Works by Laakso M

Results: 196

Insulin action and age. European Group for the Study of Insulin Resistance (EGIR).

Published in:

1996

By:

Ferrannini E;
Vichi S;
Beck-Nielsen H;
Laakso M;
Paolisso G;
Smith U;
European Group for the Study of Insulin Resistance;
Ferrannini, E;
Vichi, S;
Beck-Nielsen, H;
Laakso, M;
Paolisso, G;
Smith, U

Publication type:

journal article

Treatment of hypercholesterolemia and combined hyperlipidemia with simvastatin and gemfibrozil in patients with NIDDM. A multicenter comparison study.

Published in:

1998

By:

Tikkanen MJ;
Laakso M;
Ilmonen M;
Helve E;
Kaarsalo E;
Kilkki E;
Saltevo J;
Scandinavian Simvastation Survival Study Group;
Tikkanen, M J;
Laakso, M;
Ilmonen, M;
Helve, E;
Kaarsalo, E;
Kilkki, E;
Saltevo, J

Publication type:

journal article

High circulating levels of RBP4 and mRNA levels of aP2, PGC-1alpha and UCP-2 predict improvement in insulin sensitivity following pioglitazone treatment of drug-naïve type 2 diabetic subjects.

Published in:

2008

By:

Hammarstedt A;
Pihlajamäki J;
Graham TE;
Kainulainen S;
Kahn BB;
Laakso M;
Smith U;
Hammarstedt, A;
Pihlajamäki, J;
Graham, T E;
Kainulainen, S;
Kahn, B B;
Laakso, M;
Smith, U

Publication type:

journal article

Mortality and causes of death for people with multiple sclerosis: a Finnish nationwide register study.

Published in:

Journal of Neurology, 2025, v. 272, n. 5, p. 1, doi. 10.1007/s00415-025-13112-1

By:

Kuutti, Katariina;
Laakso, Sini M.;
Viitala, Matias;
Atula, Sari;
Soilu-Hänninen, Merja

Publication type:

Article

Effects of a Digital Care Pathway for Multiple Sclerosis: Observational Study.

Published in:

JMIR Human Factors, 2024, v. 11, p. 1, doi. 10.2196/51872

By:

Vesinurm, Märt;
Maunula, Anna;
Olli, Päivi;
Lillrank, Paul;
Ijäs, Petra;
Torkki, Paulus;
Mäkitie, Laura;
Laakso, Sini M

Publication type:

Article

Categorization of voice disorders with six perceptual dimensions.

Published in:

1997

By:

Leinonen L;
Hiltunen T;
Laakso M;
Rihkanen H;
Poppius H

Publication type:

Journal Article

Clinical profiles of post‐load glucose subgroups and their association with glycaemic traits over time: An IMI‐DIRECT study.

Published in:

Diabetic Medicine, 2021, v. 38, n. 2, p. 1, doi. 10.1111/dme.14428

By:

Obura, M.;
Beulens, J. W. J.;
Slieker, R.;
Koopman, A. D. M.;
Hoekstra, T.;
Nijpels, G.;
Elders, P.;
Dekker, J. M.;
Koivula, R. W.;
Kurbasic, A.;
Laakso, M.;
Hansen, T. H.;
Ridderstråle, M.;
Hansen, T.;
Pavo, I.;
Forgie, I.;
Jablonka, B.;
Ruetten, H.;
Mari, A.;
McCarthy, M. I.

Publication type:

Article

α-Synuclein pathology is highly dependent on the case selection.

Published in:

Neuropathology & Applied Neurobiology, 2001, v. 27, n. 4, p. 314, doi. 10.1046/j.0305-1846.2001.00342.x

By:

Parkkinen, L.;
Soininen, H.;
Laakso, M.;
Alafuzoff, I.

Publication type:

Article

Epidemiology and prevention.

Published in:

European Heart Journal, 1996, v. 17, n. 5, p. 682, doi. 10.1093/oxfordjournals.eurheartj.a014934

By:

Miettinen, H.;
Lehto, S.;
Saikku, P.;
Haffner, S. M.;
Rönnemaa, T.;
Pyörälä, K.;
Laakso, M.

Publication type:

Article

Infertility as a lonely struggle? Coping stories of previously infertile women.

Published in:

Health Care for Women International, 2023, v. 44, n. 4, p. 397, doi. 10.1080/07399332.2021.2007246

By:

Lehto, Siru;
Sevón, E.;
Laakso, M.-L.;
Rönkä, A.

Publication type:

Article

Effect of the Pro12Ala Polymorphism in the Peroxisome Proliferator-Activated Receptor (PPAR) γ2 Gene on the Expression of PPARγ Target Genes in Adipose Tissue of Massively Obese Subjects

Published in:

Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 4, p. 1717, doi. 10.1210/jc.2002-020603

By:

KOLEHMAINEN, M.;
UUSITUPA, M. I. J.;
ALHAVA, E.;
LAAKSO, M.;
VIDAL, H.

Publication type:

Article

Acute Insulin Response Tests for the Differential Diagnosis of Congenital Hyperinsulinism.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 10, p. 4502, doi. 10.1210/jc.2002-020378

By:

HUOPIO, H.;
JÄÄSKELÄINEN, J.;
KOMULAINEN, J.;
MIETTINEN, R.;
KÄRKKÄINEN, P.;
LAAKSO, M.;
TAPANAINEN, P.;
VOUTILAINEN, R.;
OTONKOSKI, T.

Publication type:

Article

Two Polymorphisms in the Peroxisome Proliferator-Activated Receptor-γ Gene Are Associated with Severe Overweight among Obese Women.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 10, p. 3708, doi. 10.1210/jcem.84.10.6061

By:

VALVE, R.;
SIVENIUS, K.;
MIETTINEN, R.;
PIHLAJAMÄKI, J.;
RISSANEN, A.;
DEEB, S. S.;
AUWERX, J.;
UUSITUPA, M.;
LAAKSO, M.

Publication type:

Article

V3 Loop Truncations in HIV-1 Envelope Impart Resistance to Coreceptor Inhibitors and Enhanced Sensitivity to Neutralizing Antibodies.

Published in:

PLoS Pathogens, 2007, v. 3, n. 8, p. 1118, doi. 10.1371/journal.ppat.0030117

By:

Laakso, Meg M.;
Fang-Hua Lee;
Haggarty, Beth;
Agrawal, Caroline;
Nolan, Katrina M.;
Biscone, Mark;
Romano, Josephine;
Jordan, Andrea P. O.;
Leslie, George J.;
Meissner, Eric G.;
Su, Lishan;
Hoxie, James A.;
Doms, Robert W.

Publication type:

Article

Pathogenesis and treatment of diabetic vascular disease - illustrated by two cases.

Published in:

2006

By:

Smith U;
Laakso M;
Eliasson B;
Wesslau C;
Borén J;
Wiklund O;
Attvall S

Publication type:

Journal Article

Pathogenesis and treatment of diabetic vascular disease – illustrated by two cases.

Published in:

Journal of Internal Medicine, 2006, v. 260, n. 5, p. 409, doi. 10.1111/j.1365-2796.2006.01712.x

By:

Smith, U.;
Laakso, M.;
Eliasson, B.;
Wesslau, C.;
Borén, J.;
Wiklund, O.;
Attvall, S.

Publication type:

Article

The G-250A substitution in the promoter region of the hepatic lipase gene is associated with the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

Published in:

Journal of Internal Medicine, 2005, v. 257, n. 2, p. 185, doi. 10.1111/j.1365-2796.2004.01435.x

By:

Zacharova, J.;
Todorova, B. R.;
Chiasson, J.-L.;
Laakso, M.

Publication type:

Article

Cardiovascular disease in type 2 diabetes: challenge for treatment and prevention.

Published in:

2001

By:

Laakso, M.

Publication type:

journal article

Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle.

Published in:

Diabetologia, 2012, v. 55, n. 6, p. 1797, doi. 10.1007/s00125-012-2511-7

By:

Nerstedt, A.;
Cansby, E.;
Andersson, C.;
Laakso, M.;
Stančáková, A.;
Blüher, M.;
Smith, U.;
Mahlapuu, M.

Publication type:

Article

Natural history and physiological determinants of changes in glucose tolerance in a non-diabetic population: the RISC Study.

Published in:

Diabetologia, 2011, v. 54, n. 6, p. 1507, doi. 10.1007/s00125-011-2112-x

By:

Ferrannini, E.;
Natali, A.;
Muscelli, E.;
Nilsson, P.;
Golay, A.;
Laakso, M.;
Beck-Nielsen, H.;
Mari, A.

Publication type:

Article

Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B.

Published in:

Diabetologia, 2011, v. 54, n. 4, p. 795, doi. 10.1007/s00125-010-2038-8

By:

Hribal, M.;
Presta, I.;
Procopio, T.;
Marini, M.;
Stančáková, A.;
Kuusisto, J.;
Andreozzi, F.;
Hammarstedt, A.;
Jansson, P.-A.;
Grarup, N.;
Hansen, T.;
Walker, M.;
Stefan, N.;
Fritsche, A.;
Häring, H.;
Pedersen, O.;
Smith, U.;
Laakso, M.;
Sesti, G.

Publication type:

Article

A novel surrogate index for hepatic insulin resistance.

Published in:

Diabetologia, 2011, v. 54, n. 3, p. 540, doi. 10.1007/s00125-010-1966-7

By:

Vangipurapu, J.;
Stančáková, A.;
Kuulasmaa, T.;
Paananen, J.;
Kuusisto, J.;
Ferrannini, E.;
Laakso, M.

Publication type:

Article

Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men.

Published in:

Diabetologia, 2011, v. 54, n. 3, p. 563, doi. 10.1007/s00125-010-1977-4

By:

Vangipurapu, J.;
Stančáková, A.;
Pihlajamäki, J.;
Kuulasmaa, T.;
Paananen, J.;
Kuusisto, J.;
Ferrannini, E.;
Laakso, M.

Publication type:

Article

A role for coding functional variants in HNF4A in type 2 diabetes susceptibility.

Published in:

Diabetologia, 2011, v. 54, n. 1, p. 111, doi. 10.1007/s00125-010-1916-4

By:

Jafar-Mohammadi, B.;
Groves, C.;
Gjesing, A.;
Herrera, B.;
Winckler, W.;
Stringham, H.;
Morris, A.;
Lauritzen, T.;
Doney, A.;
Weedon, M.;
Swift, A.;
Kuusisto, J.;
Laakso, M.;
Altshuler, D.;
Hattersley, A.;
Collins, F.;
Boehnke, M.;
Hansen, T.;
Pedersen, O.;
Palmer, C.

Publication type:

Article

Proteinuria modifies the effects of physical activity on total and cardiovascular disease mortality rates in patients with type 2 diabetes.

Published in:

Diabetologia, 2010, v. 53, n. 9, p. 1886, doi. 10.1007/s00125-010-1812-y

By:

Vepsäläinen, T.;
Soinio, M.;
Lehto, S.;
Juutilainen, A.;
Laakso, M.;
Rönnemaa, T.

Publication type:

Article

Impaired beta cell glucose sensitivity rather than inadequate compensation for insulin resistance is the dominant defect in glucose intolerance.

Published in:

Diabetologia, 2010, v. 53, n. 4, p. 749, doi. 10.1007/s00125-009-1647-6

By:

Mari, A.;
Tura, A.;
Natali, A.;
Laville, M.;
Laakso, M.;
Gabriel, R.;
Beck-Nielsen, H.;
Ferrannini, E.

Publication type:

Article

Erratum to: Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes.

Published in:

2009

By:

Pulizzi, N.;
Lyssenko, V.;
Jonsson, A.;
Osmond, C.;
Laakso, M.;
Kajantie, E.;
Barker, D.;
Groop, L.;
Eriksson, J.

Publication type:

Correction Notice

Common genetic variation in the melatonin receptor 1B gene ( MTNR1B) is associated with decreased early-phase insulin response.

Published in:

Diabetologia, 2009, v. 52, n. 8, p. 1537, doi. 10.1007/s00125-009-1392-x

By:

Langenberg, C.;
Pascoe, L.;
Mari, A.;
Tura, A.;
Laakso, M.;
Frayling, T.;
Barroso, I.;
Loos, R.;
Wareham, N.;
Walker, M.

Publication type:

Article

Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes.

Published in:

Diabetologia, 2009, v. 52, n. 5, p. 825, doi. 10.1007/s00125-009-1291-1

By:

Pulizzi, N.;
Lyssenko, V.;
Jonsson, A.;
Osmond, C.;
Laakso, M.;
Kajantie, E.;
Barker, D.;
Groop, L.;
Eriksson, J.

Publication type:

Article

Not for the eyes only: PAX6 and glucose metabolism.

Published in:

Diabetologia, 2009, v. 52, n. 3, p. 381, doi. 10.1007/s00125-008-1251-1

By:

Laakso, M.

Publication type:

Article

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients—the EUGENE2 study.

Published in:

Diabetologia, 2008, v. 51, n. 5, p. 816, doi. 10.1007/s00125-008-0955-6

By:

Boesgaard, T.;
Žilinskaitė, J.;
Vänttinen, M.;
Laakso, M.;
Jansson, P.-A.;
Hammarstedt, A.;
Smith, U.;
Stefan, N.;
Fritsche, A.;
Häring, H.;
Hribal, M.;
Sesti, G.;
Zobel, D.;
Pedersen, O.;
Hansen, T.

Publication type:

Article

Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study.

Published in:

Diabetologia, 2008, v. 51, n. 3, p. 502, doi. 10.1007/s00125-007-0899-2

By:

Laakso, M.;
Zilinskaite, J.;
Hansen, T.;
Boesgaard, T.;
Vänttinen, M.;
Stančáková, A.;
Jansson, P.-A.;
Pellmé, F.;
Holst, J.;
Kuulasmaa, T.;
Hribal, M.;
Sesti, G.;
Stefan, N.;
Fritsche, A.;
Häring, H.;
Pedersen, O.;
Smith, U.

Publication type:

Article

Increased serum levels of advanced glycation endproducts predict total, cardiovascular and coronary mortality in women with type 2 diabetes: a population-based 18 year follow-up study.

Published in:

Diabetologia, 2007, v. 50, n. 7, p. 1409, doi. 10.1007/s00125-007-0687-z

By:

Kilhovd, B.;
Juutilainen, A.;
Lehto, S.;
Rönnemaa, T.;
Torjesen, P.;
Hanssen, K.;
Laakso, M.

Publication type:

Article

Association of sequence variations in the gene encoding adiponectin receptor 1 ( ADIPOR1) with body size and insulin levels. The Finnish Diabetes Prevention Study.

Published in:

Diabetologia, 2006, v. 49, n. 8, p. 1795, doi. 10.1007/s00125-006-0291-7

By:

Siitonen, N.;
Pulkkinen, L.;
Mager, U.;
Lindström, J.;
Eriksson, J.;
Valle, T. T.;
Hämäläinen, H.;
Ilanne-Parikka, P.;
Keinänen-Kiukaanniemi, S.;
Tuomilehto, J.;
Laakso, M.;
Uusitupa, M.

Publication type:

Article

Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes.

Published in:

Diabetologia, 2006, v. 49, n. 7, p. 1560, doi. 10.1007/s00125-006-0270-z

By:

Pihlajamäki, J.;
Salmenniemi, U.;
Vänttinen, M.;
Ruotsalainen, E.;
Kuusisto, J.;
Vauhkonen, I.;
Kainulainen, S.;
Ng, M. C. Y.;
Cox, N. J.;
Bell, G. I.;
Laakso, M.

Publication type:

Article

Proteinuria and metabolic syndrome as predictors of cardiovascular death in non-diabetic and type 2 diabetic men and women.

Published in:

Diabetologia, 2006, v. 49, n. 1, p. 56, doi. 10.1007/s00125-005-0050-1

By:

Juutilainen, A.;
Lehto, S.;
Rönnemaa, T.;
Pyörälä, K.;
Laakso, M.

Publication type:

Article

A 100-kDa urinary protein is associated with insulin resistance in offspring of type 2 diabetic patients.

Published in:

Diabetologia, 2005, v. 48, n. 9, p. 1844, doi. 10.1007/s00125-005-1853-9

By:

Pätäri, A.;
Karhapää, P.;
Taipale, H.;
Salmenniemi, U.;
Ruotsalainen, E.;
Vanninen, P.;
Holthöfer, H.;
Laakso, M.

Publication type:

Article

Haplotypes of PPARGC1A are associated with glucose tolerance, body mass index and insulin sensitivity in offspring of patients with type 2 diabetes.

Published in:

Diabetologia, 2005, v. 48, n. 7, p. 1331, doi. 10.1007/s00125-005-1800-9

By:

Pihlajamäki, J.;
Kinnunen, M.;
Ruotsalainen, E.;
Salmenniemi, U.;
Vauhkonen, I.;
Kuulasmaa, T.;
Kainulainen, S.;
Laakso, M.

Publication type:

Article

Common polymorphisms of thePPAR-?2(Pro12Ala) andPGC-1a(Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial.

Published in:

Diabetologia, 2004, v. 47, n. 12, p. 2176, doi. 10.1007/s00125-004-1577-2

By:

Andrulionytè, L.;
Zacharova, J.;
Chiasson, J.-L.;
Laakso, M.

Publication type:

Article

Association between a deletion/insertion polymorphism in the α2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention Study α2B-adrenergic receptor gene and insulin secretion.

Published in:

Diabetologia, 2004, v. 47, n. 8, p. 1416, doi. 10.1007/s00125-004-1462-z

By:

Siitonen, N.;
Lindström, J.;
Eriksson, J.;
Valle, T. T.;
Hämäläinen, H.;
Ilanne-Parikka, P.;
Keinänen-Kiukaanniemi, S.;
Tuomilehto, J.;
Laakso, M.;
Uusitupa, M.

Publication type:

Article

Acarbose for the prevention of Type 2 diabetes, hypertension and cardiovascular disease in subjects with impaired glucose tolerance: facts and interpretations concerning the critical analysis of the STOP-NIDDM Trial data.

Published in:

Diabetologia, 2004, v. 47, n. 6, p. 969, doi. 10.1007/s00125-004-1409-4

By:

Chiasson, J.-L.;
Josse, R. G.;
Gomis, R.;
Hanefeld, M.;
Karasik, A.;
Laakso, M.

Publication type:

Article

Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes.: The Finnish Diabetes Prevention Study Insulin signalling genes and Type 2 diabetes

Published in:

Diabetologia, 2004, v. 47, n. 5, p. 871, doi. 10.1007/s00125-004-1395-6

By:

Laukkanen, O.;
Pihlajamäki, J.;
Lindström, J.;
Eriksson, J.;
Valle, T. T.;
Hämäläinen, H.;
Ilanne-Parikka, P.;
Keinänen-Kiukaanniemi, S.;
Tuomilehto, J.;
Uusitupa, M.;
Laakso, M.

Publication type:

Article

Characterisation of new K<sub>ATP</sub>-channel mutations associated with congenital hyperinsulinism in the Finnish population.

Published in:

2004

By:

Reimann, F.;
Huopio, H.;
Dabrowski, M.;
Proks, P.;
Gribble, F. M.;
Laakso, M.;
Otonkoski, T.;
Ashcroft, F. M.

Publication type:

Erratum

Characterisation of new K<sub>ATP</sub>-channel mutations associated with congenital hyperinsulinism in the Finnish population F. Reimann et al.: KATP-channel mutations causing CHI.

Published in:

Diabetologia, 2003, v. 46, n. 2, p. 241, doi. 10.1007/s00125-002-1014-3

By:

Reimann, F.;
Huopio, H.;
Dabrowski, M.;
Proks, P.;
Gribble, F. M.;
Laakso, M.;
Otonkoski, T.;
Ashcroft, F. M.

Publication type:

Article

Observation¶Effect of the Pro12Ala polymorphism of the PPAR-γ2 gene on long-term weight change in Finnish non-diabetic subjects.

Published in:

Diabetologia, 2001, v. 44, n. 7, p. 925

By:

Lindi, V.;
Sivenius, K.;
Niskanen, L.;
Laakso, M.;
Uusitupa, M. I. J.

Publication type:

Article

Cardiovascular risk factors clustering with endogenous hyperinsulinaemia predict death from coronary heart disease in patients with Type II diabetes.

Published in:

Diabetologia, 2000, v. 43, n. 2, p. 148, doi. 10.1007/s001250050023

By:

Lehto, S.;
Rönnemaa, T.;
Pyörälä, K.;
Laakso, M.

Publication type:

Article

Impaired insulin secretion in non-diabetic offspring of probands with latent autoimmune diabetes mellitus in adults.

Published in:

Diabetologia, 2000, v. 43, n. 1, p. 69, doi. 10.1007/s001259900177

By:

Vauhkonen, I.;
Niskanen, L.;
Knip, M.;
Ilonen, J.;
Vanninen, E.;
Kainulainen, S.;
Uusitupa, M.;
Laakso, M.

Publication type:

Article

Trigeminal neuralgia within the disease course of MS: Diagnostic and therapeutic implications from a multicenter cohort.

Published in:

Multiple Sclerosis Journal, 2025, v. 31, n. 5, p. 607, doi. 10.1177/13524585241309257

By:

Laakso, Sini M;
Oh, Jiwon;
Raufdeen, Fasna;
Jones, Ashley;
Reiskanen, Henri;
Feb, Ken;
Levit, Elle;
Solomon, Andrew J

Publication type:

Article

Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity.

Published in:

European Heart Journal, 2005, v. 26, n. 7, p. 650

By:

Malmberg, K.;
Rydén, L.;
Wedel, H.;
Birkeland, K.;
Bootsma, A.;
Dickstein, K.;
Efendic, S.;
Fisher, M.;
Hamsten, A.;
Herlitz, J.;
Hildebrandt, P.;
MacLeod, K.;
Laakso, M.;
Torp-Pedersen, C.;
Waldenström, A.

Publication type:

Article

Clonal Analysis of Regulatory T Cell Defect in Patients with Autoimmune Polyendocrine Syndrome Type 1 Suggests Intrathymic Impairment.

Published in:

Scandinavian Journal of Immunology, 2017, v. 86, n. 4, p. 221, doi. 10.1111/sji.12586

By:

Koivula, T.‐T.;
Laakso, S. M.;
Niemi, H. J.;
Kekäläinen, E.;
Laine, P.;
Paulin, L.;
Auvinen, P.;
Arstila, T. P.

Publication type:

Article