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Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin.
- Published in:
- 2019
- By:
- Publication type:
- journal article
The Protective Effect of Melatonin Against Age-Associated, Sarcopenia-Dependent Tubular Aggregate Formation, Lactate Depletion, and Mitochondrial Changes.
- Published in:
- 2018
- By:
- Publication type:
- journal article
β‐RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9<sup>R239X</sup> mice.
- Published in:
- EMBO Molecular Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.15252/emmm.201809466
- By:
- Publication type:
- Article
CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome.
- Published in:
- EMBO Molecular Medicine, 2017, v. 9, n. 1, p. 78, doi. 10.15252/emmm.201606345
- By:
- Publication type:
- Article
Melatonin treatment normalizes plasma pro-inflammatory cytokines and nitrosative/oxidative stress in patients suffering from Duchenne muscular dystrophy.
- Published in:
- Journal of Pineal Research, 2010, v. 48, n. 3, p. 282, doi. 10.1111/j.1600-079X.2010.00752.x
- By:
- Publication type:
- Article
Long-term melatonin administration protects brain mitochondria from aging.
- Published in:
- Journal of Pineal Research, 2009, v. 47, n. 2, p. 192, doi. 10.1111/j.1600-079X.2009.00700.x
- By:
- Publication type:
- Article
Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production.
- Published in:
- Journal of Pineal Research, 2009, v. 46, n. 2, p. 188, doi. 10.1111/j.1600-079X.2008.00647.x
- By:
- Publication type:
- Article
Cellular mechanisms involved in the melatonin inhibition of HT-29 human colon cancer cell proliferation in culture.
- Published in:
- Journal of Pineal Research, 2007, v. 43, n. 2, p. 195, doi. 10.1111/j.1600-079X.2007.00463.x
- By:
- Publication type:
- Article
Chronic melatonin treatment reduces the age-dependent inflammatory process in senescence-accelerated mice.
- Published in:
- Journal of Pineal Research, 2007, v. 42, n. 3, p. 272, doi. 10.1111/j.1600-079X.2006.00416.x
- By:
- Publication type:
- Article
Melatonin counteracts inducible mitochondrial nitric oxide synthase-dependent mitochondrial dysfunction in skeletal muscle of septic mice.
- Published in:
- Journal of Pineal Research, 2006, v. 40, n. 1, p. 71, doi. 10.1111/j.1600-079X.2005.00281.x
- By:
- Publication type:
- Article
Treatment of CoQ<sub>10</sub> Deficient Fibroblasts with Ubiquinone, CoQ Analogs, and Vitamin C: Time- and Compound-Dependent Effects.
- Published in:
- PLoS ONE, 2010, v. 5, n. 7, p. 1
- By:
- Publication type:
- Article
Early gender differences in the redox status of the brain mitochondria with age: effects of melatonin therapy.
- Published in:
- Hormone Molecular Biology & Clinical Investigation, 2013, v. 16, n. 2, p. 91, doi. 10.1515/hmbci-2013-0026
- By:
- Publication type:
- Article
Oxidative stress status, clinical outcome, and β-globin gene cluster haplotypes in pediatric patients with sickle cell disease.
- Published in:
- European Journal of Haematology, 2010, v. 85, n. 6, p. 529, doi. 10.1111/j.1600-0609.2010.01528.x
- By:
- Publication type:
- Article
Disruption of the NF-ΚB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-a and blocks the septic response in mice.
- Published in:
- FASEB Journal, 2015, v. 29, n. 9, p. 3863, doi. 10.1096/fj.15-273656
- By:
- Publication type:
- Article
Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ<sub>10</sub> deficiency.
- Published in:
- FASEB Journal, 2010, v. 24, n. 10, p. 3733, doi. 10.1096/fj.09-152728
- By:
- Publication type:
- Article
Attenuation of cardiac mitochondrial dysfunction by melatonin in septic mice.
- Published in:
- FEBS Journal, 2007, v. 274, n. 8, p. 2135, doi. 10.1111/j.1742-4658.2007.05755.x
- By:
- Publication type:
- Article
Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy.
- Published in:
- Oxidative Medicine & Cellular Longevity, 2019, p. 1, doi. 10.1155/2019/7187128
- By:
- Publication type:
- Article
Profilaxis antibiótica en pancreatitis aguda: No.
- Published in:
- Revista Colombiana de Gastroenterología, 2010, v. 25, n. 3, p. 270
- By:
- Publication type:
- Article
Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ<sub>10</sub> deficiency.
- Published in:
- FASEB Journal, 2008, v. 22, n. 6, p. 1874, doi. 10.1096/fj.07-100149
- By:
- Publication type:
- Article
Animal Models of Coenzyme Q Deficiency: Mechanistic and Translational Learnings.
- Published in:
- Antioxidants, 2021, v. 10, n. 11, p. 1687, doi. 10.3390/antiox10111687
- By:
- Publication type:
- Article
Metabolic Targets of Coenzyme Q10 in Mitochondria.
- Published in:
- Antioxidants, 2021, v. 10, n. 4, p. 520, doi. 10.3390/antiox10040520
- By:
- Publication type:
- Article
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism.
- Published in:
- Human Molecular Genetics, 2020, v. 29, n. 19, p. 3296, doi. 10.1093/hmg/ddaa214
- By:
- Publication type:
- Article
Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency.
- Published in:
- Human Molecular Genetics, 2013, v. 22, n. 6, p. 1233, doi. 10.1093/hmg/dds530
- By:
- Publication type:
- Article
Gene Therapy Corrects Mitochondrial Dysfunction in Hematopoietic Progenitor Cells and Fibroblasts from Coq9<sup>R239X</sup> Mice.
- Published in:
- PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0158344
- By:
- Publication type:
- Article
Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32190-y
- By:
- Publication type:
- Article
Unbalanced deoxynucleotide pools cause mitochondrial DNA instability in thymidine phosphorylase-deficient mice.
- Published in:
- Human Molecular Genetics, 2009, v. 18, n. 4, p. 714, doi. 10.1093/hmg/ddn401
- By:
- Publication type:
- Article
Thymidine kinase 2 (H126N) knockin mice show the essential role of balanced deoxynucleotide pools for mitochondrial DNA maintenance.
- Published in:
- Human Molecular Genetics, 2008, v. 17, n. 16, p. 2433, doi. 10.1093/hmg/ddn143
- By:
- Publication type:
- Article
Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport.
- Published in:
- Journal of Pineal Research, 2022, v. 73, n. 3, p. 1, doi. 10.1111/jpi.12824
- By:
- Publication type:
- Article
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
- Published in:
- Journal of Pineal Research, 2018, v. 64, n. 3, p. 1, doi. 10.1111/jpi.12461
- By:
- Publication type:
- Article
Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis.
- Published in:
- Journal of Pineal Research, 2017, v. 63, n. 1, p. n/a, doi. 10.1111/jpi.12410
- By:
- Publication type:
- Article
Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/ PINK1/ DJ-1/ MUL1 network.
- Published in:
- Journal of Pineal Research, 2016, v. 61, n. 1, p. 96, doi. 10.1111/jpi.12332
- By:
- Publication type:
- Article
Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin.
- Published in:
- Journal of Pineal Research, 2016, v. 60, n. 2, p. 193, doi. 10.1111/jpi.12303
- By:
- Publication type:
- Article
Melatonin blunts the mitochondrial/ NLRP3 connection and protects against radiation-induced oral mucositis.
- Published in:
- Journal of Pineal Research, 2015, v. 58, n. 1, p. 34, doi. 10.1111/jpi.12191
- By:
- Publication type:
- Article
A review of the melatonin functions in zebrafish physiology.
- Published in:
- Journal of Pineal Research, 2014, v. 57, n. 1, p. 1, doi. 10.1111/jpi.12149
- By:
- Publication type:
- Article
The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of i NOS and preservation of n NOS.
- Published in:
- Journal of Pineal Research, 2014, v. 56, n. 1, p. 71, doi. 10.1111/jpi.12099
- By:
- Publication type:
- Article
Analysis of the daily changes of melatonin receptors in the rat liver.
- Published in:
- Journal of Pineal Research, 2013, v. 54, n. 3, p. 313, doi. 10.1111/jpi.12019
- By:
- Publication type:
- Article
Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations.
- Published in:
- Journal of Pineal Research, 2012, v. 52, n. 2, p. 217, doi. 10.1111/j.1600-079X.2011.00931.x
- By:
- Publication type:
- Article
Synergism between melatonin and atorvastatin against endothelial cell damage induced by lipopolysaccharide.
- Published in:
- Journal of Pineal Research, 2011, v. 51, n. 3, p. 324, doi. 10.1111/j.1600-079X.2011.00892.x
- By:
- Publication type:
- Article
Inhibition of neuronal nitric oxide synthase activity by N<sup>1</sup>-acetyl-5-methoxykynuramine, a brain metabolite of melatonin.
- Published in:
- Journal of Neurochemistry, 2006, v. 98, n. 6, p. 2023, doi. 10.1111/j.1471-4159.2006.04029.x
- By:
- Publication type:
- Article
Pathomechanisms in Coenzyme Q<sub>10</sub>-Deficient Human Fibroblasts.
- Published in:
- Molecular Syndromology, 2014, v. 5, n. 3/4, p. 163, doi. 10.1159/000360494
- By:
- Publication type:
- Article
The Paradox of Coenzyme Q10 in Aging.
- Published in:
- Nutrients, 2019, v. 11, n. 9, p. 2221, doi. 10.3390/nu11092221
- By:
- Publication type:
- Article
Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases.
- Published in:
- PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0183090
- By:
- Publication type:
- Article