Works by Laheru, Daniel A

Results: 54
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    A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39196-9
    By:
    • Heumann, Thatcher;
    • Judkins, Carol;
    • Li, Keyu;
    • Lim, Su Jin;
    • Hoare, Jessica;
    • Parkinson, Rose;
    • Cao, Haihui;
    • Zhang, Tengyi;
    • Gai, Jessica;
    • Celiker, Betul;
    • Zhu, Qingfeng;
    • McPhaul, Thomas;
    • Durham, Jennifer;
    • Purtell, Katrina;
    • Klein, Rachel;
    • Laheru, Daniel;
    • De Jesus-Acosta, Ana;
    • Le, Dung T.;
    • Narang, Amol;
    • Anders, Robert
    Publication type:
    Article
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    dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer.

    Published in:
    Cancer Biology & Therapy, 2014, v. 15, n. 6, p. 1, doi. 10.4161/cbt.28413
    By:
    • Mcallister, Florencia;
    • Pineda, Danielle M.;
    • Jimbo, Masaya;
    • Lal, Shruti;
    • Burkhart, Richard A.;
    • Moughan, Jennifer;
    • Winter, Kathryn A.;
    • Abdelmohsen, Kotb;
    • Gorospe, Myriam;
    • De Jesus Acosta, Ana;
    • Lankapalli, Rachana H.;
    • Winter, Jordan M.;
    • Yeo, Charles J.;
    • Witkiewicz, Agnieska K.;
    • Iacobuzio-Donahue, Christine A.;
    • Laheru, Daniel;
    • Brody, Jonathan R.
    Publication type:
    Article
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    Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma.

    Published in:
    2020
    By:
    • De Jesus-Acosta, Ana;
    • Sugar, Elizabeth A.;
    • O'Dwyer, Peter J.;
    • Ramanathan, Ramesh K.;
    • Von Hoff, Daniel D.;
    • Rasheed, Zeshaan;
    • Zheng, Lei;
    • Begum, Asma;
    • Anders, Robert;
    • Maitra, Anirban;
    • McAllister, Florencia;
    • Rajeshkumar, N. V.;
    • Yabuuchi, Shinichi;
    • de Wilde, Roeland F.;
    • Batukbhai, Bhavina;
    • Sahin, Ismet;
    • Laheru, Daniel A.
    Publication type:
    journal article
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    Phase I study of the safety, tolerability and pharmacokinetics of PHA-848125AC, a dual tropomyosin receptor kinase A and cyclin-dependent kinase inhibitor, in patients with advanced solid malignancies.

    Published in:
    Investigational New Drugs, 2012, v. 30, n. 6, p. 2334, doi. 10.1007/s10637-011-9774-6
    By:
    • Weiss, Glen;
    • Hidalgo, Manuel;
    • Borad, Mitesh;
    • Laheru, Daniel;
    • Tibes, Raoul;
    • Ramanathan, Ramesh;
    • Blaydorn, Lisa;
    • Jameson, Gayle;
    • Jimeno, Antonio;
    • Isaacs, Jeffrey;
    • Scaburri, Angela;
    • Pacciarini, Maria;
    • Fiorentini, Francesco;
    • Ciomei, Marina;
    • Hoff, Daniel
    Publication type:
    Article
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    Prognostic Significance of Tumorigenic Cells With Mesenchymal Features in Pancreatic Adenocarcinoma.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2010, v. 102, n. 5, p. 340, doi. 10.1093/jnci/djp535
    By:
    • Rasheed, Zeshaan A.;
    • Jie Yang;
    • Wang, Qiuju;
    • Kowalski, Jeanne;
    • Freed, Irwin;
    • Murter, Christopher;
    • Hong, Seung-Mo;
    • Koorstra, Jan-Bart;
    • Rajeshkumar, N. V.;
    • Xiaobing He;
    • Goggins, Michael;
    • Iacobuzio-Donahue, Christine;
    • Berman, David M.;
    • Laheru, Daniel;
    • Jimeno, Antonio;
    • Hidalgo, Manuel;
    • Maitra, Anirban;
    • Matsui, William
    Publication type:
    Article
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    Phase 2 multi-institutional trial evaluating gemcitabine and stereotactic body radiotherapy for patients with locally advanced unresectable pancreatic adenocarcinoma.

    Published in:
    Cancer (0008543X), 2015, v. 121, n. 7, p. 1128, doi. 10.1002/cncr.29161
    By:
    • Herman, Joseph M.;
    • Chang, Daniel T.;
    • Goodman, Karyn A.;
    • Dholakia, Avani S.;
    • Raman, Siva P.;
    • Hacker‐Prietz, Amy;
    • Iacobuzio‐Donahue, Christine A.;
    • Griffith, Mary E.;
    • Pawlik, Timothy M.;
    • Pai, Jonathan S.;
    • O'Reilly, Eileen;
    • Fisher, George A.;
    • Wild, Aaron T.;
    • Rosati, Lauren M.;
    • Zheng, Lei;
    • Wolfgang, Christopher L.;
    • Laheru, Daniel A.;
    • Columbo, Laurie A.;
    • Sugar, Elizabeth A.;
    • Koong, Albert C.
    Publication type:
    Article
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    A multi-institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer.

    Published in:
    Cancer (0008543X), 2013, v. 119, n. 15, p. 2692, doi. 10.1002/cncr.28117
    By:
    • Kim, Edward J.;
    • Ben‐Josef, Edgar;
    • Herman, Joseph M.;
    • Bekaii‐Saab, Tanios;
    • Dawson, Laura A.;
    • Griffith, Kent A.;
    • Francis, Isaac R.;
    • Greenson, Joel K.;
    • Simeone, Diane M.;
    • Lawrence, Theodore S.;
    • Laheru, Daniel;
    • Wolfgang, Christopher L.;
    • Williams, Terence;
    • Bloomston, Mark;
    • Moore, Malcolm J.;
    • Wei, Alice;
    • Zalupski, Mark M.
    Publication type:
    Article
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    Family history as a marker of platinum sensitivity in pancreatic adenocarcinoma.

    Published in:
    Cancer Chemotherapy & Pharmacology, 2015, v. 76, n. 3, p. 489, doi. 10.1007/s00280-015-2788-6
    By:
    • Fogelman, David;
    • Sugar, Elizabeth;
    • Oliver, George;
    • Shah, Neeraj;
    • Klein, Alison;
    • Alewine, Christine;
    • Wang, Huamin;
    • Javle, Milind;
    • Shroff, Rachna;
    • Wolff, Robert;
    • Abbruzzese, James;
    • Laheru, Daniel;
    • Diaz, Luis
    Publication type:
    Article
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    A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer.

    Published in:
    Cancer Medicine, 2020, v. 9, n. 4, p. 1485, doi. 10.1002/cam4.2763
    By:
    • Yarchoan, Mark;
    • Huang, Chiung‐Yu;
    • Zhu, Qingfeng;
    • Ferguson, Anna K.;
    • Durham, Jennifer N.;
    • Anders, Robert A.;
    • Thompson, Elizabeth D.;
    • Rozich, Noah S.;
    • Thomas, Dwayne L.;
    • Nauroth, Julie M.;
    • Rodriguez, Christina;
    • Osipov, Arsen;
    • De Jesus‐Acosta, Ana;
    • Le, Dung T.;
    • Murphy, Adrian G.;
    • Laheru, Daniel;
    • Donehower, Ross C.;
    • Jaffee, Elizabeth M.;
    • Zheng, Lei;
    • Azad, Nilofer S.
    Publication type:
    Article
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    Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer.

    Published in:
    Cancer Medicine, 2017, v. 6, n. 7, p. 1552, doi. 10.1002/cam4.1104
    By:
    • Shrestha, Bikram;
    • Sun, Yifei;
    • Faisal, Farzana;
    • Kim, Victoria;
    • Soares, Kevin;
    • Blair, Alex;
    • Herman, Joseph M.;
    • Narang, Amol;
    • Dholakia, Avani S.;
    • Rosati, Lauren;
    • Hacker‐Prietz, Amy;
    • Chen, Linda;
    • Laheru, Daniel A.;
    • De Jesus‐Acosta, Ana;
    • Le, Dung T.;
    • Donehower, Ross;
    • Azad, Nilofar;
    • Diaz, Luis A.;
    • Murphy, Adrian;
    • Lee, Valerie
    Publication type:
    Article
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    The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma.

    Published in:
    PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0180181
    By:
    • Begum, Asma;
    • Ewachiw, Theodore;
    • Jung, Clinton;
    • Huang, Ally;
    • Norberg, K. Jessica;
    • Marchionni, Luigi;
    • Mcmillan, Ross;
    • Penchev, Vesselin;
    • Rajeshkumar, N. V.;
    • Maitra, Anirban;
    • Wood, Laura;
    • Wang, Chenguang;
    • Wolfgang, Christopher;
    • Dejesus-Acosta, Ana;
    • Laheru, Daniel;
    • Shapiro, Irina M.;
    • Padval, Mahesh;
    • Pachter, Jonathan A.;
    • Weaver, David T.;
    • Rasheed, Zeshaan A.
    Publication type:
    Article
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    Neoadjuvant Stereotactic Body Radiotherapy After Upfront Chemotherapy Improves Pathologic Outcomes Compared With Chemotherapy Alone for Patients With Borderline Resectable or Locally Advanced Pancreatic Adenocarcinoma Without Increasing Perioperative Toxicity

    Published in:
    Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2022, v. 29, n. 4, p. 2456, doi. 10.1245/s10434-021-11202-8
    By:
    • Hill, Colin S.;
    • Rosati, Lauren M.;
    • Hu, Chen;
    • Fu, Wei;
    • Sehgal, Shuchi;
    • Hacker-Prietz, Amy;
    • Wolfgang, Christopher L.;
    • Weiss, Matthew J.;
    • Burkhart, Richard A.;
    • Hruban, Ralph H.;
    • De Jesus-Acosta, Ana;
    • Le, Dung T.;
    • Zheng, Lei;
    • Laheru, Daniel A.;
    • He, Jin;
    • Narang, Amol K.;
    • Herman, Joseph M.
    Publication type:
    Article
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    Anatomic Criteria Determine Resectability in Locally Advanced Pancreatic Cancer.

    Published in:
    Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2022, v. 29, n. 1, p. 401, doi. 10.1245/s10434-021-10663-1
    By:
    • Gemenetzis, Georgios;
    • Blair, Alex B.;
    • Nagai, Minako;
    • Groot, Vincent P.;
    • Ding, Ding;
    • Javed, Ammar A.;
    • Burkhart, Richard A.;
    • Fishman, Elliot K.;
    • Hruban, Ralph H.;
    • Weiss, Matthew J.;
    • Cameron, John L.;
    • Narang, Amol;
    • Laheru, Daniel;
    • Lafaro, Kelly;
    • Herman, Joseph M.;
    • Zheng, Lei;
    • Burns III, William R.;
    • Wolfgang, Christopher L.;
    • He, Jin
    Publication type:
    Article
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    Stereotactic Body Radiation Therapy for Isolated Local Recurrence After Surgical Resection of Pancreatic Ductal Adenocarcinoma Appears to be Safe and Effective.

    Published in:
    Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2018, v. 25, n. 1, p. 280, doi. 10.1245/s10434-017-6134-6
    By:
    • Ryan, John F.;
    • Groot, Vincent P.;
    • Rosati, Lauren M.;
    • Hacker-Prietz, Amy;
    • Narang, Amol K.;
    • McNutt, Todd R.;
    • Jackson, Juan F.;
    • Le, Dung T.;
    • Jaffee, Elizabeth M.;
    • Zheng, Lei;
    • Laheru, Daniel A.;
    • He, Jin;
    • Pawlik, Timothy M.;
    • Weiss, Matthew J.;
    • Wolfgang, Christopher L.;
    • Herman, Joseph M.
    Publication type:
    Article
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    The Role of Stereotactic Body Radiation Therapy for Pancreatic Cancer: A Single-Institution Experience.

    Published in:
    Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2015, v. 22, n. 7, p. 2352, doi. 10.1245/s10434-014-4274-5
    By:
    • Moningi, Shalini;
    • Dholakia, Avani;
    • Raman, Siva;
    • Blackford, Amanda;
    • Cameron, John;
    • Le, Dung;
    • Jesus-Acosta, Ana;
    • Hacker-Prietz, Amy;
    • Rosati, Lauren;
    • Assadi, Ryan;
    • Dipasquale, Shirl;
    • Pawlik, Timothy;
    • Zheng, Lei;
    • Weiss, Matthew;
    • Laheru, Daniel;
    • Wolfgang, Christopher;
    • Herman, Joseph
    Publication type:
    Article
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    A Safety and Feasibility Study of an Allogeneic Colon Cancer Cell Vaccine Administered with a Granulocyte-Macrophage Colony Stimulating Factor-Producing Bystander Cell Line in Patients with Metastatic Colorectal Cancer.

    Published in:
    Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2014, v. 21, n. 12, p. 3931, doi. 10.1245/s10434-014-3844-x
    By:
    • Zheng, Lei;
    • Edil, Barish;
    • Soares, Kevin;
    • El-Shami, Khaled;
    • Uram, Jennifer;
    • Judkins, Carol;
    • Zhang, Zhe;
    • Onners, Beth;
    • Laheru, Daniel;
    • Pardoll, Drew;
    • Jaffee, Elizabeth;
    • Schulick, Richard
    Publication type:
    Article
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    The Impact of Postoperative Complications on the Administration of Adjuvant Therapy Following Pancreaticoduodenectomy for Adenocarcinoma.

    Published in:
    Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2014, v. 21, n. 9, p. 2873, doi. 10.1245/s10434-014-3722-6
    By:
    • Wu, Wenchuan;
    • He, Jin;
    • Cameron, John;
    • Makary, Martin;
    • Soares, Kevin;
    • Ahuja, Nita;
    • Rezaee, Neda;
    • Herman, Joseph;
    • Zheng, Lei;
    • Laheru, Daniel;
    • Choti, Michael;
    • Hruban, Ralph;
    • Pawlik, Timothy;
    • Wolfgang, Christopher;
    • Weiss, Matthew
    Publication type:
    Article
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    Adjuvant Chemoradiation Therapy for Adenocarcinoma of the Distal Pancreas.

    Published in:
    Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2010, v. 17, n. 12, p. 3112, doi. 10.1245/s10434-010-1200-3
    By:
    • Redmond, Kristin;
    • Wolfgang, Christopher;
    • Sugar, Elizabeth;
    • Ahn, Julia;
    • Nathan, Hari;
    • Laheru, Daniel;
    • Edil, Barish;
    • Choti, Michael;
    • Pawlik, Timothy;
    • Hruban, Ralph;
    • Cameron, John;
    • Herman, Joseph
    Publication type:
    Article
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    Adjuvant Chemoradiation for Pancreatic Adenocarcinoma: The Johns Hopkins Hospital—Mayo Clinic Collaborative Study.

    Published in:
    Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2010, v. 17, n. 4, p. 981, doi. 10.1245/s10434-009-0743-7
    By:
    • Hsu, Charles;
    • Herman, Joseph;
    • Corsini, Michele;
    • Winter, Jordan;
    • Callister, Matthew;
    • Haddock, Michael;
    • Cameron, John;
    • Pawlik, Timothy;
    • Schulick, Richard;
    • Wolfgang, Christopher;
    • Laheru, Daniel;
    • Farnell, Michael;
    • Swartz, Michael;
    • Gunderson, Leonard;
    • Miller, Robert
    Publication type:
    Article
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    Postoperative surveillance of pancreatic ductal adenocarcinoma (PDAC) recurrence: practice pattern on standardized imaging and reporting from the society of abdominal radiology disease focus panel on PDAC.

    Published in:
    Abdominal Radiology, 2023, v. 48, n. 1, p. 318, doi. 10.1007/s00261-022-03693-0
    By:
    • Chu, Linda C.;
    • Wang, Zhen J.;
    • Kambadakone, Avinash;
    • Hecht, Elizabeth M.;
    • He, Jin;
    • Narang, Amol K.;
    • Laheru, Daniel A.;
    • Arif-Tiwari, Hina;
    • Bhosale, Priya;
    • Bolan, Candice W.;
    • Brook, Olga R.;
    • Bezuidenhout, Abraham F.;
    • Do, Richard K. G.;
    • Galgano, Samuel J.;
    • Goenka, Ajit H.;
    • Guimaraes, Alexander R.;
    • Hough, David M.;
    • Kulkarni, Naveen;
    • Le, Ott;
    • Luk, Lyndon
    Publication type:
    Article
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    High local failure rates despite high margin‐negative resection rates in a cohort of borderline resectable and locally advanced pancreatic cancer patients treated with stereotactic body radiation therapy following multi‐agent chemotherapy.

    Published in:
    Cancer Medicine, 2022, v. 11, n. 7, p. 1659, doi. 10.1002/cam4.4527
    By:
    • Hill, Colin;
    • Sehgal, Shuchi;
    • Fu, Wei;
    • Hu, Chen;
    • Reddy, Abhinav;
    • Thompson, Elizabeth;
    • Hacker‐Prietz, Amy;
    • Le, Dung;
    • De Jesus‐Acosta, Ana;
    • Lee, Valerie;
    • Zheng, Lei;
    • Laheru, Daniel A.;
    • Burns, William;
    • Weiss, Matthew;
    • Wolfgang, Christopher;
    • He, Jin;
    • Herman, Joseph M.;
    • Meyer, Jeffrey;
    • Narang, Amol
    Publication type:
    Article
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    Recent progress in pancreatic cancer.

    Published in:
    CA: A Cancer Journal for Clinicians, 2013, v. 63, n. 5, p. 318, doi. 10.3322/caac.21190
    By:
    • Wolfgang, Christopher L.;
    • Herman, Joseph M.;
    • Laheru, Daniel A.;
    • Klein, Alison P.;
    • Erdek, Michael A.;
    • Fishman, Elliot K.;
    • Hruban, Ralph H.
    Publication type:
    Article
    45

    Development of thyroglobulin antibodies after GVAX immunotherapy is associated with prolonged survival.

    Published in:
    International Journal of Cancer, 2015, v. 136, n. 1, p. 127, doi. 10.1002/ijc.28973
    By:
    • De Remigis, Alessandra;
    • de Gruijl, Tanja D.;
    • Uram, Jennifer N.;
    • Tzou, Schey‐Cherng;
    • Iwama, Shintaro;
    • Talor, Monica V.;
    • Armstrong, Todd D.;
    • Santegoets, Saskia J.A.M.;
    • Slovin, Susan F.;
    • Zheng, Lei;
    • Laheru, Daniel A.;
    • Jaffee, Elizabeth M.;
    • Gerritsen, Winald R.;
    • van den Eertwegh, Alfons J.M.;
    • Le, Dung T.;
    • Caturegli, Patrizio
    Publication type:
    Article
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