Works by Läubli, Heinz

Results: 43

Targeting sialic acid–Siglec interactions to reverse immune suppression in cancer.

Published in:

Glycobiology, 2018, v. 28, n. 9, p. 640, doi. 10.1093/glycob/cwx108

By:

Adams, Olivia Joan;
Stanczak, Michal A;
Gunten, Stephan von;
Läubli, Heinz

Publication type:

Article

Cancer Immunotherapy.

Published in:

Glycobiology, 2018, v. 28, n. 9, p. 638, doi. 10.1093/glycob/cwy069

By:

Pearce, Oliver M T;
Läubli, Heinz

Publication type:

Article

Sialic acids in cancer biology and immunity.

Published in:

Glycobiology, 2016, v. 26, n. 2, p. 111, doi. 10.1093/glycob/cwv097

By:

Pearce, Oliver M. T.;
Läubli, Heinz

Publication type:

Article

Detection of N-glycolylneuraminic acid-containing glycolipids in human skin.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1291292

By:

Manni, Michela;
Mantuano, Natalia Rodrigues;
Zingg, Andreas;
Kappos, Elisabeth A.;
Behrens, Anna-Janina;
Back, Jonathan;
Follador, Rainer;
Faridmoayer, Amir;
Läubli, Heinz

Publication type:

Article

Pembrolizumab-induced optic neuropathy - a case report.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1171981

By:

Daetwyler, Eveline;
Zippelius, Alfred;
Meyer, Peter;
Läubli, Heinz

Publication type:

Article

Changes of peripheral T cell subsets in melanoma patients with immune-related adverse events.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1125111

By:

Müller, Benjamin;
Bärenwaldt, Anne;
Herzig, Petra;
Zippelius, Alfred;
Maul, Lara Valeska;
Hess, Viviane;
König, David;
Läubli, Heinz

Publication type:

Article

Zelluläre Immuntherapien von Malignomen - Wie wirken sie und welche Nebenwirkungen sind zu erwarten.

Published in:

Therapeutische Umschau, 2023, v. 80, n. 8, p. 348

By:

Läubli, Heinz

Publication type:

Article

Tetra‐ and Hexavalent Siglec‐8 Ligands Modulate Immune Cell Activation.

Published in:

Angewandte Chemie, 2023, v. 135, n. 52, p. 1, doi. 10.1002/ange.202314280

By:

Conti, Gabriele;
Bärenwaldt, Anne;
Rabbani, Said;
Mühlethaler, Tobias;
Sarcevic, Mirza;
Jiang, Xiaohua;
Schwardt, Oliver;
Ricklin, Daniel;
Pieters, Roland J.;
Läubli, Heinz;
Ernst, Beat

Publication type:

Article

Response to Comment on Trinh et al. Successful Treatment of Immune Checkpoint Inhibitor-Induced Diabetes With Infliximab. Diabetes Care 2019;42:e153-e154.

Published in:

2020

By:

Trinh, Beckey;
Donath, Marc Y.;
Läubli, Heinz

Publication type:

Letter

Successful Treatment of Immune Checkpoint Inhibitor-Induced Diabetes With Infliximab.

Published in:

2019

By:

Trinh, Beckey;
Donath, Marc Y.;
Läubli, Heinz

Publication type:

Letter

Immune tumor board: integral part in the multidisciplinary management of cancer patients treated with cancer immunotherapy.

Published in:

2019

By:

Läubli, Heinz;
Dirnhofer, Stefan;
Zippelius, Alfred

Publication type:

journal article

Lenalidomide monotherapy leads to a complete remission in refractory B-cell post-transplant lymphoproliferative disorder.

Published in:

2016

By:

Läubli, Heinz;
Tzankov, Alexandar;
Juskevicius, Darius;
Degen, Lukas;
Rochlitz, Christoph;
Stenner-Liewen, Frank

Publication type:

Case Study

Therapeutic Targeting of Golgi Phosphoprotein 2 (GOLPH2) with Armed Antibodies: A Preclinical Study of Anti-GOLPH2 Antibody Drug Conjugates in Lung and Colorectal Cancer Models of Patient Derived Xenografts (PDX).

Published in:

2019

By:

Liewen, Heike;
Markuly, Norbert;
Läubli, Heinz;
Liu, Yang;
Matter, Matthias S.;
Liewen, Nora;
Renner, Christoph;
Zippelius, Alfred;
Stenner, Frank

Publication type:

journal article

The T cell repertoire in tumors overlaps with pulmonary inflammatory lesions in patients treated with checkpoint inhibitors.

Published in:

OncoImmunology, 2018, v. 7, n. 2, p. N.PAG, doi. 10.1080/2162402X.2017.1386362

By:

Läubli, Heinz;
Koelzer, Viktor H.;
Matter, Matthias S.;
Herzig, Petra;
Dolder Schlienger, Béatrice;
Wiese, Mark Nikolaj;
Lardinois, Didier;
Mertz, Kirsten D.;
Zippelius, Alfred

Publication type:

Article

Hormesis in cancer immunology.

Published in:

OncoImmunology, 2014, v. 3, n. 6, p. N.PAG, doi. 10.4161/onci.29312

By:

Pearce, Oliver MT;
Läubli, Heinz;
Bui, Jack;
Varki, Ajit

Publication type:

Article

speedingCARs: accelerating the engineering of CAR T cells by signaling domain shuffling and single-cell sequencing.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34141-8

By:

Castellanos-Rueda, Rocío;
Di Roberto, Raphaël B.;
Bieberich, Florian;
Schlatter, Fabrice S.;
Palianina, Darya;
Nguyen, Oanh T. P.;
Kapetanovic, Edo;
Läubli, Heinz;
Hierlemann, Andreas;
Khanna, Nina;
Reddy, Sai T.

Publication type:

Article

Tetra‐ and Hexavalent Siglec‐8 Ligands Modulate Immune Cell Activation.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 52, p. 1, doi. 10.1002/anie.202314280

By:

Conti, Gabriele;
Bärenwaldt, Anne;
Rabbani, Said;
Mühlethaler, Tobias;
Sarcevic, Mirza;
Jiang, Xiaohua;
Schwardt, Oliver;
Ricklin, Daniel;
Pieters, Roland J.;
Läubli, Heinz;
Ernst, Beat

Publication type:

Article

Cross-Reactivity and Functionality of Approved Human Immune Checkpoint Blockers in Dogs.

Published in:

Cancers, 2021, v. 13, n. 4, p. 785, doi. 10.3390/cancers13040785

By:

Pantelyushin, Stanislav;
Ranninger, Elisabeth;
Guerrera, Diego;
Hutter, Gregor;
Maake, Caroline;
Markkanen, Enni;
Bettschart-Wolfensberger, Regula;
Rohrer Bley, Carla;
Läubli, Heinz;
vom Berg, Johannes;
Inamura, Kentaro

Publication type:

Article

Targeting glyco-immune checkpoints for cancer therapy.

Published in:

Expert Opinion on Biological Therapy, 2021, v. 21, n. 8, p. 1063, doi. 10.1080/14712598.2021.1882989

By:

Manni, Michela;
Läubli, Heinz

Publication type:

Article

PD-1+ natural killer cells in human non-small cell lung cancer can be activated by PD-1/PD-L1 blockade.

Published in:

Cancer Immunology, Immunotherapy, 2020, v. 69, n. 8, p. 1505, doi. 10.1007/s00262-020-02558-z

By:

Trefny, Marcel P.;
Kaiser, Monika;
Stanczak, Michal A.;
Herzig, Petra;
Savic, Spasenija;
Wiese, Mark;
Lardinois, Didier;
Läubli, Heinz;
Uhlenbrock, Franziska;
Zippelius, Alfred

Publication type:

Article

The multi-receptor inhibitor axitinib reverses tumor-induced immunosuppression and potentiates treatment with immune-modulatory antibodies in preclinical murine models.

Published in:

Cancer Immunology, Immunotherapy, 2018, v. 67, n. 5, p. 815, doi. 10.1007/s00262-018-2136-x

By:

Läubli, Heinz;
Müller, Philipp;
D’Amico, Lucia;
Buchi, Mélanie;
Kashyap, Abhishek S.;
Zippelius, Alfred

Publication type:

Article

Larotrectinib Response in NTRK3 Fusion-Driven Diffuse High-Grade Glioma.

Published in:

Pharmacology, 2022, v. 107, n. 7/8, p. 433, doi. 10.1159/000524399

By:

König, David;
Hench, Jürgen;
Frank, Stephan;
Dima, Laura;
Bratic Hench, Ivana;
Läubli, Heinz

Publication type:

Article

Mechanisms of Immune-Related Complications in Cancer Patients Treated with Immune Checkpoint Inhibitors.

Published in:

Pharmacology, 2021, v. 106, n. 3-4, p. 123, doi. 10.1159/000509081

By:

König, David;
Läubli, Heinz

Publication type:

Article

Glioblastoma in the oldest old: Clinical characteristics, therapy, and outcome in patients aged 80 years and older.

Published in:

Neuro-Oncology Practice, 2024, v. 11, n. 2, p. 132, doi. 10.1093/nop/npad070

By:

Stadler, Christina;
Gramatzki, Dorothee;
Rhun, Emilie Le;
Hottinger, Andreas F;
Hundsberger, Thomas;
Roelcke, Ulrich;
Läubli, Heinz;
Hofer, Silvia;
Seystahl, Katharina;
Wirsching, Hans-Georg;
Weller, Michael;
Roth, Patrick

Publication type:

Article

Involvement of a non-human sialic acid in human cancer.

Published in:

Frontiers in Oncology, 2014, v. 4, p. 1, doi. 10.3389/fonc.2014.00033

By:

Samraj, Annie N.;
Läubli, Heinz;
Varki, Nissi;
Varki, Ajit

Publication type:

Article

A Standardized Analysis of Tertiary Lymphoid Structures in Human Melanoma: Disease Progression- and Tumor Site-Associated Changes With Germinal Center Alteration.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.675146

By:

Werner, Franziska;
Wagner, Christine;
Simon, Martin;
Glatz, Katharina;
Mertz, Kirsten D.;
Läubli, Heinz;
Griss, Johannes;
Wagner, Stephan N.

Publication type:

Article

Effects of COVID-19 Lockdown on Melanoma Diagnosis in Switzerland: Increased Tumor Thickness in Elderly Females and Shift towards Stage IV Melanoma during Lockdown.

Published in:

Cancers, 2022, v. 14, n. 10, p. 2360, doi. 10.3390/cancers14102360

By:

Kostner, Lisa;
Cerminara, Sara Elisa;
Pamplona, Gustavo Santo Pedro;
Maul, Julia-Tatjana;
Dummer, Reinhard;
Ramelyte, Egle;
Mangana, Johanna;
Wagner, Nikolaus Benjamin;
Cozzio, Antonio;
Kreiter, Saskia;
Kogler, Angelika;
Streit, Markus;
Wysocki, Anja;
Zippelius, Alfred;
Läubli, Heinz;
Navarini, Alexander Andreas;
Maul, Lara Valeska

Publication type:

Article

Gender differences in melanoma awareness, diagnosis and treatment: Patient‐reported data from a multicentre survey in Switzerland.

Published in:

Skin Health & Disease, 2024, v. 4, n. 6, p. 1, doi. 10.1002/ski2.442

By:

Mangana, Johanna;
Lamos, Cristina;
Özdemir, Berna C.;
Läubli, Heinz;
Morgan, Linda;
Maul, Lara V.;
König, David;
Dimitriou, Florentia;
Kaiser, Sandra;
Landolt, Janine;
Musiari, Anastasia;
Pasche, Nadine;
Siegenthaler, Beat;
Dummer, Reinhard;
Del Prete, Valerio

Publication type:

Article

Case report of elevation of high-sensitivity cardiac troponin T in the absence of cardiac involvement in immune checkpoint inhibitor-associated myositis.

Published in:

European Heart Journal Case Reports, 2022, v. 6, n. 9, p. 1, doi. 10.1093/ehjcr/ytac353

By:

Ruperti-Repilado, Francisco Javier;
Stouwe, Jan Gerrit van der;
Haaf, Philip;
Mueller, Christian;
Läubli, Heinz;
Pfister, Otmar;
Rothschild, Sacha I;
Kuster, Gabriela M

Publication type:

Article

Loss of Lymphotoxin Alpha-Expressing Memory B Cells Correlates with Metastasis of Human Primary Melanoma.

Published in:

Diagnostics (2075-4418), 2021, v. 11, n. 7, p. 1238, doi. 10.3390/diagnostics11071238

By:

Werner, Franziska;
Wagner, Christine;
Simon, Martin;
Glatz, Katharina;
Mertz, Kirsten D.;
Läubli, Heinz;
Richtig, Erika;
Griss, Johannes;
Wagner, Stephan N.

Publication type:

Article

Heparins Attenuate Cancer Metastasis: Are Selectins the Link?

Published in:

Cancer Investigation, 2009, v. 27, n. 5, p. 474, doi. 10.1080/07357900802647136

By:

Läubli, Heinz;
Borsig, Lubor

Publication type:

Article

Siglec receptors impact mammalian lifespan by modulating oxidative stress.

Published in:

eLife, 2015, p. 1, doi. 10.7554/eLife.06184.001

By:

Varki, Nissi;
Schwarz, Flavio;
Pearce, Oliver M. T.;
Xiaoxia Wang;
Samraj, Annie N.;
Varki, Ajit;
Garcia-Bingman, Andrea;
Secrest, Patrick;
Gagneux, Pascal;
Läubli, Heinz;
Romanoski, Casey E.;
Glass, Christopher K.;
Garcia, Javier O.;
Hongqiao Lin;
Xiaoming Fu;
Hazen, Stanley L.;
Heyser, Charles

Publication type:

Article

Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma.

Published in:

Science Translational Medicine, 2023, v. 15, n. 705, p. 1, doi. 10.1126/scitranslmed.adf5302

By:

Schmassmann, Philip;
Roux, Julien;
Buck, Alicia;
Tatari, Nazanin;
Hogan, Sabrina;
Wang, Jinyu;
Rodrigues Mantuano, Natalia;
Wieboldt, Ronja;
Lee, Sohyon;
Snijder, Berend;
Kaymak, Deniz;
Martins, Tomás A.;
Ritz, Marie-Françoise;
Shekarian, Tala;
McDaid, Marta;
Weller, Michael;
Weiss, Tobias;
Läubli, Heinz;
Hutter, Gregor

Publication type:

Article

Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment.

Published in:

Science Translational Medicine, 2022, v. 14, n. 670, p. 1, doi. 10.1126/scitranslmed.abo3605

By:

Kirchhammer, Nicole;
Trefny, Marcel P.;
Auf der Maur, Priska;
Läubli, Heinz;
Zippelius, Alfred

Publication type:

Article

NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity.

Published in:

Science Translational Medicine, 2022, v. 14, n. 653, p. 1, doi. 10.1126/scitranslmed.abm9043

By:

Kirchhammer, Nicole;
Trefny, Marcel P.;
Natoli, Marina;
Brücher, Dominik;
Smith, Sheena N.;
Werner, Franziska;
Koch, Victoria;
Schreiner, David;
Bartoszek, Ewelina;
Buchi, Mélanie;
Schmid, Markus;
Breu, Daniel;
Hartmann, K. Patricia;
Zaytseva, Polina;
Thommen, Daniela S.;
Läubli, Heinz;
Böttcher, Jan P.;
Stanczak, Michal A.;
Kashyap, Abhishek S.;
Plückthun, Andreas

Publication type:

Article

The sialoglycan-Siglec glyco-immune checkpoint – a target for improving innate and adaptive anti-cancer immunity.

Published in:

Expert Opinion on Therapeutic Targets, 2019, v. 23, n. 10, p. 839, doi. 10.1080/14728222.2019.1667977

By:

Bärenwaldt, Anne;
Läubli, Heinz

Publication type:

Article

Editorial: Novel roles for tumorassociated neutrophils.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1004772

By:

Mandruzzato, Susanna;
Läubli, Heinz

Publication type:

Article

Editorial: Glycans: Masters of immunity, from cancers to inflammatory disease.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1002679

By:

Beatson, Richard;
Läubli, Heinz;
Pearce, Oliver M. T.;
Reis, Celso A.

Publication type:

Article

B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12160-2

By:

Griss, Johannes;
Bauer, Wolfgang;
Wagner, Christine;
Simon, Martin;
Chen, Minyi;
Grabmeier-Pfistershammer, Katharina;
Maurer-Granofszky, Margarita;
Roka, Florian;
Penz, Thomas;
Bock, Christoph;
Zhang, Gao;
Herlyn, Meenhard;
Glatz, Katharina;
Läubli, Heinz;
Mertz, Kirsten D.;
Petzelbauer, Peter;
Wiesner, Thomas;
Hartl, Markus;
Pickl, Winfried F.;
Somasundaram, Rajasekharan

Publication type:

Article

Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.

Published in:

Nature Biotechnology, 2024, v. 42, n. 4, p. 597, doi. 10.1038/s41587-023-01840-6

By:

Pedram, Kayvon;
Shon, D. Judy;
Tender, Gabrielle S.;
Mantuano, Natalia R.;
Northey, Jason J.;
Metcalf, Kevin J.;
Wisnovsky, Simon P.;
Riley, Nicholas M.;
Forcina, Giovanni C.;
Malaker, Stacy A.;
Kuo, Angel;
George, Benson M.;
Miller, Caitlyn L.;
Casey, Kerriann M.;
Vilches-Moure, José G.;
Ferracane, Michael J.;
Weaver, Valerie M.;
Läubli, Heinz;
Bertozzi, Carolyn R.

Publication type:

Article

Sialic acid–binding immunoglobulin-like lectins (Siglecs) detect self-associated molecular patterns to regulate immune responses.

Published in:

Cellular & Molecular Life Sciences, 2020, v. 77, n. 4, p. 593, doi. 10.1007/s00018-019-03288-x

By:

Läubli, Heinz;
Varki, Ajit

Publication type:

Article

Tumor mutational burden assessed by targeted NGS predicts clinical benefit from immune checkpoint inhibitors in non‐small cell lung cancer.

Published in:

Journal of Pathology, 2020, v. 250, n. 1, p. 19, doi. 10.1002/path.5344

By:

Alborelli, Ilaria;
Leonards, Katharina;
Rothschild, Sacha I;
Leuenberger, Laura P;
Savic Prince, Spasenija;
Mertz, Kirsten D;
Poechtrager, Severin;
Buess, Martin;
Zippelius, Alfred;
Läubli, Heinz;
Haegele, Jasmin;
Tolnay, Markus;
Bubendorf, Lukas;
Quagliata, Luca;
Jermann, Philip

Publication type:

Article

Tools to study and target the Siglec–sialic acid axis in cancer.

Published in:

FEBS Journal, 2021, v. 288, n. 21, p. 6206, doi. 10.1111/febs.15647

By:

Läubli, Heinz;
Kawanishi, Kunio;
George Vazhappilly, Cijo;
Matar, Rachel;
Merheb, Maxime;
Sarwar Siddiqui, Shoib

Publication type:

Article