkkari, Teija

Publication type:

Article

Screening of Various Hormone-Sensitive Lipase Inhibitors as Endocannabinoid-Hydrolyzing Enzyme Inhibitors.

Published in:

ChemMedChem, 2009, v. 4, n. 8, p. 1253, doi. 10.1002/cmdc.200900137

By:

Minkkilä, Anna;
Savinainen, Juha R.;
Käsnänen, Heikki;
Xhaard, Henri;
Nevalainen, Tapio;
Laitinen, Jarmo T.;
Poso, Antti;
Leppänen, Jukka;
Saario, Susanna M.

Publication type:

Article

[[sup 35]S]GTPgammaS autoradiography reveals a wide distribution of G[sub i/o]-linked ADP....

Published in:

Journal of Neurochemistry, 2001, v. 77, n. 2, p. 505, doi. 10.1046/j.1471-4159.2001.00265.x

By:

Laitinen, Jarmo T.;
Uri, Asko;
Raidaru, Gerda;
Miettinen, Riita

Publication type:

Article

Protective Properties of Tin- and Manganese-Centered Porphyrins Against Hydrogen Peroxide-Mediated Injury in Rat Astroglial Cells.

Published in:

Journal of Neurochemistry, 1998, v. 71, n. 6, p. 2497, doi. 10.1046/j.1471-4159.1998.71062497.x

By:

Dwyer, Barney E.;
Lu, Shi-Yi;
Laitinen, Jarmo T.;
Nishimura, Robert N.

Publication type:

Article

Guanosine 5′-(γ-[35S]Thio)triphosphate Autoradiography Allows Selective Detection of Histamine H3 Receptor-Dependent G Protein Activation in Rat Brain Tissue Sections.

Published in:

Journal of Neurochemistry, 1998, v. 71, n. 2, p. 808, doi. 10.1046/j.1471-4159.1998.71020808.x

By:

Laitinen, Jarmo T.;
Jokinen, Marianne

Publication type:

Article

Dopamine Stimulates K+ Efflux in the Chick Retina via D1 Receptors Independently of Adenylyl Cyclase Activation.

Published in:

Journal of Neurochemistry, 1993, v. 61, n. 4, p. 1461, doi. 10.1111/j.1471-4159.1993.tb13641.x

By:

Laitinen, Jarmo T.

Publication type:

Article

Differential Sensitivity to Cations of the Melatonin Receptors in the Rat Area Postrema and Suprachiasmatic Nuclei.

Published in:

Journal of Neurochemistry, 1990, v. 55, n. 4, p. 1450, doi. 10.1111/j.1471-4159.1990.tb03161.x

By:

Laitinen, Jarmo T.;
Saavedra, Juan M.

Publication type:

Article

Intracerebroventricular antisense knockdown of Gαi2 results in ciliary stasis and ventricular dilatation in the rat.

Published in:

BMC Neuroscience, 2007, v. 8, p. 1, doi. 10.1186/1471-2202-8-26

By:

Mönkkönen, Kati S.;
Hakumäki, Juhana M.;
Hirst, Robert A.;
Miettinen, Riitta A.;
O'Callaghan, Christopher;
Männistö, Pekka T.;
Laitinen, Jarmo T.

Publication type:

Article

Visualization of 2-arachidonoylglycerol accumulation and cannabinoid CB1 receptor activity in rat brain cryosections by functional autoradiography.

Published in:

Journal of Neurochemistry, 2007, v. 101, n. 4, p. 972, doi. 10.1111/j.1471-4159.2006.04403.x

By:

Palomäki, Ville A. B.;
Lehtonen, Marko;
Savinainen, Juha R.;
Laitinen, Jarmo T.

Publication type:

Article

Localization and variable expression of G{alpha}i2 in human endometrium and Fallopian tubes.

Published in:

Human Reproduction, 2007, v. 22, n. 5, p. 1224

By:

Kati S. Mönkkönen;
Reza Aflatoonian;
Kai-Fai Lee;
William S.B. Yeung;
Sai-Wah Tsao;
Jarmo T. Laitinen;
Elizabeth M. Tuckerman;
T.C. Li;
Alireza Fazeli

Publication type:

Article

Monoglyceride Lipase as an Enzyme Hydrolyzing 2-Arachidonoylglycerol.

Published in:

Chemistry & Biodiversity, 2007, v. 4, n. 8, p. 1903, doi. 10.1002/cbdv.200790158

By:

Saario, Susanna M.;
Laitinen, Jarmo T.

Publication type:

Article

Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.

Published in:

Journal of Pineal Research, 2007, v. 43, n. 3, p. 255, doi. 10.1111/j.1600-079X.2007.00470.x

By:

Kokkola, Tarja;
Vaittinen, Maija;
Laitinen, Jarmo T.

Publication type:

Article

The functional role of cysteines adjacent to the NRY motif of the human MT1 melatonin receptor.

Published in:

Journal of Pineal Research, 2005, v. 39, n. 1, p. 1, doi. 10.1111/j.1600-079X.2004.00204.x

By:

Kokkola, Tarja;
Salo, Outi M. H.;
Poso, Antti;
Laitinen, Jarmo T.

Publication type:

Article

Nocturnal 6-hydroxymelatonin sulfate excretion in female workers exposed to magnetic fields.

Published in:

Journal of Pineal Research, 2000, v. 28, n. 2, p. 97, doi. 10.1034/j.1600-079X.2001.280205.x

By:

Juutilainen, Jukka;
Stevens, Richard G.;
Anderson, Larry E.;
Hansen, Norman H.;
Kilpeläinen, Marko;
Kumlin, Timo;
Laitinen, Jarmo T.;
Sobel, Eugene;
Wilson, Bary W.

Publication type:

Article

Effects of melatonin implants on winter fur growth and testicular recrudescence in adult male raccoon dogs ( Nyctereutes procyonoides).

Published in:

Journal of Pineal Research, 1996, v. 20, n. 3, p. 148, doi. 10.1111/j.1600-079X.1996.tb00251.x

By:

Xiao, Yongjun;
Forsberg, Mats;
Laitinen, Jarmo T.;
Valtonen, Maija

Publication type:

Article

Different patterns of light exposure in relation to melatonin and Cortisol rhythms and sleep of night workers.

Published in:

Journal of Pineal Research, 1994, v. 16, n. 3, p. 127, doi. 10.1111/j.1600-079X.1994.tb00092.x

By:

Koller, Margit;
Härma, Mikko;
Laitinen, Jarmo T.;
Kundi, Michael;
Piegler, Brigitte;
Haider, Manfred

Publication type:

Article

Biochemical and Pharmacological Characterization of the Human Lymphocyte Antigen B-Associated Transcript 5 (BAT5/ABHD16A).

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109869

By:

Savinainen, Juha R.;
Patel, Jayendra Z.;
Parkkari, Teija;
Navia-Paldanius, Dina;
Marjamaa, Joona J. T.;
Laitinen, Tuomo;
Nevalainen, Tapio;
Laitinen, Jarmo T.

Publication type:

Article

Discovery of Triterpenoids as Reversible Inhibitors of α/β-hydrolase Domain Containing 12 (ABHD12).

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0098286

By:

Parkkari, Teija;
Haavikko, Raisa;
Laitinen, Tuomo;
Navia-Paldanius, Dina;
Rytilahti, Roosa;
Vaara, Miia;
Lehtonen, Marko;
Alakurtti, Sami;
Yli-Kauhaluoma, Jari;
Nevalainen, Tapio;
Savinainen, Juha R.;
Laitinen, Jarmo T.

Publication type:

Article

Therapeutic Potential of Endocannabinoid-Hydrolysing Enzyme Inhibitors.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2007, v. 101, n. 5, p. 287, doi. 10.1111/j.1742-7843.2007.00130.x

By:

Saario, Susanna M.;
Laitinen, Jarmo T.

Publication type:

Article

Melatonin receptor genes.

Published in:

Annals of Medicine, 1998, v. 30, n. 1, p. 88, doi. 10.3109/07853899808999389

By:

Kokkola, Tarja;
Laitinen, Jarmo T

Publication type:

Article

High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections – Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils.

Published in:

Biological Procedures Online, 2020, v. 22, n. 1, p. 1, doi. 10.1186/s12575-020-00118-4

By:

Aaltonen, Niina;
Singha, Prosanta K.;
Jakupović, Hermina;
Wirth, Thomas;
Samaranayake, Haritha;
Pasonen-Seppänen, Sanna;
Rilla, Kirsi;
Varjosalo, Markku;
Edgington-Mitchell, Laura E.;
Kasperkiewicz, Paulina;
Drag, Marcin;
Kälvälä, Sara;
Moisio, Eemeli;
Savinainen, Juha R.;
Laitinen, Jarmo T.

Publication type:

Article

S-Nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner.

Published in:

BMC Cell Biology, 2005, v. 6, p. 21, doi. 10.1186/1471-2121-6-21

By:

Kokkola, Tarja;
Savinainen, Juha R.;
Mönkkönen, Kati S.;
Retamal, Montse Durán;
Laitinen, Jarmo T.

Publication type:

Article

Works by Laitinen, Jarmo T.

The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D–lysophosphatidic acid receptor axis and 5-HT<sub>1A</sub> receptors in rat brain sections.

The ‘allosteric modulator’ SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.

Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor.

An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors.

Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes.

Characterization of Melatonin Receptors in the Rat Area postrema: Modulation of Affinity with Cations and Guanine Nucleotides.

Differential Expression of Melatonin Receptors in Spontaneously Hypertensive Rats.

Pineal Muscarinic Phosphoinositide Responses: Age-Associated Sensitization, Agonist-Induced Desensitization and Increase in Melatonin Release from Cultured Pineal Glands.

Hormonal regulation of Gαi2 and mPRα in immortalized human oviductal cell line OE-E6/E7.

Long-term Induction of Haem Oxygenase-1 (HSP-32) in Astrocytes and Microglia Following Transient Focal Brain Ischaemia in the Rat.

Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA<sub>1</sub> receptor signalling in rat brain cryosections without affecting global LPA degradation.

Optimization of 1,2,5-Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors.

Screening of Various Hormone-Sensitive Lipase Inhibitors as Endocannabinoid-Hydrolyzing Enzyme Inhibitors.

[[sup 35]S]GTPgammaS autoradiography reveals a wide distribution of G[sub i/o]-linked ADP....

Protective Properties of Tin- and Manganese-Centered Porphyrins Against Hydrogen Peroxide-Mediated Injury in Rat Astroglial Cells.

Guanosine 5′-(γ-[<sup>35</sup>S]Thio)triphosphate Autoradiography Allows Selective Detection of Histamine H<sub>3</sub> Receptor-Dependent G Protein Activation in Rat Brain Tissue Sections.

Dopamine Stimulates K<sup>+</sup> Efflux in the Chick Retina via D<sub>1</sub> Receptors Independently of Adenylyl Cyclase Activation.

Differential Sensitivity to Cations of the Melatonin Receptors in the Rat Area Postrema and Suprachiasmatic Nuclei.

Intracerebroventricular antisense knockdown of Gα<sub>i2</sub> results in ciliary stasis and ventricular dilatation in the rat.

Visualization of 2-arachidonoylglycerol accumulation and cannabinoid CB<sub>1</sub> receptor activity in rat brain cryosections by functional autoradiography.

Localization and variable expression of G{alpha}i2 in human endometrium and Fallopian tubes.

Monoglyceride Lipase as an Enzyme Hydrolyzing 2-Arachidonoylglycerol.

Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.

The functional role of cysteines adjacent to the NRY motif of the human MT1 melatonin receptor.

Nocturnal 6-hydroxymelatonin sulfate excretion in female workers exposed to magnetic fields.

Effects of melatonin implants on winter fur growth and testicular recrudescence in adult male raccoon dogs ( Nyctereutes procyonoides).

Different patterns of light exposure in relation to melatonin and Cortisol rhythms and sleep of night workers.

Biochemical and Pharmacological Characterization of the Human Lymphocyte Antigen B-Associated Transcript 5 (BAT5/ABHD16A).

Discovery of Triterpenoids as Reversible Inhibitors of α/β-hydrolase Domain Containing 12 (ABHD12).

Therapeutic Potential of Endocannabinoid-Hydrolysing Enzyme Inhibitors.

Melatonin receptor genes.

High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections – Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils.

S-Nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner.