Works by Ladant, Daniel

Results: 41

CyaA translocation across eukaryotic cell membranes.

Published in:

Frontiers in Molecular Biosciences, 2024, p. 1, doi. 10.3389/fmolb.2024.1359408

By:

Abettan, Amiel;
Nguyen, Minh-Ha;
Ladant, Daniel;
Monticelli, Luca;
Chenal, Alexandre

Publication type:

Article

Characterization of interactions between inclusion membrane proteins from Chlamydia trachomatis.

Published in:

Frontiers in Cellular & Infection Microbiology, 2015, p. 1, doi. 10.3389/fcimb.2015.00013

By:

Gauliard, Emilie;
Ouellette, Scot P.;
Rueden, Kelsey J.;
Ladant, Daniel

Publication type:

Article

Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin.

Published in:

PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0228606

By:

Angely, Christelle;
Ladant, Daniel;
Planus, Emmanuelle;
Louis, Bruno;
Filoche, Marcel;
Chenal, Alexandre;
Isabey, Daniel

Publication type:

Article

Efficient display of two enzymes on filamentous phage using an improved signal sequence.

Published in:

Molecular Biotechnology, 2003, v. 24, n. 1, p. 1, doi. 10.1385/MB:24:1:1

By:

Strobel, Heike;
Ladant, Daniel;
Jestin, Jean-Luc

Publication type:

Article

Prevalence of ExoY Activity in Pseudomonas aeruginosa Reference Panel Strains and Impact on Cytotoxicity in Epithelial Cells.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.666097

By:

Silistre, Hazel;
Raoux-Barbot, Dorothée;
Mancinelli, Federica;
Sangouard, Flora;
Dupin, Alice;
Belyy, Alexander;
Deruelle, Vincent;
Renault, Louis;
Ladant, Daniel;
Touqui, Lhousseine;
Mechold, Undine

Publication type:

Article

Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00919

By:

Arumugham, Vijay B.;
Ulivieri, Cristina;
Onnis, Anna;
Finetti, Francesca;
Tonello, Fiorella;
Ladant, Daniel;
Baldari, Cosima T.

Publication type:

Article

SEC‐SAXS and HDX‐MS: A powerful combination. The case of the calcium‐binding domain of a bacterial toxin.

Published in:

Biotechnology & Applied Biochemistry, 2018, v. 65, n. 1, p. 62, doi. 10.1002/bab.1577

By:

O'Brien, Darragh P.;
Brier, Sébastien;
Ladant, Daniel;
Durand, Dominique;
Chenal, Alexandre;
Vachette, Patrice

Publication type:

Article

Lack of MHC class II molecules favors CD8<sup>+</sup> T-cell infiltration into tumors associated with an increased control of tumor growth.

Published in:

OncoImmunology, 2018, v. 7, n. 3, p. 1, doi. 10.1080/2162402X.2017.1404213

By:

Chaoul, Nada;
Tang, Alexandre;
Desrues, Belinda;
Oberkampf, Marine;
Fayolle, Catherine;
Ladant, Daniel;
Sainz-Perez, Alexander;
Leclerc, Claude

Publication type:

Article

The effector protein ExoY secreted by Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for GTP.

Published in:

2011

By:

Voigt, Ulrike;
Burhenne, Heike;
Sonnow, Lena;
Wölfel, Christine;
Spangler, Corinna;
Ladant, Daniel;
Frank, Dara W;
Kaever, Volkhard;
Seifert, Roland

Publication type:

Abstract

Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium.

Published in:

BMC Biology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12915-022-01381-5

By:

Léger, Corentin;
Pitard, Irène;
Sadi, Mirko;
Carvalho, Nicolas;
Brier, Sébastien;
Mechaly, Ariel;
Raoux-Barbot, Dorothée;
Davi, Maryline;
Hoos, Sylviane;
Weber, Patrick;
Vachette, Patrice;
Durand, Dominique;
Haouz, Ahmed;
Guijarro, J. Iñaki;
Ladant, Daniel;
Chenal, Alexandre

Publication type:

Article

Analysis of MreB interactors in Chlamydia reveals a RodZ homolog but fails to detect an interaction with MraY.

Published in:

Frontiers in Microbiology, 2014, v. 5, p. 1, doi. 10.3389/fmicb.2014.00279

By:

Ouellette, Scot P.;
Rueden, Kelsey J.;
Gauliard, Emilie;
Persons, Logan;
de Boer, Piet A.;
Ladant, Daniel

Publication type:

Article

Analysis of MreB interactors in Chlamydia reveals a RodZ homolog but fails to detect an interaction with MraY.

Published in:

Frontiers in Microbiology, 2014, v. 5, p. 1, doi. 10.3389/fmicb.2014.00279

By:

Ouellette, Scot P.;
Rueden, Kelsey J.;
Gauliard, Emilie;
Persons, Logan;
de Boer, Piet A.;
Ladant, Daniel

Publication type:

Article

The Adenylate Cyclase Toxins of Bacillus anthracis and Bordetella pertussis Promote Th2 Cell Development by Shaping T Cell Antigen Receptor Signaling.

Published in:

PLoS Pathogens, 2009, v. 5, n. 3, p. 1, doi. 10.1371/journal.ppat.1000325

By:

Paccani, Silvia Rossi;
Benagiano, Marisa;
Capitani, Nagaja;
Zornetta, Irene;
Ladant, Daniel;
Montecucco, Cesare;
D'Elios, Mario M.;
Baldari, Cosima T.

Publication type:

Article

Large-scale study of the interactions between proteins involved in type IV pilus biology in Neisseria meningitidis: characterization of a subcomplex involved in pilus assembly.

Published in:

Molecular Microbiology, 2012, v. 84, n. 5, p. 857, doi. 10.1111/j.1365-2958.2012.08062.x

By:

Georgiadou, Michaella;
Castagnini, Marta;
Karimova, Gouzel;
Ladant, Daniel;
Pelicic, Vladimir

Publication type:

Article

Recombinant adenylate cyclase toxin of Bordetella pertussis induces cytotoxic T lymphocyte responses against HLA*0201-restricted melanoma epitopes.

Published in:

International Immunology, 2003, v. 15, n. 12, p. 1423, doi. 10.1093/intimm/dxg144

By:

Gilles Dadaglio;
Sandra Morel;
Cécile Bauche;
Zhora Moukrim;
François A. Lemonnier;
Benoît J. Van den Eynde;
Daniel Ladant;
Claude Leclerc

Publication type:

Article

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins.

Published in:

Nature Communications, 2016, v. 7, n. 12, p. 13582, doi. 10.1038/ncomms13582

By:

Belyy, Alexander;
Raoux-Barbot, Dorothée;
Saveanu, Cosmin;
Namane, Abdelkader;
Ogryzko, Vasily;
Worpenberg, Lina;
David, Violaine;
Henriot, Veronique;
Fellous, Souad;
Merrifield, Christien;
Assayag, Elodie;
Ladant, Daniel;
Renault, Louis;
Mechold, Undine

Publication type:

Article

Toxins, Pathogenicity, Anti-Toxins, a Bicentennial Contribution.

Published in:

Toxins, 2024, v. 16, n. 2, p. 97, doi. 10.3390/toxins16020097

By:

Popoff, Michel R.;
Ladant, Daniel

Publication type:

Article

Animal Toxins: A Historical Outlook at the Institut Pasteur of Paris.

Published in:

Toxins, 2023, v. 15, n. 7, p. 462, doi. 10.3390/toxins15070462

By:

Popoff, Michel R.;
Faure, Grazyna;
Legout, Sandra;
Ladant, Daniel

Publication type:

Article

Editorial of the Special Issue "Toxins: Mr Hyde or Dr Jekyll?".

Published in:

2023

By:

Ladant, Daniel;
Prévost, Gilles;
Popoff, Michel R.;
Benoit, Evelyne

Publication type:

Editorial

A Robust and Sensitive Spectrophotometric Assay for the Enzymatic Activity of Bacterial Adenylate Cyclase Toxins.

Published in:

Toxins, 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/toxins14100691

By:

Davi, Marilyne;
Sadi, Mirko;
Pitard, Irene;
Chenal, Alexandre;
Ladant, Daniel

Publication type:

Article

Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0206133

By:

Raoux-Barbot, Dorothée;
Belyy, Alexander;
Worpenberg, Lina;
Montluc, Sabrina;
Deville, Celia;
Henriot, Véronique;
Velours, Christophe;
Ladant, Daniel;
Renault, Louis;
Mechold, Undine

Publication type:

Article

Exposure to Bordetella pertussis adenylate cyclase toxin affects integrin-mediated adhesion and mechanics in alveolar epithelial cells.

Published in:

Biology of the Cell (Wiley-Blackwell), 2017, v. 109, n. 8, p. 293, doi. 10.1111/boc.201600082

By:

Angely, Christelle;
Nguyen, Ngoc‐Minh;
Andre Dias, Sofia;
Planus, Emmanuelle;
Pelle, Gabriel;
Louis, Bruno;
Filoche, Marcel;
Chenal, Alexandre;
Ladant, Daniel;
Isabey, Daniel

Publication type:

Article

Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.

Published in:

PLoS Biology, 2017, v. 15, n. 12, p. 1, doi. 10.1371/journal.pbio.2004486

By:

O’Brien, Darragh P.;
Durand, Dominique;
Voegele, Alexis;
Hourdel, Véronique;
Davi, Marilyne;
Chamot-Rooke, Julia;
Vachette, Patrice;
Brier, Sébastien;
Ladant, Daniel;
Chenal, Alexandre

Publication type:

Article

Cell entry and cAMP imaging of anthrax edema toxin.

Published in:

EMBO Journal, 2006, v. 25, n. 22, p. 5405, doi. 10.1038/sj.emboj.7601408

By:

Dal Molin, Federica;
Tonello, Fiorella;
Ladant, Daniel;
Zornetta, Irene;
Zamparo, Ilaria;
Di Benedetto, Giulietta;
Zaccolo, Manuela;
Montecucco, Cesare

Publication type:

Article

Post-translational acylation controls the folding and functions of the CyaA RTX toxin.

Published in:

FASEB Journal, 2019, v. 33, n. 9, p. 10065, doi. 10.1096/fj.201802442RR

By:

O'Brien, Darragh P.;
Cannella, Sara E.;
Voegele, Alexis;
Raoux-Barbot, Dorothée;
Davi, Marilyne;
Douché, Thibaut;
Matondo, Mariette;
Brier, Sébastien;
Ladant, Daniel;
Chenal, Alexandre

Publication type:

Article

Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.

Published in:

PLoS Pathogens, 2023, v. 19, n. 9, p. 1, doi. 10.1371/journal.ppat.1011654

By:

Teixeira-Nunes, Magda;
Retailleau, Pascal;
Raoux-Barbot, Dorothée;
Comisso, Martine;
Missinou, Anani Amegan;
Velours, Christophe;
Plancqueel, Stéphane;
Ladant, Daniel;
Mechold, Undine;
Renault, Louis

Publication type:

Article

A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells.

Published in:

Advanced Science, 2021, v. 8, n. 9, p. 1, doi. 10.1002/advs.202003630

By:

Voegele, Alexis;
Sadi, Mirko;
O'Brien, Darragh Patrick;
Gehan, Pauline;
Raoux‐Barbot, Dorothée;
Davi, Maryline;
Hoos, Sylviane;
Brûlé, Sébastien;
Raynal, Bertrand;
Weber, Patrick;
Mechaly, Ariel;
Haouz, Ahmed;
Rodriguez, Nicolas;
Vachette, Patrice;
Durand, Dominique;
Brier, Sébastien;
Ladant, Daniel;
Chenal, Alexandre

Publication type:

Article

Repeat sequences in the Bordetella pertussis adenylate cyclase toxin can be recognized as alternative carboxy- proximal secretion signals by the Escherichia coli α-haemolysin translocator.

Published in:

Molecular Microbiology, 1993, v. 9, n. 5, p. 999, doi. 10.1111/j.1365-2958.1993.tb01229.x

By:

Šebo, Peter;
Ladant, Daniel

Publication type:

Article

Report from the 27th (Virtual) Meeting on Toxinology, "Toxins: Mr Hyde or Dr Jekyll?", Organized by the French Society of Toxinology, 9–10 December 2021.

Published in:

Toxins, 2022, v. 14, n. 2, p. N.PAG, doi. 10.3390/toxins14020110

By:

Ladant, Daniel;
Marchot, Pascale;
Diochot, Sylvie;
Prévost, Gilles;
Popoff, Michel R.;
Benoit, Evelyne

Publication type:

Article

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Vaccine Development and Other Biotechnological Purposes.

Published in:

Toxins, 2021, v. 13, n. 2, p. 83, doi. 10.3390/toxins13020083

By:

Ladant, Daniel

Publication type:

Article

The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro.

Published in:

Toxins, 2019, v. 11, n. 2, p. 111, doi. 10.3390/toxins11020111

By:

Voegele, Alexis;
Sadi, Mirko;
Raoux-Barbot, Dorothée;
Douché, Thibaut;
Matondo, Mariette;
Ladant, Daniel;
Chenal, Alexandre

Publication type:

Article

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy.

Published in:

Toxins, 2018, v. 10, n. 7, p. 302, doi. 10.3390/toxins10070302

By:

Chenal, Alexandre;
Ladant, Daniel

Publication type:

Article

Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region.

Published in:

Toxins, 2017, v. 9, n. 11, p. 369, doi. 10.3390/toxins9110369

By:

Voegele, Alexis;
Subrini, Orso;
Sapay, Nicolas;
Ladant, Daniel;
Chenal, Alexandre

Publication type:

Article

Disorder-to-Order Transition in the CyaA Toxin RTX Domain: Implications for Toxin Secretion.

Published in:

Toxins, 2015, v. 7, n. 1, p. 1, doi. 10.3390/toxins7010001

By:

Sotomayor-Pérez, Ana-Cristina;
Ladant, Daniel;
Chenal, Alexandre

Publication type:

Article

Molecular Motions as a Drug Target: Mechanistic Simulations of Anthrax Toxin Edema Factor Function Led to the Discovery of Novel Allosteric Inhibitors.

Published in:

Toxins, 2012, v. 4, n. 8, p. 580, doi. 10.3390/toxins4080580

By:

Laine, Élodie;
Martínez, Leandro;
Ladant, Daniel;
Malliavin, Thérèse;
Blondel, Arnaud

Publication type:

Article

A Tethered Bilayer Assembled on Top of Immobilized Calmodulin to Mimic Cellular Compartmentalization.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0019101

By:

Rossi, Claire;
Doumiati, Samah;
Lazzarelli, Clarine;
Davi, Marilyne;
Meddar, Fetta;
Ladant, Daniel;
Chopineau, Joël

Publication type:

Article

Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.

Published in:

Scientific Reports, 2017, p. 42065, doi. 10.1038/srep42065

By:

Cannella, Sara E.;
Ntsogo Enguéné, Véronique Yvette;
Davi, Marilyne;
Malosse, Christian;
Sotomayor Pérez, Ana Cristina;
Chamot-Rooke, Julia;
Vachette, Patrice;
Durand, Dominique;
Ladant, Daniel;
Chenal, Alexandre

Publication type:

Article

Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion.

Published in:

Scientific Reports, 2015, p. 14223, doi. 10.1038/srep14223

By:

O'Brien, Darragh P.;
Hernandez, Belen;
Durand, Dominique;
Hourdel, Véronique;
Sotomayor-Pérez, Ana-Cristina;
Vachette, Patrice;
Ghomi, Mahmoud;
Chamot-Rooke, Julia;
Ladant, Daniel;
Brier, Sébastien;
Chenal, Alexandre

Publication type:

Article

In vivo receptor-mediated delivery of a recombinant invasive bacterial toxoid to CD11c.

Published in:

European Journal of Immunology, 2002, v. 32, n. 11, p. 3071, doi. 10.1002/1521-4141(200211)32:11<3071::AID-IMMU3071>3.0.CO;2-A

By:

Guermonprez, Pierre;
Fayolle, Catherine;
Rojas, Marie-Jésus;
Rescigno, Maria;
Ladant, Daniel;
Leclerc, Claude

Publication type:

Article

A Gateway<sup>®</sup>-compatible bacterial adenylate cyclase-based two-hybrid system.

Published in:

Environmental Microbiology Reports, 2014, v. 6, n. 3, p. 259, doi. 10.1111/1758-2229.12123

By:

Ouellette, Scot P.;
Gauliard, Emilie;
Antosová, Zuzana;
Ladant, Daniel

Publication type:

Article

Interaction network among de novo purine nucleotide biosynthesis enzymes in Escherichia coli.

Published in:

FEBS Journal, 2023, v. 290, n. 12, p. 3165, doi. 10.1111/febs.16746

By:

Gedeon, Antoine;
Karimova, Gouzel;
Ayoub, Nour;
Dairou, Julien;
Giai Gianetto, Quentin;
Vichier‐Guerre, Sophie;
Vidalain, Pierre‐Olivier;
Ladant, Daniel;
Munier‐Lehmann, Hélène

Publication type:

Article