Works by Laakso, Markku

Results: 365

Microbiota-Related Metabolites and the Risk of Type 2 Diabetes.

Published in:

2020

By:

Vangipurapu, Jagadish;
Silva, Lilian Fernandes;
Kuulasmaa, Teemu;
Smith, Ulf;
Markku Laakso;
Fernandes Silva, Lilian;
Laakso, Markku

Publication type:

journal article

LMNA Mutation c.917T>G (p.L306R) Leads to Deleterious Hyper-Assembly of Lamin A/C and Associates with Severe Right Ventricular Cardiomyopathy and Premature Aging.

Published in:

Human Mutation, 2015, v. 36, n. 7, p. 694, doi. 10.1002/humu.22793

By:

Alastalo, Tero‐Pekka;
West, Gun;
Li, Song‐Ping;
Keinänen, Anni;
Helenius, Mikko;
Tyni, Tiina;
Lapatto, Risto;
Turanlahti, Maila;
Heikkilä, Päivi;
Kääriäinen, Helena;
Laakso, Markku;
Mauermann, Monika;
Herrmann, Harald;
Pihkala, Jaana;
Taimen, Pekka

Publication type:

Article

The activation of hepatic and muscle polyamine catabolism improves glucose homeostasis.

Published in:

Amino Acids, 2012, v. 42, n. 2/3, p. 427, doi. 10.1007/s00726-011-1013-0

By:

Koponen, Taina;
Cerrada-Gimenez, Marc;
Pirinen, Eija;
Hohtola, Esa;
Paananen, Jussi;
Vuohelainen, Susanna;
Tusa, Maija;
Pirnes-Karhu, Sini;
Heikkinen, Sami;
Virkamäki, Antti;
Uimari, Anne;
Alhonen, Leena;
Laakso, Markku

Publication type:

Article

Activated polyamine catabolism leads to low cholesterol levels by enhancing bile acid synthesis.

Published in:

Amino Acids, 2010, v. 38, n. 2, p. 549, doi. 10.1007/s00726-009-0416-7

By:

Pirinen, Eija;
Gylling, Helena;
Itkonen, Paula;
Yaluri, Nagendra;
Heikkinen, Sami;
Pietilä, Marko;
Kuulasmaa, Teemu;
Tusa, Maija;
Cerrada-Gimenez, Marc;
Pihlajamäki, Jussi;
Alhonen, Leena;
Jänne, Juhani;
Miettinen, Tatu A.;
Laakso, Markku

Publication type:

Article

INTERLEUKIN-6 PROMOTER POLYMORPHISM AND LATE-ONSET ALZHEIMER's DISEASE IN THE FINNISH POPULATION.

Published in:

Journal of Neurogenetics, 2005, v. 19, n. 3/4, p. 155, doi. 10.1080/01677060600569721

By:

Koivisto, Anne M.;
Helisalmi, Seppo;
Pihlajamäki, Jussi;
Moilanen, Leena;
Kuusisto, Johanna;
Laakso, Markku;
Hiltunen, Mikko;
Keijo, Koivisto;
Hänninen, Tuomo;
Helkala, Eeva-Liisa;
Kervinen, Kari;
kesäniemi, Y. Antero;
Soininen, Hilkka

Publication type:

Article

Decreased plasma C‐reactive protein levels in APOE ε4 allele carriers.

Published in:

Annals of Clinical & Translational Neurology, 2018, v. 5, n. 10, p. 1229, doi. 10.1002/acn3.639

By:

Martiskainen, Henna;
Stančáková, Alena;
Kuusisto, Johanna;
Laakso, Markku;
Takalo, Mari;
Marttinen, Mikael;
Natunen, Teemu;
Hiltunen, Mikko;
Solomon, Alina;
Kivipelto, Miia;
Herukka, Sanna‐Kaisa;
Soininen, Hilkka;
Haapasalo, Annakaisa

Publication type:

Article

Functional Variant in the GCKR Gene Affects Lactate Levels Differentially in the Fasting State and During Hyperglycemia.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34501-9

By:

López Rodríguez, Maykel;
Fernandes Silva, Lilian;
Vangipurapu, Jagadish;
Modi, Shalem;
Kuusisto, Johanna;
Kaikkonen, Minna U.;
Laakso, Markku

Publication type:

Article

Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 3, p. 174, doi. 10.3390/metabo14030174

By:

Mirzaei, Sahereh;
DeVon, Holli A.;
Cantor, Rita M.;
Cupido, Arjen J.;
Pan, Calvin;
Ha, Sung Min;
Silva, Lilian Fernandes;
Hilser, James R.;
Hartiala, Jaana;
Allayee, Hooman;
Rey, Federico E.;
Laakso, Markku;
Lusis, Aldons J.

Publication type:

Article

Plasma Metabolite Signatures in Male Carriers of Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 2, p. 267, doi. 10.3390/metabo13020267

By:

Fernandes Silva, Lilian;
Vangipurapu, Jagadish;
Oravilahti, Anniina;
Männistö, Ville;
Laakso, Markku

Publication type:

Article

Effects of SLCO1B1 Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 12, p. 1159, doi. 10.3390/metabo12121159

By:

Fernandes Silva, Lilian;
Ravi, Rowmika;
Vangipurapu, Jagadish;
Oravilahti, Anniina;
Laakso, Markku

Publication type:

Article

Metabolite Signature of Simvastatin Treatment Involves Multiple Metabolic Pathways.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 8, p. 753, doi. 10.3390/metabo12080753

By:

Fernandes Silva, Lilian;
Ravi, Rowmika;
Vangipurapu, Jagadish;
Laakso, Markku

Publication type:

Article

Metabolite Signature in the Carriers of Pathogenic Genetic Variants for Cardiomyopathy: A Population-Based METSIM Study.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 5, p. 437, doi. 10.3390/metabo12050437

By:

Ravi, Rowmika;
Fernandes Silva, Lilian;
Vangipurapu, Jagadish;
Maria, Maleeha;
Raivo, Joose;
Helisalmi, Seppo;
Laakso, Markku

Publication type:

Article

Metabolite Signature of Physical Activity and the Risk of Type 2 Diabetes in 7271 Men.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 1, p. 69, doi. 10.3390/metabo12010069

By:

Kemppainen, Susanna Maria;
Silva, Lilian Fernandes;
Lankinen, Maria Anneli;
Schwab, Ursula;
Laakso, Markku

Publication type:

Article

The "Common Soil Hypothesis" Revisited—Risk Factors for Type 2 Diabetes and Cardiovascular Disease.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 10, p. 691, doi. 10.3390/metabo11100691

By:

Fernandes Silva, Lilian;
Vangipurapu, Jagadish;
Laakso, Markku

Publication type:

Article

Association Analysis and Meta-Analysis of Multi-Allelic Variants for Large-Scale Sequence Data.

Published in:

Genes, 2020, v. 11, n. 5, p. 586, doi. 10.3390/genes11050586

By:

Jiang, Yu;
Chen, Sai;
Wang, Xingyan;
Liu, Mengzhen;
Iacono, William G.;
Hewitt, John K.;
Hokanson, John E.;
Krauter, Kenneth;
Laakso, Markku;
Li, Kevin W.;
Lutz, Sharon M.;
McGue, Matthew;
Pandit, Anita;
Zajac, Gregory J.M.;
Boehnke, Michael;
Abecasis, Goncalo R.;
Vrieze, Scott I.;
Jiang, Bibo;
Zhan, Xiaowei;
Liu, Dajiang J.

Publication type:

Article

PNPLA3 Genotype and Dietary Fat Modify Concentrations of Plasma and Fecal Short Chain Fatty Acids and Plasma Branched-Chain Amino Acids.

Published in:

Nutrients, 2024, v. 16, n. 2, p. 261, doi. 10.3390/nu16020261

By:

Tauriainen, Milla-Maria;
Csader, Susanne;
Lankinen, Maria;
Lo, Kwun Kwan;
Chen, Congjia;
Lahtinen, Olli;
El-Nezamy, Hani;
Laakso, Markku;
Schwab, Ursula

Publication type:

Article

Genetic influences contributing to LDL particle size in familial combined hyperlipidaemia.

Published in:

European Journal of Human Genetics, 2002, v. 10, n. 9, p. 547, doi. 10.1038/sj.ejhg.5200844

By:

Vakkilainen, Juha;
Pajukanta, Paivi;
Cantor, Rita M.;
Nuotio, Ilpo O.;
Lahdenpera, Sanni;
Ylitalo, Kati;
Pihlajamaki, Jussi;
Kovanen, Petri T.;
Laakso, Markku;
Viikari, Jorma S.A.;
Peltonen, Leena;
Taskinen, Marja-Riitta

Publication type:

Article

Interactions between genetic variation and cellular environment in skeletal muscle gene expression.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0195788

By:

Taylor, D. Leland;
Knowles, David A.;
Scott, Laura J.;
Ramirez, Andrea H.;
Casale, Francesco Paolo;
Wolford, Brooke N.;
Guan, Li;
Varshney, Arushi;
Albanus, Ricardo D’Oliveira;
Parker, Stephen C. J.;
Narisu, Narisu;
Chines, Peter S.;
Erdos, Michael R.;
Welch, Ryan P.;
Kinnunen, Leena;
Saramies, Jouko;
Sundvall, Jouko;
Lakka, Timo A.;
Laakso, Markku;
Tuomilehto, Jaakko

Publication type:

Article

Adipose Co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes.

Published in:

BMC Medical Genomics, 2012, v. 5, n. 1, p. 61, doi. 10.1186/1755-8794-5-61

By:

Haas, Blake E.;
Horvath, Steve;
Pietil„inen, Kirsi H.;
Cantor, Rita M.;
Nikkola, Elina;
Weissglas-Volkov, Daphna;
Rissanen, Aila;
Civelek, Mete;
Cruz-Bautista, Ivette;
Riba, Laura;
Kuusisto, Johanna;
Kaprio, Jaakko;
Tusie-Luna, Teresa;
Laakso, Markku;
Aguilar-Salinas, Carlos A.;
Pajukanta, P„ivi

Publication type:

Article

Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels.

Published in:

Nature Medicine, 1998, v. 4, n. 12, p. 1434, doi. 10.1038/4027

By:

Karvonen, Matti K.;
Pesonen, Ullamari;
Koulu, Markku;
Niskanen, Leo;
Laakso, Markku;
Rissanen, Aila;
Dekker, Jacqueline M.;
Hart, Leen M ´t;
Valve, Raisa;
Uusitupa, Matti I.J.

Publication type:

Article

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).

Published in:

Nature Genetics, 2004, v. 36, n. 4, p. 371, doi. 10.1038/ng1320

By:

Pajukanta, Päivi;
Lilja, Heidi E.;
Sinsheimer, Janet S.;
Cantor, Rita M.;
Gentile, Massimiliano;
Lusis, Aldons J.;
Duan, Xiaoqun Joyce;
Soro-Paavonen, Aino;
Naukkarinen, Jussi;
Saarela, Janna;
Laakso, Markku;
Ehnholm, Christian;
Taskinen, Marja-Riitta;
Peltonen, Leena

Publication type:

Article

A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity.

Published in:

Nature Genetics, 1998, v. 20, n. 3, p. 284, doi. 10.1038/3099

By:

Deeb, Samir S.;
Fajas, Lluis;
Nemoto, Masami;
Pihlajamäki, Jussi;
Mykkänen, Leena;
Kuusisto, Johanna;
Laakso, Markku;
Fujimoto, Wilfred;
Auwerx, Johan

Publication type:

Article

Association of Common Genetic Variation in the FOXO1 Gene with β-Cell Dysfunction, Impaired Glucose Tolerance, and Type 2 Diabetes.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2009, v. 94, n. 4, p. 1353, doi. 10.1210/jc.2008-1048

By:

Müssig, Karsten;
Staiger, Harald;
Machicao, Fausto;
Stančáková, Alena;
Kuusisto, Johanna;
Laakso, Markku;
Thamer, Claus;
Machann, Jürgen;
Schick, Fritz;
Claussen, Claus D.;
Stefan, Norbert;
Fritsche, Andreas;
Häring, Hans-Ulrich

Publication type:

Article

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance.

Published in:

2008

By:

Stancáková, Alena;
Pihlajamäki, Jussi;
Kuusisto, Johanna;
Stefan, Norbert;
Fritsche, Andreas;
Häring, Hans;
Andreozzi, Francesco;
Succurro, Elena;
Sesti, Giorgio;
Boesgaard, Trine Welløv;
Hansen, Torben;
Pedersen, Oluf;
Jansson, Per Anders;
Hammarstedt, Ann;
Smith, Ulf;
Laakso, Markku;
EUGENE2 Consortium

Publication type:

journal article

Variations in PPARD Determine the Change in Body Composition during Lifestyle Intervention: A Whole-Body Magnetic Resonance Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2008, v. 93, n. 4, p. 1497, doi. 10.1210/jc.2007-1209

By:

Thamer, Claus;
Machann, Jürgen;
Stefan, Norbert;
Schäfer, Silke A.;
Machicao, Fausto;
Staiger, Harald;
Laakso, Markku;
Böttcher, Michael;
Claussen, Claus;
Schick, Fritz;
Fritsche, Andreas;
Haring, Hans-Ulrich

Publication type:

Article

Genetic Variations in PPARD and PPARGC1A Determine Mitochondrial Function and Change in Aerobic Physical Fitness and Insulin Sensitivity during Lifestyle Intervention.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2007, v. 92, n. 5, p. 1827, doi. 10.1210/jc.2006-1785

By:

Stefan, Norbert;
Thamer, Claus;
Staiger, Harald;
Machicao, Fausto;
Machann, Jürgen;
Schick, Fritz;
Venter, Christian;
Niess, Andreas;
Laakso, Markku;
Fritsche, Andreas;
Häring, Hans-Ulrich

Publication type:

Article

Single Nucleotide Polymorphisms of the Melanocortin-3 Receptor Gene Are Associated with Substrate Oxidation and First-Phase Insulin Secretion in Offspring of Type 2 Diabetic Subjects.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2007, v. 92, n. 3, p. 1112, doi. 10.1210/jc.2006-1201

By:

Rutanen, Jarno;
Pihlajamäki, Jussi;
Vänttinen, Markku;
Salmenniemi, Urpu;
Ruotsalainen, Eija;
Kuulasmaa, Teemu;
Kainulainen, Sakari;
Laakso, Markku

Publication type:

Article

Visfatin Is an Adipokine, But It Is Not Regulated by Thiazolidinediones.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 3, p. 1181, doi. 10.1210/jc.2005-1395

By:

Hammarstedt, Ann;
Pihlajamäki, Jussi;
Sopasakis, Victoria Rotter;
Gogg, Silvia;
Jansson, Per-Anders;
Laakso, Markku;
Smith, Ulf

Publication type:

Article

Association of Adiponectin Level and Variants in the Adiponectin Gene with Glucose Metabolism, Energy Expenditure, and Cytokines in Offspring of Type 2 Diabetic Patients.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 7, p. 4216, doi. 10.1210/jc.2004-2289

By:

Salmenniemi, Urpu;
Zacharova, Jelena;
Ruotsalainen, Eija;
Vauhkonen, Ilkka;
Pihlajamäki, Jussi;
Kainulainen, Sakari;
Punnonen, Kari;
Laakso, Markku

Publication type:

Article

The Effect of the Ala12 Allele of the Peroxisome Proliferator-Activated Receptor-γ2 Gene on Skeletal Muscle Glucose Uptake Depends on Obesity: A Positron Emission Tomography Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 7, p. 4249, doi. 10.1210/jc.2005-0101

By:

Vänttinen, Markku;
Nuutila, Pirjo;
Pihlajamäki, Jussi;
Hällsten, Kirsti;
Virtanen, Kirsi A.;
Lautamäki, Riikka;
Peltoniemi, Pauliina;
Kemppainen, Jukka;
Takala, Teemu;
Viljanen, Antti P. M.;
Knuuti, Juhani;
Laakso, Markku

Publication type:

Article

Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) Genes Predict the Conversion from Impaired Glucose Tolerance to Type 2 Diabetes. The Finnish Diabetes Prevention Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 12, p. 6286, doi. 10.1210/jc.2004-1204

By:

LAUKKANEN, OLLI;
PIHLAJAMÄKI, JUSSI;
LINDSTRÖM, JAANA;
ERIKSSON, JOHAN;
VALLE, TIMO T.;
HÄMÄLÄINEN, HELENA;
ILANNE-PARIKKA, PIRJO;
NEN-KIUKAANNIEMI, SIRKKA KEINÄ;
TUOMILEHTO, JAAKKO;
UUSITUPA, MATTI;
LAAKSO, MARKKU

Publication type:

Article

Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study.

Published in:

2004

By:

Laukkanen, Olli;
Pihlajamäki, Jussi;
Lindström, Jaana;
Eriksson, Johan;
Valle, Timo T;
Hämäläinen, Helena;
Ilanne-Parikka, Pirjo;
Keinänen-Kiukaanniemi, Sirkka;
Tuomilehto, Jaakko;
Uusitupa, Matti;
Laakso, Markku;
Finnish Diabetes Prevention Study Group

Publication type:

journal article

Ala12 Ala Genotype of the Peroxisome Proliferator-Activated Receptor γ2 Protects against Atherosclerosis.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 9, p. 4238, doi. 10.1210/jc.2003-032120

By:

TEMELKOVA-KURKTSCHIEV, THEODORA;
HANEFELD, MARKOLF;
CHINETTI, GIULIA;
ZAWADZKI, CHRISTOPHE;
HAULON, STEPHAN;
KUBASZEK, AGATA;
KOEHLER, CARSTA;
LEONHARDT, WOLFGANG;
STAELS, BART;
LAAKSO, MARKKU

Publication type:

Article

The G-250A Promoter Polymorphism of the Hepatic Lipase Gene Predicts the Conversion from Impaired Glucose Tolerance to Type 2 Diabetes Mellitus: The Finnish Diabetes Prevention Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 5, p. 2019, doi. 10.1210/jc.2003-031325

By:

TODOROVA, BORYANA;
KUBASZEK, AGATA;
PIHLAJAMÄKI, JUSSI;
LINDSTRÖM, JAANA;
ERIKSSON, JOHAN;
VALLE, TIMO T.;
HÄMÄLÄINEN, HELENA;
ILANNE-PARIKKA, PIRJO;
KEINÄNEN-KIUKAANNIEMI, SIRKKA;
TUOMILEHTO, JAAKKO;
UUSITUPA, MATTI;
LAAKSO, MARKKU

Publication type:

Article

The Association of the K121Q Polymorphism of the Plasma Cell Glycoprotein-1 Gene with Type 2 Diabetes and Hypertension Depends on Size at Birth.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 5, p. 2044, doi. 10.1210/jc.2003-031350

By:

KUBASZEK, AGATA;
MARKKANEN, ANU;
ERIKSSON, JOHAN G.;
FORSEN, TOM;
OSMOND, CLIVE;
BARKER, DAVID J. P.;
LAAKSO, MARKKU

Publication type:

Article

Leucine 7 to Proline 7 Polymorphism in the Neuropeptide Y Gene Is Associated with Enhanced Carotid Atherosclerosis in Elderly Patients with Type 2 Diabetes and Control Subjects.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2000, v. 85, n. 6, p. 2266, doi. 10.1210/jcem.85.6.6633

By:

NISKANEN, LEO;
KARVONEN, MATTI K.;
VALVE, RAISA;
KOULU, MARKKU;
PESONEN, ULLAMARI;
MERCURI, MICHELE;
RAURAMAA, RAINER;
TÖYRY, JARI;
LAAKSO, MARKKU;
UUSITUPA, MATTI I. J.

Publication type:

Article

Identification of a Three-Amino Acid Deletion in the α2B-Adrenergic Receptor That Is Associated with Reduced Basal Metabolic Rate in Obese Subjects.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 7, p. 2429, doi. 10.1210/jcem.84.7.5818

By:

HEINONEN, PAULA;
KOULU, MARKKU;
PESONEN, ULLAMARI;
KARVONEN, MATTI K.;
RISSANEN, AILA;
LAAKSO, MARKKU;
VALVE, RAISA

Publication type:

Article

Independent Influence of Age on Basal Insulin Secretion in Nondiabetic Humans.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 3, p. 863, doi. 10.1210/jcem.84.3.5542

By:

IOZZO, PATRICIA;
BECK-NIELSEN, HENNING;
LAAKSO, MARKKU;
SMITH, ULF;
YKI-JÄRVINEN, HANNELE;
FERRANNINI, ELE

Publication type:

Article

Additive Effects of the Mutations in theβ 3-Adrenergic Receptor and Uncoupling Protein-1 Genes on Weight Loss and Weight Maintenance in Finnish Women1.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1998, v. 83, n. 12, p. 4246, doi. 10.1210/jcem.83.12.5339

By:

FOGELHOLM, MIKAEL;
VALVE, RAISA;
KUKKONEN-HARJULA, KATRIINA;
NENONEN, ARJA;
HAKKARAINEN, VIRPI;
LAAKSO, MARKKU;
UUSITUPA, MATTI

Publication type:

Article

Identification of New Sequence Variants in the Leptin Gene.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1998, v. 83, n. 9, p. 3239, doi. 10.1210/jcem.83.9.5135

By:

KARVONEN, MATTI K.;
PESONEN, ULLAMARI;
HEINONEN, PAULA;
LAAKSO, MARKKU;
RISSANEN, AILA;
NAUKKARINEN, HANNU;
VALVE, RAISA;
UUSITUPA, MATTI I. J.;
KOULU, MARKKU

Publication type:

Article

Variants in the Human Intestinal Fatty Acid Binding Protein 2 Gene in Obese Subjects.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 8, p. 2629, doi. 10.1210/jc.82.8.2629

By:

SIPILÄINEN, RAISA;
UUSITUPA, MATTI;
HEIKKINEN, SAMI;
RISSANEN, AILA;
LAAKSO, MARKKU

Publication type:

Article

Low Levels of Sex Hormone-Binding Globulin and Testosterone Are Associated with Smaller, Denser Low Density Lipoprotein in Normoglycemic Men.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1996, v. 81, n. 10, p. 3697, doi. 10.1210/jc.81.10.3697

By:

HAFFNER, STEVEN M.;
LAAKSO, MARKKU;
MIETTINEN, HEIKKI;
MYKKÄNEN, LEENA;
KARHAPÄÄ, PAULI;
RAINWATER, DAVID L.

Publication type:

Article

Advances in Metabolomics: A Comprehensive Review of Type 2 Diabetes and Cardiovascular Disease Interactions.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 8, p. 3572, doi. 10.3390/ijms26083572

By:

Fernandes Silva, Lilian;
Laakso, Markku

Publication type:

Article

Metabolomics, Genetics, and Environmental Factors: Intersecting Paths in Abdominal Aortic Aneurysm.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1498, doi. 10.3390/ijms26041498

By:

Fernandes Silva, Lilian;
Vangipurapu, Jagadish;
Oravilahti, Anniina;
Lusis, Aldons Jake;
Laakso, Markku

Publication type:

Article

Prognostic role of pro- and anti-inflammatory cytokines and their polymorphisms in acute decompensated heart failure

Published in:

European Journal of Heart Failure, 2008, v. 10, n. 4, p. 396, doi. 10.1016/j.ejheart.2008.02.008

By:

Miettinen, Kati H.;
Lassus, Johan;
Harjola, Veli-Pekka;
Siirilä-Waris, Krista;
Melin, John;
Punnonen, Kari R.;
Nieminen, Markku S.;
Laakso, Markku;
Peuhkurinen, Keijo J.

Publication type:

Article

Two novel mutations in the β-myosin heavy chain gene associated with dilated cardiomyopathy

Published in:

European Journal of Heart Failure, 2004, v. 6, n. 7, p. 861, doi. 10.1016/j.ejheart.2004.04.017

By:

Kärkkäinen, Satu;
Heliö, Tiina;
Jääskeläinen, Pertti;
Miettinen, Raija;
Tuomainen, Petri;
Ylitalo, Kari;
Kaartinen, Maija;
Reissell, Eeva;
Toivonen, Lauri;
Nieminen, Markku S.;
Kuusisto, Johanna;
Laakso, Markku;
Peuhkurinen, Keijo

Publication type:

Article

Partial hexokinase II knockout results in acute ischemia–reperfusion damage in skeletal muscle of male, but not female, mice.

Published in:

Pflügers Archiv: European Journal of Physiology, 2010, v. 459, n. 5, p. 705, doi. 10.1007/s00424-010-0787-3

By:

Smeele, Kirsten M.;
Eerbeek, Otto;
Koeman, Anneke;
Bezemer, Rick;
Ince, Can;
Heikkinen, Sami;
Laakso, Markku;
de Haan, Arnold;
Schaart, Gert;
Drost, Maarten R.;
Hollmann, Markus W.;
Zuurbier, Coert J.

Publication type:

Article

Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood.

Published in:

Diabetologia, 2023, v. 66, n. 8, p. 1472, doi. 10.1007/s00125-023-05923-6

By:

Hawkes, Gareth;
Beaumont, Robin N.;
Tyrrell, Jessica;
Power, Grace M.;
Wood, Andrew;
Laakso, Markku;
Fernandes Silva, Lilian;
Boehnke, Michael;
Yin, Xianyong;
Richardson, Tom G.;
Smith, George Davey;
Frayling, Timothy M.

Publication type:

Article

Correction to: The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study.

Published in:

2021

By:

Koivula, Robert W.;
Atabaki-Pasdar, Naeimeh;
Giordano, Giuseppe N.;
White, Tom;
Adamski, Jerzy;
Bell, Jimmy D.;
Beulens, Joline;
Brage, Søren;
Brunak, Søren;
De Masi, Federico;
Dermitzakis, Emmanouil T.;
Forgie, Ian M.;
Frost, Gary;
Hansen, Torben;
Hansen, Tue H.;
Hattersley, Andrew;
Kokkola, Tarja;
Kurbasic, Azra;
Laakso, Markku;
Mari, Andrea

Publication type:

Correction Notice

The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study.

Published in:

Diabetologia, 2020, v. 63, n. 4, p. 744, doi. 10.1007/s00125-019-05083-6

By:

Koivula, Robert W.;
Atabaki-Pasdar, Naeimeh;
Giordano, Giuseppe N.;
White, Tom;
Adamski, Jerzy;
Bell, Jimmy D.;
Beulens, Joline;
Brage, Søren;
Brunak, Søren;
De Masi, Federico;
Dermitzakis, Emmanouil T.;
Forgie, Ian M.;
Frost, Gary;
Hansen, Torben;
Hansen, Tue H.;
Hattersley, Andrew;
Kokkola, Tarja;
Kurbasic, Azra;
Laakso, Markku;
Mari, Andrea

Publication type:

Article