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Author Correction: A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing.
Published in:
2022
By:
- Petti, Allegra A.;
- Williams, Stephen R.;
- Miller, Christopher A.;
- Fiddes, Ian T.;
- Srivatsan, Sridhar N.;
- Chen, David Y.;
- Fronick, Catrina C.;
- Fulton, Robert S.;
- Church, Deanna M.;
- Ley, Timothy J.
Publication type:
Correction Notice
PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.
Published in:
2011
By:
- Welch, John S.;
- Wenlin Yuan;
- Ley, Timothy J.;
- Yuan, Wenlin
Publication type:
journal article
Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia.
Published in:
2010
By:
- Zhifu Xiang;
- Hui Luo;
- Payton, Jacqueline E.;
- Cain, Jennifer;
- Ley, Timothy J.;
- Opferman, Joseph T.;
- Tomasson, Michael H.;
- Xiang, Zhifu;
- Luo, Hui
Publication type:
journal article
High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples.
Published in:
2009
By:
- Payton, Jacqueline E.;
- Grieselhuber, Nicole R.;
- Li-Wei Chang;
- Murakami, Mark;
- Geiss, Gary K.;
- Link, Daniel C.;
- Nagarajan, Rakesh;
- Watson, Mark A.;
- Ley, Timothy J.;
- Chang, Li-Wei
Publication type:
journal article
Function of Transfected Globin Promoters and the Globin Locus Activator in K562 Erythroleukemia Cells<sup>a</sup>.
Published in:
Annals of the New York Academy of Sciences, 1990, v. 612, n. 1, p. 207, doi. 10.1111/j.1749-6632.1990.tb24308.x
By:
- ULRICH, MICHAEL J.;
- MOON, ANNE M.;
- LEY, TIMOTHY J.
Publication type:
Article
Regulatory Regions Flanking the Human Fetal γ-Globin Genes.
Published in:
Annals of the New York Academy of Sciences, 1989, v. 565, n. 1, p. 13, doi. 10.1111/j.1749-6632.1989.tb24145.x
By:
- LIN, HENRY J.;
- BODINE, DAVID M.;
- RUTHERFORD, TIM R.;
- ANAGNOU, NICHOLAS P.;
- McDONAGH, KEVIN T.;
- LEY, TIMOTHY J.;
- NIENHUIS, ARTHUR W.
Publication type:
Article
wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data.
Published in:
Nucleic Acids Research, 2008, v. 36, n. 7, p. e41, doi. 10.1093/nar/gkn110
By:
- Cahan, Patrick;
- Godfrey, Laura E.;
- Eis, Peggy S.;
- Richmond, Todd A.;
- Selzer, Rebecca R.;
- Brent, Michael;
- McLeod, Howard L.;
- Ley, Timothy J.;
- Graubert, Timothy A.
Publication type:
Article
Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24800-7
By:
- Smith, Amanda M.;
- LaValle, Taylor A.;
- Shinawi, Marwan;
- Ramakrishnan, Sai M.;
- Abel, Haley J.;
- Hill, Cheryl A.;
- Kirkland, Nicole M.;
- Rettig, Michael P.;
- Helton, Nichole M.;
- Heath, Sharon E.;
- Ferraro, Francesca;
- Chen, David Y.;
- Adak, Sangeeta;
- Semenkovich, Clay F.;
- Christian, Diana L.;
- Martin, Jenna R.;
- Gabel, Harrison W.;
- Miller, Christopher A.;
- Ley, Timothy J.
Publication type:
Article
Disseminated infection caused by Cunninghamella bertholletiae in a patient with beta-thalassemia. Case report and review of the literature.
Published in:
1985
By:
- Sands, Jeff M.;
- Macher, Abe M.;
- Ley, Timothy J.;
- Nienhuis, Arthur W.;
- Sands, J M;
- Macher, A M;
- Ley, T J;
- Nienhuis, A W
Publication type:
journal article
Age-related mutations associated with clonal hematopoietic expansion and malignancies.
Published in:
Nature Medicine, 2014, v. 20, n. 12, p. 1472, doi. 10.1038/nm.3733
By:
- Xie, Mingchao;
- Lu, Charles;
- Wang, Jiayin;
- McLellan, Michael D;
- Johnson, Kimberly J;
- Wendl, Michael C;
- McMichael, Joshua F;
- Schmidt, Heather K;
- Yellapantula, Venkata;
- Miller, Christopher A;
- Ozenberger, Bradley A;
- Welch, John S;
- Link, Daniel C;
- Walter, Matthew J;
- Mardis, Elaine R;
- Dipersio, John F;
- Chen, Feng;
- Wilson, Richard K;
- Ley, Timothy J;
- Ding, Li
Publication type:
Article
Erratum: The Pediatric Cancer Genome Project.
Published in:
2012
By:
- Downing, James R;
- Wilson, Richard K;
- Zhang, Jinghui;
- Mardis, Elaine R;
- Pui, Ching-Hon;
- Ding, Li;
- Ley, Timothy J;
- Evans, William E
Publication type:
Erratum
The Pediatric Cancer Genome Project.
Published in:
Nature Genetics, 2012, v. 44, n. 6, p. 619, doi. 10.1038/ng.2287
By:
- Downing, James R;
- Wilson, Richard K;
- Zhang, Jinghui;
- Mardis, Elaine R;
- Pui, Ching-Hon;
- Ding, Li;
- Ley, Timothy J;
- Evans, William E
Publication type:
Article
BreakDancer: an algorithm for high-resolution mapping of genomic structural variation.
Published in:
Nature Methods, 2009, v. 6, n. 9, p. 677, doi. 10.1038/nmeth.1363
By:
- Chen, Ken;
- Wallis, John W.;
- McLellan, Michael D.;
- Larson, David E.;
- Kalicki, Joelle M.;
- Pohl, Craig S.;
- McGrath, Sean D.;
- Wendl, Michael C.;
- Qunyuan Zhang;
- Locke, Devin P.;
- Xiaoqi Shi;
- Fulton, Robert S.;
- Ley, Timothy J.;
- Wilson, Richard K.;
- Li Ding;
- Mardis, Elaine R.
Publication type:
Article
Genetic Heterogeneity of Induced Pluripotent Stem Cells: Results from 24 Clones Derived from a Single C57BL/6 Mouse.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120585
By:
- Li, Cheng;
- Klco, Jeffery M.;
- Helton, Nichole M.;
- George, Daniel R.;
- Mudd, Jacqueline L.;
- Miller, Christopher A.;
- Lu, Charles;
- Fulton, Robert;
- O'Laughlin, Michelle;
- Fronick, Catrina;
- Wilson, Richard K.;
- Ley, Timothy J.
Publication type:
Article
Clonal Architectures and Driver Mutations in Metastatic Melanomas.
Published in:
PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0111153
By:
- Ding, Li;
- Kim, Minjung;
- Kanchi, Krishna L.;
- Dees, Nathan D.;
- Lu, Charles;
- Griffith, Malachi;
- Fenstermacher, David;
- Sung, Hyeran;
- Miller, Christopher A.;
- Goetz, Brian;
- Wendl, Michael C.;
- Griffith, Obi;
- Cornelius, Lynn A.;
- Linette, Gerald P.;
- McMichael, Joshua F.;
- Sondak, Vernon K.;
- Fields, Ryan C.;
- Ley, Timothy J.;
- Mulé, James J.;
- Wilson, Richard K.
Publication type:
Article
Expression and Function of PML-RARA in the Hematopoietic Progenitor Cells of Ctsg-PML-RARA Mice.
Published in:
PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046529
By:
- Wartman, Lukas D.;
- Welch, John S.;
- Uy, Geoffrey L.;
- Klco, Jeffery M.;
- Lamprecht, Tamara;
- Varghese, Nobish;
- Nagarajan, Rakesh;
- Ley, Timothy J.
Publication type:
Article
Visualizing tumor evolution with the fishplot package for R.
Published in:
BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-3195-z
By:
- Miller, Christopher A.;
- McMichael, Joshua;
- Dang, Ha X.;
- Maher, Christopher A.;
- Li Ding;
- Ley, Timothy J.;
- Mardis, Elaine R.;
- Wilson, Richard K.
Publication type:
Article
Reduced β-Globin Gene Expression in Adult Mice Containing Deletions of Locus Control Region 5′ HS-2 or 5′ HS-3<sup>a</sup>.
Published in:
Annals of the New York Academy of Sciences, 1998, v. 850, n. 1, p. 45, doi. 10.1111/j.1749-6632.1998.tb10461.x
By:
- LEY, TIMOTHY J.;
- HUG, BRUCE;
- FIERING, STEVEN;
- EPNER, ELLIOT;
- BENDER, M. A.;
- GROUDINE, MARK
Publication type:
Article
fgr proto-oncogene mRNA induced in B lymphocytes by Epstein-Barr virus infection.
Published in:
Nature, 1986, v. 319, n. 6050, p. 238, doi. 10.1038/319238a0
By:
- Cheah, Marc S. C.;
- Ley, Timothy J.;
- Tronick, Steven R.;
- Robbins, Keith C.
Publication type:
Article
A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11591-1
By:
- Petti, Allegra A.;
- Williams, Stephen R.;
- Miller, Christopher A.;
- Fiddes, Ian T.;
- Srivatsan, Sridhar N.;
- Chen, David Y.;
- Fronick, Catrina C.;
- Fulton, Robert S.;
- Church, Deanna M.;
- Ley, Timothy J.
Publication type:
Article
Pharmacological Manipulation of Fetal Hemoglobin Synthesis in Patients with Severe β-Thalassemia.
Published in:
Annals of the New York Academy of Sciences, 1985, v. 445, n. 1, p. 198, doi. 10.1111/j.1749-6632.1985.tb17189.x
By:
- NIENHUIS, ARTHUR W.;
- LEY, TIMOTHY J.;
- HUMPHRIES, R. KEITH;
- YOUNG, NEAL S.;
- DOVER, GEORGE
Publication type:
Article
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.
Published in:
Nature, 2008, v. 456, n. 7218, p. 66, doi. 10.1038/nature07485
By:
- Ley, Timothy J.;
- Mardis, Elaine R.;
- Ding, Li;
- Fulton, Bob;
- McLellan, Michael D.;
- Chen, Ken;
- Dooling, David;
- Dunford-Shore, Brian H.;
- McGrath, Sean;
- Hickenbotham, Matthew;
- Cook, Lisa;
- Abbott, Rachel;
- Larson, David E.;
- Koboldt, Dan C.;
- Pohl, Craig;
- Smith, Scott;
- Hawkins, Amy;
- Abbott, Scott;
- Locke, Devin;
- Hillier, LaDeana W.
Publication type:
Article
Stochastic, stage‐specific mechanisms account for the variegation of a human globin transgene.
Published in:
Nucleic Acids Research, 1998, v. 26, n. 12, p. 2849, doi. 10.1093/nar/26.12.2849
By:
- Graubert, Timothy A.;
- Hug, Bruce A.;
- Wesselschmidt, Robin;
- Hsieh, Chih‐Lin;
- Ryan, Thomas M.;
- Townes, Tim M.;
- Ley, Timothy J.
Publication type:
Article
The Physician-Scientist Career Pipeline in 2005: Build It, and They Will Come.
Published in:
JAMA: Journal of the American Medical Association, 2005, v. 294, n. 11, p. 1343, doi. 10.1001/jama.294.11.1343
By:
- Ley, Timothy J.;
- Rosenberg, Leon E.
Publication type:
Article
Physician-scientists in the United States at 2020: Trends and concerns.
Published in:
FASEB Journal, 2022, v. 36, n. 5, p. 1, doi. 10.1096/fj.202200327
By:
- Garrison, Howard H.;
- Ley, Timothy J.
Publication type:
Article
SciClone: Inferring Clonal Architecture and Tracking the Spatial and Temporal Patterns of Tumor Evolution.
Published in:
PLoS Computational Biology, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.pcbi.1003665
By:
- Miller, Christopher A.;
- White, Brian S.;
- Dees, Nathan D.;
- Griffith, Malachi;
- Welch, John S.;
- Griffith, Obi L.;
- Vij, Ravi;
- Tomasson, Michael H.;
- Graubert, Timothy A.;
- Walter, Matthew J.;
- Ellis, Matthew J.;
- Schierding, William;
- DiPersio, John F.;
- Ley, Timothy J.;
- Mardis, Elaine R.;
- Wilson, Richard K.;
- Ding, Li
Publication type:
Article
Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies.
Published in:
2017
By:
- Cole, Christopher B.;
- Russler-Germain, David A.;
- Shamika Ketkar;
- Verdoni, Angela M.;
- Smith, Amanda M.;
- Bangert, Celia V.;
- Helton, Nichole M.;
- Guo, Mindy;
- Klco, Jeffery M.;
- O'Laughlin, Shelly;
- Fronick, Catrina;
- Fulton, Robert;
- Gue Su Chang;
- Petti, Allegra A.;
- Miller, Christopher A.;
- Ley, Timothy J.;
- Ketkar, Shamika;
- Chang, Gue Su
Publication type:
journal article
PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia.
Published in:
2016
By:
- Cole, Christopher B.;
- Verdoni, Angela M.;
- Ketkar, Shamika;
- Leight, Elizabeth R.;
- Russler-Germain, David A.;
- Lamprecht, Tamara L.;
- Demeter, Ryan T.;
- Magrini, Vincent;
- Ley, Timothy J.
Publication type:
journal article
BreakTrans: uncovering the genomic architecture of gene fusions.
Published in:
Genome Biology, 2013, v. 14, n. 8, p. R87, doi. 10.1186/gb-2013-14-8-r87
By:
- Ken Chen;
- Navin, Nicholas E;
- Yong Wang;
- Schmidt, Heather K;
- Wallis, John W;
- Niu, Beifang;
- Xian Fan;
- Hao Zhao;
- McLellan, Michael D;
- Hoadley, Katherine A;
- Mardis, Elaine R;
- Ley, Timothy J;
- Perou, Charles M;
- Wilson, Richard K;
- Li Ding
Publication type:
Article
Sequencing of Tumor DNA to Guide Cancer Risk Assessment and Therapy.
Published in:
2018
By:
- Spencer, David H.;
- Ley, Timothy J.
Publication type:
journal article
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.
Published in:
Nature, 2015, v. 518, n. 7540, p. 552, doi. 10.1038/nature13968
By:
- Wong, Terrence N.;
- Ramsingh, Giridharan;
- Young, Andrew L.;
- Miller, Christopher A.;
- Touma, Waseem;
- Welch, John S.;
- Lamprecht, Tamara L.;
- Shen, Dong;
- Hundal, Jasreet;
- Fulton, Robert S.;
- Heath, Sharon;
- Baty, Jack D.;
- Klco, Jeffery M.;
- Ding, Li;
- Mardis, Elaine R.;
- Westervelt, Peter;
- DiPersio, John F.;
- Walter, Matthew J.;
- Graubert, Timothy A.;
- Ley, Timothy J.
Publication type:
Article
Mutational landscape and significance across 12 major cancer types.
Published in:
Nature, 2013, v. 502, n. 7471, p. 333, doi. 10.1038/nature12634
By:
- Kandoth, Cyriac;
- McLellan, Michael D.;
- Vandin, Fabio;
- Ye, Kai;
- Niu, Beifang;
- Lu, Charles;
- Xie, Mingchao;
- Zhang, Qunyuan;
- McMichael, Joshua F.;
- Wyczalkowski, Matthew A.;
- Leiserson, Mark D. M.;
- Miller, Christopher A.;
- Welch, John S.;
- Walter, Matthew J.;
- Wendl, Michael C.;
- Ley, Timothy J.;
- Wilson, Richard K.;
- Raphael, Benjamin J.;
- Ding, Li
Publication type:
Article
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.
Published in:
Nature, 2012, v. 481, n. 7382, p. 506, doi. 10.1038/nature10738
By:
- Ding, Li;
- Ley, Timothy J.;
- Larson, David E.;
- Miller, Christopher A.;
- Koboldt, Daniel C.;
- Welch, John S.;
- Ritchey, Julie K.;
- Young, Margaret A.;
- Lamprecht, Tamara;
- McLellan, Michael D.;
- McMichael, Joshua F.;
- Wallis, John W.;
- Lu, Charles;
- Shen, Dong;
- Harris, Christopher C.;
- Dooling, David J.;
- Fulton, Robert S.;
- Fulton, Lucinda L.;
- Chen, Ken;
- Schmidt, Heather
Publication type:
Article
Clonal Architecture of Secondary Acute Myeloid Leukemia Defined by Single-Cell Sequencing.
Published in:
PLoS Genetics, 2014, v. 10, n. 7, p. 1, doi. 10.1371/journal.pgen.1004462
By:
- Hughes, Andrew E. O.;
- Magrini, Vincent;
- Demeter, Ryan;
- Miller, Christopher A.;
- Fulton, Robert;
- Fulton, Lucinda L.;
- Eades, William C.;
- Elliott, Kevin;
- Heath, Sharon;
- Westervelt, Peter;
- Ding, Li;
- Conrad, Donald F.;
- White, Brian S.;
- Shao, Jin;
- Link, Daniel C.;
- DiPersio, John F.;
- Mardis, Elaine R.;
- Wilson, Richard K.;
- Ley, Timothy J.;
- Walter, Matthew J.
Publication type:
Article
A High-Resolution Map of Segmental DNA Copy Number Variation in the Mouse Genome.
Published in:
PLoS Genetics, 2007, v. 3, n. 1, p. 21, doi. 10.1371/journal.pgen.0030003
By:
- Graubert, Timothy A.;
- Cahan, Patrick;
- Edwin, Deepa;
- Selzer, Rebecca R.;
- Richmond, Todd A.;
- Eis, Peggy S.;
- Shannon, William D.;
- Xia Li;
- McLeod, Howard L.;
- Cheverud, James M.;
- Ley, Timothy J.
Publication type:
Article
Melanoma in a patient with DNMT3A overgrowth syndrome.
Published in:
Cold Spring Harbor Molecular Case Studies, 2023, v. 9, n. 2, p. 1, doi. 10.1101/mcs.a006267
By:
- Chen, David Y.;
- Sutton, Leslie A.;
- Ramakrishnan, Sai Mukund;
- Duncavage, Eric J.;
- Heath, Sharon E.;
- Compton, Leigh A.;
- Miller, Christopher A.;
- Ley, Timothy J.
Publication type:
Article
Whole-Genome Sequencing and Acute Promyelocytic Leukemia.
Published in:
2011
By:
- Lo-Coco, Francesco;
- Sanz, Miguel A.;
- Westervelt, Peter;
- Welch, John S.;
- Ley, Timothy J.
Publication type:
Letter
BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data.
Published in:
Bioinformatics, 2012, v. 28, n. 14, p. 1923, doi. 10.1093/bioinformatics/bts272
By:
- Chen, Ken;
- Wallis, John W.;
- Kandoth, Cyriac;
- Kalicki−Veizer, Joelle M.;
- Mungall, Karen L.;
- Mungall, Andrew J.;
- Jones, Steven J.;
- Marra, Marco A.;
- Ley, Timothy J.;
- Mardis, Elaine R.;
- Wilson, Richard K.;
- Weinstein, John N.;
- Ding, Li
Publication type:
Article
SomaticSniper: identification of somatic point mutations in whole genome sequencing data.
Published in:
Bioinformatics, 2012, v. 28, n. 3, p. 311, doi. 10.1093/bioinformatics/btr665
By:
- Larson, David E.;
- Harris, Christopher C.;
- Chen, Ken;
- Koboldt, Daniel C.;
- Abbott, Travis E.;
- Dooling, David J.;
- Ley, Timothy J.;
- Mardis, Elaine R.;
- Wilson, Richard K.;
- Ding, Li
Publication type:
Article
Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15547-8
By:
- Silva-Fisher, Jessica M.;
- Dang, Ha X.;
- White, Nicole M.;
- Strand, Matthew S.;
- Krasnick, Bradley A.;
- Rozycki, Emily B.;
- Jeffers, Gejae G. L.;
- Grossman, Julie G.;
- Highkin, Maureen K.;
- Tang, Cynthia;
- Cabanski, Christopher R.;
- Eteleeb, Abdallah;
- Mudd, Jacqueline;
- Goedegebuure, S. Peter;
- Luo, Jingqin;
- Mardis, Elaine R.;
- Wilson, Richard K.;
- Ley, Timothy J.;
- Lockhart, Albert C.;
- Fields, Ryan C.
Publication type:
Article

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