Works matching AU La Gruta, Nicole L.

Results: 29

T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 480, doi. 10.1038/nsmb.2817

By:

Petersen, Jan;
Montserrat, Veronica;
Mujico, Jorge R;
Loh, Khai Lee;
Beringer, Dennis X;
van Lummel, Menno;
Thompson, Allan;
Mearin, M Luisa;
Schweizer, Joachim;
Kooy-Winkelaar, Yvonne;
van Bergen, Jeroen;
Drijfhout, Jan W;
Kan, Wan-Ting;
La Gruta, Nicole L;
Anderson, Robert P;
Reid, Hugh H;
Koning, Frits;
Rossjohn, Jamie

Publication type:

Article

The clock is ticking: the impact of ageing on T cell metabolism.

Published in:

Clinical & Translational Immunology, 2019, v. 8, n. 11, p. 1, doi. 10.1002/cti2.1091

By:

Quinn, Kylie M;
Palchaudhuri, Riya;
Palmer, Clovis S;
La Gruta, Nicole L

Publication type:

Article

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations.

Published in:

Nature Immunology, 2005, v. 6, n. 4, p. 382, doi. 10.1038/ni1175

By:

Turner, Stephen J.;
Kedzierska, Katherine;
Komodromou, Helen;
La Gruta, Nicole L.;
Dunstone, Michelle A.;
Webb, Andrew I.;
Webby, Richard;
Walden, Helen;
Xie, Wiedong;
McCluskey, James;
Purcell, Anthony W.;
Rossjohn, Jamie;
Doherty, Peter C.

Publication type:

Article

T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25404-x

By:

Tran, Mai T.;
Faridi, Pouya;
Lim, Jia Jia;
Ting, Yi Tian;
Onwukwe, Goodluck;
Bhattacharjee, Pushpak;
Jones, Claerwen M.;
Tresoldi, Eleonora;
Cameron, Fergus J.;
La Gruta, Nicole L.;
Purcell, Anthony W.;
Mannering, Stuart I.;
Rossjohn, Jamie;
Reid, Hugh H.

Publication type:

Article

Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity.

Published in:

European Journal of Immunology, 2012, v. 42, n. 7, p. 1744, doi. 10.1002/eji.201142211

By:

Seah, Shirley G.K.;
Carrington, Emma M.;
Ng, Wy C.;
Belz, Gabrielle T.;
Brady, Jamie L.;
Sutherland, Robyn M.;
Hancock, Manuela S.;
La Gruta, Nicole L.;
Brown, Lorena E.;
Turner, Stephen J.;
Zhan, Yifan;
Lew, Andrew M.

Publication type:

Article

The linear range for accurately quantifying antigen-specific T-cell frequencies by tetramer staining during natural immune responses.

Published in:

European Journal of Immunology, 2011, v. 41, n. 5, p. 1499, doi. 10.1002/eji.201141399

By:

Seah, Shirley G. K.;
Sutherland, Robyn M.;
La Gruta, Nicole L.;
Brown, Lorena E.;
Carrington, Emma M.;
Belz, Gabrielle T.;
Brady, Jamie L.;
Turner, Stephen J.;
Zhan, Yifan;
Lew, Andrew M.

Publication type:

Article

Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32692-4

By:

Szeto, Christopher;
Zareie, Pirooz;
Wirasinha, Rushika C.;
Zhang, Justin B.;
Nguyen, Andrea T.;
Riboldi-Tunnicliffe, Alan;
La Gruta, Nicole L.;
Gras, Stephanie;
Daley, Stephen R.

Publication type:

Article

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion.

Published in:

2010

By:

La Gruta, Nicole L.;
Rothwell, William T.;
Cukalac, Tania;
Swan, Natasha G.;
Valkenburg, Sophie A.;
Kedzierska, Katherine;
Thomas, Paul G.;
Doherty, Peter C.;
Turner, Stephen J.

Publication type:

journal article

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184732

By:

Quinn, Kylie M.;
Kan, Wan-Ting;
Watson, Katherine A.;
Liddicoat, Brian J.;
Swan, Natasha G.;
McQuilten, Hayley;
Denton, Alice E.;
Li, Jasmine;
Chen, Weisan;
Brown, Lorena E.;
Jackson, David C.;
Reading, Patrick C.;
Doherty, Peter C.;
Kedzierska, Katherine;
Kedzierski, Lukasz;
Turner, Stephen J.;
La Gruta, Nicole L.

Publication type:

Article

Evaluation of inflammation and follicle depletion during ovarian ageing in mice.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79488-4

By:

Lliberos, Carolina;
Liew, Seng H.;
Zareie, Pirooz;
La Gruta, Nicole L.;
Mansell, Ashley;
Hutt, Karla

Publication type:

Article

Publisher Correction: Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality.

Published in:

2020

By:

Quinn, Kylie M.;
Hussain, Tabinda;
Kraus, Felix;
Formosa, Luke E.;
Lam, Wai K.;
Dagley, Michael J.;
Saunders, Eleanor C.;
Assmus, Lisa M.;
Wynne-Jones, Erica;
Loh, Liyen;
van de Sandt, Carolien E.;
Cooper, Lucy;
Good-Jacobson, Kim L.;
Kedzierska, Katherine;
Mackay, Laura K.;
McConville, Malcolm J.;
Ramm, Georg;
Ryan, Michael T.;
La Gruta, Nicole L.

Publication type:

Correction Notice

Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16633-7

By:

Quinn, Kylie M.;
Hussain, Tabinda;
Kraus, Felix;
Formosa, Luke E.;
Lam, Wai K.;
Dagley, Michael J.;
Saunders, Eleanor C.;
Assmus, Lisa M.;
Wynne-Jones, Erica;
Loh, Liyen;
van de Sandt, Carolien E.;
Cooper, Lucy;
Good-Jacobson, Kim L.;
Kedzierska, Katherine;
Mackay, Laura K.;
McConville, Malcolm J.;
Ramm, Georg;
Ryan, Michael T.;
La Gruta, Nicole L.

Publication type:

Article

CD4+CD8β+ double‐positive T cells in skin‐draining lymph nodes respond to inflammatory signals from the skin.

Published in:

Journal of Leukocyte Biology, 2017, v. 102, n. 3, p. 837, doi. 10.1189/jlb.1AB0217-065R

By:

Overgaard, Nana H.;
Cruz, Jazmina L.;
Bridge, Jennifer A.;
Nel, Hendrik J.;
Frazer, Ian H.;
La Gruta, Nicole L.;
Blumenthal, Antje;
Steptoe, Raymond J.;
Wells, James W.

Publication type:

Article

Establishment and recall of CD8+ T-cell memory in a model of localized transient infection.

Published in:

Immunological Reviews, 2006, v. 211, n. 1, p. 133, doi. 10.1111/j.0105-2896.2006.00386.x

By:

Kedzierska, Katherine;
La Gruta, Nicole L.;
J. Turner, Stephen;
Doherty, Peter C.

Publication type:

Article

A question of self-preservation: immunopathology in influenza virus infection.

Published in:

Immunology & Cell Biology, 2007, v. 85, n. 2, p. 85, doi. 10.1038/sj.icb.7100026

By:

La Gruta, Nicole L.;
Kedzierska, Katherine;
Stambas, John;
Doherty, Peter C.

Publication type:

Article

A naturally selected αβ T cell receptor binds HLA-DQ2 molecules without co-contacting the presented peptide.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58690-w

By:

Lim, Jia Jia;
Jones, Claerwen M.;
Loh, Tiing Jen;
Dao, Hien Thy;
Tran, Mai T.;
Tye-Din, Jason A.;
La Gruta, Nicole L.;
Rossjohn, Jamie

Publication type:

Article

Direct recognition of an intact foreign protein by an αβ T cell receptor.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51897-3

By:

Almeida, Catarina F.;
Gully, Benjamin S.;
Jones, Claerwen M.;
Kedzierski, Lukasz;
Gunasinghe, Sachith D.;
Rice, Michael T.;
Berry, Richard;
Gherardin, Nicholas A.;
Nguyen, Trang T.;
Mok, Yee-Foong;
Reijneveld, Josephine F.;
Moody, D. Branch;
Van Rhijn, Ildiko;
La Gruta, Nicole L.;
Uldrich, Adam P.;
Rossjohn, Jamie;
Godfrey, Dale I.

Publication type:

Article

The Role of Natural Killer Cells in the Induction of Autoimmune Gastritis.

Published in:

Autoimmunity, 2001, v. 34, n. 2, p. 147, doi. 10.3109/08916930109001962

By:

La Gruta, Nicole L.;
Van Driel, Ian R.;
Toh, Ban Hock;
Gleeson, Paul A.

Publication type:

Article

Paired TCRαβ analysis of virus-specific CD8+ T cells exposes diversity in a previously defined ‘narrow’ repertoire.

Published in:

Immunology & Cell Biology, 2015, v. 93, n. 9, p. 804, doi. 10.1038/icb.2015.44

By:

Cukalac, Tania;
Wan-Ting Kan;
Dash, Pradyot;
Jing Guan;
Quinn, Kylie M;
Gras, Stephanie;
Thomas, Paul G;
La Gruta, Nicole L

Publication type:

Article

IL-18, but not IL-12, is required for optimal cytokine production by influenza virus-specific CD8.

Published in:

European Journal of Immunology, 2007, v. 37, n. 2, p. 368, doi. 10.1002/eji.200636766

By:

Denton, Alice E.;
Doherty, Peter C.;
Turner, Stephen J.;
La Gruta, Nicole L.

Publication type:

Article

A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8.

Published in:

European Journal of Immunology, 2006, v. 36, n. 11, p. 2951, doi. 10.1002/eji.200636390

By:

La Gruta, Nicole L.;
Doherty, Peter C.;
Turner, Stephen J.

Publication type:

Article

Peripheral T cell expansion in lymphopenic mice results in a restricted T cell repertoire.

Published in:

European Journal of Immunology, 2000, v. 30, n. 12, p. 3380, doi. 10.1002/1521-4141(2000012)30:12<3380::AID-IMMU3380>3.0.CO;2-P

By:

Gruta, Nicole L. La;
Driel, Ian R. van;
Gleeson, Paul A.

Publication type:

Article

PTPN2 attenuates T-cell lymphopenia-induced proliferation.

Published in:

Nature Communications, 2014, v. 5, n. 1, p. 3073, doi. 10.1038/ncomms4073

By:

Wiede, Florian;
La Gruta, Nicole L.;
Tiganis, Tony

Publication type:

Article

Sizing up the key determinants of the CD8(+) T cell response.

Published in:

2015

By:

Tscharke, David C.;
Croft, Nathan P.;
Doherty, Peter C.;
La Gruta, Nicole L.

Publication type:

journal article

Immune Responses to Circulating and Vaccine Viral Strains in HIV-Infected and Uninfected Children and Youth Who Received the 2013/2014 Quadrivalent Live-Attenuated Influenza Vaccine.

Published in:

Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00142

By:

Weinberg, Adriana;
Curtis, Donna;
Ning, Mariangeli Freitas;
Claypool, David Jeremy;
Jalbert, Emilie;
Patterson, Julie;
Frank, Daniel N.;
Ir, Diana;
Armon, Carl;
La Gruta, Nicole L.;
Cox, Rebecca

Publication type:

Article

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10661-8

By:

Wu, Ting;
Guan, Jing;
Handel, Andreas;
Tscharke, David C.;
Sidney, John;
Sette, Alessandro;
Wakim, Linda M.;
Sng, Xavier Y. X.;
Thomas, Paul G.;
Croft, Nathan P.;
Purcell, Anthony W.;
La Gruta, Nicole L.

Publication type:

Article

Hiding in Plain Sight: Virtually Unrecognizable Memory Phenotype CD8 + T cells.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8626, doi. 10.3390/ijms21228626

By:

Thiele, Daniel;
Gruta, Nicole L. La;
Nguyen, Angela;
Hussain, Tabinda

Publication type:

Article

The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.

Published in:

Science Immunology, 2021, v. 6, n. 58, p. 1, doi. 10.1126/sciimmunol.abe0896

By:

Lim, Jia Jia;
Jones, Claerwen M.;
Loh, Tiing Jen;
Ting, Yi Tian;
Zareie, Pirooz;
Loh, Khai L.;
Felix, Nathan J.;
Suri, Anish;
McKinnon, Murray;
Stevenaert, Frederik;
Sharma, Ravi K.;
Klareskog, Lars;
Malmström, Vivianne;
Baker, Daniel G.;
Purcell, Anthony W.;
Reid, Hugh H.;
La Gruta, Nicole L.;
Rossjohn, Jamie

Publication type:

Article

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.

Published in:

Nature, 2010, v. 467, n. 7317, p. 844, doi. 10.1038/nature09448

By:

Siew Siew Pang;
Berry, Richard;
Zhenjun Chen;
Lars Kjer-Nielsen;
Matthew A. Perugini;
King, Glenn F.;
Christina Wang;
Sock Hui Chew;
La Gruta, Nicole L.;
Williams, Neal K.;
Beddoe, Travis;
Tiganis, Tony;
Cowieson, Nathan P.;
Godfrey, Dale I.;
Purcell, Anthony W.;
Wilce, Matthew C. J.;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

Works matching AU La Gruta, Nicole L.

T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.

The clock is ticking: the impact of ageing on T cell metabolism.

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8<sup>+</sup> T cell populations.

T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.

Unlike CD4<sup>+</sup> T-cell help, CD28 costimulation is necessary for effective primary CD8<sup>+</sup> T-cell influenza-specific immunity.

The linear range for accurately quantifying antigen-specific T-cell frequencies by tetramer staining during natural immune responses.

Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion.

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude.

Evaluation of inflammation and follicle depletion during ovarian ageing in mice.

Publisher Correction: Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality.

Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality.

CD4<sup>+</sup>CD8β<sup>+</sup> double‐positive T cells in skin‐draining lymph nodes respond to inflammatory signals from the skin.

Establishment and recall of CD8<sup>+</sup> T-cell memory in a model of localized transient infection.

A question of self-preservation: immunopathology in influenza virus infection.

A naturally selected αβ T cell receptor binds HLA-DQ2 molecules without co-contacting the presented peptide.

Direct recognition of an intact foreign protein by an αβ T cell receptor.

The Role of Natural Killer Cells in the Induction of Autoimmune Gastritis.

Paired TCRαβ analysis of virus-specific CD8<sup>+</sup> T cells exposes diversity in a previously defined ‘narrow’ repertoire.

IL-18, but not IL-12, is required for optimal cytokine production by influenza virus-specific CD8.

A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8.

Peripheral T cell expansion in lymphopenic mice results in a restricted T cell repertoire.

PTPN2 attenuates T-cell lymphopenia-induced proliferation.

Sizing up the key determinants of the CD8(+) T cell response.

Immune Responses to Circulating and Vaccine Viral Strains in HIV-Infected and Uninfected Children and Youth Who Received the 2013/2014 Quadrivalent Live-Attenuated Influenza Vaccine.

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses.

Hiding in Plain Sight: Virtually Unrecognizable Memory Phenotype CD8 + T cells.

The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.